kaposi s sarcoma associatedherpesvirus molecular biologyand oncogenesis
Báo cáo sinh học: " Kaposi''''s sarcoma associated herpesvirus G-protein coupled receptor activation of cyclooxygenase-2 in vascular endothelial ce" pptx
... herpesvirus-like DNA sequences in AIDS-associated Kaposi' s sarcoma Science 1994, 266(5192):1865-1869 Cesarman E, Chang Y, Moore PS, Said JW, Knowles DM: Kaposi' s sarcoma- associated herpesvirus-like ... Degos L, Sigaux F: Kaposi' s sarcoma- associated herpesvirus-like DNA sequences in multicentric Castleman 's disease Blood 1995, 86(4):1276-1280 Ganem D: Kaposi' s Sarcoma- associated Herpesvirus In ... Anderson DJ, Ganem D, Haase AT: Kaposi' s sarcoma- associated herpesvirus gene expression in endothelial (spindle) tumor cells J Virol 1997, 71(1):715-719 Bais C, Santomasso B, Coso O, Arvanitakis...
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Báo cáo hóa học: " Kaposi''''s sarcoma associated herpesvirus G-protein coupled receptor activation of cyclooxygenase-2 in vascular endothelial cells" ppt
... herpesvirus-like DNA sequences in AIDS-associated Kaposi' s sarcoma Science 1994, 266(5192):1865-1869 Cesarman E, Chang Y, Moore PS, Said JW, Knowles DM: Kaposi' s sarcoma- associated herpesvirus-like ... Degos L, Sigaux F: Kaposi' s sarcoma- associated herpesvirus-like DNA sequences in multicentric Castleman 's disease Blood 1995, 86(4):1276-1280 Ganem D: Kaposi' s Sarcoma- associated Herpesvirus In ... Anderson DJ, Ganem D, Haase AT: Kaposi' s sarcoma- associated herpesvirus gene expression in endothelial (spindle) tumor cells J Virol 1997, 71(1):715-719 Bais C, Santomasso B, Coso O, Arvanitakis...
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báo cáo hóa học:" AIDS-associated Kaposi’s sarcoma is linked to advanced disease and high mortality in a primary care HIV programme in South Africa" pdf
... Group staging system that classifies tumour (T), immune (I) and systemic illness (S) status into good and poor risk [14] KS immune reconstitution inflammatory syndrome (IRIS) was defined as worsening ... characteristics of AIDSKS patients Males Age at time of AIDS-KS diagnosis, years Median baseline CD4+ count, cells/mm3 Follow-up time, months Disseminated Cutaneous Lesions IRIS Table Associations with mortality ... resource-limited settings are needed However, even in resource-rich countries, T 1S1 disease is associated with increased mortality (53% survival at three Yes No KS, Kaposi s sarcoma HR, Hazards ratio cART,...
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Báo cáo y học: " Seroprevalence and risk factors of Kaposi''''s sarcoma-associated herpesvirus infection among the general Uygur population from south and north region of Xinjiang, China" docx
... pathogenesis of Kaposi' s sarcoma- associated herpesvirus Phil Trans R Soc Lon Biol Sci 2001, 356: 517-534 18 Fu B, Sun F, Li B, et al: Seroprevalence of Kaposi s Sarcoma- associated Herpesvirus and Risk ... antibody titers between KSHV -infected individuals and KS patients List of abbreviations KS Kaposi sarcoma KSHV Kaposi s sarcoma- associated herpesvirus HHV-8：Human herpesvirus AIDS： acquired immunodeficiency ... progression of KSHV infection to KS development in the local minority groups Key words: Kaposi s sarcoma- associated herpesvirus (KSHV); Kaposi s sarcoma (KS); seroprevalence; Uygur people; risk...
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Báo cáo y học: " Kaposi''''s sarcoma of the hand mimicking squamous cell carcinoma in a woman with no evidence of HIV infection: a case report" pptx
... Bendsoe N: Human herpesvirus (Kaposi' s sarcoma- associated herpesvirus) DNA in Kaposi' s sarcoma lesions, AIDS Kaposi' s sarcoma cell lines, endothelial Kaposi' s sarcoma simulators, and the skin ... A) Kaposi' sabundant spindle-shaped cells HE × vascular A) Kaposi' s sarcoma consisting of angiomatoid vascular spaces and abundant spindle-shaped cells HE × 40 B) – Tumor cells are strongly positive ... immunosuppressed patients is remarkable because it may regress spontaneously if immunosuppression is reduced or discontinued These characteristics suggest that it is not a malignant neoplasm but...
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Báo cáo y học: " Kaposi''''s sarcoma associated herpes virus-encoded viral FLICE inhibitory protein activates transcription from HIV-1 Long Terminal Repeat via the classical NF-κB pathway and functionally cooperates with Tat" pptx
... [9,10] Kaposi' s sarcoma associated herpes virus (KSHV), also known as Human herpes virus (HHV8), is a γ-2 herpes virus which is frequently associated with malignancy among AIDS patients [11-13] ... human herpesvirus and apoptosis in Kaposi' s sarcoma spindle cells J Natl Cancer Inst 1999, 91:1725-33 Rainbow L, Platt GM, Simpson GR, Sarid R, Gao SJ, Stoiber H, Herrington CS, Moore PS, Schulz ... herpesvirus-8) J Gen Virol 1998, 79:1573-91 Verma SC, Robertson ES: Molecular biology and pathogenesis of Kaposi sarcoma- associated herpesvirus FEMS Microbiol Lett 2003, 222:155-63 Dourmishev...
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Báo cáo y học: "Uncovering the complexities of Kaposi’s sarcoma through genomewide expression analysis" pdf
... microarray studies of Kaposi s sarcoma (KS) Study Cells used Time analyzed (post-infection) Access to database Wang et al [1] Primary LECs and BECs and days Major findings ArrayExpress [29] Accession ... a subset of advanced cases [16], and three cell lines with chromosomal alterations have been successfully established from KS lesions, suggesting that at least some advanced cases are neoplastic ... types The nodular KS lesions used in this study were composed of over 80% spindle cells, thus minimizing dermal and epidermal contaminants The expression profile of KS lesions most closely resembled...
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Tài liệu Báo cáo khoa học: Identification of Ewing’s sarcoma protein as a G-quadruplex DNA- and RNA-binding protein ppt
... L (lanes and 2) (B) EMSA was performed with EWS (lanes 2, and 6) and 32P-labeled Htelo (lanes and 4), dsHtelo (lanes and 6) or ssDNA S (lanes and 2) The structures of DNAs used as probes are indicated ... complexes were resolved by 6% PAGE and visualized by autoradiography acids, was expressed in Escherichia coli as proteins fused to glutathione S- transferase (GST) and purified using glutathione agarose ... 4-mediated transcription J Biol Chem 278, 5427–5432 Hume DA, Sasmono T, Himes SR, Sharma SM, Bronisz A, Constantin M, Ostrowski MC & Ross IL (2008) The Ewing sarcoma protein (EWS) binds directly...
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schaum's easy outline molecular and cell biology - william stansfield, raul j cano, jaime s. colome
... Schaum s Easy Outline: Trigonometry Schaum s Easy Outline: Business Statistics Schaum s Easy Outline: Principles of Accounting Schaum s Easy Outline: Principles of Economics Schaum s Easy Outline: ... Algebra Schaum s Easy Outline: Mathematical Handbook of Formulas and Tables Schaum s Easy Outline: Precalculus Schaum s Easy Outline: Probability and Statistics Schaum s Easy Outline: Statistics Schaum s ... SCHAUM S Easy OUTLINES MOLECULAR AND CELL BIOLOGY Other Books in Schaum s Easy Outlines Series Include: Schaum s Easy Outline: Calculus Schaum s Easy Outline: College Algebra Schaum s Easy...
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báo cáo khoa học: "Contribution of magnetic resonance imaging in the diagnosis of talus skip metastases of Ewing’s sarcoma of the calcaneus in a child: a case report" pdf
... disease-free for six months after diagnosis Based on these findings, a diagnosis of Ewing s sarcoma of the calcaneus was made Discussion Ewing s sarcoma is a rare malignant neoplasm, predominantly ... patient s foot shows a hypointense tumor mass on T1-weighted spin-echo sequences compared to surrounding musculature The skip lesion of the talus displays a hyposignal on T1-weighted sequences less ... periosteal reaction and soft-tissue swelling Figure Anteroposterior radiographs of patient s foot show a lesion in the calcaneus condensed with aggressive periosteal reaction and soft-tissue swelling...
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Báo cáo y học: "Primary vaginal Ewing’s sarcoma or primitive neuroectodermal tumor in a 17-year-old woman: a case report" potx
... Finally, a diagnosis of Ewing s sarcoma/ PNET was confirmed on RTPCR with positive EWSR1-FLI1 results SYT-SSX for a synovial sarcoma was negative In five cases documented so far, only one case of vaginal ... patients Despite its aggressive behavior at osseous sites, this tumor responds to specific chemotherapy All the cases documented so far have been subjected to chemotherapy with options of surgery ... chromosomal translocation leading to a chimeric transcript EWS-FLI1 in 85% of reported cases Its presence thus confirms a diagnosis of primary Ewing s sarcoma/ PNET, especially at unusual sites where...
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Báo cáo y học: "Variations in the transcriptome of Alzheimer''''s disease reveal molecular networks involved in cardiovascular diseases" potx
... complex diseases Most studies on AD first select a set of differentially expressed genes on which further analysis is performed However, comparing lists of genes from various AD studies is not efficient ... elements in disease associated genes Figure Steps taken to analyze Alzheimer 's disease using laser capture microdissected microarray data Steps taken to analyze Alzheimer 's disease using laser capture ... these genes based on their association to human diseases resulted in the identification of 18 disease-related cardiovascular diseases (CVDs), AD/neurodegenerative diseases, stroke and diabetes)...
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Báo cáo khoa học: S-Layers as a basic building block in a molecular construction kit ppt
... proteins [6,7] S- Layer fusion proteins based on the S- layer proteins, SbsB, SbsC and SbpA, incorporate an accessible N-terminal SCWP-binding domain, the self-assembly domain, as well as a biologically ... S- Layer-coated liposomes (S- liposomes) represent simple model systems resembling features of archaeal cell or virus envelopes (Fig 5E) S- Layer proteins, once crystallized on liposomes, can be cross-linked ... genetics of S- layer proteins and mechanisms determining in vivo S- layer assembly is important As S- layer proteins represent an important class of secreted proteins, numerous S- layer genes from bacteria...
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Báo cáo khoa học: Huntington’s disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription pptx
... transcription of caspase-1, and this warrants further studies A summary of the findings that HIPPI increases apoptosis and alters gene expression is shown in Fig Hi Pro-caspase-1 45 kDa Caspase-1 20 kDa ... functions described in the preceding sections The evidence that HIPPI directly or indirectly alters gene expression comes from the observations that caspase-1, caspase-3, caspase-7, caspase-8 and caspase-10 ... expressions In turn, increased pro-caspase-8 is recruited to HIPPI–HIP-1 heterodimer and increases apoptosis The role of caspase-1 in apoptosis is not known, but in some conditions it may increase...
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molecular biology of human cancers an advanced student's textbook - wolfgang a. schulz
... replicative senescence) Invasion into different tissue layers and other tissues (with disturbed tissue architecture) Metastasis into local lymph nodes and distant tissues Insufficient apoptosis: Cell ... some non-cancerous diseases For instance, atherosclerosis can also with some right be regarded as a tumor disease In general, an increased number of cells in a tissue is designated ‘hyperplasia’ ... 100, 57-70 Several staging systems are employed The most widely used and systematic staging system is the TNM classification, while others remain in use for specific cancers In the TNM system, the...
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Báo cáo khoa học: "Primary Kaposi sarcoma of the subcutaneous tissue" ppsx
... nonspecific [16] CT is also helpful in assessing the involvement of deep tissue planes as well as the extent of possible nodal disease Earlier imaging modalities, such as scintigraphy with sequential thallium ... diagnosis of a subcutaneous thigh mass in an HIV-positive person is broad and includes infection (e.g abscess, cryptococcus), reactive/benign conditions (e.g nodular fasciitis), benign neoplasms ... biopsy of Kaposi sarcoma Fascicles comprised of spindled tumor cells are shown (H&E stain) no findings prior to biopsy in our case that were particularly indicative of infection Soft tissue abscess...
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Báo cáo y học: "ertheim cung cấp cho các bạn kiến thức về ngành y đề tài: The prognostic significance of facial lymphoedema in HIV-seropositive subjects with Kaposi sarcoma" pps
... Boshoff C: Kaposi sarcoma herpesvirus-induced cellular programming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma Nat Genet 2004, 36:687-693 Schwartz AA: Kaposi' s sarcoma: ... Williams WH, Szabo J: Lymphangioscintigraphy in AIDS-associated Kaposi sarcoma AJR 1990, 155:311-315 Ramdial PK, Chetty R, Singh B, Singh R, Aboobaker J: Lymphedematous HIV-associated Kaposi' s sarcoma ... angiogenesis and neovascularization both of lymphatics and of blood vessels, lipid deposition, subcutaneous fibrosis and hyperkeratosis In addition, stasis of lymph implies failure of transport...
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báo cáo khoa học: " AIDS-Kaposi Sarcoma and Classic Kaposi Sarcoma: are different ultrasound patterns related to different variants?" doc
... KS variants Figure Vascular aspects of Classic KS Classic Kaposi Sarcoma lesion, with slight vascularisation (only one vascular pole), in a small superficial hypoechoic lesion, is evident Solivetti ... associated to ectasia of local-regional vessels in adipose sub-cutaneous tissue consisting of irregularly dilated canals, which to varying degrees were associated with bundles of spindle cells ... vascularisation was rare in CKS lesions (Table 1), whereas it was almost always present in AIDS-KS For the AIDSKS patients, it can be hypothesized that vascularization was related to an intense...
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