ischemia reperfusion injury of the kidney with mesenchymal stromal cells
Báo cáo y học: "Ischemic preconditioning reduces the severity of ischemia-reperfusion injury of peripheral nerve in rat" pptx
... ischemia with minute's intervals), and then hours of ischemia with hours of reperfusion Part 2: Long time effetcs of I/R and IP Group 1- I/R with long duration (7dR):4 hours of ischemia and days of reperfusion ... Group 2- Preconditioning plus I/R with long duration (7dR+IP): The same preconditioning protocol with the group IV, and then, hours of ischemia with following days of reperfusion In both groups, sciatic ... days of reperfusion A total of 70 rats were used in the study The study was divided into two part Part included the biochemical examination of Ischemia, I/R and I/R+IP on sciatic nerves of rats...
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Báo cáo y học: " Penetrating injury of the hand with a door handle: a case report" ppt
... was involved with the initial writing of the manuscript including the literature search MK was involved with the initial management of the patient and reviewed the manuscript NS was the senior ... publication of this case report and accompanying images A copy of the written consent is available for review by the Editor-in-Chief of this journal Competing interests The authors declare that they ... removal of a foreign body or surgical exploration of a puncture wound is decided upon, it must be performed under adequate anaesthesia and tourniquet control [5] Attention to the integrity of the...
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Báo cáo y học: "Primitive neuroectodermal tumour of the kidney with vena caval and atrial tumour thrombus: a case report" docx
... (CT) of the thorax and the abdomen MRI of the kidney revealed a large 13 cm, right encapsulated, lower-aspect renal mass with tumour thrombus extending into the right renal vein, IVC and into the ... which replaced most of the kidney with only a small amount of uninvolved parenchyma at the lower pole Haematoxylin and eosin staining showed the tumour to comprise cohesive sheets of small, uniform, ... tumor (PNET) of the kidney: a case report BMC Cancer 2004, 4:3 Parham DM, Roloson GJ, Feely M, Green DM, Bridge JA, Beckwith JB: Primary malignant neuroepithelial tumors of the kidney: a clinicopathologic...
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Báo cáo sinh học: "The combined transduction of copper, zincsuperoxide dismutase and catalase mediated by cell-penetrating peptide, PEP-1, to protect myocardium from ischemia-reperfusion injury" ppt
... and ischemia- reperfusion injury To observe whether transduced PEP-1-SOD1 and PEP-1CAT protect myocardial ischemia- reperfusion injury in Page of 11 vivo, we established the model of myocardial ischemiareperfusion ... from ischemia- reperfusion injury Page of 11 Materials and methods The present study conformed to the Guide for the Care and Use of Laboratory Animals published by the US National Institutes of ... cardiomyocyte H9c2 cells The levels of LDH in the supernatants and the apoptosis of cells were indicators of hypoxiareoxygenation injury [25,26] Our previous studies have shown that application of PEP-1-SOD1...
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Báo cáo khoa học: "Attenuation of ischemia-reperfusion injury by ascorbic acid in the canine renal transplantation" pps
... erofeb seitivitca TAC dna xPHSG puorg tnemtaert dna lortnoc eht neewteb secnacifingis lacitsitats ;50.0 < p* spuorg htob rof DS ± naem sa desserpxe era seulav ehT noisufreper fo h 27 yb dewollof ... puorg tnemtaert susrev lortnoc rof secnacifingis lacitsitats ;50.0 < p* spuorg htob rof DS ± naem eht sa desserpxe era seulav ehT noisufreper fo h 27 yb dewollof noitatnalpsnartotua laner retfa ... a rof nekat erew yendik tfel eht morf selpmas eussit ehT ld/gm 8.1< ot dezilamron dah seulav eninitaerc mures eht fi keew tnalpsnart-tsop driht eht retfa seninac gnivivrus eht gnizinahtue rof...
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Báo cáo y học: "Beneficial effect of the oxygen free radical scavenger amifostine (WR-2721) on spinal cord ischemia/reperfusion injury in rabbits" docx
... observed within the same group (Figure 1) Blood tests Blood results tests obtained at the onset of the procedure, after the aorta release and the administration of the agent and at the end of the ... min) intra-aortically via the Peripheral Dilatation Catheter line, by the onset of reperfusion After 75 of reperfusion the animals were sacrificed with lethal doses of Propofol and Fentanyl [15] ... after ischemiareperfusion injury have been proved, we have planned the extension of the experiment with focus to the post operative neurological status of the animals Conclusion In conclusion, the...
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Báo cáo sinh học: "Adipose-Derived Mesenchymal Stem Cell Protects Kidneys against Ischemia-Reperfusion Injury through Suppressing Oxidative Stress and Inflammatory Reaction" ppt
... cause the damage of renal parenchyma and destroy the architectural integrity of the kidney One important finding in the current study is that the mRNA expressions of TNF-1a and MMP-9 as well as the ... days, majority of isolated adipose-derived stem cells expressing CD29 and CD90 characteristic of mesenchymal stem cells (n = 3) Note the spindle-shaped morphological feature of the stem cells (Right ... focused on the therapeutic impact of ADMSC on acute renal injury using a rodent model of renal IR, the effects of ADMSC administration were followed only up to 14 days after IR injury without looking...
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báo cáo hóa học:" Salter-Harris II injury of the proximal tibial epiphysis with both vascular compromise and compartment syndrome: a case report" docx
... incidence of 0.5% [1] Burkhart The described mechanism of injury is direct impact to the proximal tibia with the knee in extension or hyperextension, with or without valgus or varus strain [5] The ... was the surgeon in charge of the patient described with in this report NC conducted the literature review and analysed the gathered reports for the described injury NC composed and wrote the ... throughout the literature is the difficulty in maintaining the reduction with cast alone, especially with posterior displacement of the tibia [2-10] The majority of reports used conservative...
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Báo cáo khoa học: " Influence of ascorbic acid on BUN, creatinine, resistive index in canine renal ischemia-reperfusion injury" pps
... esaercni tpurba detartsnomed nim 09 rof aimehcsi gniwollof noisufreper laner ,yduts suoiverp a nI puorg lortnoc ni detartsnomed erew noisufreper retfa syad 41 dna erofeb yletaidemmi seulav erapmoc ... raluremolg eht ni esaerced eht rof sisab eht eb ot deredisnoc si hcihw elubut eht fo nemul otni sdehs dna sisotpopa /sisorcen seogrednu tnemges lamixorp eht ,eroferehT ]9[ aimehcsi cimrehtomron ... morf gnirevocer retfa retaw dna doof dewolla erew slamina ehT enidoi-enodivop %01 gniylppa yb dezilirets saw dnuow eht dna desolc saw ytivac lanimodba ehT demrofrep saw ymotcerhpen thgir eht neht...
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báo cáo khoa học: "Metastatic collecting duct carcinoma of the kidney treated with sunitinib" potx
... Considering these findings in addition to the characteristics of CDC similar to those of urothelial cancer, chemotherapy is the currently favored approach for patients with metastatic CDC In the case ... was treated with sunitinib rather than systemic chemotherapy, considering her poor performance status After courses of sunitinib therapy with 37,5 mg daily schedule, metastases to the lungs and ... Although the precise molecular mechanism involved in the antitumor activity of multiple tyrosine kinase inhibitors against CDC remains largely unknown, these findings suggest that the efficacy of these...
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Báo cáo y học: "The role of mast cells and fibre type in ischaemia reperfusion injury of murine skeletal muscles" pot
... reperfusion Unlike other models [6], the extended reperfusion period permits full manifestation of the reperfusion injury In order to determine the usefulness of therapies against mast cells, it is ... variation in the period of ischaemia, the muscle temperature during ischaemia and the period of reperfusion allowed for manifestation of the reperfusion injury Idstrom [12] utilised a period of 2, and ... restores the susceptibility of skeletal muscles to IR injury irrespective of the other abnormalities in these mice The role of mast cells has not been considered when investigating the susceptibility...
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Báo cáo y học: "Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts" pps
... continued reperfusion Pretreatment with Desmodium gangeticum increased the recovery of the rate pressure product in the drug group (60% of basal value) compared with the reperfusion group (35% of basal ... the normal physiological functions of hearts The cardiac damage due to ischemia reperfusion was monitored by the presence of cardiac marker enzymes in the cardiac perfusate and the level of these ... also enhanced the recovery of antioxidant enzymes from the assault of ischemia reperfusion injury (Table 4) Conclusion The ethyl acetate extract of Desmodium gangeticum root protects the myocardium...
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Role of cyclic AMP signalling mechanisms in heart protection against ischemia reperfusion injury
... effectively protects heart against ishaemia /reperfusion injury PKA and Epac act synergicaly in the cardioprotective effect of cAMP Scheme of Signal Transduction of the cAMPInduced Cardioprotection cAMP ... AMP-induced activation of PKA (due to heart perfusion with isoproterenol) depletes glycogen in myocardium This promotes binding of Hexokinase II to the mitochondrial membrane and inhibition of mitochondria ... activation of PKA by (due to heart perfusion with isoproterenol) depletes glycogen in myocardium This promotes binding of Hexokinase II to the mitochondrial membrane and inhibition of mitochondria...
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Hydrogen sulfide produces cardioprotective effects against ischemia reperfusion injury via regulation of intracelluar PH
... enzymes are the main players in the metabolism of L-cysteine (Hughes, Bundy et al 2009) which is the main substrate of the generation of H2S The expression of these two enzymes is highly tissue-specific; ... from the peak of alkalinization due to efflux of HCO3- via activity of CBE, that is, a recovery from alkali load (Xu and Spitzer 1994) The slope of the pHi decrease determines the rate of recovery ... always lead to the disturbances in the blood movement and the interference in transfer of O2 and glucose into the cells To examined the effect of NaHS on contractile function of isolated heart...
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Báo cáo y học: " Experimental ablation of the pancreas with high intensity focused ultrasound (HIFU) in a porcine model"
... compliance with the guide for the care and use of laboratory animals from the Ministry of Science and Technology of the People’s Republic of China Instruments HIFU ablation was performed with a HIFU ... leading the coagulation necrosis of the whole target regions During the therapeutic process, real-time estimation of the therapeutic effect was carried out by the computer system through the graphic ... used as the real-time imaging unit of the system, guiding the target tissue volume, monitoring the energy deposition and the therapeutic effect, and also controlling the US exposure based on the...
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Báo cáo y học: "ntravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head"
... 1B) The infection rate was over 70% Flow cytometry showed the MSCs had no expressions of CD34, CD45 and HLA-DR, but high expressions of CD29 and CD44 Furthermore, the purity of cells with these ... and safe Another concern of intravenous transplantation of MSCs is whether the MSCs can migrate into and proliferate in the target tissues, which is the basis of therapeutic effects of MSCs In ... especially in the necrotic femoral heads, the mechanisms underlying the directional migration of MSCs should be further studied Besides, the efficacy of intravenous transplantation of MSCs in the treatment...
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Báo cáo y học: "ISOLATION OF CHLAMYDIA PNEUMONIAE FROM SERUM SAMPLES OF THE PATIENTS WITH ACUTE CORONARY SYNDROME"
... specificity of the primers and probe Real-time PCR was performed with the iCycler IQ ystem (Biorad, USA) µl of extracted DNA was analyzed with the PCR mixture in a total volume of 25 µl The PCR 184 ... PCR product of predicted size (194 bp) The TaqMan probe was labelled at the 5' end with 6-carboxyfluorescein as the reporter dye and at the 3' end with 6-carboxytetramethylrhodamine as the quencher ... efficiently propagate in blood cells, in particular in mononuclear cells and lymphocytes (16,17,18) The presence of C pneumoniae in the blood cells predetermines the possibility of pathogen dissemination...
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CORREGGIO A COLLECTION OF FIFTEEN PICTURES AND A SUPPOSED PORTRAIT OF THE PAINTER, WITH INTRODUCTION AND INTERPRETATION pot
... figures of the four Evangelists, each one accompanied by one of the four Fathers of the Church The[ 38] Christian Fathers were the men whose writings and teachings shaped the doctrines of the faith ... hand the lily, which is the symbol of purity The other two figures, of which we see only the upper portion, are Fortune, with a cornucopia, and the helmeted Athena, with spear and torch At the ... faith in the early centuries of our era They interpreted for the people the meaning of the Scriptures and the Gospels The pendentive of our illustration contains St John with St Augustine The two...
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