integra® extracellular matrix of collagen and chondroitin 6 sulfate
Báo cáo y học: "Relaxin''''s induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint" ppsx
... degradation – effects of a matrix metalloproteinase inhibitor Ann Rheum Dis 1995, 54 :66 2 -66 9 28 Chandrasekhar S, Esterman MA, Hoffman HA: Microdetermination of proteoglycans and glycosaminoglycans ... age and gender distribution of TMJ diseases Furthermore, these findings have potential physiologic relevance because the induction of collagenase-1 and stromelysin-1 and the loss of collagen and ... because GM6001 has a low dissociation constant for both collagenase-1 and stromelysin-1 [30], and their induction by relaxin was accompanied by a loss of their matrix substrates, collagenase-1 and...
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Báo cáo y học: "Regulatory polymorphisms in extracellular matrix protease genes and susceptibility to rheumatoid arthritis: a case-control study" ppsx
... A/G and -153 C/T), between the MMP1 - 160 7 1G/2G and MMP3 -1171 6A/5A SNPs, and between MMP13 -77 A/G and two other SNPs (MMP3 -1171 6A/5A and MMP7 -153 C/T) Comparison of the frequencies of the ... MMP13 -77 A/G A 68 .0 65 .6 1.13 0.2 1.09 Up PLAT -7351 C/T T 36. 4 32.1 1.21 0.03 1.20 Down PAI-1 -67 5 5G/4G 4G 47 .6 46. 8 1.03 0.7 1.05 Up Frequency values for rheumatoid arthritis (RA) and controls ... - 160 7 1G/2G (rs1799750); MMP2 -13 06 C/T (rs243 865 ); MMP3 -1171 6A/5A (rs3025058); MMP7 181 A/G and -153 C/T; MMP9 -1 562 C/T (rs3918242); MMP13 -77 A/G (rs2252070); PLAT -7351 C/T (rs2020918); and...
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Synthesis and electrochemical preformances of tribasic and tetrabasic lead sulfates prepared by reactive grinding docx
... were commercial STREM PbO Žmixtures of a- and b-PbO., commercial PROLABO lead sulfate, and pure PbO P PbSO4 prepared by reaction of 5 .62 g PbO with 3.01 g H SO4 and 172 g H O at room temperature ... of finely divided and reactive ground precursors to prepare both 3BS and 4BS powders In this paper will be discussed: Ži the new synthesis route for 3BS and 4BS phases and the morphological and ... nucleation of 3BS takes place at the oxide surface leading to the coating of the small grains of PbO by the basic lead sulfate phase Encapsulated PbO grains cannot react with the sulfate ions of the...
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Báo cáo y học: "Osteogenic protein 1 in synovial fluid from patients with rheumatoid arthritis or osteoarthritis: relationship with disease and levels of hyaluronan and antigenic keratan sulfate" ppt
... Female 42 Female 73 Female 56 Female 26 Female 41 Male 62 Male 53 Female 66 Female 10 66 Female 11 26 Female 12 26 Female 13 73 Female 14 42 Female 15 34 Female 16 49 Female 17 70 Male 18 53 ... first report of the presence of OP-1 in the SF of asymptomatic organ donors, of OA patients, and of RA patients, and report statistical differences between the SF concentrations of this growth ... 3, chondroitinase ABC (0.1 U/ml); lane 4, combination of hyaluronidase (50 units/ml) and chondroitinase ABC (0.1 U/ml) The numbers on gels represent the size of the protein bands of interest and...
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Báo cáo y học: "Adipose-derived mesenchymal stem cells from the sand rat: transforming growth factor beta and 3D co-culture with human disc cells stimulate proteoglycan and collagen type I rich extracellular matrix" ppsx
... presence of chondroitin sulphate and keratin sulphate (Figures 4a–d), types I and II collagen and decorin (data not shown) Localisation of the ECM proteins was present in cell layers on margins of ... Stimulation of AD-MSC to increase proteoglycan and collagen type I production To increase proteoglycan and collagen type I production, 3D cell culture and exposure to TGFβ were used Growth and differentiation ... assay [ 26] Scoring of immunohistochemistry and toluidine blue staining Scoring of slides from immunohistochemical staining of cellsurface markers, ECM proteins and toluidine blue staining of total...
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Báo cáo y học: "Cartilage oligomeric matrix protein deficiency promotes early onset and the chronic development of collagen-induced arthritis" pdf
... Figure Schematic picture of interactions of cartilage oligomeric matrix protein (COMP) with collagen II and collagen IX In cartilage, collagen II is the main IX collagen and makes up a fiber network ... induced arthritis and rheumatoid arthritis J Immunol Methods 2005, 304:1 26- 1 36 Liljander M, Sallstrom MA, Andersson S, Andersson A, Holmdahl R, Mattsson R: Identification of collagen- induced arthritis ... 2002, 22:4 366 -4371 Carlsen S, Nandakumar KS, Holmdahl R: Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity Arthritis Res Ther 20 06, 8:R102...
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Báo cáo y học: "Transcriptional regulation of matrix metalloproteinase-1 and collagen 1A2 explains the anti-fibrotic effect exerted by proteasome inhibition in human dermal fibroblasts" docx
... WC: Control of matrix metalloproteinase catalytic activity Matrix Biol 2007, 26: 587-5 96 Clark IM, Swingler TE, Sampieri CL, Edwards DR: The regulation of matrix metalloproteinases and their inhibitors ... activation of Ras signalling pathway Biochem J 20 06, 398:215-224 doi: 10.11 86/ ar2991 Cite this article as: Goffin et al., Transcriptional regulation of matrix metalloproteinase-1 and collagen 1A2 ... downregulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts FASEB J 20 06, 20: 562 - 564 Inayama M, Nishioka...
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Báo cáo y học: " Collaborative interactions between neutrophil elastase and metalloproteinases in extracellular matrix degradation in threedimensional collagen gels" pps
... Co-culture of monocytes and fibroblasts increased both bands of MMP-2 and resulted in more of the 66 kDa form (Fig 1b) Co-culture of fibroblasts with monocytes also induced the release of MMP-9 ... co-cultures of fibroblasts and monocytes augmented collagen gel contraction and degraded the extracellular matrix NE added to co-cultures resulted in a concentration-dependent degradation of collagen ... Mechanisms of activation of tissue procollagenase by matrix metalloproteinase (stromelysin) Biochemistry 1990, 29:10 261 10270 28 Brown PD: Synthetic inhibitors of matrix metalloproteinases In Matrix...
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Báo cáo y học: "The integrins are a superfamily of cell adhesion receptors that bind to extracellular matrix ligands, cell-surface ligands, and soluble ligands. They are transmembrane α" ppsx
... cytoplasmic domain, and also to signal extracellular ligand binding back to the inside of the cell Much of our current knowledge of the myriad of functions attributed to ligand binding of a particular ... the ligand-binding pocket of the headpiece that increase its affinity for ligand The affinity directly regulates the nature of the ligand binding and appears to tune the degree and kinetics of cell ... NM_005501 17q21.33 P 260 06 ITGA4 α4 CD49d, α4 subunit of VLA-4 NM_000885 2q31.3 AAB254 86 ITGA5 α5 CD49e, fibronectin receptor alpha NM_002205 12q11-q13 P0 864 8 ITGA6 6 CD49f, ITGA6B NM_000210 2q31.1...
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Báo cáo y học: " Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions" pps
... - 62 7 79 Prostate BPH - 66 2 66 Prostate BPH - 66 5 53 Prostate 63 ± 18.4 66 7 47 Prostate 61 ± 4.2 68 7 63 Prostate 74 69 0 79 Prostate BPH - 69 3 75 Prostate BPH - 704 64 Prostate (HR) - 003/ 06 52 ... 99 ± 56 484 69 Prostate 105 ± 29 512 74 Prostate BPH - 561 72 Prostate BPH - 563 64 Prostate 35 ± 9.5 75 ± 569 64 Prostate 574 74 Prostate BPH/G6 (5%) - 60 5 56 LN metastasis 119 ± 21 66 1 78 Prostate ... Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells Cancer Res 2002, 62 :66 59 -66 66 Patterson SG, Wei...
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Mechanical characterization of biopolymer and the effects of mechanical properties of extracellular matrix on cell behaviours
... CHARACTERIZATION OF BIOPOLYMER AND THE EFFECTS OF MECHANICAL PROPERTIES OF EXTRACELLULAR MATRIX ON CELL BEHAVIORS WONG LONG HUI (B.Eng.(Hons.), NTU) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... the complexity of science and profundity of life Prof Too’s lessons extended far beyond the laboratory – from politics and current issues to virtues of integrity, honest work and humility Especially ... microspheres Biomechanics and Modeling in Mechanobiology (Chapter 3) Kurniawan, N A., Wong, L H, and Rajagopalan, R (2012) Early Stiffening and Softening of Collagen: Interplay of Deformation Mechanisms...
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n vitro bioassembled human extracellular matrix and its application in human embryonic stem cell cultivation 6
... 199(2):174-80 (2004) 62 Hohenester E, Engel J Domain structure and organisation in extracellular matrix proteins Matrix Biol 21(2):115-128 (2002) 63 Schönherr E, Hausser HJ Extracellular matrix and cytokines: ... Tryggvason K, Martin GR Isolation and characterization of type IV procollagen, laminin and heparin sulfate proteoglycan from the EHS sarcoma Biochem 21 :61 88 -61 93 (1981) 20 Kleinman HK, McGarvey ... Lancet 365 : 163 6- 164 1 (2005) 37 Holmes TC, Lacalle Sd, Liu G, Rich A, Zhang S Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds PNAS 97(2) :67 28 -67 33 (2000)...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 6) ppt
... outline of an incident (retrospective diagnostic system) A place of incident, a matrix of poison, severity of poisoning, the number of victims, described in news reports, were chosen and patterned, ... metabolism and toxicity of fluorine compounds (especially hydrogen fluoride) Mechanisms of induction of cytochrome p-450 caused by drugs and poisons Studies on neurotoxicity of chemicals Mechanisms of ... chemicals Chemical and toxicological changes of organic compouns by chlorine treatments, and production mechanisms of dioxins Sensitive analysis of trace drugs and poisons by LC/MS and GC/MS Immunoassay...
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Tài liệu Báo cáo khoa học: Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen pdf
... 585 60 7) and MT5MMP (amino acids 62 3 64 5) ICDs MT1-MMP (VP16MT1 Y, VP 16- MT1 LL, VP 16- MT1 FRR, VP 16- MT1 HGT, VP 16- MT1 PRR, VP 16- MT1 LLY, VP 16- MT1 CQR, VP 16- MT1 SLL, VP 16- MT1 DKV), MT2-MMP (VP 16- MT2 ... amplified by PCR and cloned downstream of EYFP VP 16- PC5/6B, VP 16- PC7 and VP 16- furin were generated by fusing VP 16 to ICDs of mouse PC5/6B (amino acids 1 461 –1548), human PC7 (amino acids 68 4– 785) or ... 400 500 + VP 16 + VP 16 + VP 16 + VP 16 MT1 MT1 C GAL4 + VP 16 GAL4 GRASP55 + VP 16 GAL4 + VP 16 TGF-α GAL4 GRASP55 + VP 16 TGF-α A GAL4 + VP 16 MT1 GAL4 GRASP55 + VP 16 MT1 GAL4 GRASP55 + VP 16 MT1 FRR GAL4...
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Tài liệu Báo cáo khoa học: 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5¢-phosphate synthases of fungi and archaea docx
... velocities of 3.8S for C glabrata and 3.5S for A aeolicus (Fig 3A and Fig S2A) Sedimentation equilibrium analysis indicated relative masses of 57.8 kDa (C glabrata) and 50 .6 kDa (A aeolicus) (Fig 3B and ... were of two types, either with the two-domain architecture of the RibG protein of Bacillus subtilis or the RibD protein of E coli, respectively [18–20], or the single-domain type of 2,5-diamino-6ribitylamino-4(3H)-pyrimidinone ... P25539); BACSU, RibD protein of Bacillus subtilis (accession number P1 761 8); AQUAE1, RibD protein of Aquifex aeolicus (accession number O 665 34); PSESY1, RibD protein of Pseudomonas syringae pv...
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Tài liệu Báo cáo khoa học: Membrane orientation of laminin binding protein An extracellular matrix bridging molecule of Leishmania donovani pdf
... localization of the laminin binding protein As a part of molecular mechanism underlying the invasion of the extracellular matrix of solid organs like liver and The hydrophobic nature of LBP was ... to be extracellular [28] Amino acid sequencing of intact and CNBr fragments of both the LBP and the trypsin-released ectodomain establishes that both of them share a blocked N terminus and an ... Identification and purification of membrane and soluble forms of the major surface protein of Leishmania promastigotes J Biol Chem 260 , 15504– 15509 14 Leary, J.J., Brigati, D.J & Ward, D.C (1983) Rapid and...
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Tài liệu A General History and Collection of Voyages and Travels, Vol. 6 pptx
... _Grant by Edward VI of a Pension, and the Office of Grand Pilot of England to Sebastian Cabot_[18] Edward the Sixth, by the Grace of God king of England, France, and Ireland, to all believers ... Description of that place Two thousand men desert from the Gallies Tor Island of Soridan Port of Kor II Arrival at Jiddah, the Port of Mecca The islands of Alfas, Kamaran, and Tuiche The Straits of Bab-al-Mandub ... along and beyond this land of New France in the employment of Henry VII of England He informed me that, having sailed a long way to the north-west, beyond these lands, to the lat of 67 -1/2° N and...
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Tài liệu Improving Fourth Grade Students’ Writing Skills With 6+1 Traits of Writing and Writer’s Workshop ppt
... produce a more accurate and holistic portrait of the student (Adams, 19 96, p 20) 6+ 1 Traits of Writing 6+ 1 Traits of Writing “is a vocabulary teachers use to describe their vision of what good writing ... (SAGE) School During the year of this study, I taught three sections of English with a total of 61 students A wide range of my students’ abilities and the presence of English Language Learners ... implementation of selected lessons and activities taken from 6+ 1 Traits of Writing and Writer’s Workshop equip my students with the descriptive and mechanical writing skills they need to become proficient...
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Báo cáo khoa học: Thermodynamic characterization of substrate and inhibitor binding to Trypanosoma brucei 6-phosphogluconate dehydrogenase pot
... complexes of 6PGDH from Trypanosoma brucei ND, not determined Titrant Binary complex aPyADP NADPH NADP NADP NADPH 6PG 4PE 6PGDH)6PG 6PGDH)6PG 6PGDH)5PR 6PGDH)4PE 6PGDH)4PE 6PGDH–aPyADP 6PGDH–NADP 3 .62 ... calorimetry of T brucei 6PGDH + aPyADP +2 6PG E-6PG2 E +2 aPyADP [E-aPyADP] E-aPyADP2 E-aPyADP-6PG2 - aPyADP +2 6PG Scheme Kinetic mechanism of the binding to 6PGDH of the substrate 6PG and the NADP ... ± 0.79 3.5 0.95 0.13 173.8 ) 1330 ) 2381 7398 66 26 5111 ) 0. 46 ) 0.018 ) 0.029 1.47 ± 0. 06 1.33 ± 0.1 1.83 ± 0.3 64 28 FEBS Journal 274 (2007) 64 26 64 35 ª 2007 The Authors Journal compilation ª...
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Báo cáo khoa học: Connection of transport and sensing by UhpC, the sensor for external glucose-6-phosphate in Escherichia coli ppt
... wild-type) 63 110 100 110 3.8 135 30 23 46 82 33 145 45 73 150 115 105 154 30 61 31 75 145 152 1 06 100 22 39 13 37 32 93 81 63 67 128 480 395 231 24 67 8 97 81 179 241 158 78 n.m 264 6 0. 86 3.2 Constitutivea ... for function of UhpC as transporter and sensor? Although most of the residues mutated in UhpC are highly conserved in UhpC and UhpT proteins (Fig 2), and in the case of R 46 and R 266 had been shown ... effects of the arginine mutations on induction were large and varied The concentration of Glc6P that gave 50% induction of UhpT increased from 3.8 lM to 932 lM in R 266 C, to 264 6 lM in R149C, and...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose