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in vitro wear testing of conventional versus sequentially cross linked polyethylene liners in combination with different sizes of ceramic femoral heads

Báo cáo khoa học: The in vitro effects of CRE-decoy oligonucleotides in combination with conventional chemotherapy in colorectal cancer cell lines potx

Báo cáo khoa học: The in vitro effects of CRE-decoy oligonucleotides in combination with conventional chemotherapy in colorectal cancer cell lines potx

Báo cáo khoa học

... alone did not increase the extent of staining However, in cells that had been cocultured with CDO and a cytotoxic drug, staining was significantly increased, indicating the presence of senescence ... culture of CDO with any cytotoxic drug resulted in further increases in SA-b-gal staining that were significantly greater than those seen in cells cultured with SO and drug (all P < 0.001), indicating ... significantly increased in GEO cells treated with the combination of CDO and 5-FU (Fig 6A) In both HCT116 and GEO cells, there were no significant changes in the levels of CDK 4, cyclin D or CDK in response...
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Báo cáo khoa học:

Báo cáo khoa học: "Effects of propranolol in combination with radiation on apoptosis and survival of gastric cancer cells in vitro" ppsx

Báo cáo khoa học

... of Figure Apoptosis induction by isoproterenol or propranolol in combination with irradiation in BGC-823 and SGC-7901 cells There was an increasing rate of apoptosis in gastric cancer cell lines ... (OS) in resected adenocarcinoma of the stomach and gastroesophageal junction: Update of the results of Intergroup Study INT-0116 (SWOG 9008) Gastrointestinal Cancers Symposium 2004, Abstract Sminia ... shown in Figure A significant difference in the colony forming rate was found in combination with irradiation and propranolol at 50 μmol/L in SGC-7901 and BGC823 cells (p < 0.01) compared with...
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In vitro and in vivo study of ABT 869 in treatment acute myeloid leukemia (AML) alone or in combination with chemotherapy or HDAC inhibitors  insight into molecular mechanism and biologic characterization

In vitro and in vivo study of ABT 869 in treatment acute myeloid leukemia (AML) alone or in combination with chemotherapy or HDAC inhibitors insight into molecular mechanism and biologic characterization

Cao đẳng - Đại học

... Phosphoinositide 3-kinase Promyelocytic Leukemia Zinc Finger protein Phosphatase of Regenerating Liver Retinoblastoma Protein Red Fluorescence Protein RNA interference Receptor Tyrosine Kinase ... values obtained for ABT-869 in combination with Ara-C and Dox employing three sequences are shown in Table To determine whether the combination therapy produce synergism in induction of apoptosis, ... RPMI1640 (Invitrogen, Carlsbad, CA) with 10% of fetal bovine serum (FBS, JRH Bioscience Inc, Lenexa, KS) Cells were maintained in density of x 105 to 10x105 cells/ml in a humid incubator with 5%...
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Economic growth, International trade, government expenditure versus corruption, and other determinants of income inequality in countries with different income levels

Economic growth, International trade, government expenditure versus corruption, and other determinants of income inequality in countries with different income levels

Tổng hợp

... effect of 1% increase in GDP per 24 capita in LA and South and East Asia was 0.206 and 0.158% increase of Gini index correspondingly Education, being insignificant in most of the countries including ... point starts to decline iv Chapter INTRODUCTION Income inequality dynamics differ a lot across countries, but the sharp rise of inequality in some of them has made income distribution one of ... and disrgarding the size of the countries, inequality between countries using GDI per capita but taking into account the size of countries and ignoring inequality within countries and inequality...
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Báo cáo y học:

Báo cáo y học: "Effects of p-Synephrine alone and in Combination with Selected Bioflavonoids on Resting Metabolism, Blood Pressure, Heart Rate and Self-Reported Mood Changes"

Y học thưởng thức

... data indicate that increasing the hesperidin from 100 mg to 1,000 mg reversed some of the thermogenic effects of 100 mg hesperidin in combination with 50 mg p-synephrine plus 600 mg naringin It ... This increase in thermogenesis is similar to the increases reported in previous studies involving p-synephrine [17, 18] The increase in RMR between Group 4, the combination of p-synephrine with ... observed in response to p-synephrine or p-synephrine in combination with naringin and hesperidin (Table 2) p-Synephrine differs from ephedrine in that it has a hydroxyl group on the para position of...
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Children’s Health Deficits due to Diarrhoea: Effects of Water Supply and Sanitation Systems in Slums with Different Water Logging Conditions

Children’s Health Deficits due to Diarrhoea: Effects of Water Supply and Sanitation Systems in Slums with Different Water Logging Conditions

Môi trường

... Households with children defecating in open field Households with children defecating in room Households with children defecating in verandah Households with children defecating in latrine   defecating ... defecating in room Households with children defecating in verandah Households with children defecating in latrine Hygiene practices Hand washing with soap before eating Hand washing without soap ... NCD Hand washing with soap before eating Hand washing without soap before eating No hand washing before eating Hand washing after defecation with soap Hand washing after defecation without soap...
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Báo cáo

Báo cáo " Development of climate change scenarios for small areas in Vietnam by using the MAGICC/SCENGEN software in combination with statistic correction" docx

Báo cáo khoa học

... value in increasing level, followed by Quy Nhon and Can Tho This is quite compatible with the temperature happening in the past (increasing level declined southwards) In addition, temperatures in ... Assumption testing the magnitude of the correlation coefficient Rxy + Assumption testing the magnitude of the coefficient of regression equation + Assumption testing the efficiency of regression ... are often June to August in all three cities with 1.7 - 2.9 oC in Da Nang, 1.5-2.6 oC in Quy Nhon and 1.4-2.5 o C in Can Tho 3.2 Rainfall scenarios Rainfall scenarios show that rainfall in dry...
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Báo cáo hóa học:

Báo cáo hóa học: "High activity of sequential low dose chemo-modulating Temozolomide in combination with Fotemustine in metastatic melanoma. A feasibility study" pptx

Hóa học - Dầu khí

... Other minor side effects included nausea-vomiting involving about 50% of patient in both cohorts, transaminase increase in patient in cohort A, and asthenia in patient in cohort B The median of delivered ... necessary in patients in cohort A and in patients of cohort B due to severe thrombocytopenia Chemotherapy was also delayed in patients of cohort A and in patients of cohort B because of failure of hematologic ... arising in the metastatic lesion without evidence of disease progression Interestingly, one PR in cohort B, occurred in a female with a disseminated disease involving axillaries lymph nodes, diffuse...
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Báo cáo hóa học:

Báo cáo hóa học: "Dermal absorption of aromatic amines in workers with different skin lesions: a report on 4 cases" doc

Hóa học - Dầu khí

... internal to external exposure Additionally we assessed the influence of smoking on internal exposure by measurement of cotinine in the urine of the workers In view of the explanatory nature of ... Worker no Worker no Worker no Worker no Skin condition of hands o-Toluidine in the air (µg/m3) o-Toluidine in urine (µg/l) Cotinine in urine (µg/l) Healthy skin 58.29 74.83 4471 µg/L (= smoker) Mild ... Drexler H, Korinth G: Penetration of β-naphthylamine and o-toluidine through human skin in vitro Arch Toxicol in press 2006, Apr Korinth G, Geh S, Schaller KH, Drexler H: In vitro evaluation of the...
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báo cáo hóa học:

báo cáo hóa học:" Effects of TGF-β1 and IGF-1 on proliferation of human nucleus pulposus cells in medium with different serum concentrations" pptx

Hóa học - Dầu khí

... for individuals in the early stage of degeneration found by MRI examination[16] An[17] reported that the intradiscal administration of osteogenic protein-1 by injection in vivo resulted in an increased ... [6,7] To investigate the therapeutic potential in the treatment of disc degeneration, we investigated the effects of TGF-β1 and IGF-1 on the proliferation of human NP cells in single or combination ... However, cell viability showed a trend of decreasing in response to further elevation of the concentrations Time-course effect of growth factors in single or combinations The optical density was assessed...
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Báo cáo lâm nghiệp:

Báo cáo lâm nghiệp: "Germination response of alder and birch seeds to applied gibberellic acid and priming treatments in combination with chilling" ppt

Báo cáo khoa học

... periods without the risk of premature germination [9, 10] A combination of GA3 and chilling at TMC levels might increase germination potential while reducing the risk of premature germination in alder ... Percentage germination, including or excluding premature germination, in fully imbibed alder and birch seeds in response to chilling and priming Chilling duration (weeks) 18 Premature germination included ... during chilling on dormancy release in FI and TMC seeds of alder and birch In addition, the effect of priming at 15 ◦ C with or without PEG on the germination response of FI and TMC seeds without...
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Báo cáo y học:

Báo cáo y học: "Deactivation of endothelium and reduction in angiogenesis in psoriatic skin and synovium by low dose infliximab therapy in combination with stable methotrexate therapy: a prospective single-centre study" ppt

Báo cáo khoa học

... symptoms of both psoriasis and PsA In comparison with previously performed clinical trials in PsA with mg/kg infliximab [33], we demonstrated that a low-dose treatment regimen with mg/kg in combination ... that after weeks of infliximab therapy a beneficial clinical effect can be observed in both skin lesions and inflamed joints in PsA In addition, we recently showed in patients with rheumatoid ... Representative images of immunohistochemical staining are shown in Fig Discussion The results of the present study confirm that anti-TNF-α treatment with infliximab is effective in reducing clinical signs...
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báo cáo khoa học:

báo cáo khoa học: "Aspergilloma in combination with adenocarcinoma of the lung" ppt

Báo cáo khoa học

... wall of the cavity and its position is not altered with the patient’s movements [5] and particularly in case of preexisting factor of lung cancer Frozen section examination of a Wedge excision of ... found in healthy persons with no risk factors, lung cancer must be ruled out by frozen section of a pulmonary excision of aspergilloma If combination is confirmed, a carcinologic surgery with ... H: Aspergilloma in combination with adenocarcinoma of the lung Can J Surg 2008, 51(1) Bardana EJ: Pulmonary aspergillosis In Aspergillosis Edited by: Al-Doory Y, Wagner GE Springfield (IL): Charles...
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Báo cáo khoa học:

Báo cáo khoa học: "Acute toxicity of second generation HIV protease-inhibitors in combination with radiotherapy: a retrospective case series" pptx

Báo cáo khoa học

... safety of radiation therapy combined with the newer generation of PIs in treatment of non-AIDS defining malignancies which are increasingly common in the era of improved ART The series included ... valuable information about the acute toxicity of combining radiation with current PI therapies Review of this contemporary series of patients did not find an increase in acute toxicity from the combination ... histologies, including HIV-defining (0 with PIs; [23%] without PIs), HIV-associated (11 [58%] with PIs; [38%] without PIs), non-HIV-associated malignancies (8 [42%] with PIs, [38%] without PIs),...
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Báo cáo khoa học:

Báo cáo khoa học: "A phase I radiation dose-escalation study to determine the maximal dose of radiotherapy in combination with weekly gemcitabine in patients with locally advanced pancreatic adenocarcinoma" doc

Báo cáo khoa học

... where the investigators also combined a fixed weekly dose of gemcitabine (1000 mg/m2) with an escalating dose of RT [20] Escalation was achieved by increasing the fraction size in increments of 0.2 ... (G) was administered on day of week 1, 2, 3, and in a single dose of 300 mg/m2 as a 30-min IV infusion at least one hour prior to RT; the starting dose of RT was 45 Gy in 25 fractions of 1.8 Gy ... considerations The study intent was to determinate the DLT of escalating doses of RT delivered concurrently with a fixed dose of gemcitabine (300 mg/m2) administered on a weekly basis within the same overall...
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Báo cáo khoa học:

Báo cáo khoa học: " The effect on the small bowel of 5-FU and oxaliplatin in combination with radiation using a microcolony survival assay" pptx

Báo cáo khoa học

... alone, or in combination with equitoxic single doses of 5-FU, oxaliplatin, or both drugs The same single doses of 5-FU and oxaliplatin were combined with split dose radiation Results A total of 265 ... oxaliplatin Both drugs were administered intraperitoneally Single doses of 5-FU (Mayne Pharma) 0-200 mg/kg and of oxaliplatin (Mayne Pharma) 0-10 mg/kg were administered alone or in combination with ... although again with large error bars at this dose level http://www.ro-journal.com/content/4/1/61 Increasing doses of oxaliplatin resulted in an essentially linear decrease in the number of surviving...
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báo cáo khoa học:

báo cáo khoa học: "Phase 2 study of canfosfamide in combination with pegylated liposomal doxorubicin in platinum and paclitaxel refractory or resistant epithelial ovarian cancer" docx

Báo cáo khoa học

... cytotoxicity in vitro of a variety of chemotherapeutic agents with different modes of action, including carboplatin, doxorubicin, paclitaxel, and gemcitabine [19] In addition to its favorable preclinical ... protein kinase (MAPK) signaling protein, mitogen activated protein kinase kinase (MKK4), in canfosfamide treated cells, as well as the activation of jun-N-terminal kinase (JNK), p38 MAP kinase ... the combination There were no dose limiting toxicities (DLTs) The MTD was full doses of both agents Full doses of canfosfamide in combination with PLD were administered in 88.4% and 87.3% of cycles,...
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Báo cáo y học:

Báo cáo y học: "Alterations in the muscle-to-capillary interface in patients with different degrees of chronic obstructive pulmonary disease" pps

Báo cáo khoa học

... proportion of type I fibres in the tibialis anterior muscle of patients with COPD [10] This is in line with previous studies [3,7-9] and together with previous findings of a decrease in oxidative ... activities in COPD [6,7] our findings indicate the occurrence of a shift towards a more glycolytic profile in the limb muscle of COPD patients Furthermore, the number of capillaries around a single ... capacity determined by the 6-min walking test In the Page of context of motor unit recruitment during different muscular activities it is known that low intensity muscle activities mainly recruit...
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Báo cáo y học:

Báo cáo y học: " Maximal respiratory static pressures in patients with different stages of COPD severity" potx

Báo cáo khoa học

... steroid-induced myopathy; d) pulmonary hyperinflation with increased residual volume; e) reduced blood flow to the respiratory muscles [13-19] The measurement of MIP and MEP is indicated in any of ... pressures and functional parameters at different stages of COPD Methods During year 110 patients suffering from COPD were enrolled in this study All patients were in a clinically stable condition and ... examination, we excluded those patients whose FEV1 improvement, after a bronchodilatory test, was ≥ 12% and 200 mL of the baseline value and with a history of asthma Other patients, with clinically...
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Báo cáo y học:

Báo cáo y học: ""Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence" doc

Báo cáo khoa học

... replication in U1 and ACH-2 cells, and toxicity in uninfected JurPotencies Potencies of different HDACIs in terms of activation of HIV-1 replication in U1 and ACH-2 cells, and toxicity in uninfected ... largely disappointing so far Valproic acid, a relatively weak HDACI, was tested in a small clinical trial in combination with antiretroviral therapy intensified with the fusion inhibitor enfuvirtide ... HDACIs capable of activating HIV-1, we first tested the HIV-1 activating ability of our institutional library of HDACIs [see Additional file 1] in cell lines in which HIV-1 is inducible (i.e...
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