in section 8 1 the results from the social network analysis sna as well as the qualitative data analysis from the interviews are used to draw out conc
Quantification of epidermal growth factor receptor dynamics and interactions in living cells by fluorescent correlation and cross correlation spectroscopy
... and cytoskeleton will be in section 1. 1.4 - 1. 1 .8, respectively 1. 1 .1 The importance and clinical trials There are ligands known to bind to EGFR, including EGF, transforming growth factorα (TGF- ... distance from the centre of the laser focus to where the intensity has decay to 1/ e2 Axial distance from the centre of the laser focus to where the intensity has decay to 1/ e2 Autocorrelation ... comparing different results from various research groups 1. 1 .8 EGFR and the cytoskeleton 1. 1 .8. 1 Cytoskeleton Besides rafts, another major constraint of molecule diffusion on the membrane is caused...
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Báo cáo y học: " Helicobacter pylori induces mitochondrial DNA mutation and reactive oxygen species level in AGS cells"
... control 14 15 14 7 Negative con- 1 484 16 6 trol Positive con- 773 82 trol 11 638M 80 7 86 11 6 38 750 82 a Duration (h) 12 24 1 482 15 3 14 27 16 2 15 64 16 4 14 74 13 9 15 71 17 2 13 78 1 48 16 23 17 5 15 68 15 1 81 6±93 84 8 80 ... 13 98 14 3 15 92 1 78 13 47 1 28 Negative 13 79 15 6 14 52 16 7 13 68 12 3 16 76± 18 5 1 383 14 9 control Positive 81 5 88 7 58 79 81 8 85 692±69 795± 71 control Hp 116 38M 6 58 62 586 ±54 415 ±37 303±35 18 6 ± 21 Hp 116 38 503±54a ... 350±42b 282 ±31c 15 3 17 d 10 2 12 e Hp 116 38 70 Hp 116 38M Cytochrome C reduction 60 50 40 30 Note: P
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Báo cáo khoa học: Insulin induces heme oxygenase-1 through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in renal cells pptx
... epithelial cells Insulininduced HO -1 protein expression was sensitive to PI3K ⁄ Akt inhibition and Nrf2 gene silencing The fold-increase in both HO -1 protein and mRNA in response to insulin was ... as a loading control As previously, antibody to HO -1 was used, with b-actin as loading control Nrf2 translocates to the nucleus following insulin treatment In ACHN cells treated with increasing ... factors that may be involved in mediating the effect of insulin on HO -1 expression, including heat shock transcription factor -1 (HSF -1) , hypoxia-inducible factor -1 (HIF -1) and NF-E2-related factor...
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Báo cáo khoa học: Membrane trafficking of CD98 and its ligand galectin 3 in BeWo cells ) implication for placental cell fusion pot
... increase in CD 98 expression This stimulation increased almost linearly up to 48 h, at which time there was approximately 35% more CD 98 in BeWo cells cultured in forskolin-containing medium than in ... co-localization of these two molecules in the plasma membrane, in the cytoplasm and in the nucleus of forskolin-treated BeWo cells Inhibition of galectin binding to membrane glycoproteins affects cellular ... acts as a receptor for ligands containing poly(N-acetyllactosamine) sequences through the C-terminus CRD We used the high affinity of galectin for lactose (Lac) to inhibit binding between the glycosylated...
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Báo cáo khoa học: A peptide derived from cyclin-dependent kinase activator (p35) specifically inhibits Cdk5 activity and phosphorylation of tau protein in transfected cells pdf
... CIP Thus the increased flexibility of CIP relative to the p16 structure may allow these residues to conform more closely to the contours of the Cdk5 interaction site without inducing the T-loop ... activator and, when removed, transform CIP into a high affinity inhibitor are also the segments that normally link together the N- and C-terminal ends of the activating domain of p35 and confer the ... existence of cyclin fold in neuronal Cdk5a activator J Biol Chem 272, 12 3 18 12 327 18 Morgan, D.O (19 95) Principles of CDK regulation Nature 374, 13 1 13 4 19 Sharma, P., Sharma, M., Amin, N.D., Albers,...
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báo cáo hóa học:" Activation of PKA, p38 MAPK and ERK1/2 by gonadotropins in cumulus cells is critical for induction of EGF-like factor and TACE/ ADAM17 gene expression during in vitro maturation of porcine COCs" doc
... maturation In this study, to clarify the intracellular pathway involved in EGF-like factor and Tace/Adam17 expression in cumulus cells, we examined the effect of PKA inhibitor (H89), p 38 MAPK inhibitor ... carcinoma Cancer Res 2006, 66 :1 18 3 1- 1 18 3 9 Richards JS: New signaling pathways for hormones and cyclic adenisine 3', 5'-monophosphate action in endocrine cells Mol Endocrinol 20 01, 15 :2009-20 18 ... ERK1/2 was detected The addition of H89 or SB20 580 to the medium significantly decreased the intensity of bands as compared with those in cumulus cells of COCs cultured without any inhibitor,...
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Báo cáo toán học: "Expression and function of micro RNAs in immune cells during normal or disease state" pptx
... Conflict of interest The authors have declared that no conflict of interest exists References 10 11 12 13 14 15 16 17 18 19 20 Ambros V The functions of animal microRNAs Nature 2004; 4 31: 350–355 ... miR -15 5 76 miR- 18 1 miR- 18 1 is highly expressed in the thymus as well as the brain, lung, bone marrow and spleen [9, 10 ] This miRNA has been shown to regulate T and B cell development when ectopically ... the progenitor cells are not shown and only four of the main hematopoitic lineages are depicted miRNAs that are reported to be involved in the differentiation of the shown lineages based on the...
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Báo cáo y học: " Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq" docx
... 0 0 0 3 3 3 3 1 1 1 1 1 1 1 1 1 0 0 0 0 0 0 0 0 0 3 3 3 3 1 1 1 1 2 2 2 2 0 0 0 0 0 1 1 1 1 3 3 3 3 2 2 2 1 1 1 1 3 3 3 3 G T T T A C T T 717 5432 C G C T G 1 1 1 1 1 1 1 1 1 1 1 3 3 3 3 3 3 3 ... A A 1 0 0 0 1 0 0 0 0 2 1 2 2 2 2 2 2 3 0 2 2 2 0 0 1 1 1 0 0 0 3 1 2 0 0 0 1 3 2 1 3 1 1 3 1 2 0 0 1 3 2 1 0 0 0 0 2 0 0 0 0 1 1 1 1 3 3 3 3 1 1 3 3 1 1 1 1 1 1 0 0 2 0 3 2 0 0 0 0 3 1 1 0 0 ... 2 ,84 9 (7%) 2,560 (6%) 2, 18 1 (5%) 41, 780 353 (b) Motallebipour et al R129.3 716 343 716 326 709 1 78 696 16 5 6 91 162 666 16 1 659 16 1 397 15 6 18 9 15 5 We detected 8, 17 5 peaks for FOXA1 and 4,598...
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Some suggested activities for teaching and learning the writing sections in the textbook english 10
... 2 .1 Teaching Writing .9 2 .1. 1 Writing and the Roles of Writing 2 .1. 2 Approaches to Teaching Writing 11 2 .1. 3 The Stages of Teaching Writing 15 2 .1. 4 Principles ... are: • introducing the writing topic to stimulate interest • doing the pre-writing stage of the process of writing • working with the model • presenting key words related to the topic • outlining ... to prepare pictures as well as to conduct it in class The findings also reveals that in reality, teachers often ask their students to the writing tasks given in the textbook without making any...
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Slide an investigation into some approaches to vocabulary teaching and learning and the application of games in teaching and learning vocabulary at pre – intermediate level at foreign language center – haiphong university
... of words 1. 1.3 Words and their meanings 1. 1.4 Words use 1. 1.5 Form of words 1. 2 Vocabulary in language teaching and learning 1. 2 .1 A neglect aspect of foreign language methodology 1. 2.2 Ineffective ... review 1. 1 Vocabulary 1. 2 Vocabulary in language teaching and learning 1. 3 Approaches to language teaching and their relevance to vocabulary 1. 4 Recent research about teaching and learning second ... vocabulary 1. 5 Advantages of the use of games in vocabulary teaching and learning Part two: Development Chapter one: Literature review 1. 1 Vocabulary 1. 1 .1 Definition of Vocabulary 1. 1.2 Concept...
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Noun phrases in some selected chapters from “pride and prejudice” by jane austen and the equivalents in the translated version in vietnamese
... clear in terms of the nouns they refer to owing to this way of translation as the translator has taken the question who his target readers are into consideration In 11 0b and 11 1b., two connectors ... Only in one or two cases are they referred to for the purpose of emphasis As far as definite article the is taken into account, the translator transfers the notion of being definite brought about ... during her lifetime: Sense and Sensibility ( 18 1 1) , Pride and Prejudice ( 18 1 3), Mansfield Park ( 18 1 4), Emma ( 18 1 5) Two novels, Northanger Abbey and Persuasion were published posthumously in 18 1 7...
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Tài liệu Báo cáo " Occurrences of microcystis spp. and microcystins in some cyanobacterial blooms in freshwater bodies in Vietnam " docx
... 66 312 10 13 15 1 13 1 16 0,5 16 0 ,8 4,5 10 0 11 10 ,5 0,5 3,7 96 ,8 14 0,5 0 0 14 4 11 29,7 2 78, 6 213 ,5 624,5 M protocystis 700000 M panniformis 600000 M flos-aquae 500000 c ells/m L of 312 x103 cells/ ... Fig.2) Only the concentration of toxin in Lake Tri An was too low to detect The toxin concentrations ranged from 17 .966 ng/mL in Duc An to 5 .85 4 ng/mL in Nhu Y sample Table Microcystins detection ... 624,5 207,2 23 Microcystins concentrations (ng/ mL) 9.434 17 .966 17 .579 14 .9 68 5 .85 4 13 . 012 16 .395 700000 20 18 16 14 12 10 cells/mL 600000 500000 400000 300000 200000 10 0000 m Ho an M Ki e un...
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Tài liệu Báo cáo " Effect of Sweet potato (Ipomoea batatas (L.) Lam) leaf extract on hypoglycaemia, blood insulin secretion, and key carbohydrate metabolic enzymes in expermentally obese and STZ-induced diabetic mice " pptx
... 3 .83 2 18 . 16 ± 13 .63 32.37±3. 51 5.47±0.35 HFD 14 .63 ± 1. 52* 53. 21 ± 4.62* 19 6.03 ± 10 .36* 18 3 .59 ±7.36* 1 38. 12 ± 6. 21* 485 .12 ± 17 . 71 21. 16±2.53* 9.42±0.37 Change,% ↑2.23 ↑ 61. 93 86 .45 ↑99 .19 15 4. 18 ... 2 58. 13 ± 15 .23 16 7. 31 ± 14 .11 ↓35. 18 TG (mg/dl) 642 .86 ± 10 .42 455.35 ± 9.6 ↓29 .17 HDL-c (mg/dL) 13 .57 ± 2.73 20.53 ± 1. 52 ↑ 51. 28 LDL-c (mg/dL) 11 5.00 ± 7. 61 55. 71 ± 6 .17 ↓ 51. 55 3.5 Effect of ... STZ is the toxin from Actinomycetes (Streptomyces chromogen) It was used to induce experimentally diabetic models of animals [4,5,7] The injection of single dose of STZ (12 0mg kg -1) into the HFD...
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Tài liệu Báo cáo khoa học: Staphylococcal enterotoxin C1-induced pyrogenic cytokine production in human peripheral blood mononuclear cells is mediated by NADPH oxidase and nuclear factor-kappa B doc
... 387 00 Fever index (°C) ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± 510 * 210 10 0 260 90 960 26 87 0 93 86 0 10 0 87 0 2 0. 18 1. 06 0. 21 0.32 0 .11 0. 31 0.22 1. 19 0 .13 1. 12 0 .11 1. 07 0.22 1. 08 0. 21 0.25 ± ± ± ... chemiluminescence counts 10 12 680 16 223 689 312 135 457 014 464427 496952 584 833 ± ± ± ± ± ± ± 1 18 7 18 0 61* 279 18 * 52 511 * 44959* 36740* 30245* Discussion The present study demonstrates that the febrile ... vehicle group Cytokine production (pgÆmL )1) Time (h) Treatment IL-1b Vehicle SEC1 Vehicle SEC1 Vehicle SEC1 Vehicle SEC1 Vehicle SEC1 Vehicle SEC1 12 6 91 1725 13 217 9 3 011 3 18 7 30 91 12 24 48 72 96 Table...
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Tài liệu Báo cáo Y học: The b-1,4-endogalactanase A gene from Aspergillus niger is specifically induced on arabinose and galacturonic acid and plays an important role in the degradation of pectic hairy regions pdf
... time was 200 nsec, the accelerating voltage was 12 000 V, the grid voltage was 7200 V and the guide wire voltage was 9.6 V The instrument was used in the reflector mode The mass spectrometer was ... 15 min, 30 min, h and 20 h, respectively The incubation was stopped by heating the samples for at 10 0 °C a-L -1, 3-Arabinofuranosidase activity in the GALA preparation was measured as described ... and Pseudomonas fluorescens [11 ] (Fig 1) Both catalytic residues identified in P fluorescens (E1 61, E270) [11 ] are present in the eukaryotic b -1, 4-endogalactanases Sequence analysis of the promoter...
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Báo cáo khoa học: Muramyl-dipeptide-induced mitochondrial proton leak in macrophages is associated with upregulation of uncoupling protein 2 and the production of reactive oxygen and reactive nitrogen species docx
... rate B 10 0 10 1 PI 10 2 10 3 A 10 4 MB (10 0 lgÆmL )1) 10 0 ± 11 2 ± 14 .2 10 7 ± 10 .8 95. 68 ± 4.6 LPS (1 lgÆmL )1) 10 0 ± 1. 5 10 2 ± 12 .3 98 ± 7.6 98. 27 ± 8. 2 10 0 10 1 10 2 10 3 Annex-FITC 10 4 10 0 10 1 10 2 10 3 ... final concentration of 10 6 cellsÆmL )1 in 1 binding buffer (10 · binding buffer contains 0 .1 m HEPES ⁄ NaOH (pH 7.4), 1. 4 m NaCl, 25 mm CaCl2) The solution (10 0 lL, · 10 5 cells) was transferred to ... versus non-toxic analogues such as MB The decrease in RCR in mitochondria of MDP-treated mice is attributed to an increase in mitochondrial proton leak (i.e mitochondrial uncoupling) In the present...
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Báo cáo Y học: Concerted regulation of free arachidonic acid and hormone-induced steroid synthesis by acyl-CoA thioesterases and acyl-CoA synthetases in adrenal cells pdf
... 269) 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 intramitochondrial cholesterol translocator J Biol Chem 262, 9 18 1 –9 18 8 Miller, W.L (1 988 ) Gene conversions, deletions and polymorphisms in congenital ... binding to the reduced form (Fe2+) of the enzyme thereby keeping it inactive [49] In our experiments NDGA was effective in inhibiting the activity of purified recombinant MTE-I in an in vitro assay ... triacsin C, an inhibitor of the AA-CoA synthetase Our results are consistent with the involvement of an acyl-CoA synthetase and an acyl-CoA thioesterase as important regulators of AA release in the...
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Báo cáo khóa học: Phospholipase C, protein kinase C, Ca 2+ /calmodulin-dependent protein kinase II, and redox state are involved in epigallocatechin gallate-induced phospholipase D activation in human astroglioma cells ppt
... examined the effects of pertussis toxin and the phosphoinositide-specific PLC inhibitor, U-7 312 2 Pretreatment with pertussis toxin (10 0 ngÆmL )1 for 24 h) inhibited sphingosine 1- phosphate-induced ... phospholipase D by EGCG (Eur J Biochem 2 71) 3479 increase in [Ca2+]i The EGCG-evoked increase in [Ca2+]i was inhibited by the nonspecific Ca2+ channel inhibitor lanthanum, and the PLC inhibitor U7 312 2, ... Res 21, 2633–2642 11 Min, D.S., Kim, E.G & Exton, J.H (19 98) Involvement of tyrosine phosphorylation and protein kinase C in the activation of phospholipase D by H2O2 in Swiss 3T3 fibroblasts...
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Báo cáo khoa học: Expression of heme oxygenase-1 is repressed by interferon-c and induced by hypoxia in human retinal pigment epithelial cells pot
... (Tokyo) 12 1, 11 62 11 68 14 Hara, E., Takahashi, K., Takeda, K., Nakayama, M., Yoshizawa, M., Fujita, H., Shirato, K & Shibahara, S (19 99) Induction of heme oxygenase -1 gene as a response in sensing the ... any combination with interferon-c decreased the HO -1 mRNA levels and increased Bach1 mRNA levels (Fig 1B) Notably, the combination of TNF-a and IL-1b caused the concomitant induction of HO -1 and ... actinomycin D (1 lgÆmL )1) Other conditions are the same as in Fig The data shown are from one of three independent experiments with similar results (B) Relative expression levels of HO -1 mRNA The...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008