... This increase in thermogenesis is similar to the increases reported in previous studies involving p-synephrine [17, 18] The increase in RMR between Group 4, the combination of p-synephrine with ... blood pressure were observed in response to p-synephrine or p-synephrine incombinationwith naringin and hesperidin (Table 2) p-Synephrine differs from ephedrine in that it has a hydroxyl group ... p-synephrine) Group 3: Advantra Z® with mg hesperidin and 600 mg naringin Group 4: Advantra Z® with 100 mg hesperidin and 600 mg naringin Group 5: Advantra Z® with 1,000 mg hesperidin and 600 mg naringin...
... syndrome (MDS) [7] In order to eradicate minimum residual CML cells which survived long-term imatinib therapy, we started WT1 peptide vaccination therapy incombinationwith imatinib in a CML patient ... suppressing the function of regulatory T cells incombinationwith anti-tumor immunotherapy including tumor antigen peptide vaccination The present study showed that WT1 peptide vaccination for imatinib-pretreated ... reported a clinical y trial using a combi ination of PR peptides ( R1 (peptides derived from prote einase 3) and WT1 peptide in paes tients with myeloid malignancies including AML in d comple...
... value in increasing level, followed by Quy Nhon and Can Tho This is quite compatible with the temperature happening in the past (increasing level declined southwards) In addition, temperatures in ... June to August in all three cities with 1.7 - 2.9 oC in Da Nang, 1.5-2.6 oC in Quy Nhon and 1.4-2.5 o C in Can Tho 3.2 Rainfall scenarios Rainfall scenarios show that rainfall in dry season can ... annual rainfall can increase about 5-9% in Da Nang, 2– 4% in Quy Nhon and 2% in Can Tho In dry season, the months with the highest decrease are from March to May with 5-10% of decrease in Da Nang,...
... combining CDO with cytotoxic agents in HCT116 and GEO cells Cells were cultured with CDO (C) alone or incombinationwith 5-FU, SN38 or VP16 There were significant reductions in cell number in ... containing 10 lM BrdU for 30 mins before fixing with ice-cold 70% (v/v) ethanol and permeabilization in M HCl with 0.5% (v/v) Triton X-100 Samples were washed and incubated with fluorescein isothiocyanate-conjugated ... chemotherapy Indeed, it has been shown that a palindromic trioctamer of this sequence can interfere with CREB binding, and specifically inhibit PKA subunit expression, interfering with the CRE-PKA...
... binding of SOX10 and Sp1 proteins to the GC1 ⁄ CA2, but were unable to detect the complexes, containing both SOX10 and Sp1 proteins (data not shown) It is conceivable that the in vitro binding ... simultaneous binding of the two proteins to the GC1 ⁄ CA2 SOX10 and Sp1 bind to the EDNRB promoter in vivo To investigate whether SOX10 and ⁄ or Sp1 bind to the EDNRB gene in vivo, chromatin immunoprecipitaion ... end-labeled with [c-32P] ATP and used as probes The SOX10-containing lysates were preincubated for 30 on ice with or without a competitor in the absence of a probe and then incubated with the probe...
... tumors in mice including the use of Toll-like receptor agonists incombinationwith anti-CD137 [19] It would be of interest to determine if coadministration of cytokine can enhance therapy against ... immunosuppressive cytokines Another potential reason may lie in inherent differences in lymph nodes draining subcutaneous sites and those draining internal sites In any event, coadministration of IL-2 ... alternate cytokines can be used with benefit incombination immunotherapies, including IL-15 [23] and IL-21 [15] Since IL-2 can be associated with toxicity, it would be of interest to determine if these...
... respectively) Other minor side effects included nausea-vomiting involving about 50% of patient in both cohorts, transaminase increase in patient in cohort A, and asthenia in patient in cohort B The ... dacarbazine in patients with metastatic melanoma J Clin Oncol 1999, 17:2745-2761 Ridolfi R, Sileni VC, Guida M, et al: Cisplatin, Dacarbazine with or without Subcutaneous Interleukin-2 and Alfa Interferon ... interferon-alpha2b, interleukin-2 and fotemustine for patients with metastatic melanoma Melanoma Res 2000, 10(5):475-82 Avril MF, Armadal S, Grab JJ, et al: Fotemustine compared with Dacarbazine in patients with...
... Percentage germination, including or excluding premature germination, in fully imbibed alder and birch seeds in response to chilling and priming Chilling duration (weeks) 18 Premature germination included ... was similar in both species, with chilling and GA3 treatment having a larger effect in birch than in alder Germination was particularly low in birch seeds that received 30 days chilling without GA3 ... periods without the risk of premature germination [9, 10] A combination of GA3 and chilling at TMC levels might increase germination potential while reducing the risk of premature germination in alder...
... anti-TNF-α treatment with infliximab is effective in reducing clinical signs and symptoms of both psoriasis and PsA In comparison with previously performed clinical trials in PsA with mg/kg infliximab ... vascularity, in both psoriatic lesional skin and PsA synovial tissue, in relationship to the clinical effects In short, we found that lowdose infliximab treatment incombinationwith stable methotrexate ... effects of infliximab It is known from clinical experience that after weeks of infliximab therapy a beneficial clinical effect can be observed in both skin lesions and inflamed joints in PsA In addition,...
... Written informed consent was obtained from the patient for publication of this case report and accompanying References Saleh W, Ostry A, Henteleff H: Aspergilloma incombinationwith adenocarcinoma ... and interpretation of the data AA gave final approval for publication All authors read and approved the final manuscript Competing interests The authors declare that they have no competing interests ... persons with no risk factors, lung cancer must be ruled out by frozen section of a pulmonary excision of aspergilloma If combination is confirmed, a carcinologic surgery with mediastinal lymph...
... Apoptosis induction by isoproterenol or propranolol incombinationwith irradiation in BGC-823 and SGC-7901 cells There was an increasing rate of apoptosis in gastric cancer cell lines in response ... colonies, suggesting that there was radiosensitization in the SGC-7901 and BGC-823 cell lines In addition, propranolol showed a synergism of growth inhibition incombinationwith irradiation in SGC-7901 ... NY) containing 10% (v/v) heat-inactivated fetal bovine serum (Gibco, Grand Island, NY), penicillin (100 U/mL) and streptomycin (100 mg/mL), and they were maintained in a 37°C humidified incubator...
... treatment delivered (21 with PIs, 13 without PIs) for a variety of histologies, including HIV-defining (0 with PIs; [23%] without PIs), HIV-associated (11 [58%] with PIs; [38%] without PIs), non-HIV-associated ... radiation therapy combined with the newer generation of PIs in treatment of non-AIDS defining malignancies which are increasingly common in the era of improved ART The series included only patients ... (19 with PIs, 13 without PIs), 13 included systemic chemotherapy regimens (7 [37%] with PIs; [46%] without PIs) 21 of the 29 patients were receiving HIV medications (17 [94%] with PIs; [36%] without...
... full-dose gemcitabine in patients with advanced pancreatic cancer J Clin Oncol 2001, 19:4202-4208 McGinn CJ, Smith DC, Szarka CE: A phase I study of gemcitabine (GEM) incombinationwith radiation ... anti-tumour activity [13,15,16] In a phase I study by McGinn et al to find the MTD of gemcitabine in association with RT to 50.4 Gy in 1.8 Gy daily fractions in patients with locally advanced nonresectable ... achieved by increasing the fraction size in increments of 0.2 Gy, keeping the duration of radiation constant at weeks The starting dose was 30 Gy (in Gy fractions) and the final dose investigated...
... 10 Gy, were given alone, or incombinationwith equitoxic single doses of 5-FU, oxaliplatin, or both drugs The same single doses of 5-FU and oxaliplatin were combined with split dose radiation ... intraperitoneally Single doses of 5-FU (Mayne Pharma) 0-200 mg/kg and of oxaliplatin (Mayne Pharma) 0-10 mg/kg were administered alone or incombinationwith radiotherapy When combined, 5-FU was injected ... was studied at single doses ranging from - 17 Gy, with the purpose of describing the dose-response relations in our experimental setting and finding appropriate doses for the combined treatment...
... clinical activity incombinationwith PLD in platinum resistant ovarian cancer Canfosfamide has shown single-agent activity in heavily pretreated platinum resistant ovarian cancer patients with ... trial (ASSIST-3) with canfosfamide incombinationwith carboplatin versus PLD as second-line therapy in platinum resistant OC was presented [33] In this study, the primary endpoint was ORR and ... (Telcyta™, a novel glutathione analog) incombinationwith carboplatin in platinum refractory or resistant (>/= 3rd line) ovarian cancer Proceedings of the AACR-NCI-EORTC International Conference on Molecular...
... bleeding combined with moderate intracranial swelling without any signs of incarceration of the brain stem Evaluation of the vascular status confirmed the initial finding of retrograde filling ... contributors in writing the manuscript KIR performed radiographs and was a major contributor in writing the manuscript CK and FH have been involved in revising the manuscript critically for important intellectual ... Allal A: Imaging of the larynx and hypopharynx Eur J Radiol 2008, 66:460-479 Juutilainen M, Vintturi J, Robinson S, Back L, Lehtonen H, Makitie AA: Laryngeal fractures: clinical findings and considerations...
... results indicated that the combination of ADV with LAM is superior to ADV alone in patients with LAM-resistant HBV infection[18,20,28] However, the overall benefits of the combination of ADV with ... and LAM incombination to cross-inhibit the corresponding drugrelated HBV mutants, thereby preventing accumulation of mutated strains with adequate fitness for replication However, the combination ... that the combination of ADV with LAM would be a good option for LAM-resistant patients Conclusion The combination of ADV with LAM was superior in inhibiting HBV replication and preventing drug...
... end point to compare treatment with the combination of infliximab and MTX with infliximab alone in AS with predominantly axial symptoms Indeed, if such a combination increases exposure to infliximab, ... recommended in clinical practice In the present study, we compared the individual exposure to infliximab of AS patients with predominantly axial symptoms receiving infliximab alone or infliximab ... drawn regarding the potential role of MTX in reducing immunogenicity in AS Our results differ from those of Maini et al [17], who found that MTX increased infliximab concentrations in RA In RA, disease...
... buthionine sulfoximine (BSO), alone or incombination Effects Effects on HIV-1 replication and cell viability of class I-selective HDACIs, MS-275 and buthionine sulfoximine (BSO), alone or incombination ... HDACIs with increased selectivity and decreased toxicity Finally, we are currently searching for novel γ-glutamyl-cysteine synthetase inhibitors acting in the nanomolar range and displaying lower ... Valproic acid, a relatively weak HDACI, was tested in a small clinical trial incombinationwith antiretroviral therapy intensified with the fusion inhibitor enfuvirtide [35,36], but some more recent...