improving outcomes with prophylactic anticoagulation in patients with cancer lessons from the american society of clinical oncology guidelines
báo cáo khoa học: "Updates in Gastrointestinal Oncology – insights from the annual meeting of the American Society of Clinical Oncology" potx
... tolerable, with the exception of higher neuropathy in the OFF arm The median OS in the OFF arm was 28 weeks, and that of the FF arm was 13 weeks, thereby fulfilling the study hypothesis There was ... presented at the 2008 ASCO annual meeting examined the strategy of using calcium and magnesium, and one study also examined intermittent administration of oxaliplatin in minimizing neurotoxicity from ... consistent with the results from the Multicenter International Study of FOLFOX in the Adjuvant Treatment of Colon Cancer (MOSAIC) reported in 2007 ASCO annual meeting [26] In MOSAIC study, the OS in...
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báo cáo khoa học: "Recent advances in gastrointestinal oncology updates and insights from the 2009 annual meeting of the American Society of Clinical Oncology" doc
... trial of gemcitabine and oxaliplatin alone or in combination with biweekly cetuximab in the first-line treatment of advanced biliary cancer: Interim analysis of the BINGO trial J Clin Oncol (Meeting ... Hsueh CT: Updates in Gastrointestinal Oncology - insights from the 2008 44th annual meeting of the American Society of Clinical Oncology J Hematol Oncol 2009, 2:9 57 Wolmark N, Yothers G, O’Connell ... in the prophylactic skin treatment arm experienced a dose delay compared with 6% of patients in the reactive skin treatment arm The data is supportive of the routine use of prophylactic skin...
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báo cáo khoa học: "Updates in non-small cell lung cancer - insights from the 2009 45th annual meeting of the American Society of Clinical Oncology" potx
... Hsueh, Updates in non-small cell lung cancer - insights from the 2009 45th annual meeting of the American Society of Clinical Oncology Journal of Hematology & Oncology 2010, 3:18 Page 11 of 11 ... decisions in the firstline treatment setting cannot be recommended at this time Lastly, there is hope for improving outcomes in the Page of 11 second-line setting given the positive data from the ZODIAC ... The important finding in this trial has demonstrated the improvement of PFS and RR from vandetanib translated into the clinically meaningful delay in symptom progression Competing interests The...
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From Cancer Patient to Cancer Survivor - Lost in Transition: An American Society of Clinical Oncology and Institute of Medicine Symposium pot
... held in conjunction with the release of the IOM report, From Cancer Patient to Cancer Survivor: Lost in Transition, represents an effort on the part of the American Society of Clinical Oncology ... president of the National Academy of Engineering The Institute of Medicine was established in 1970 by the National Academy of Sciences to secure the services of eminent members of appropriate professions ... FROM CANCER PATIENT TO CANCER SURVIVOR that is again all of what we learn in our training in terms of how we follow patients on clinical trials, the emphasis being on detecting a recurrence There...
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báo cáo khoa học: "First-in-class, first-in-human phase I results of targeted agents: Highlights of the 2008 American Society of Clinical Oncology meeting" pot
... dose in most phase I trials Finally, although evaluation of clinical efficacy is not the purpose of phase I trials, the clinical outcomes for patients enrolled in these trials is of major interest ... revolutionizing the treatment of cancer – the use of biomarkers to select individual therapies for individual patients Even from these preliminary phase I trials, where toxicity and dose-finding are the ... effects included injection site reactions, fever, and painless swelling of the lymph nodes draining the vaccination sites Immune responses to the drug were observed in 50% of patients, with a trend...
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Báo cáo y học: "Persistence with anti-tumour necrosis factor therapies in patients with psoriatic arthritis: observational study from the British Society of Rheumatology Biologics Register" pps
... to these patients In keeping with this, 73% of patients with PsA included in the present study received infliximab before the date the drug was licensed for this specific indication All of these ... defined as 'the length of time from initiation to discontinuation of therapy' [18] Patients were censored at the date therapy was stopped, the date the patient was switched to another anti-TNF therapy, ... Details of AEs leading to withdrawal of treatment for the three anti-TNF agents are presented in Table The leading cause of drug discontinuation for infliximab was infusion reactions (7.4% of patients...
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Báo cáo y học: " Is interleukin-1 a good target for therapeutic intervention in intervertebral disc degeneration: lessons from the osteoarthritic experience" pdf
... intra-articular injection of anakinra (50 or 150 mg) in 170 patients with symptomatic OA of the knee [9] There was no improvement in knee pain, function, or measures of cartilage turnover with anakinra ... L, et al.: Results from a double blind, placebo-controlled, multicenter trial of a single intra-articular injection of Anakinra (Kineret®) in patients with osteoarthritis of the knee Arthritis ... placebo at the main endpoint (month 1) A tendency for improvement was noticed in the 150 mg group at day (in keeping with the short half-life of IL-1ra), suggesting that IL-1 inhibition may be therapeutically...
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báo cáo hóa học: " Evaluation of the reliability and validity of the Medical Outcomes Study sleep scale in patients with painful diabetic peripheral neuropathy during an international clinical trial" pot
... was administered to patients in order to assess the impact of the pregabalin treatment on patients' quality of sleep We used the data from the international clinical trial to provide information ... 'worsened' patients were defined In the absence of published thresholds, the following groups of patients were defined based on the distribution of the changes in both the weekly sleep interference ... consists of a single-item with an 11-point numerical rating scale, ranging from (pain does not interfere with sleep) to 10 (pain completely interferes with sleep) that allows the calculation of a...
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Báo cáo khoa học: "Suppressive effect of culture supernatant of erythrocytes and serum from dogs infected with Babesia gibsoni on the morphological maturation of canine reticulocytes in vitro" pdf
... setycoluciter eninac fo noitarutam eht dedrater yltnacifingis setycorhtyre fo tnatanrepus erutluc dna mures detcefni inosbig B oviv ni inosbig B ortiv nI inosbig B inosbig B ,inosbig B ortiv ni inosbig ... setycoluciter eninac fo noitarutam eht no snoitcarf rieht dna htiw detcefni sgod morf mures fo tceffe ehT t p p inosbig B inosbig B inosbig B inosbig B inosbig B ortiv ni giF setycoluciter eninac fo ... morf mures fo sisylana EGAP-SDS inosbig B inosbig B inosbig giF B inosbig B esehT tnacifingis deredisnoc erew 50.0 < fo seulaV tset - s’tnedutS eht gnisu demrofrep saw sisylana lacitsitatS t...
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Báo cáo khoa học: "Protection of chicken against very virulent IBDV provided by in ovo priming with DNA vaccine and boosting with killed vaccine and the adjuvant effects of plasmid-encoded chicken interleukin-2 and interferon-g" doc
... although the priming effect of the in ovo DNA vaccine was confirmed in the DNA vaccine plus boost group Our results were consistent with those of another study using in ovo vaccination with a recombinant ... including the IBV S1 gene, was expressed in the bursa and heart of chicken embryos following the delivery of DNA vaccine into the allantoic sac, with the expression of the IBV and NDV viral proteins ... of INF-γ [7] Therefore, ChINF-γ expressed by pcDNA-ChINF-γ co-delivered with the DNA vaccine may inhibit the expression of viral genes under the control of the CMV promoter It appeared that the...
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CURRENCY BOARD OR CENTRAL BANK? Lessons from the Irish Pound''''s Link with Sterling, 1928-79 ppt
... to the banking system (including lender of last resort facilities); (iii) Maintain the liquid assets of the Government; (iv) Maintain the liquid reserves of the banking system; (v) Regulate the ... operating on March 13, 1979 without the full participation of the UK Before the end of the month, a strengthening sterling brought the Irish pound to the upper intervention limit of the EMS, and the ... Ireland, but not the UK, fully participated from the start, Irish currency remained at par with sterling From the legal point of view, the period from independence to the establishment of the European...
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GREEN PAPER - Audit Policy: Lessons from the Crisis (Text with EEA Relevance) ppt
... of a societal role in offering an opinion on the truth and fairness of the financial statements of audited entities The independence of auditors should thus be the bedrock of the audit environment ... through binding principles on top of the IFAC Code of Ethics20 Notwithstanding the legal provisions as well as the Code of Ethics referred to above, the Commission would like to reinforce the independence ... distortion within the system The Commission is considering the feasibility of a scenario where the audit role is one of statutory inspection wherein the appointment, remuneration and duration of the...
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Báo cáo khoa học: Degradation of chitosans with chitinase B from Serratia marcescens Production of chito-oligosaccharides and insight into enzyme processivity docx
... even-numbered regardless of the initial binding mode, leading to the observed initial dominance of even-numbered oligomers Interestingly, the initial formation of even-numbered oligomers all the way to at ... substrate The aglyconside of the substrate-binding groove is extended by the aromatic surface of a putative chitin-binding domain The crystal structure of ChiB further suggests that the active ... dimer mainly consists of AA (86% at a ẳ 0.11) By the end of the reaction, the relative amount of DA starts to increase, nally reaching 34% of the total amount of dimers NMR analyses of the tetramer...
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Burgoyne''''s Invasion of 1777 With an outline sketch of the American Invasion of Canada, 1775-76. pot
... Burgoyne's companions in arms have told us of the herds of red deer seen quietly browsing on the hillsides; of the flocks of pigeons, darkening the air in their flight; and of the store of pike, bass, ... against themselves as to be without order or government Of the remaining six, the resources of Orange, Ulster, and Dutchess were already heavily taxed with the duty of defending the passes of the ... that, instead of attacking, Burgoyne found himself assaulted; instead of turning Gates's left, his own was being assailed, with the purpose of separating the two wings of his army On finding a...
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Báo cáo sinh học: " Thottapalayam virus is genetically distant to the rodent-borne hantaviruses, consistent with its isolation from the Asian house shrew (Suncus murinus)" potx
... relative to the other hantaviruses In terms of coding region, the N protein central region is highly conserved This region has been shown to contain the RNA binding domain, which in the case of HTN ... to a minimal region spanning amino acids 194–204 [10] Studies of several hantaviruses have implicated the amino- and carboxy-termini in N protein interactions, and although the N protein amino-terminus ... produced in single step RT-PCR reactions using the Superscript III single step RT-PCR system with Platinum Taq High fidelity (Invitrogen) according to the manufacturer's instructions The newly...
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Báo cáo hóa học: " Thottapalayam virus is genetically distant to the rodent-borne hantaviruses, consistent with its isolation from the Asian house shrew (Suncus murinus)" pdf
... relative to the other hantaviruses In terms of coding region, the N protein central region is highly conserved This region has been shown to contain the RNA binding domain, which in the case of HTN ... to a minimal region spanning amino acids 194–204 [10] Studies of several hantaviruses have implicated the amino- and carboxy-termini in N protein interactions, and although the N protein amino-terminus ... produced in single step RT-PCR reactions using the Superscript III single step RT-PCR system with Platinum Taq High fidelity (Invitrogen) according to the manufacturer's instructions The newly...
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Báo cáo sinh học: "Inference for threshold models with variance components from the generalized linear mixed model perspective" ppt
... not included, neither in the generation of the data nor in the model fitted The negative value for this configuration indicates that, although the bias seems fairly independent of the size of the ... depend on the (relative) number of fixed effects in the model Table V shows that this is indeed so Starting from the original HG scheme, using new seeds for generating the data, the number of fixed ... direction of the bias is in line with results for GLM where bias correction often involves , S shrinkage towards the origin Possibly, the results of Cordeiro and McCullagh (1991), involving an extra...
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Báo cáo y học: " Clinical utility of tibial motor and sensory nerve conduction studies with motor recording from the flexor hallucis brevis: a methodological and reliability study" pptx
... determining all distances including the foot, as we felt it would more accurately assess the length of the tibial nerve in the medial ankle area In a cadaver comparison of surface measures of the ... for the medial plantar motor branch of the tibial nerve (S2-S3) involve recording over the motor point of the abductor hallucis muscle [13] Proper electrode placement over the motor point of the ... velocity values from the onset of the sensory waveform instead of the peak of the waveform Not all normative studies maintained temperature control, making a direct comparison with our results...
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Báo cáo y học: " Suicide amongst psychiatric in-patients who abscond from the ward: a national clinical survey" doc
... national sample of deaths in England and Wales receiving a verdict of suicide or open verdict from the Office for National Statistics (ONS) Second, information on whether the deceased within the sample ... absconding from the ward Over the 10-year study period, whilst the number of in- patient suicides had declined, the proportion who had absconded remained essentially unchanged (an average of 40% of in- patient ... provided a profile of absconders in general, including being younger [3,4], with high rates of schizophrenia [17-19], substance misuse [20], and medication noncompliance [19] The finding that patients...
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Báo cáo y học: " Integrating findings of traditional medicine with modern pharmaceutical research: the potential role of linked open data" ppsx
... gramineus Sol Based on these considerations, we explored current semantic resources and linked data technologies in order to identify their potential for improving the integration of findings from ... browsing the aggregated datasets with the aTag Explorer (Figure 2) [20] The aTag Explorer is a web interface for faceted searching and browsing of aTags on the web The RDF was loaded into the ... Chinese medicine For researchers without a strong background in Chinese medicine, the categorization of diseases, symptoms and indications according to Chinese medicine theory can be misleading and...
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- open files with administrative privileges from the file manager
- thinking animals and thinking machines what relations with particular reference to the psychoanalytical point of view
- bacteria with probiotic capabilities isolated from the digestive tract of the ornamental fish pt
- establish sterilization dose for tissues with a population different from the standard distribution of resistance sdr
- b provide a table with anticipated costs identifying the anticipated source of each detailing revenues or other operating capital you can devote to these if there is a shortfall explain how you will raise or access the appropriate funds if no add
- stew apos d veal with white sauce from the same
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- benign conditions associated with a risk for the subsequent development of cancer
- select issues in the forensic assessment of traumatic brain injury with key references from the research literature
- transposase transposable dna complex shows similarities with and differences from the hiv 1 in viral dna interaction
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- listen to the conversation then fill the blank in each of advertisement with one phrase from the box p 65
- e g ciliated cells in primary nasal mucosal tissue from healthy subjects and np patients and in vitro with hnespcs derived from the same donors
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