immunological nitric oxide synthase inos
Báo cáo khoa học: Relationship between the structure of guanidines and N-hydroxyguanidines, their binding to inducible nitric oxide synthase (iNOS) and their iNOS-catalysed oxidation to NO pptx
... substrates for nitric oxide synthases Bioorg Med Chem 10, 3049–3055 Jia Q, Cai T, Huang M, Li H, Xian M, Poulos TL & Wang PG (2003) Isoform-selective substrates of nitric oxide synthase J Med ... inducible nitric- oxide synthase J Biol Chem 276, 421–427 Gorren AC, Schmidt K & Mayer B (2002) Binding of l-arginine and imidazole suggests heterogeneity of rat brain neuronal nitric oxide synthase ... functional rat neuronal nitric oxide synthase in Escherichia coli Proc Natl Acad Sci USA 92, 8428–8432 Chen PF, Tsai AL, Berka V & Wu KK (1996) Endothelial nitric- oxide synthase Evidence for bidomain...
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Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain pdf
... mammalian nitric oxide synthase Biochem Soc Trans 31, 502–505 Nishida CR & de Montellano PR (2001) Control of electron transfer in nitric- oxide synthases Swapping of autoinhibitory elements among nitric- oxide ... WK, Cooper CE & Knowles RG (2001) Nitric oxide synthases: structure, function and inhibition Biochem J 357, 593–615 Stuehr DJ (1999) Mammalian nitric oxide synthases Biochim Biophys Acta 1411, ... B (2007) Nitric- oxide synthase: a cytochrome P450 family foster child Biochim Biophys Acta Gen Subj 1770, 432–445 Li H & Poulos TL (2005) Structure–function studies on nitric oxide synthases...
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Tài liệu Báo cáo khoa học: Polarized distribution of inducible nitric oxide synthase regulates activity in intestinal epithelial cells pdf
... on nitric- oxide synthase induction signals J Biol Chem 275, 11341–11347 FEBS Journal 272 (2005) 444–453 ª 2004 FEBS Apical iNOS dimer in epithelial cells Miller MJS & Sandoval M (1999) Nitric Oxide ... inducible nitric oxide synthase is an apical EBP50-binding protein that directs vectorial nitric oxide output J Biol Chem 277, 33132–33138 14 Baek KJ, Thiel BA, Lucas S & Stuehr DJ (1993) Macrophage Nitric ... induces nitric oxide synthase in human neutrophils J Clin Invest 99, 110–116 Daniliuc S, Bitterman H, Rahat MA, Kinarty A, Rosenzweig D & Nitza L (2003) Hypoxia inactivates inducible nitric oxide synthase...
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Báo cáo khoa học: Space, time and nitric oxide – neuronal nitric oxide synthase generates signal pulses pptx
... and the chemical reactivity of nitric oxide J Exp Med 169, 1011–1020 Abu-Soud HM & Stuehr DJ (1993) Electron transfer in the nitric- oxide synthases Nitric oxide synthases reveal FEBS Journal 276 ... (1997) A tutorial on the diffusibility and reactivity of free nitric oxide Nitric Oxide 1, 18–30 Salerno JC (2008) Neuronal nitric oxide synthase: prototype for pulsed enzymology FEBS Lett 582, 1395–1399 ... profiles of nitric- oxide synthases I, II, and III J Biol Chem 276, 48887–48898 Nishimura JS et al (1999) The stimulatory effects of Hofmeister ions on the activities of neuronal nitricoxide synthase: ...
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Báo cáo khoa học: Interference with the citrulline-based nitric oxide synthase assay by argininosuccinate lyase activity in Arabidopsis extracts docx
... (2002) Hydrogen peroxide induces a rapid production of nitric oxide in mung bean (Phaseolus aureus) Nitric Oxide 6, 205–213 41 Neill SJ, Desikan R, Clarke A & Hancock JT (2002) Nitric oxide is a novel ... Response to Zemojtel et al Plant nitric oxide synthase: back to square one Trends Plant Sci 11, 526–527 49 Guo FQ (2006) Response to Zemojtel et al Plant nitric oxide synthase: AtNOS1 is just the ... Localization of nitric- oxide synthase in plant peroxisomes J Biol Chem 274, 36729–36733 39 Delledonne M, Zeier J, Marocco A & Lamb C (2001) Signal interactions between nitric oxide and reactive...
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Báo cáo khoa học: Binding and activation of nitric oxide synthase isozymes by calmodulin EF hand pairs potx
... (2001) Nitric oxide synthases: structure, function and inhibition Biochem J 357, 593–615 ´ Roman LJ, Martasek P & Masters BS (2002) Intrinsic and extrinsic modulation of nitric oxide synthase ... nitric- oxide synthase by a dual mechanism Activation of intra- and interdomain electron transfer J Biol Chem 269, 1179–1190 Chen PF, Tsai AL, Berka V & Wu KK (1996) Endothelial nitric- oxide synthase ... of calmodulin and electron transfer by neuronal nitric oxide synthase Biochemistry 36, 12337–12345 11 Ghosh DK & Salerno JC (2003) Nitric oxide synthases: domain structure and alignment in enzyme...
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Báo cáo khoa học: Rapamycin inhibits lipopolysaccharide induction of granulocyte-colony stimulating factor and inducible nitric oxide synthase expression in macrophages by reducing the levels of octamer-binding factor-2 doc
... expression of inducible nitric oxide synthase Biol Chem 384, 1343–1364 10 Kleinert H, Pautz A, Linker K & Schwarz PM (2004) Regulation of the expression of inducible nitric oxide synthase Eur J Pharmacol ... protein kinases and phosphoinositide 3-kinase (PI3K), downstream of the TLR4-signaling pathway [3–5] Of the LPS-induced genes, those coding for inducible nitric oxide synthase (iNOS) and granulocyte-colony ... effects of immunosuppressive drugs: cyclosporin, rapamycin and FK-506 on inducible nitric oxide synthase, nitric oxide, cyclooxygenase-2 and PGE2 production Inflamm Res 49, 20–26 Lu SC, Chang SF,...
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Báo cáo khoa học: Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90 potx
... Ser1179 phosphorylation of endothelial nitric oxide synthase J Biol Chem 277, 32552–32557 Kone BC (2000) Protein–protein interactions controlling nitric oxide synthases Acta Physiol Scand 168, 27–31 ... Involvement of the proteasome in activation of endothelial nitric oxide synthase Life Sci 73, 2225–2236 Musial A & Eissa T (2001) Inducible nitric- oxide synthase is regulated by the proteasome degradation ... neuronal nitric- oxide synthase in vitro and in vivo J Biol Chem 275, 17407–17411 Hajimohammadreza I, Raser KJ, Nath R, Nadimpalli R, Scott M & Wang KKW (1997) Neuronal nitric oxide synthase and...
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Báo cáo khoa học: Cupiennin 1a, an antimicrobial peptide from the venom of the neotropical wandering spider Cupiennius salei, also inhibits the formation of nitric oxide by neuronal nitric oxide synthase pptx
... features in common with certain amphibian peptides that inhibit the formation of NO by neuronal nitric oxide synthase (nNOS) [10] These particular amphibian peptides (e.g the caerins and splendipherin ... structure is also adopted by Ca2+-CaM when it binds to the CaM-binding domain of endothelial nitric oxide synthase (eNOS) [33] The second example is when the C-terminal lobe of Ca2+-CaM binds part ... JF, Lancaster JR & Feldman PL (1995) Nitric oxide: a new paradigm for secondary messengers J Med Chem 38, 4344–4362 Stuehr DJ & Ghosh S (2000) Nitric Oxide Handbook of Experimental Pharmacology...
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Báo cáo khoa học: In vivo degradation of nitric oxide synthase (NOS) and heat shock protein 90 (HSP90) by calpain is modulated by the formation of a NOS–HSP90 heterocomplex pot
... cleavage of inducible nitric oxide synthase (iNOS) by calpain I Biochim Biophys Acta 1568, 216– 224 23 Su Y & Block ER (2000) Role of calpain in hypoxic inhibition of nitric oxide synthase activity ... apo-neuronal nitric- oxide synthase J Biol Chem 277, 20504–20509 11 Dunbar AY, Kamada Y, Jenkins GJ, Lowe ER, Billecke SS & Osawa Y (2004) Ubiquitination and degradation of neuronal nitric- oxide synthase ... Ubiquitination of inducible nitric oxide synthase is required for its degradation Proc Natl Acad Sci USA 99, 12315–12320 15 Musial A & Eissa T (2001) Inducible nitric- oxide synthase is regulated by...
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Báo cáo khoa học: Thermodynamic and kinetic analysis of the isolated FAD domain of rat neuronal nitric oxide synthase altered in the region of the FAD shielding residue Phe1395 docx
... the FAD isoalloxazine ring nNOS, rat neuronal nitric oxide synthase; eNOS, rat endothelial nitric oxide synthase; iNOS, rat inducible nitric oxide synthase; CPR, human cytochrome P450 reductase; ... & Stuehr, D.J (1995) Nitric Oxide Synthases.Properties Catalytic Mechanism Annu Rev Physiol 57, 707–736 Stuehr, D.J (1997) Structure-Function Aspects in the Nitric Oxide Synthases Annu Rev Pharmacol ... neuronal nitric- oxide synthase distinct polypeptides – identification heme-binding proximal thiolate ligand cysteine-415 Biochemistry 34, 3686–3693 13 Abu-Soud, H & Stuehr, D (1993) Nitric oxide synthases...
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Báo cáo Y học: Amphibian peptides that inhibit neuronal nitric oxide synthase The isolation of lesueurin from the skin secretion of the Australian Stony Creek Frog Litoria lesueuri docx
... of nitric oxide by nNOS? The three nitric oxide synthases, namely neuronal, endothelial and inducible, are highly regulated enzymes responsible for the synthesis of the signal molecule nitric oxide ... formation of nitric oxide by nNOS Nitric oxide has many roles in animals and plays important roles in the nervous, muscular, cardiovascular and immune systems [68] In anurans, nitric oxide is already ... S.H (1991) Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase Nature 351, 714±718 38 Marletta, M.A (1993) Nitric oxide synthase and mechanism J Biol Chem...
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báo cáo hóa học: " Signaling pathways mediating a selective induction of nitric oxide synthase II by tumor necrosis factor alpha in nerve growth factor-responsive cells" pptx
... interleukin-1beta; iNOS, inducible nitric oxide synthase; MAPK, mitogen activated protein kinase; NF-κB, nuclear factor kappa B; NGF, nerve growth factor; NO, nitric oxide; nNOS, neuronal nitric oxide synthase; ... inducible nitric oxide synthase promoter in insulin-producing cells Diabetologia 1998, 41:1101-8 Kong GY, Peng ZC, Costanzo C, Kristensson K, Bentivoglio M: Inducible nitric oxide synthase expression ... nitric oxide and dementia of the Alzheimer's type Brain Res Brain Res Rev 2001, 35:73-96 de la Monte SM, Lu BX, Sohn YK, Etienne D, Kraft J, Ganju N, Wands JR: Aberrant expression of nitric oxide...
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Báo cáo khoa học: "Enhanced expression of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomyelitis" pdf
... neuronal nitric oxide synthase Science 1994, 265(5180), 1883-1885 21 Iadecola, C., Xu, X., Zhang, F., el-Fakahany, E E and Ross, M E Marked induction of calcium-independent nitric oxide synthase ... of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomelitis 27 28 29 30 31 32 33 34 35 36 37 38 Induction of nitric oxide synthase activity in human astrocytes ... inducible nitric oxide synthase gene are susceptible to experimental autoimmune encephalomyelitis Eur J Immunol 1998, 28(4), 1332-1338 Sarih, M., Souvannavong, V and Adam, A Nitric oxide synthase...
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Báo cáo khoa học: "Immunohistochemical study of constitutive neuronal and inducible nitric oxide synthase in the central nervous system of goat with natural listeriosis" potx
... constitutively express neuronal nitric oxide synthase mRNA Nitric Oxide 1998, 2, 203-212 Hooper, D.C., Ohnishi, S.T., Kean, R., Numagami, Y., Dietzschold, B and Koprowski, H Local nitric oxide production in ... constitutively express iNOS We postulate that nitric oxide generated endogenously via either iNOS or nNOS functions as a neuroprotectant against neurotropic injury, because iNOS is known as an endogenous ... constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomyelitis J Vet Sci., 2000, 1, 11-17 11 Moncada, S., Palmer, R.M.J and Higgs, E.A Nitric oxide: physiology, pathophysiology,...
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Báo cáo khoa học: "Expression of nitric oxide synthase isoforms in the porcine ovary during follicular development" ppsx
... monoclonal anti-endothelial nitric oxide synthase (eNOS) antibody, rabbit anti-inducible nitric oxide synthase (iNOS) antisera, and rabbit anti-neuronal nitric oxide synthase (nNOS) antisera (all ... of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomyelitis J Vet Sci 2000, 1, 11-17 Knowles RG, Moncada S Nitric oxide synthases in mammals Biochem J 1994, 298, ... Estrogen 101 regulation of nitric oxide synthesis in the porcine oocyte Mol Cell Biochem 2004, 260, 13-19 Jablonka-Shariff A, Olson LM Hormonal regulation of nitric oxide synthases and their cell-specific...
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Báo cáo khoa học: " Effects of L-NAME, a non-specific nitric oxide synthase inhibitor, on AlCl3-induced toxicity in the rat forebrain cortex" doc
... neuropathology J Inorg Biochem 2001, 87, 63-69 Chabrier PE, Demerlé-Pallardy C, Auguet M Nitric oxide synthases: targets for therapeutic strategies in neurological diseases Cell Mol Life Sci ... Ivana D Stevanović et al 18 19 20 21 22 23 24 25 26 27 28 29 reduces expression of neuronal nitric oxide synthase and of soluble guanylate cyclase and impairs glutamatergic neurotransmission in ... Fernández AP, Rodrigo J, Boscá L, Leza JC Chronic stress induces the expression of inducible nitric oxide synthase in rat brain cortex J Neurochem 2000, 74, 785-791 Pelvig DP, Pakkenberg H, Regeur...
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Báo cáo y học: "Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: synergistic effect of leptin with interleukin-1" pdf
... Involvement of (NOS) oxide synthase phosphatidylinositol 3-kinase (PI3K), mitogen-activated protein kinase kinase (MEK)-1 and p38-kinase in leptin/IL-1-induced nitric oxide synthase (NOS) Dose-dependent ... human inducible nitric- oxide synthase promoter activation J Biol Chem 2001, 276:8445-8452 40 Han IO, Kim HS, Kim HC, Joe EH, Kim WK: Synergistic expression of inducible nitric oxide synthase by phorbol ... and ATDC5 cells (Fig 1d) Janus kinase-2 inhibition blocks leptin/IL-1 induced nitric oxide production and nitric oxide synthase type II protein expression We also investigated the role played by...
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Báo cáo y học: "Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes" pps
... glyceraldehyde-3-phosphate dehydrogenase; IL-1ra, IL-1 receptor antagonist; iNOS, inducible nitric oxide synthase; NO, nitric oxide; OCP, octacalcium phosphate p38 MAPK isoform In support of this possibility, ... experiments GAPDH, glyceraldehyde-3-phosphate dehydrogenase; iNOS, inducible nitric oxide synthase; JNK, c-Jun amino-terminal kinase; NO, nitric oxide; OCP, octacalcium phosphate Figure OCP crystal induced ... SB: The expression and regulation of nitric oxide synthase in human osteoarthritis-affected chondrocytes: evidence for up regulated neuronal nitric oxide synthase J Exp Med 1995, 182:2097-102...
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