immunocytochemistry for the nr1 subunit of the nmda receptor
Báo cáo y học: "Enhancement of the Click Chemistry for the Inverse Diels Alder Technology by Functionalization of Amide-Based Monomers"
... dimethyl-1,2,4,5-tetrazine-3,6-dicarboxylate The first highly active part of the construct, allows the ligation of e.g carrier molecules on the desired side of the molecule The second dienophile on the other side with lower ... of the dansyl derivative and the N-ethyl-diisoproylamine and the dansyl sulfamidoethylamine to the tetrazine product linked with 5-dansyl sulfamidoethylcarboxamide-2-yl For the syntheses of the ... 1665.9) for chemical reaction by the solid phase peptide synthesis (Figure 4) Ligation of the pentamer I with the tetrazine-dicarboxylate 6: One µmol of the pentamer I (Figure 3) and 5.5 µmol of the...
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Tài liệu Báo cáo khoa học: Cell surface nucleolin on developing muscle is a potential ligand for the axonal receptor protein tyrosine phosphatase-r ppt
... near the limit of detection for this interaction, as successive dilution of the probe soon led to loss of signal The low yields of the AP probe and of nucleolin, together with the inevitable ... (PTPr)-binding and lactoferrin-binding proteins (A) Schematic diagram of PTPr-derived proteins Shown are the two main isoforms of PTPr, PTPr1 and PTPr2 The first six subdomains of the PTPr ectodomain ... One way to understand these events might be to identify the extracellular ligands of the RPTPs in the neuromuscular system For example, it is known that PTPd and an isoform of LAR can interact...
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Tài liệu Báo cáo khoa học: Gas6 and protein S Vitamin K-dependent ligands for the Axl receptor tyrosine kinase subfamily pptx
... organs other than the liver, the main site of production of protein S and other coagulation factors [41] Before identification of its receptor, human protein S was shown to be a potent mitogen for ... and interact with the membrane, thus enabling the SHBG domain to bind to the receptor on either the same or another cell Axl, Sky and Mer in cancer The transforming activity of Axl under experimental ... FEBS 5237 The Gas6–Axl system S Hafizi and B Dahlback ¨ limit the accessibility of the cell-bound receptor to the ligand They therefore represent an important posttranslational mechanism for controlling...
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Báo cáo khoa học: Knock-out of the chloroplast-encoded PSI-J subunit of photosystem I in Nicotiana tabacum PSI-J is required for efficient electron transfer and stable accumulation of photosystem I pot
... perturbation of the luminal side of PSI involving PSI-F and PSI-N The absence of PSI-J might affect the conformation of PSI-F, which, in turn, changes the binding of PSI-N PSI-F provides part of the Pc-binding ... amounts similar to the other PSI core subunits Instead it seems plausible that the changed conformation of PSI-F in the absence of PSI-J renders a fraction of the PSI complexes inactive The in vivo ... Knock-out of the J subunit of PSI PSI-J is important for proper electron transfer On the basis of work with mutants of Chlamydomonas lacking PSI-J, it has been proposed that the function of PSI-J...
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Báo cáo khoa học: Regulation of the muscle-specific AMP-activated protein kinase a2b2c3 complexes by AMP and implications of the mutations in the c3-subunit for the AMP dependence of the enzyme docx
... equivalent to the R302Q substitution in c2, the dominant isoform of the c -subunit in the heart The R302Q mutation, together with several other substitutions identified in CBS domains of the c2 gene, ... domains both bind one molecule of AMP [20] In terms of the structure of AMPK, the b -subunit has been reported to act as a scaffold for binding of the a -subunit and c -subunit [22] Previously, we ... Regulation of AMPK a2b2c3 complexes by AMP K Lindgren et al all of which are required for its activity [8,9] In the mammalian genome, two isoforms of the a -subunit (a1 and a2) and the b-subunit...
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Báo cáo hóa học: " A rapid, convenient, solventless green approach for the synthesis of oximes using grindstone chemistry" docx
... furnish the pure oxime in 60-98% yield 90 Page of run might be due to the loss of active sites of the catalyst Conclusions To the best of our knowledge, Bi O has never been used in the synthesis of ... grounded in a mortar with a pestle for the required period of time On completion of the reaction as Table Reusability of Bi2O3 in the preparation of 2b using 60 mol% of the catalyst Entry Run number ... reusability of the catalyst using the recovered Bi O from the reaction It is observed that recovered catalyst could be satisfactorily used for the second run, whereas, third run of the recovered...
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Gums and stabilisers for the food industry 14 (special publications) royal society of chemistry (2008)
... responsible for the polydispersity of the gum The AG ữaction contains 88 % of the total gum with small amounts of protein 0.35 % which represents 20 % of the total protein content, while the AGP ... means, without the prior permission ìn writing ofThe Royal Society of Chemistry or the Copyright owner, or in the case of reprographic reproduction onìy in accordance with the terms of the ỉicences ... it is the hydrophobic moiety of the arabinogalactan protein (AGP) of the gum arabic which bridges the hydrophilic barrier to coat the oil droplet, with the driving force being directed by the entropic...
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Báo cáo y học: " Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis"
... on the prevalence in the population, and more reflective of the test itself, lessening the impact of any unique features of the VA population Moreover, we might expect that the PPV and NPV of the ... NC) Results The characteristics of the VARA participants measured at the start of each treatment episode were evaluated Because the characteristics of VARA patients at the start of non-biologic ... contrast to other RA therapies where the drugs are typically discontinued if they are not effective Because of similarities in both the descriptive characteristics of the study populations of biologic...
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Báo cáo khoa học: "Medical treatment for the terminally ill: the ‘risk of unacceptable badness’"
... end -of- life issues to patients and their families [11] It is not uncommon for physicians to ask loaded questions in their quest for end -of- life decisions For example, ‘This is your grandmother’s ... revitalize the patient population of ICU patients who will die no matter what treatment is rendered them Medically inappropriate care causes pain, suffering, and discomfort The fundamental maxim for these ... 10 11 12 13 14 Perhaps the most effective way of dealing with strong familial incentives to tread the path of least resistance in end -of- life care is twofold First, in end -of- life issue discussions,...
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Báo cáo y học: "Clinical Strategy for the Management of Solid Pseudopapillary Tumor of the Pancreas: Aggressive or Less"
... attempted for three SPT patients in whom the mass was located in the portion of body or tail of the pancreas For tumors of SPT located in the neck and body of the pancreas, resection of the midportion ... midportion of the pancreas and the mass with preserving the rim of the head and tail portion can be achieved However, for the patient in whom the mass was located within the head of the pancreas, ... 311 Fig The CT scan indicated the typical internal or capsular calcification in the SPT Once the diagnosis of SPT is made, surgery is the first choice of treatment, since other adjuvant therapies,...
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Báo cáo y học: "Endoscopic Facet Debridement for the treatment of facet arthritic pain – a novel new technique
... 100% relief of their pain in 86% of the patients with a median relief period of months The range of relief varied from zero days to up to 13 months for the facet injection group None of the lumbar ... median period of pain relief being months The range of relief for the radiofrequency group was from zero days to 16 months for all 26 patients who underwent the radiofrequency procedure Of the 14 patients ... that the direct visualization of the joint allows better de-innervation of the joint and removal of the entire end-plate receptors that adhere to the bone and capsular tissue Limitations of the...
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Báo cáo y học: "Endoscopic thoracic laminoforaminoplasty for the treatment of thoracic radiculopathy: report of 12 case"
... laminoforaminoplasty, should decrease the risk of major adverse events, allow for same day hospital discharge, and decrease the need for postoperative analgesia and immobility [5] [6] In the current ... and neural structures increases the risk of adverse events with invasive approaches Open surgical correction is the current standard of care for foraminal stenosis of cervical and lumbar vertebrae ... follow-up Results The author acknowledges that there are no conflicts of interest or financial benefits with the results of the study All twelve patients (10 males, females) completed the surgery without...
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Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"
... system, in the distal segment of the tubule Inhibition of glucose reabsorption in the kidney, mediated by the SGLT cotransport system, represents a promising therapeutic target for the control of hyperglycemia ... larvae of beetles (Chrysomelidae) Their synthesis has been previously described [31-33] For the purpose of the present study the thioglycosides used were selected and grouped based on their differences ... IC50 values of 30 µM for hSGLT1 and 10 µM for hSGLT2, while thioglycoside VII showed IC50 values of 15 µM for hSGLT1 and 88 µM for hSGLT2 These data confirm the strong inhibitory effects of thioglycoside...
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Báo cáo y học: "Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary"
... represent a single pathological entity and therefore there is no single strategy for their prevention Conflict of interest The author has declared that no conflict of interest exists References Czeizel ... birth In Hungary 25.2% of congenital abnormalities were prevented by these methods Previously the selective abortion, i.e termination of pregnancy after the prenatal diagnosis of severe fetal defects ... prevention Recently the WHO and other international bodies have excluded this approach from the term “prevention” In Hungary about 20% of major congenital abnormalities (8.7% in the total group)...
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Báo cáo y học: "Comparison of a Two-Lead, Computerized, Resting ECG Signal Analysis Device, the MultiFunction-CardioGramsm or MCG (a.k.a. 3DMP), to Quantitative Coronary Angiography for the Detection of Relevant Coronary Artery Stenosis (70%)
... large inventory of normalized mathematical indexes of abnormality It is the pattern of these mathematical indexes of abnormality, obtained from analysis of multiple cardiac cycles of the resting ... Moreover, to assess the performance of the prediction of stenosis independent of the prevalence of stenosis, the positive and negative likelihood ratios (LR) were calculated [24] A value of p
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Designing & evaluating an English reading test for the non-majors of Civil Engineering at Haiphong private university
... the scope of the study, the aims of the study, the methods of the study and finally the design of the study *Part II includes three chapters: + Chapter one is the literature review in which the ... in the previous chapter 3.1 The content area of the test The following topic checklist of the course book will help to point out the content area of the reading test The Topic checklist of the ... The mean is the sum of all the values in a distribution divided by the total number of values (50) The formula for the mean is: M = ∑f N x M= mean where: ∑= sum of (or add up) N= the number of...
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Designing an esp syllabus for the second-year students of library study at the national teachers training college
... the administrators) 3.3.3.4.2 The organization of the syllabus Basing on the results of the surveys and the official requirements of the college, we have offered an ESP reading syllabus for the ... contains of three types of cards for each item in the librarys collection The first type has the authors name or other persons or institutions The second has the title of the book or other item on the ... students based on the previous chapters The last part of the study is a summary of the study including the conclusion of the study, limitations of the study as well as suggestions for further study...
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A study on the techniques for the improvement to the teaching of oral skills in light of communicative english language teaching for junior high school teachers in quang ngai province part 1
... the aim of the lesson clear? Are the stages of the lesson clears? Does the teacher a variety of activities? Does the teacher encourage real use of language? Does the T use a warmer to begin the ... ORIGINAL STUCTURE: How often you | go | to the zoo? Introduce pictures of the park, the sports center, the mountain, the river, the kitchen and the school Check if the students know the vocabulary Set ... share exactly the same information If the task is correctly set, the students must pool their information and are thus forced to communicate through English The information gap is therefore an important...
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A study on the techniques for the improvement to the teaching of oral skills in light of communicative english language teaching for junior high school teachers in quang ngai province part 2
... UNIVERSITY, HANOI COLLEGE OF FOREIGN LANGUAGES POST GRADUATE STUDIES DEPARTMENT TRẦN QUỐC VIỆT A STUDY ON THE TECHNIQUES FOR THE IMPROVEMENT TO THE TEACHING OF ORAL SKILLS IN LIGHT OF COMMUNICATIVE ENGLISH ... COMMUNICATIVE ENGLISH LANGUAGE TEACHING FOR JUNIOR HIGH SCHOOL TEACHERS IN QUẢNG NGÃI PROVINCE (NGHIÊN CỨU CÁC THỦ THUẬT NÂNG CAO VIỆC DẠY KỸ NĂNG NGHE NÓI TIẾNG ANH THEO ĐƯỜNG HƯỚNG GIAO TIẾP CHO GIÁO ... NÓI TIẾNG ANH THEO ĐƯỜNG HƯỚNG GIAO TIẾP CHO GIÁO VIÊN TRUNG HỌC CƠ SỞ TẠI TỈNH QUẢNG NGÃI) M.A.THESIS HA NOI-2007 ...
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A study on the techniques for the improvement to the teaching of oral skills in light of communicative english language teaching for junior high school teachers in quang ngai province part 3
... College of Foreign Languages, Vietnam National University-Hanoi for their valuable lectures And their knowledge, their thoughtfulness as well as their sympathy I will always appreciate For the accomplishment ... Tiến and the staff members of Postgraduate Department, College of Foreign Languages, VNU-Hanoi for their enthusiastic support I am sincerely grateful to Mr Đinh Tấn Bảo and my colleagues of Foreign ... Teachers Training College for their attention and encouragement I am appreciative of all those who have kindly advised and helped me during the period of my study at College of Foreign Languages, VNU-Hanoi...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008