human immunodeficiency virus type 1 infection chronic inflammation and programmed cell death in the central nervous system
Báo cáo y học: " Genotyping of TRIM5 locus in northern pig-tailed macaques (Macaca leonina), a primate species susceptible to Human Immunodeficiency Virus type 1 infection" pps
... 2303, 2 415 , 2494, 2506 and 2529) are in the coding region (39%), and the others (site 16 9, 248, 252, 350, 364, 462, 12 62, 12 65, 14 40, 17 18, 17 19, 17 21, 17 23, 17 59, 17 65, 19 12, 2034, 2037, 2057, ... http://www.retrovirology.com/content/6 /1/ 58 A 62 524 -1 KMZ-2 -1 50 528 -1 83 87 015 -1 97203 -1 65 932 01- 1 992 01- 1 5 51- 1 64 KMZ-5 -1 KMZ -1- 1 KMZ-4 -1 B C KMZ-4 KMZ -1 992 01 524 KMZ-5 97203 56 932 01 M.nem 5 51 87 015 M.mul KMZ-2 ... Yunnan, China Yunnan, China Yunnan, China Yunnan, China Yunnan, China Yunnan, China Yunnan, China Yunnan, China 19 98-4 -15 19 88-4-5 2000 -11 2008-4 -11 2008-4 -11 2008-4 -11 2008-4 -11 2008-3-28 2008-3-28...
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Báo cáo hóa học: " The inhibition of the Human Immunodeficiency Virus type 1 activity by crude and purified human pregnancy plug mucus and mucins in an inhibition assay" ppt
... that the mucin inhibits HIV -1 infection by physically aggregating the virus than by blocking putative viral binding sites or receptors on the cells The virus and mucins were incubated together ... leaving no free viruses to pass through the filter paper into the filtrate to cause viral infection On the other hand the 10 0% infection of the CEM-SS cells caused by the filtrates from the mixtures ... pregnancy plug inhibited HIV -1 infection of the CEM SS cells However, the crude pregnancy plug mucus and the media failed to inhibit HIV -1 infection of these cells Though the mechanism of inhibition...
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Báo cáo khoa học: The silencing of adenine nucleotide translocase isoform 1 induces oxidative stress and programmed cell death in ADF human glioblastoma cells doc
... transfection (Fig 6E) 10 1 FL2-H 10 2 10 3 10 1 LQ: 3% 10 0 10 1 FL2-H 10 2 10 3 UQ: 97% LQ: 97% 10 0 10 2 10 3 FL1-H 10 4 10 1 D 10 0 Fig Analysis of ANT1-silencing on DW dissipation and the effect of the mitochondrial ... ANT1-silencing According to this hypothesis, we found that ANT1 siRNA-treated cells 10 2 FL1-H 10 3 10 4 10 3 10 4 UQ: 86% 10 3 10 4 LQ: 14 % 10 0 10 1 10 2 FL1-H F E than in ANT2 siRNA- and Scramble-transfected cells, ... Scramble-transfected cells (F) ANT1 siRNAa-transfected cells 10 1 10 1 10 0 LQ: 2.5% 10 0 C UQ: 3% FL2-H 10 2 10 3 FL2-H 10 2 10 3 UQ: 97.5% 10 4 A 10 4 ANT1-silencing induces glioblastoma cell death 10 4 A Lena et al show...
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mutations on human immunodeficiency virus type 1
... species of viruses; between the inactivated viruses and live viruses III Viral interference Mechanisms of viral interference: a .Virus A may inhibit virus B adsorption by blocking or destroying receptors ... Uncoating: The process that capsid is removed and viral nucleic acid is released in the host cell Biosynthesis: Eclipse phase Biosynthesis includes: Viral genome replication Viral protein synthesis ... Enveloped viruses: usually released by budding During budding enveloped viruses acquire their envelope – Defective measles virus: release from cell to cell via cell bridges ↓ SSPE (Subacute sclerosing...
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Báo cáo hóa học: " Toll-like receptor 9 polymorphisms influence mother-to-child transmission of human immunodeficiency virus type 1" pptx
... Diagnosis of HIV -1 infection was performed by virus isolation and polymerase chain reaction (PCR) [10 ] For all children included in this study, 11 8 HIV -1- infected and 18 2 HIV1-uninfected, the infection ... variety of inflammatory and infectious diseases [6-8 ,17 ,18 ] Table 1: Frequencies of TLR9 genotypes and haplotypes and risk of HIV -1 infection SNP Genotypes Uninfected children (n = 18 2) Infected ... polymorphisms and perinatal HIV -1 infection has not been investigated The present study focuses on the role of c.4-44G > A and c .16 35A > G SNPs in the TLR9 gene in MTCT of HIV -1 by analyzing a large...
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Báo cáo sinh học: " Oligomerization of the human immunodeficiency virus type 1 (HIV-1) Vpu protein – a genetic, biochemical and biophysical analysis" ppt
... of the cytoplasmic domain J Virol 19 96, 70:2669-2673 Page 10 of 11 (page number not for citation purposes) Virology Journal 2007, 4: 81 10 11 12 13 14 15 16 17 18 19 20 21 22 Cohen EA, Terwilliger ... recruits other proteins such as Skp1, Cul -1 and the Cdc34 E2 ubiquitin ligase [11 ] This results in ubiquitination of CD4, its dislocation from the ER and degradation by the proteosome [12 ,13 ] The stable ... [8] The Vpu protein binds CD4 in the endoplasmic reticulum (ER) [9], and through its phosphoserine residues binds the beta transducin-repeat containing protein (βTrCP) in the cytoplasm [10 ] The...
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Báo cáo sinh học: " Inhibition of human immunodeficiency virus type-1 (HIV-1) glycoprotein-mediated cell-cell fusion by immunor (IM28)" docx
... of TF228 .1. 16 cells with SupT1 cells Effect of2 Effect of dexamethasone on fusion of TF228 .1. 16 cells with SupT1 cells TF228 .1. 16 cells were mixed with SupT 11 cells (1: 1 cell ratio) and transferred ... IM28 on fusion of TF228 .1. 16 cells with SupT1 cells TF228 .1. 16 cells were mixed with SupT 11 cells (1: 1 cell ratio) and transferred to a 24-well plate (10 5 cells per well in 200 µl of cultured medium) ... Virology Journal 2005, 2:9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 and for LESTR/fusin and blocks HIV -1 entry Nature 19 96, 382:829-33 Cocchi F, DeVico AL, Garzino-Demo A, Arya SK, Gallo...
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Báo cáo hóa học: " Human Immunodeficiency Virus type 1 in seronegative infants born to HIV-1-infected mothers" doc
... http://www.virologyj.com/content/3 /1/ 52 infected persons and infants born to HIV -1- infected mothers [3-6] In case of the pediatric infections some of these children appear to have eliminated virus- infected cells [3], others ... against HIV infection: has nature done the experiment for us Immunol Today 19 96, 17 : 21- 24 Beretta A, Weiss SH, Rappocciolo G, Clerici M: Human immunodeficiency virus type (HIV -1) seronegative infection ... long terminal repeat sequences from long-term survivors of human immunodeficiency virus type infection J Virol 19 97, 71: 5608-5 613 Frenkel LM, Mullins JI, Learn GH, Manns-Arcuino L, Herring BL,...
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báo cáo hóa học:" Inhibition of human immunodeficiency virus type-1 (HIV-1) glycoprotein-mediated cell-cell fusion by immunor (IM28)" docx
... of TF228 .1. 16 cells with SupT1 cells Effect of2 Effect of dexamethasone on fusion of TF228 .1. 16 cells with SupT1 cells TF228 .1. 16 cells were mixed with SupT 11 cells (1: 1 cell ratio) and transferred ... IM28 on fusion of TF228 .1. 16 cells with SupT1 cells TF228 .1. 16 cells were mixed with SupT 11 cells (1: 1 cell ratio) and transferred to a 24-well plate (10 5 cells per well in 200 µl of cultured medium) ... Virology Journal 2005, 2:9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 and for LESTR/fusin and blocks HIV -1 entry Nature 19 96, 382:829-33 Cocchi F, DeVico AL, Garzino-Demo A, Arya SK, Gallo...
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Báo cáo y học: " Monitoring processed, mature Human Immunodeficiency Virus type 1 particles immediately following treatme" pps
... immunodeficiency virus type (HIV -1) Leukemia 19 94, 8(Suppl 1) :S175-S178 Page of (page number not for citation purposes) AIDS Research and Therapy 2005, 2:2 10 11 12 13 14 15 16 17 18 19 20 Arts EJ, Wainberg ... the increase in precursor gag protein following treatment with LPV and NVP Comparing the drop in viral RNA load to the increase in precursor gag protein following treatment with LPV and NVP The ... containing the matrix (MA) p17 and CA p24, i.e 41 kDa In these experiments, the HXB2 p55:p24 is increasing over the first 72 hours of 20 nM LPV treatment indicating an inhibition of gag processing...
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Báo cáo y học: "Inhibition of human immunodeficiency virus type-1 by cdk inhibitors" pdf
... HIV -1 infected cells Methods Cell lines and reagents The latently HIV -1- infected promyelocytic OM10 .1 cell line, the latently infected promonocytic U1 cell line and the uninfected corresponding ... Screening of twenty-four inhibitors in HIV -1 infected and uninfected cells We analyzed the effects of twenty four different cdk inhibitors in HIV -1 infected cells ACH2, OM10 .1, J1 -1, U1 and uninfected ... cdk2 and other cyclins in drug treated cells, we found lower levels of cdk2 and cyclins in infected cells and not in uninfected cells Downregulation of cdk2, cyclin A, cyclin T, and cyclin E in infected...
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Báo cáo y học: "Autoprocessing of human immunodeficiency virus type 1 protease miniprecursor fusions in mammalian cells" pptx
... equine infectious anemia virus Gag p9 in viral budding and infection J Virol 20 01, 75(20):9762-9770 doi :10 .11 86 /17 42-6405-7-27 Cite this article as: Huang and Chen: Autoprocessing of human immunodeficiency ... autoprocessing in the context of the provirus, which is missing in the GST fusion precursor system In the context of the provirus, a combination of reduced catalytic activity and a viable suppressing ... inhibition of assembly and budding of virus- like particles Virology 19 93, 19 3(2):6 61- 6 71 16 Krausslich HG: Human immunodeficiency virus proteinase dimer as component of the viral polyprotein prevents particle...
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Báo cáo y học: " Human immunodeficiency virus type 1 Vpr: oligomerization is an essential feature for its incorporation into virus particles" ppsx
... Vpr of human immunodeficiency virus type triggers activation of apoptotic events and enhances fas-induced apoptosis in human T cells J Virol 2009, 83 :11 283 -11 297 doi: 10 .11 86 /17 43-422X-7 -11 9 Cite ... Direct Vpr-Vpr interaction in Venkatachari et al Virology Journal 2 010 , 7 :11 9 http://www.virologyj.com/content/7 /1/ 119 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 cells monitored ... acids in the N terminal region including the helical domains are essential for stability and virion incorporation and a region comprising the Helix III and the C terminal region determines the...
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Báo cáo y học: "Near full-length genome analysis of low prevalent human immunodeficiency virus type 1 subclade F1 in São Paulo, Brazil" docx
... F1.RO .19 96.BCI15 F1.RO .19 96.BCI16 86 F1.RO .19 96.BCI19 79 F1.ES.-.P 114 6 F1.AO.20 01. HDC240 F1.AO.20 01. 01AOSNS48 F1.CD .19 97.KP35 76 F1.CD .19 97.KP40 F1.RO .19 96.BCI17 F1.AO.20 01. 01AOCSE 116 F1.AO.20 01. 01AOHAB85 ... F1.RO .19 96.BCI13 F1.RO .19 96.BCI 11 77 84 F1.FR .19 95.BCB85 75 F1.AO.20 01. 01AOCSE126 F1.RO .19 96.BCI20 90 75 F1.RO .19 96.BCI18 F1.FR .19 96.MP 411 72 F1.CD.2003.CgCHU31ENV 81 F1.CD.2002.02DC KTB0 41 F1.CD .19 99.99CD70 718 6 ... F1.CD .19 99.99CD70 718 6 85 F1.CD .19 97.KTB50 F1.SN .19 97.97SE 8FANN 74 81 F1.CD.2003.CgCHU08env 79 F1.RO .19 94.BCI2 F1.CD .19 85.85CD2 41 F1.ES.-.X1670 F1.RO .19 96.BCI12 F1.RO .19 94.BCI1 82 F1.RO .19 96.BCI15...
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Báo cáo y học: "Phenotypic and genotypic characterization of Human Immunodeficiency Virus type 1 CRF07_BC strains circulating in the Xinjiang Province of China" pot
... XJDC1353 XJDC63 71 XJDC0793 XJDC0 015 CBJB105 XJDC64 31 XJN 013 5 CBJB257 CBJB256 XJDC19 81 XJDC63 31 XJDC62 91 SHXDC168 SHXDC162 SHXDC148 2 010 0 311 202 011 88 2 010 1324 2 010 1 810 2 010 0374 2 010 1796 2 010 014 1 ... XJDC19 81 SHXDC148 SHXDC168 SHXDC162 2 010 0 311 202 011 88 2 010 1324 2 010 1 810 2 010 0374 2 010 1796 2 010 014 1 2 010 0 419 20200407 20200084 2 010 0687 20200068 20200092 20200259 20200079 2020 010 8 2 010 0096 Tro- V3 sequence* ... (2005CB52 310 3 and 2005CB522903), the National Nature Science Foundation (30872232) and the NIAID, NIH of the United States (U19 A1S1 915 -03) 14 15 16 17 18 19 20 21 References 10 11 12 13 Kuiken...
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Báo cáo y học: "A single amino acid substitution of the human immunodeficiency virus type 1 capsid protein affects viral sensitivity to TRIM5α" potx
... http://www.retrovirology.com/content/7 /1/ 58 Page of 10 10 000 10 00 p24 ng/mL 10 0 10 0 .1 CEMss (Hu) 0. 01 15 10 Days after infection 20 25 10 000 10 00 p24 ng/mL 10 0 10 0 .1 MT4 (Hu) 0. 01 15 10 Days after infection 20 25 ... p24 ng/mL 10 00 10 000 NL-4/5SG 116 E6/7S vifS 10 0 .1 0. 01 10 0 .1 0. 01 100 0. 01 Days after infection Days after infection CM TRIM5α Hu TRIM5α Days after infection CM SPRY(–) TRIM5α B 10 000 10 000 NL4-3 ... 4/5 G1 S 6/7 6E 11 4/5 SG 0 .1 100 10 0 ** 60 40 60 40 Hu TRIM5α CM SPRY(–) TRIM5α E 10 16 Viral dose p24 (ng) G1 0 .1 20 G1 20 WT 10 80 % infection 80 WT 10 G 116 E Hu TRIM5α CM TRIM5α 10 0 % infection...
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Báo cáo y học: "Mutations in matrix and SP1 repair the packaging specificity of a Human Immunodeficiency Virus Type 1 mutant by reducing the association of Gag with spliced viral RN" ppsx
... NLΔSL1 to generate NLΔSL1- 913 , NLΔSL1 -19 07 and NLΔSL1- 913 / 19 07 strains The mutant vectors were identical to the NLΔSL1 sequence, except that NLΔSL1- 913 contained a G 913 A substitution in the MA ... characterization targeting cellular Y1, Y3 and SRP RNA The amount of cellular RNA in the NL4-3 virion was set at 10 0% Copy numbers for Y1, Y3 and SRP RNA were 275-362, 1, 710 2,006 and 1. 1 × 10 6 -1. 3 × 10 6, respectively, ... 2000, 3 01: 4 91- 511 Page 11 of 12 17 Berkowitz R, Fisher J, Goff SP: RNA packaging Curr Top Microbiol Immunol 19 96, 214 :17 7- 218 18 Freed EO: HIV -1 gag proteins: diverse functions in the virus life...
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Báo cáo y học: "A Functional Role for ADAM10 in Human Immunodeficiency Virus Type-1 Replication" pptx
... with 10 % FBS, 0.2 mg/mL G 418 , 0 .1 mg/mL hygromycin, and 1. 0 μg/ mL puromycin [75] Rat intestinal epithelial (RIE -1) cells were maintained in DMEM supplemented with 10 % FBS, penicillin, and streptomycin ... substrates are involved in cellular adhesion, including ephrin-A2 (EFNA2), AXL, fractalkine (CX3CL1), CXCL16, E- and N-cadherin (CHD1 and 2), the g-protocadherins C3 and B4, NCAM, CHL1, LAG-3, CD23, ... by detaching cells in PBS/2 mM EDTA and staining cells using either a mouse anti -human ADAM10 antibody (R&D Systems, Minneapolis, MN) or an IgG1 isotype control (Southern Biotech, Birmingham,...
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