how a drug or class iii medical device is approved for use premarket
Báo cáo khoa học: Human salivary a-amylase Trp58 situated at subsite )2 is critical for enzyme activity potx
... Diffraction data were collected on a Mar Research imaging plate area detector system (W58L) or on a Rigaku R-AXIS IV + image plate area ˚ detector (W5 8A) using Cu Ka radiation (1.5418 A) generated ... acarbose-soaked human pancreatic a- amylase mutant D300N [12] It is known that a- amylases, can display transglycosylation activity in the crystal in which the cleavage products are rearranged to form an extended ... UMDNJ for the mass spectral data Part of this work is based upon the use of the X-ray diffraction facilities in the University of California at San Diego and California Institute of Technology This...
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báo cáo khoa học: " A var2 leaf variegation suppressor locus, SUPPRESSOR OF VARIEGATION3, encodes a putative chloroplast translation elongation factor that is important for chloroplast development in the cold" docx
... this article as: Liu et al.: A var2 leaf variegation suppressor locus, SUPPRESSOR OF VARIEGATION3, encodes a putative chloroplast translation elongation factor that is important for chloroplast ... USA) Manipulation of nucleic acids The CTAB method was used to extract Arabidopsis leaf DNA [81], and the Trizol RNA reagent (Invitrogen, CA, USA) was used to extract total leaf RNA RNA gel analysis ... factor This is consistent with our data that SVR3 is not essential for plant growth and chloroplast biogenesis at normal growth temperature The subtle phenotype of svr3 at normal temperature and...
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Báo cáo y học: "Evaluation of the psychometric properties of a modified version of the Social Phobia Screening Questionnaire for use in adolescents" pdf
... used for the assessment of social anxiety disorder in children The Social Phobia Inventory (SPIN) [29-31] has a more categorical format and has primarily been used with adolescents The SPIN and ... widely used and well established instruments are the Social Anxiety Scale for Children - Revised (SASC-R) [24], the Social Anxiety Scale for Adolescents (SAS -A) [25] and the Social Phobia and Anxiety ... Statistical analyses Chi-square or Fisher's exact tests were used for evaluating group differences with respect to categorical variables Test-retest reliability was assessed using Spearman's correlation...
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17% of cell phone owners do most of their online browsing on their phone, rather than a computer or other device pdf
... relative sizes of each frame and each sample The second stage of weighting balances sample demographics to population parameters The sample is balanced to match national population parameters for ... non-Hispanic subgroup is also balanced on age, education and region The basic weighting parameters came from a special analysis of the Census Bureau’s 2011 Annual Social and Economic Supplement (ASEC) ... received at least one daytime call in an attempt to find someone available For the landline sample, interviewers asked to speak with the youngest adult male or female currently at home based on a random...
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báo cáo khoa học:" Sinus lifting before Le Fort I maxillary osteotomy: a suitable method for oral rehabilitation of edentulous patients with skelettal class-III conditions: review of the literature and report of a case" doc
... of vertical alveolar grafting for augmentation without implant Orthoalveolar form is the concept for optimal restauration of the edentulous alveolar ridge and means an idealized alveolar bone ... bone mass and ortholalveolar form [6] This can be achieved by augmentation of the available substrate using established techniques such as vertical and lateral augmentation of the alveolar ridge, ... posterior maxilla and a skelettal class III jaw relationship amongst others due to the cleft palate Minor degree maxillary alveolar atrophy was found in the anterior maxilla because of the still remaining...
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Báo cáo khoa học: " Proteomics computational analyses suggest that the bornavirus glycoprotein is a class III viral fusion protein (γ penetrene)" pot
... Rhabdoviridae G class III F Paramyxoviridae HA TPMV-like class henipa class I I Paramyxovirinae pre class I, II, III Pneumovirinae F HA class class I I Paramyxoviridae avula metapneumo Mononegavirales ... by an ancestral paramyxoviruses and class III VFP of a common ancestor of rhabdoviruses and bornaviruses A variation of this former tree (not shown) would involve separate acquisitions of class ... Carbone KM, Duchala CS, Griffin JW, Kincaid AL, Narayan O: Pathogenesis of Borna disease in rats: evidence that intraaxonal spread is the major route for virus dissemination and the determinant...
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Stability and in vivo evaluation of pullulan acetate as a drug nanocarrier
... 1.0 (Anhui, China) program Bioavailability (BA) is a measurement of the rate and extent of a therapeutically active drug that reaches the systemic circulation and is available at the site of action ... monitored for changes in food intake and body weight at 1, 8, and 15 days After being sacrificed at 15 days, internal organs of each animal were harvested and observed grossly For histological examinations, ... When a medication is administered intravenously, its bioavailability is 100% When the standard consists of intravenously administered drug, this is known as relative bioavailability (BAR) The BAR...
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Tài liệu Primer For Class Iii & Class Iv Milk Futures And Options Traders(pdf) pptx
... expiration and be automatically offset at the USDA’s announced price for Class III and IV Milk What is a Futures Contract? A futures contract is a legally binding obligation to buy or sell a commodity ... orders to use and help provide both fundamental and technical information on market price outlook To locate a broker, you might ask around, or give us a call How to Trade Milk Class III or Class ... a positive way for you, your account is credited accordingly The following example is based on $1,000 performance bond requirements and a maintenance margin of $800 for each Milk contract (Margins...
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Tài liệu Lab 5.2.7 Establishing a Console Connection to a Router or Switch docx
... connectors a Examine the router or switch and locate the RJ-45 connector labeled “Console” Step Identify the computer serial interface, which is COM or a It should be a or 25-pin male connector labeled ... connector If the serial interface on the PC or dumb terminal is a DB-25, an RJ-45 to DB-25 adapter will be needed Both of these adapters typically come with a Cisco router or switch Step Locate or ... Locate or build a rollover cable Use a rollover cable If necessary, make one of adequate length to connect the router or switch to a workstation 2-6 CCNA 1: Networking Basics v 3.0 - Lab 5.2.7 Copyright...
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Tài liệu Customer Relationship Management: A Database Approach - Class 6 pptx
... retention rate, so Rrt=survival rate for t periods • • LTV is a measure of a single customer’s worth to the firm Used for pedagogical and conceptual purposes LTV: Definition Accounting for Acquisition ... present value in May dollars By comparing this score among a set of customers a prioritization is arrived at for directing future marketing efforts Lifetime Value metrics (Net Present Value models) ... Churn: Lost for Good or Missing in Action States of Customer: S0 = bought this period S-1 = last bought one period before State Transition (Markov Matrix) Before S0 S-1 S0 0.7 S-1 0.3 Lost for Good...
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Tài liệu Báo cáo Y học: Structural diversity and transcription of class III peroxidases from Arabidopsis thaliana docx
... AtPCb AtPEa AtP3 AtP2 AtP9 AtP8 AtP11 AtP4 AtP19 AtP17 AtP15 AtPRC AtP12 AtP13 AtP6 AtP35 AtP10 AtP21 AtP5 AtP34 AtP23 AtP24 AtP27 AtP22 AtP41 AtP38 AtPN AtP7 AtPA2 AtP29 AtP20 AtP26 AtPCa AtP32 AtP31 ... 57 AtP2 73 peroxidases from Arabidopsis (Eur J Biochem 269) 6073 AtPCa AtP16 AtPEa AtPA2 AtPN AtP6 AtP31 AtP18 AtP5 AtP23 AtP4 AtP17 AtP32 AtP3 AtP15 AtP24 AtP13 AtP14 AtP7 AtP19 AtP11 AtP12 AtP33 ... from Table Peroxidase Clone origin Whole plant (day) Root Rosette Stem Cauline leaf Flower bud AtP1 AtP2 AtP7 AtP9 AtP16 AtP17 AtP32 AtP15 AtP24 AtP4 AtPCb AtP8 AtP26 AtPCa AtPEa AtP13 AtP31 AtP23...
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Đề tài " A stable trace formula III. Proof of the main theorems" pptx
... and (2), that yield a stable trace formula A STABLE TRACE FORMULA III 771 Parts (a) of the theorems apply to “endoscopic” analogues of the terms in the trace formula They assert that the endoscopic ... goal is A STABLE TRACE FORMULA III 801 to show that each side of the identity in question vanishes, by the comparison of a distribution that is discrete in ν with one that is continuous This is ... spectral side, by means of an application of the 772 JAMES ARTHUR trace formula for M The cancellation of singularities comes in showing that for suitable v ∈ V and fv ∈ H G(Fv ) , a certain difference...
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Báo cáo khoa học: How a lipid mediates tumour suppression Delivered on 29 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden pdf
... can also not be excluded that PI3K -III may act as tumour suppressor by additional means For example, SARA, a mediator of transforming growth factor-b signalling, requires PtdIns3P binding for ... domain-containing protein 1) that are considered to act as platforms for autophagosome formation This suggests a role for WIPI2 in the progression from omegasomes into autophagosomes PI3K -III and ... fact that Vps34 was originally identified as a mediator of protein sorting, studies of both yeast and mammalian cells have shown that PI3K -III is required for proper sorting of certain membrane...
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Báo cáo khoa học: Phaiodotoxin, a novel structural class of insect-toxin isolated from the venom of the Mexican scorpion Anuroctonus phaiodactylus pdf
... phaiodactylus, collected in Baja California, Mexico We have isolated and chemically and functionally characterized this peptide The gene that codes for the toxin and several isoforms were obtained ... were obtained from data bank and the abbreviations stand for: AaH, Androctonus australis Hector; Amm, Androctonus mauretanicus mauretanicus; Bj, Buthotus judaicus; Bot, Buthus occitanus tunetanus; ... were used for Edman degradation analysis The molecular mass determination of pure phaiodotoxin and the additional sequencing work was performed by mass spectrometry, using an LCQDuo Finnigan mass...
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Overview of the Aesthetic Medical Device Market docx
... Comparable Companies Analysis - Aesthetic Medical Devices Market Comparable Companies Analysis • Most pure-play aesthetic medical device companies are relatively small, with market capitalizations ... company is based in Germany and was a subsidiary of WaveLight AG Acquisition 6.2 Quantel Medical SA 6/4/2007 Lumenis Ltd Lumenis designs, manufactures and markets medical devices which employ laser, ... Aesthetic Medical Devices Market (cont’d.) Key Financial Data • Founded in 1969 and headquartered Wayland, Massachusetts (Wayland, Massachusetts) Description ($ in millions) 200 4A 200 5A 2006A...
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THE PRESIDENT’S PLAN FOR A STRONG MIDDLE CLASS & A STRONG AMERICA pptx
... development on federal lands and offshore, has broad non-partisan support, including retired admirals and generals and leading CEOs It is focused around one achievable goal: shifting our cars and trucks ... information about college: Last year, President Obama called for the development of a new College Scorecard to give students and families clear information about college costs and quality as ... recover their wages He then created an inter-agency Equal Pay Task Force to crack down on equal pay law violations The President is committed to closing the pay gap once and for all and is calling on...
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Báo cáo khoa học: Structural and biological effects of a b2- or b3-amino acid insertion in a peptide Application to molecular recognition of substance P by the neurokinin-1 receptor ppt
... three b-amino acid-substituted SP analogues [HGly9]SP, [b2-HAla9]SP and [b3-HAla9]SP may adopt conformations around residue that are analogous to those adopted by a- amino acids (Gly, Ala, Sar, Pro) ... only a part of the representative statistical ensemble, due to the h angle restriction HGly has a wide range of accessible conformations, whereas b3-HAla has a more limited conformational space ... variations demonstrate the formation of more stable and abundant helical structures for [Aib9]SP than for SP By restrained molecular dynamics, [Aib9]SP has been shown to adopt a stable helix from...
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Báo cáo Y học: A catalytically inactive b1,4-N-acetylglucosaminyltransferase III (GnT-III) behaves as a dominant negative GnT-III inhibitor potx
... overlapping peaks of asialo-agalacto biantennary and asialo-agalacto tetraantennary sugar chains; right, asialo, agalacto triantennary sugar chain containing a b1,4-GlcNAc residue on the Mana1,3 arm ... wild-type GnT-IIItransfectant (b) and D32 3A- transfectant (c) Numbers at the top indicate peaks for bisected sugar chains: 1, asialo-agalacto-bisected biantennary sugar chain; 2, asialo-agalactobisected ... tetraantennary sugar chain; 3, asialoagalacto-bisected triantennary sugar chain containing a b1,4-GlcNAc residue on the Mana1,3 arm Arrowheads indicate nonbisected sugar chains: left arrowhead,...
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Medical Device ISO 13485:2003 Voluntary Audit Report Submission Pilot Program ppt
... Secretary shall accept voluntary submissions of reports of audits assessing conformance with appropriate quality system standards set by the International Organization for Standardization (ISO) and ... the audit/inspection according to basic Health Canada and FDA requirements Informal and anecdotal comments received by FDA and Health Canada personnel from the participating manufacturers and auditors ... organization can perform a single audit/inspection of a medical device manufacturer's quality management system (QMS) in order to satisfy the regulatory requirements of Health Canada and FDA In addition,...
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