host related factors and biological features of acute myeloid leukemia aml in the elderly
Summary of Phd thesis Pecies composition of gobiidae and eleotridae and biological aspects of some commercial species distributed in the coastal areas of Ben Tre province
... stabilising at 0‰ during a period of months (8/2012 – 12/2012) The variation of salinity caused by the heavy precipitation in the rainy season and the intrusion of marine water to freshwater in the ... higher in the dry that in the rainy season In the annual salt effect regions, salinity increased gradually from 12/2012 to 3/2013 reaching the highest point of 28±1‰, but there was a downtrend of ... determine the fish composition and biological characteristics of gobies (Gobiidae and Eleotridae) using for fishery management and sustainable development in the Mekong Delta in generally and Ben...
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A study of semantic and syntactic features of idioms relating to fruits in english and vietnamese
... of the Study The study aims at: - Investigating the semantic and syntactic features of English and Vietnamese idioms relating to fruits (IsRTFs) in the combined analysis of both features - Finding ... them in their daily life These are the results: In short, in this chapter, we have described and analyzed the Firstly, in term of semantics, in the total of groups of semantic and syntactic features ... idioms In fact, metaphor is the concept of understanding one thing in 4.3 SIMILARITIES AND DIFFERENCES IN SEMANTIC terms of another Interestingly, metaphor is used in the two languages AND SYNTACTIC...
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Báo cáo sinh học: "Curcumin reduces expression of Bcl-2, leading to apoptosis in daunorubicin-insensitive CD34+ acute myeloid leukemia cell lines and primary sorted CD34+ acute myeloid leukemia cells" pptx
... an indicator of poor prognosis in AML [3] In the present study, we evaluated the cytotoxicity of curcumin in DNR-insensitive CD34+ AML cell lines (KG1a and Kasumi-1) and in CD34+ primary AML ... participated in its design and coordination DX contributed effort in designing, performing, and analyzing the results and conclusion All authors read and approved the final manuscript Competing interests ... S, Khanin M, Studzinski GP, Danilenko M: Distinct combinatorial effects of the plant polyphenols curcumin, carnosic acid, and silibinin on proliferation and apoptosis in acute myeloid leukemia...
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Báo cáo y học: "Downstream molecular pathways of FLT3 in the pathogenesis of acute myeloid leukemia: biology and therapeutic implications" pps
... [69-82] The compounds currently in development are heterocyclic compounds containing components that structurally mimic the purine ring of adenosine and become inserted into the ATP-binding site of ... pathogenesis of AML, and numerous genetic abnormalities in AML have been identified FLT3 is one of the key molecules with a role in the pathogenesis in AML During the past decade, the function of the ... effects of ATO and MEK inhibition, as well as ATO and FLT3 inhibition, on FLT3-ITD cells [101] The combination of ATO and AG1296, an FLT3 inhibitor, profoundly inhibited the growth and induced...
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báo cáo khoa học: "Isolation of specific and biologically active peptides that bind cells from patients with acute myeloid leukemia (AML)" doc
... two different AML patients Incubation with 100-fold concentration of nonbiotinylated HP-A2 resulted in blocking the binding of the biotinylated HP-A2 Similarly, HP-G7 and HP-B6 binding was specifically ... identical for AML and CML-BC cells, implying that the binding of the peptides was myeloid leukemia specific rather than CML-BC specific Since AML specimens were more readily available, all further studies ... using AML cells Peptide binding profiles Ten biotin-conjugated peptides were synthesized and tested for their ability to bind leukemia and normal BM cells in a cytochemistry assay (Table 2) The...
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báo cáo khoa học: "Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report" docx
... documented The finger joints were slightly deformed, and the membranes of these joints showed mild synovial and lymphoid proliferation These findings were compatible with the pathological findings of ... ×800) B and C: Hematoxylin and eosin (HE) staining and double immunohistochemistry analyses of BM biopsy (B) and skin biopsy (C) B: HE showed the diffuse infiltration of small lymphocytes into BM ... factor of LPD [25] It remains unclear whether the co-existence of the three conditions are coincidental or there could be an intrinsic mechanism Conclusion The current case with AML- MLD and EBV-associated...
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Báo cáo y học: " Clinical presentation and endoscopic features of primary gastric Burkitt lymphoma in childhood, presenting as a protein-losing enteropathy: a case report" pptx
... occurred, and there was a rapid rise in serum albumin and protein with resolution of clinical signs of protein-losing enteropathy Further chemotherapy included two courses of cyclophosphamide, vincristine, ... competing interests Authors’ contributions JC and JG abstracted the clinical data and coordinated the initial preparation of images JC prepared the initial draft manuscript SD reviewed the endoscopic ... Computed tomography (CT) of the chest and abdomen showed multiple exophytic lesions in the stomach, several filling defects within the jejunum, and a cm long intussusception in the ileum (Figure 2)...
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Báo cáo y học: "Cost of acute renal replacement therapy in the intensive care unit: results from The Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Study" pps
... represent the absolute range between the maximum nursing cost of CRRT and the minimum nursing cost of IRRT on the right, and between the maximum nursing cost of IRRT and minimum nursing cost of CRRT ... domain The error bars represent the range between the maximum cost of each domain for CRRT and the minimum cost for IRRT and the maximum cost of each domain for IRRT and minimum cost for CRRT The ... on the left The box represents the 1st and 3rd quartiles of the nursing-cost range The thick solid line represents the median difference in nursing costs for CRRT and IRRT across all centers in...
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In vitro and in vivo study of ABT 869 in treatment acute myeloid leukemia (AML) alone or in combination with chemotherapy or HDAC inhibitors insight into molecular mechanism and biologic characterization
... In vitro and In vivo study of ABT-869 in treatment acute myeloid leukemia (AML) alone or in combination with chemotherapy or HDAC inhibitors: insight into molecular mechanism and biologic ... down-regulated cyclins D and E by 16h and induced the expression of p21waf1/Cip progressively The increasing expression of cyclin E in MV4-11 cells at 4h, in MOLM-14 cells at 1h and cyclin D in MOLM-14 ... Phosphoinositide 3-kinase Promyelocytic Leukemia Zinc Finger protein Phosphatase of Regenerating Liver Retinoblastoma Protein Red Fluorescence Protein RNA interference Receptor Tyrosine Kinase Standard...
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Tài liệu Báo cáo Y học: Antibacterial and antifungal properties of a-helical, cationic peptides in the venom of scorpions from southern Africa pptx
... enabling the disruption of the outer membrane and facilitating the interaction of the toxin with the inner membrane In the presence of high Mg2+ ions, the MIC of compounds that are taken up via the ... opistoporins (34%) and pandinin (31%) This means that there is a high conservation in amino acid sequence of the peptides in the venom of scorpions that belong to the same family, independent of the ... belonging to the same family, independent of the continent and region where they live In this study, the biological activity of parabutoporin and opistoporin is compared with the activity of melittin...
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Báo cáo khoa học: Structural and functional consequences of single amino acid substitutions in the pyrimidine base binding pocket of Escherichia coli CMP kinase pdf
... with the amino group and the N3 atom of the cytosine (Fig 1) This study uses site-directed mutagenesis to further explore the contribution of these amino acids interacting with the pyrimidine ring ... consisting of three domains, the CORE, the LID and the NMPbind [1] A characteristic of bacterial CMP kinases is an extension of the NMPbind domain by 40 amino acid residues forming a three-stranded ... proportion of dimers were formed, even in the case of the wild-type protein as indicated by ESI-MS or SDS PAGE in the absence of reducing agents The proportion of dimers increased notably in D132A and...
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Analysis of socio-economic factors affecting technical efficiency of small-holder coffee farming in the Krong Ana Watershed, Dak Lak Province, Vietnam
... estimate the technical efficiency of coffee production and evaluate factors affecting the level of technical inefficiency of small holder coffee farmers in the Krong Ana Watershed of Dak Lak province ... largest coffee producers in the world, there is minimal research and information regarding coffee production in this area, in particular, efficient coffee production and socio-economic factors influence ... Coffee is the major agricultural crop and plays a crucial role in the well-being of people in the province In 2009, total coffee planted area in the province was 181,960 hectares accounting for...
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báo cáo hóa học: " A comparative study on approximate entropy measure and poincaré plot indexes of minimum foot clearance variability in the elderly during walking" pptx
... values The value of ApEn reflecting the degree of irregularity, randomness and complexity of the MFC time series data, could therefore, indicate the degree of stability in the control of foot ... representation of a time series into a Cartesian plane, where the values of each pair of successive elements of the time series define a point in the plot Indexes derived from Poincaré plot of minimum ... of surrogate data was aimed at destroying the underlying control mechanism and to increase the degree of randomness Absence of correlation of mean MFC with ApEn and increased values of ApEn in...
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Báo cáo lâm nghiệp: " Humus conditions and stand characteristics of artificially established young stands in the process of the transformation of spruce monocultures" pdf
... of a forest ecosystem from the point of view of the element cycle preservation in forest ecosystems and maintaining their ecological stability The condition and form of humus in forest ... (in nKCl) pH was determined In the surface humus, values of both actual and exchangeable pH decrease with increasing depth (Figs and 3) in all stands and the lowest values were determined in the ... findings of Berger et al (2002), we can note that in mixed stands of spruce (larch) with beech, the content of total carbon and nitrogen is lower than in the spruce stand The main indicator of...
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Báo cáo lâm nghiệp: "reproductive and morphometric characteristics of wild boar (Sus scrofa) in the Czech republic" pot
... joint to the tip of the hoof, ear length (LA) from the root of the ear to the tip, and height at the withers (AC) as the distance from the tip of the fore leg to the highest point at the withers ... both the time of farrowing and the morphometric parameters This confirms the findings of Maillard and Fournier (2004) that in case there is an abundance of food available during the preceding ... than the value given by Moretti (1995) in Switzerland At the age of 9–10 and 11–12 months, the body length is greater in the Kostelec area, and it is the same in the Doupov area and Šumava as in...
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Báo cáo y học: "Monoclonal Antibodies against Nucleophosmin Mutants: Potentials for the Detection of Acute Myeloid Leukemia" ppt
... epitope of NPM-mA protein and confirmed it may exist in the C-terminal domain of the NPM-mA by using the Protean module of DNAstar analysis software However, our results revealed that the obtained ... with the BamH I and Hind III 3.3 Expression and purification of recombinant NPM-mA antigen The NPM-mA fusion protein was resoluble and detected in the culture supernatants SDS-PAGE analysis of the ... Discussion Mutations involving the NPM1 gene are the most frequent genetic aberrations of AML, and define a clinically distinct subset of AML [21, 22] NPM1 gene mutations always result in cytoplasmic...
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Báo cáo sinh học: "Cytogenetic and molecular characterization of eight new reciprocal translocations in the pig species. Estimation of their incidence in French populations" pot
... far [4,10] In France, the very important development of artificial insemination (AI) since the end of the 1980’s [12] has resulted in an intensification of the control programmes, and in a drastic ... chromosome painting: metaphase spread of a pig heterozygous carrier of the rearrangement 393 394 A Ducos et al (breakpoint near the centromere, in the 5p12 band) by the main part of the long arms of one ... revealed the presence of a very thin p-terminal green band on the der(5) chromosome, demonstrating the reciprocity of the exchange, and allowed an accurate localization of the breakpoint on the p-terminal...
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Role of misfolded nuclear receptor co repressor (n cor) induced transcriptional de regulation in the pathogenesis of acute monocytic leukemia (AML m5
... types of cancers, it is most widely implicated in the pathogenesis of AML, especially in AMLs involving the AML1 -ETO fusion protein and in Acute Promyelocytic Leukemia (APL/ AML- M3) 12 In AML1 -ETO ... invaluable input on some of the work done in this thesis and for taking the time to vet my thesis; A/Prof Chng Wee Joo and Prof Norio Asou for their kind assistance with the patient samples and ... underlying the MCDL of N-CoR and its implication in the malignant growth and transformation of AML- M5 leukemic cells We also explored the potential of the MCDL of N-CoR as a therapeutic target in AMLM5...
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Báo cáo y học: "bEstrogen, not intrinsic aging, is the major regulator of delayed human wound healing in the elderly" docx
... removing any effects of 'intrinsic aging') [9] Thus, using comparative analysis we are now in a position to address the relative contributions of estrogen and aging to healing in elderly humans Since ... and prostate, it has not previously been shown to be estrogen regulated in skin Again, this novel finding may be important in light of the role of arginase in modulating the balance between inflammation ... occurs in the elderly [2] Insulin degradation in diabetic wounds has been associated with delayed healing [19] and insulin-degrading enzyme (IDE) is downregulated 20-fold in the aged and represented...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25