homeostatic mechanisms are evolutionarily conserved for transient inflammatory reactions—their misuse in chronic disabling inflammatory diseases
Is there information in financial analysts forecasts about firms that subsequently restate their earnings
... and Jenkins, 2004) We are interested to examine the role of financial analysts in producing and disseminating information about these earnings restatement firms In particular, FAF contain any ... contains comprehensive information including macroeconomic events, industry information and firm-specific non-accounting information, while time-series models rely exclusively on accounting information ... prospective financial information of certain publicly traded firms, they report earnings forecasts for the firms and make recommendations about investing in those firms’ securities Financial analysts’...
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Tài liệu Báo cáo khoa học: "The Structure of User-Adviser Dialogues: Is there Method in their Madness?" pdf
... and realizing topic continuity in a dialogue Since new topics are introduced at the beginning of new subdialogues and developed in the following sentences, one can predict that pronominal noun ... Noun Selecting the proper antecedent for a non-pronominal definite noun phrase anaphor is less difficult than for pronominal anaphor since more semantic information is provided for matching the ... determinant of which discourse entities are held in focus and are readily accessible for anaphora resolution Subdialogues that are in focus are contexts that are used to restrict the search for...
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báo cáo hóa học:" CRP identifies homeostatic immune oscillations in cancer patients: a potential treatment targeting tool?" pdf
... after initiation unless the plasma level is maintained high by continued CRP production in response to continued antigen exposure and inflammation It therefore represents a good marker for disease ... this in clinical practice at present, we are currently actively exploring some of these exciting avenues of investigation Chemotherapy We have investigated this hypothesis further by examining ... Timing of Vaccinations with the CRP cycle in a patient with advanced melanoma Timing of Vaccinations with the CRP cycle in a patient with advanced melanoma Multiple fortnightly doses of vaccine...
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báo cáo hóa học: " Quality of life data as prognostic indicators of survival in cancer patients: an overview of the literature from 1982 to 2008" pot
... appeared in 1987 This paper compared quality of life during chemotherapy for advanced breast cancer between patients receiving intermittent and continuous treatment strategies The findings indicated ... that pain and appetite loss are independent determinants of overall survival One found that a 40-point increase in the pain subscale of the EORTC QLQ-C30 was associated with a 27% increase in the ... functioning and performance status in the regression models, the likelihood of finding inconsistent results can be expected In other words, in such circumstances in some studies physical functioning...
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báo cáo hóa học:" Pain in cancer. An outcome research project to evaluate the epidemiology, the quality and the effects of pain treatment in cancer patients" pptx
... practice for cases included in the prospective cohort study are provided free as in all centers they are standard care for patients requiring analgesic treatments for pain control, according to ... endpoint is the reduction in Adequacy of analgesic-drug therapy: Patient Management index (PMI), categorized in a binary variable according to negative (indicating inadequate analgesic care) ... Pain 2000, 88:287-294 Farrar JT, Young JP Jr, LaMoreaux L, Werth JL, Poole RM: Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale Pain...
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Báo cáo khoa học: "Ultrasound-guided central venous catheterization in cancer patients improves the success rate of cannulation and reduces mechanical complications: A prospective observational study of 1,978 consecutive catheterizations" pps
... attempted in the internal jugular vein, subclavian vein, femoral vein, or arm veins using peripherally central catheters It is estimated that several million devices are inserted each year, facilitating ... procedure was early applied as a guidance for CVC insertion in the internal jugular vein in cancer patients before the recommendations from the Agency for Healthcare Research and Quality were available ... anesthesia, internal medicine, emergency medicine and family medicine housestaff used ultrasound guidance for most CVC placements [20] Since in our department oncologists and hematologists have performed...
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Báo cáo khoa học: "Perioperative immune responses in cancer patients undergoing digestive surgeries" pptx
... equal volume of 4% formaldehyde fixative After washing and incubating with PBS/BSA/saponin for 10 min, cells were incubated with for 30 min, respectively Results were analyzed using the XL/XL-MCL ... 2.7% in gastric resection, 4.5 ± 2.7% in colorectal resection, 5.5 ± 2.8% in hepatic resection and 3.2 ± 3.0% in LC) compared with before surgery (4.1 ± 2.5% in gastric resection, 2.6 ± 1.5% in ... cells producing IL-4 than that of LC and healthy control groups Interestingly, no significant differences were observed according to staging in patients with malignant disease: 6.9 ± 3.5 in stage...
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Báo cáo khoa học: " Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence" doc
... dimeric (inactive) state [16] The protein contains several important domains such as 1) the C-terminal protein kinase domain (PI3K-domain), 2) the substrate binding domain in the N-terminal of ... illustration of the protein with important areas such as substrate binding domains, Leucine zipper, ATP-binding domains, FAT domain and PI3K domain [17] together with exonic information (The size ... the minor allele with increasing level of radiation induced side effects indicating a protective effect for the A allele The C to T transition in exon 31 (rs1800058) altering the aminoacid in position...
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báo cáo khoa học: "The potential benefits of low-molecular-weight heparins in cancer patients" ppsx
... warfarin in bleeding outcomes in this study (RR 0.91; 95% CI: 0.64-1.31) On the strength of these findings the available guidelines Page of 12 increasingly recommend the LMWHs over warfarin for ... over warfarin in cancer patients in terms of practicality of use as well as in efficacy Cost comparisons The costs involved in managing VTE in general are considerable In the US managing DVT alone ... unfractionated heparin *For definitions of major bleeding see original studies † Included non-cancer patients for routine thromboprophylaxis in medical cancer patients [1,16-19] However, in the Fundamental...
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Báo cáo y học: "Is Phytalgic® a goldmine for osteoarthritis patients or is there something fishy about this nutraceutical? A summary of findings and risk-of-bias assessment" pot
... Glucosamine for pain in osteoarthritis: why trial results differ? Arthritis Rheum 2007, 56:2267-2277 10 Reginster JY: The efficacy of glucosamine sulfate in osteoarthritis: financial and nonfinancial ... diacerein (ES = –0.24) [8], we have never seen anything as efficacious as Phytalgic® [3] The same thing applies in the glucosamine area It is now becoming evident that preparations with glucosamine ... reasonable that at baseline the patients in the study groups were similar with respect to prognostic factors The reporting of double-blinding supports a low risk of performance bias as the authors...
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Báo cáo khoa học: "Performance of six severity-of-illness scores in cancer patients requiring admission to the intensive care unit: a prospective observational study" pot
... in oncology and/or R195 intensive care, and take part in regular training of oncology and intensive care nurses The nurse/patient ratio ranges from 1.2 to 1.7 Routine clinical rounds, including ... Decisions to forgo life-sustaining therapy in ICU patients independently predict hospital death Intensive Care Med 2003, 29:1895-1901 Moreno R, Matos R: Outcome prediction in intensive care Solving the ... predicting outcome, and neither should they be used for triage and cost containment in individual patients Available online http://ccforum.com/content/8/4/R194 Competing interests None declared...
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Báo cáo y học: "Clinical review: Specific aspects of acute renal failure in cancer patients" pot
... develops in 20% to 40% of BMT recipients [47] Amphotericin during conditioning Acyclovir during conditioning Vancomycin during conditioning The main site of liver damage in this setting is the ... Intern Med 1990, 150:1693-1695 Available online http://ccforum.com/content/10/2/211 20 Ying WZ, Sanders PW: Mapping the binding domain of immunoglobulin light chains for Tamm-Horsfall protein ... microangiopathies in the intensive care unit Intensive Care Med 2005, 31:71-78 33 Allford SL, Hunt BJ, Rose P, Machin SJ, Haemostasis and Thrombosis Task Force, Committee for Standards in Haematology: Guidelines...
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Báo cáo khoa học: "N-terminal pro-brain natriuretic peptide as an early prognostic factor in cancer patients developing septic shock" pdf
... December 2005 After receiving approval from our institutional ethics committee and obtaining the informed consent of the patients or next of kin, we performed the study in 51 consecutive adult ... were routinely administered in our patients presenting septic shock Hemodynamic exploration, using echocardiography or a Swan-Ganz catheter, was routinely performed in all patients presenting septic ... expansion (using crystalloids or colloids) was firstly used to increase blood pressure Then, the use of epinephrine, norepinephrine, and/or dobutamine was decided by the physician in charge of...
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Báo cáo y học: " C-reactive protein in critically ill cancer patients with sepsis: influence of neutropenia" doc
... treatmentrelated data For the purpose of the present study, individual organ failures were diagnosed in case of a SOFA score ≥ points in each domain [14] In addition, patients receiving dialysis in the context ... of infection Demographic, clinical and laboratory data were collected using standardized case report forms during the first day of ICU stay including main diagnosis for admission, the Simplified ... random sample of patients Data were screened in detail by three investigators (MS, JIFS, VCSD) for missing information, implausible and outlying values Continuous variables were reported as mean ±...
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báo cáo khoa học: "Magnitude of risks and benefits of the addition of bevacizumab to chemotherapy for advanced breast cancer patients: Meta-regression analysis of randomized trials" ppt
... that are observed in studies that explore the benefits determined by the polychemotherapy compared to single drug therapy, are well comparable with the increase in hypertension that occurs in patients ... SOLTI0701: A Multinational Double-Blind, Randomized Phase 2b Study Evaluating the Efficacy and Safety of Sorafenib Compared to Placebo When Administered in Combination with Capecitabine in Patients ... compare well with those obtained in other studies that have investigated the addition of another drug in the taxane-based chemotherapy In the study of Albain et al [28], the addition of gemcitabine...
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The NR4A orphan nuclear receptors are target genes of the novel drug c1 in cancer cells and potential mediators of drug induced apoptosis
... spectrins, microtubular proteins including tubulins, microtubule associated proteins, and intermediate filament proteins including vimentin keratin and nuclear lamins (Luthi and Martin, 2007; Taylor et ... it 116 kDa intact form into 85 kDa and 25 kDa fragments This process separates the aminoterminal DNA-binding domain of the enzyme from the carboxy-terminal catalytic domain resulting in the loss ... varying degrees of success with photodynamic therapy for the derivation of molecules of interest in cancer therapy including photofrin, purpurins, xanthenes, phthalocyanines, oxazines, cyanines,...
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The Retinoblastoma Gene Family in Cell Cycle Regulation and Suppression of Tumorigenesis
... while the pocket-domain and the C-domain are involved in binding E2F proteins Mdm2 (as well as c-Abl) binds to the C-domain All pocket proteins are subject to phosphorylation (indicated with “P”) ... of cyclin protein levels or by inducing members of the INK4A and/or CIP/KIP family of cyclin dependent kinase inhibitors (CKI), resulting in the down-regulation of cyclin/Cdk activity and inhibition ... promoters containing paired-like homeodomain protein binding sites The observation that pRb can bind simultaneous Pax-5 and the TATA-binding protein TBP, suggested a mechanism for inhibition of...
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báo cáo khoa học: "Chemoradiotherapy followed by surgery versus surgery alone in esophageal cancer patients: is it time for additional evidence?" doc
... M, Hornby J, Xu W, Ringash J, Keshavjee S, Chen E, Haider M, Darling G: Phase trial of preoperative irinotecan plus cisplatin and conformal radiotherapy, followed by surgery for esophageal cancer ... cisplatin, fluorouracil, radiotherapy, and surgery compared with surgery alone for esophageal cancer: CALGB 9781 J Clin Oncol 2008, 26(7):1086-92 Knox JJ, Wong R, Visbal AL, Horgan AM, Guindi M, ... advantage of: • Convenient online submission • Thorough peer review • No space constraints or color figure charges • Immediate publication on acceptance • Inclusion in PubMed, CAS, Scopus and Google...
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Báo cáo khoa học: "Postmastectomy irradiation in breast in breast cancer patients with T1-2 and 1-3 positive axillary lymph nodes: Is there a role for radiation therapy" ppsx
... role of PMRT for women with to positive lymph nodes remains uncertain and is being examined in a randomized clinical trial” Many surgeons and radiation oncologist are not recommending PMRT to ... crude way of defining a potential indication for PMRT More information may come from other clinicopathologic parameters (e.g., capsule and lymphovascular invasion, malignancy grading, etc.) Moreover, ... extranodal extension in our series As for DM, lymphatic invasion had an impact on LRRs existing in out of (83%) All LRRs in RT group were T2 tumors (3 cm and cm) but only of LRRs in no-RT group was...
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báo cáo hóa học:" Comparative study on the immunogenicity between an HLA-A24-restricted cytotoxic T-cell epitope derived from survivin and that from its splice variant survivin-2B in oral cancer patients" pot
... survivin-2α and survivin-3B are truncated forms, survivin2B results from alternating splicing at the interface between exon and exon 3, leading to insertion of an additional exon, termed exon 2B, in ... re-screened the total amino acid sequence of wild type survivin protein for peptides containing HLA-A24-binding motif In our previous report, two peptides, survivin85-93 and survivin92-101, derived ... http://www.translational-medicine.com/content/7/1/1 Figure Western blotting analysis of survivin protein in oral cancer cell lines Western blotting analysis of survivin protein in oral cancer cell lines Lysates...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008