gross anatomy of the human heart pdf
anatomy of the human body - henry gray
... VII. The Veins 1. Introduction2. The Pulmonary Veins3. The Systemic Veins a. The Veins of the Heart b. The Veins of the Head and Neck 1. The Veins of the Exterior of the Head and Face2. The ... Anatomy of the Human Body. 1918. 7. The Notochord The notochord (Fig. 19) consists of a rod of cells situated on the ventral aspect of the neural tube; it constitutes the foundation of the ... of the Neck3. The Diploic Veins4. The Veins of the Brain5. The Sinuses of the Dura Mater. Ophthalmic Veins and Emissary Veinsc. The Veins of the Upper Extremity and Thorax d. The Veins of...
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Báo cáo khoa học: The protein shuffle Sequential interactions among components of the human nucleotide excision repair pathway pdf
... late steps of the process. For example, early in the NER process, RPA assists TFIIH in the opening of the DNA helix around the damage site [36]. Further-more, in the presence of the XPA minimal ... sites.Taken together, these findings suggest that the struc-tural properties of DNA-damaged substrates, whetherintrinsic or the result of protein binding, function in the recruitment of the XPC–hHR23B ... Binding of XPG induces the release of XPC–hHR23B, whereas XPF–ERCC1 triggers exci-sion of the damaged DNA and the release of XPAand TFIIH. Subsequently, the newly formed gap in the DNA is filled by...
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Báo cáo Y học: Activation of transcription of the human presenilin 1 gene by 12-O-tetradecanoylphorbol 13-acetate pdf
... increases the rate of transcription initiation of the PS1 gene in SK-N-SH cellsTo determine whether the increase in the level of PS1mRNA results from the activation of the transcription of the gene ... in the presence of TPA. Thus the increase in the level of PS1 mRNA observed by Northern blotting of totalcellular RNA results from an increase in the rate of initiation of transcription of PS1.PS1 ... interactions of the )10region of the PS1 promoter with nuclear factors, including the amount of complexes involving Ets1/2 factors.DISCUSSION The loss of PKC is a prognostic element in the severity of neuronal...
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Báo cáo khoa học: Arg143 and Lys192 of the human mast cell chymase mediate the preference for acidic amino acids in position P2¢ of substrates pdf
... number of poten-tial substrates during the screening of the full human proteome. This highlights the importance of factorsother than the extended cleavage specificity in deter-mining whether ... in 6% of the sequences. Thus, Arg143 and Lys192 contributealmost equally to the P2Â specicity of HC. Mutatingeither of the two basic amino acids in these positionspartially disrupts the acidic ... orGlu, but attract these residues equally well, probablysolely on the basis on the negative charge of their sidechains.Verifying the consensus sequence by the use of anew type of recombinant...
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Báo cáo khoa học: Alanine screening of the intracellular loops of the human bradykinin B2 receptor – effects on receptor maintenance, G protein activation and internalization pdf
... Although the processes of signaling and regulation of human B2R are, in general, fairly well understood, the knowl-edge of the molecular basis of these events at the struc-tural level of the receptor ... throughchanges in the overall structure of the receptor. Thus,these data demonstrate the connection between the structure of ICLs and that of the binding site, implyingreciprocally that changes at the binding ... the respective construct name next to them. The pointmutations E66A in the first loop and T242A at the end of the third loop are also indicated. The two-dimensional structure of B2R, with the membrane...
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Báo cáo khoa học: Constitutive expression of the human peroxiredoxin V gene contributes to protection of the genome from oxidative DNA lesions and to suppression of transcription of noncoding DNA pdf
... in the regulation of these genes. It should be noted that,although the exact positions of the AREs are not con-served between different mammalian species, at least50% of all AREs in all of these ... bars)shows the results of analysis of 8-oxoG in the controland KD-1 cells. In the KD-1 cells, the concentration of endogenous 8-oxoG was significantly increased,indicating that PRDX5 contributed to the ... silencing of the human PRDX5 gene, we also constructed stable clones of the cultured airway epithelial cell line A549, which hassignificant down-regulation of this gene clone, andanalyzed the concentration...
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Báo cáo khoa học: Thioredoxin reductase from the malaria mosquito Anopheles gambiae Comparisons with the orthologous enzymes of Plasmodium falciparum and the human host pdf
... [34] between the fruit fly and the mosquito, not only the basic principles of redox metabolism and the genomicorganization of the TrxR gene, but also the mechanisticpeculiarities of these orthologous ... support the assumption that the substitution of the Trx system for GR, as well as the mechanistic particularities of the TrxR, are a commonprinciple in dipteran insects. In the context of the malarialsystem, ... reaction of the cata-lytic cycle, of course, represents the net reaction catalyzed byTrxR.Discussion The isolation and characterization of A. gambiae TrxRcontributes to the understanding of the...
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Báo cáo y học: "Expression of hMSH2 protein of the human DNA mismatch repair system in oral lichen planus"
... all of the OLP epithelium. The count was performed by two investigators without knowledge of whether the samples were control or experimental. The total number of basal and suprabasal epithelial ... Negative controls consisted of omission of the primary or the secondary antibody or primary incubation in the presence of non-immunized rabbit serum instead of the primary antibody. Cell quantification ... OLP would require an increased immunolocalization of hMSH2. Therefore, the reduced expression of hMSH2 protein could make the epithelium of OLP more susceptible to DNA mutation, making it prone...
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Tài liệu Decision Analysis and Risk Management: Two Sides of the Same Coin pdf
... based on analysis of risk. The thoroughness of the analysis determines the “quality” of the decisions.High quality decisions are not the best decisions in hindsight. They are the best decisions ... decisions in which the magni-tude of the risk of being wrong is understood. The quality of decisions can therefore be judged by the degree to which uncertainties (risks) are considered in the decision ... then related to the four steps of the decision making process and finally to the three types of error (risk) that occur in each of the four steps. The paper concludes with an example of how methodical...
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Tài liệu McGraw.Hill.Mathematics.Of.The.Securities.Industry pdf
... to the right of the decimal is less than 5 (4,3, 2, 1, or 0), then ignore all digits after the second one to the right of the decimal.Example: In the number 98.74285, the third digit after the ... digits to the right of the decimal place, for example,98.74 rather than 98.74285.To round off to two decimal places, you must examine the third digit to the right of the decimal.●If the third ... date. The company announces the amount of the div-idend, the record date, and the payment date. Soonthereafter, a fourth date, the ex-dividend date, is set byeither a stock exchange or the National...
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Tài liệu Multimedia Applications of the Wavelet Transform pdf
... [Sch01d].A historic overview of the development of the wavelet theory precedes the introduction of the (one–dimensional) continuous wavelet transform. Here, the definition of a wavelet and basic propertiesare ... analysis andsynthesis [GM85] [GMP85].In 1985, the mathematician Meyer heard of the work of Morlet and Grossmann. He was convincedthat, unlike the dyadic approach of Morlet and Grossmann, a good ... between the wavelet transform and the Fourier transform are usually restricted to the special case of the STFT. The calculation of the Heisenberg boxes of time–frequency uncertainty for the STFT...
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