getbounds retrieves the minimum x xmin minimum y ymin maximum x xmax and maximum y xmax values of the movie clip called square relative to the root coordinates and stores that information in your boundary object call
Báo cáo y học: "Prediction of prognostic biomarkers for Interferon-based therapy to Hepatitis C Virus patients: a metaanalysis of the NS5A protein in subtypes 1a, 1b, and 3a" doc
... of the body or head of the rule) and confidence (conditional probability of the body given the head of the rule) Several algorithms have been implemented in association rule mining including the ... non-responders in subtypes 1b and 3a There were statistically significant variations in the IRRDR regions (2326, 2342 and 2349 in subtype 1a; 2332, 2348 and 2383 in subtype 3a) For the whole of the NS5A ... protein, discriminative variations clustered in the IRRDR region and its flanking parts only No observable variations were present in other parts of the NS5A protein, and in the 2'5' OAS binding...
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Báo cáo khoa học: A strategy for the generation of specific human antibodies by directed evolution and phage display An example of a single-chain antibody fragment that neutralizes a major component of scorpion venom docx
... majority affecting sodium channels Despite Cn2 being the major toxic peptide, there are other toxins similar in toxicity but lower in concentration This could imply that the toxicity of the whole ... poisoning 30 post injection The first deadly effects of the toxin occurred 1.5 h after the injection It is noteworthy that mice injected with the antibody ⁄ toxin mix did not present any symptoms ... shows the reliability of the fitting The total yield was typically 700 lgÆL)1 of culture To determine the neutralization capacity and binding kinetics, only the monomeric fraction was used The BIACORE...
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Báo cáo hóa học: " The evolution of human influenza A viruses from 1999 to 2006: A complete genome study" docx
... are involved in receptor binding sites in the HA, therefore the changes observed at these sites in our dataset may influence receptor binding Amino acids defining the Tcell epitopes (after the ... The H1N1 component in the vaccine for that season matched the H1 and the H3N2 component matched the N2 subtypes of the reassortant strain Thereby, the new strain was expected fully covered by ... prevalence of sentinel and routine influenza A viruses in Denmark 1999 to 2006 Relative Relative prevalence of sentinel and routine influenza A viruses in Denmark 1999 to 2006 The actual numbers of influenza...
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Báo cáo y học: "Use of soluble MHC class II/peptide multimers to detect antigen-specific T cells in human disease." pps
... then the intensity of fluorescent staining with MHC/peptide multimers can be used as a measure of the affinity of the TCR for the MHC/peptide Binding of the multimer was shown to be mostly independent ... purified by immunoaffinity chromatography Biotinylation by the BirA enzyme is accomplished through an added peptide tag on the carboxy terminus of the β-chain, and the molecules are multimerized by adding ... cytochrome c They found that only ~1% of CD4+ T cells stained with the I-Ek/cytochrome c multimer after the first immunization, and found that this frequency only marginally increased following...
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Báo cáo y học: "Replication of recently identified systemic lupus erythematosus genetic associations: a case–control study" pps
... participated in design of the study, in genotyping the samples, in interpretation of the results and in writing the manuscript MC participated in the statistical analysis and in the interpretation of results ... pathways of Toll-like receptors/IL-1R [24] Tyk2 is a Janus-family tyrosine kinase that is bound to cytokine receptors and becomes activated after ligand binding Deficiency of TYK2 leads to defects of ... collection of samples and participated in the analysis and interpretation of results AG participated in the design of the study and in the coordination of acquisition of clinical data and collection of...
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Báo cáo y học: " Role of inflammation in túbulo-interstitial damage associated to obstructive nephropathy" pps
... ICAM1 and the presence of alpha-smooth muscle actin (a marker of myofibroblasts) [59] Other proinflammatory cytokines Macrophage migratory inhibitory factor (MIF) is a proinflammatory cytokine which ... suggest that oxidative stress is increased in the obstructed kidney, and that increased oxidative stress plays a role in inducing an inflammatory state and in deteriorating the renal function of the ... renin-angiotensin II system seems to play a major role in activating NF-κB and they contribute also to the overexpression of pro-inflammatory cytokines in the obstructive nephropathy As many therapeutic...
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Báo cáo y học: "Role of inflammation in túbulo-interstitial damage associated to obstructive nephropathy" pptx
... ICAM1 and the presence of alpha-smooth muscle actin (a marker of myofibroblasts) [59] Other proinflammatory cytokines Macrophage migratory inhibitory factor (MIF) is a proinflammatory cytokine which ... suggest that oxidative stress is increased in the obstructed kidney, and that increased oxidative stress plays a role in inducing an inflammatory state and in deteriorating the renal function of the ... renin-angiotensin II system seems to play a major role in activating NF-κB and they contribute also to the overexpression of pro-inflammatory cytokines in the obstructive nephropathy As many therapeutic...
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Báo cáo y học: "Cleavage of functional IL-2 receptor alpha chain (CD25) from murine corneal and conjunctival epithelia by MMP-9" pptx
... 1(D-E), there is a clear decrease in the intensity of the CD25 band in the DS5 in corneal and conjunctival epithelia To investigate the role of gelatinases (MMP-2, MMP-9) in the loss of CD25 in response ... Farley WJ, Li DQ, Stern ME, Pflugfelder SC: Corticosteroid and doxycycline suppress MMP9 and inflammatory cytokine expression, MAPK activation in the corneal epithelium in experimental dry eye Exp ... localization of CD25 and CD122 in the ocular surface epithelia were investigated by immunofluorescent staining (Figure 1) and the intensity of the staining was analyzed in digital images (Figure 2A) Using...
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Báo cáo y học: " Treatment of alcohol dependence with low-dose topiramate: an open-label controlled study" ppt
... alcohol, including tolerance, dependence and withdrawal [35] On the other hand, topiramate enhances the inhibitory function of GABA, antagonizes excitatory glutamate receptors, and inhibits dopamine ... finding of the present study is that low-dose topiramate given as a treatment adjunct is well-accepted and effective in reducing craving for alcohol and symptoms of anxiety and depression during ... dependence, topiramate has been found to be inferior to disulfiram in terms of days to relapse [31] and superior to naltrexone in reducing craving [32] and improving some other critical measures of drinking...
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Báo cáo y học: "Incidence of multiple Herpesvirus infection in HIV seropositive patients, a big concern for Eastern Indian scenario" ppt
... part of the preliminary investigation on the dynamics of viral opportunistic infections in immunocompromised population of India The purposes of this study were to determine the frequency of the ... diagnosis of OI is made only on clinical signs and symptoms or when illness is quite advanced, and by then it may be polymicrobial in nature [18,19] Determining the spectrum of OIs and the changing ... related lymphoproliferative disorders and in oral hairy leukoplakia [33] However, only limited information exists on the status of EBV in the course of HIV infection and the extent of its interaction...
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Báo cáo y học: " Persistence of attenuated HIV-1 rev alleles in an epidemiologically linked cohort of long-term survivors infected with nef-deleted virus" ppt
... (NLS) and the RNA-binding domain (RBD) that mediates direct binding of Rev to the RRE, and a highly conserved leucine-rich C-terminal activation domain at aa positions 75 to 83 which contains the ... dividing the signal intensity of bands associated with Rev/RRE complexes by the signal intensity of all bands, and multiplying this number by 100 (B) The data shown are representative of three independent ... of Rev is thought to be more flexible However, a discontinuous epitope of a Revspecific monoclonal antibody was mapped to aa 10 to 20 and 95 to 105 by protein foot printing, suggesting that the...
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Báo cáo y học: " Dimerisation of HIV-2 genomic RNA is linked to efficient RNA packaging, normal particle maturation and viral infectivity" pps
... be interesting to analyse the protein processing of the mutant virus at several time points and determine whether the processing of the Gag and Gag-Pol polyproteins is affected In the mutants of ... end of the dimer band from the beginning of the monomer band and the background in between This is not a problem when analysing a virus that dimerises well, as the very strong intensity of the ... activation of the cassette by the newly synthesised Tat protein and can be detected by measuring GFP production in the infected cells We compared the infectivity of VSV-G pseudotyped wild type and mutant...
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Báo cáo y học: " Isolation of suppressor genes that restore retrovirus susceptibility to a virus-resistant cell line" potx
... restored to a flatter morphology, much closer to that of the parental line, suggesting that the two phenotypes may be causally linked If this notion is correct, changes in the cytoskeleton may ... picked and expanded into larger cultures These cultures were then tested by infection with Eco-GFP, a virus vector expressing the green fluorescent protein, and the fraction of the cells expressing ... MuLV vector carrying the neor marker, and infected cells were selected in medium containing G418 These cultures were then expanded and exposed to Eco-TK virus, an MuLV vector carrying the Herpes...
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Báo cáo y học: "Role of selective V2-receptor-antagonism in septic shock: a randomized, controlled, experimental study" pot
... arginine vasopressin; each group n = AVP, arginine vasopressin; DO2I, oxygen delivery index; Hct, hematocrit; O2-ER, oxygen extraction rate; PaO2/FiO2, ratio of arterial partial pressure of oxygen ... baseline this level in the placebo group during the whole study period The absence of a relative vasopressin deficiency’ may be one reason for the ineffectiveness of AVP in reducing norepinephrine ... infusion of 0.067 U/minute AVP was more effective in restoring MAP and reducing norepinephrine requirements than the recommended low dose of 0.033 U/minute Interestingly, infusion of the selective...
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Báo cáo y học: "Selection of patients with severe pelvic fracture for early angiography remains controversial" ppt
... contributions to conception and design of the study, acquisition of data and analysis and interpretation of data; drafting the article and revising it critically for important intellectual content ... contributions to conception and design of the study, acquisition of data and analysis and interpretation of data; drafting the article and revising it critically for important intellectual content ... evaluation for intra-thoracic and intra-abdominal sources of hemorrhage Pelvic radiography was routinely performed in the trauma bay according to institutional protocol Focused abdominal sonography for...
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Báo cáo y học: "End-of-life decisions in Greek intensive care units: a multicenter cohort study" pot
... [3-12] The frequency of withholding or withdrawal of treatment and the degree of involvement of relatives in the decision making are influenced by the cultural context [13,14] The objective of this ... support and foregoing life-sustaining therapy was driven primarily by an evaluation of objective medical data, mainly the predicted reversibility of the underlying and acute conditions and the unresponsiveness ... support including CPR to patients of group A, or to use every available life-sustaining modality except CPR in patients of group B, were reversibility of illness and prognostic uncertainty; the physician’s...
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Minimum Wages and Employment: A Case Study of the Fast-Food Industry in New Jersey and Pennsylvania pot
... between February and November of 1992 at fast-food stores that were unaffected by the rise in the minimum wage (stores in Pennsylvania and stores in New Jersey paying $5.00 per hour or more in wave ... Another possibility is that employers responded to the increase in the minimum wage by reducing on -the- job training and flattening the tenure-wage profile (see Jacob Mincer and Linda Leighton, ... benefits or their wage profiles to offset the rise in the minimum wage.26 V Price Effects of the Minimum- Wage Increase A final issue we examine is the effect of the minimum wage on the prices of meals...
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Báo cáo Y học: Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues pdf
... specificity of tryptophan residue in the binding of inhibitors to TM-3 This is attributed to the stacking of Trp indole ring against the imidazole side chain of His143 in TM-3 and the specific hydrogen ... characteristics of inhibitor binding The P)1 (binding to S)1 site) Trp residue of the inhibitors As shown in Figs 2A and 3, the indole ring of Trp in the inhibitors, which occupies the S)1 site of TM-3, ... deprotonated in our assay system (pH 8.0) On the other hand, the small Ala residue does not experience steric hinderance for the inhibitor binding to TM-3 The N-terminal pyro-ring of the inhibitor...
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Báo cáo y học: "Management of chest pain: exploring the views and experiences of chiropractors and medical practitioners in a focus group interview"
... one set of themes as reached via consensus This process involved examining themes for commonality, classifying them for uniformity, and then reaching agreement on the final list of six key themes ... the nature of the condition and the urgency of the situation, that the point of referral may depend on the familiarity or relationship between the providers, and that the nature of the referral ... equivalent to medical residencies in family practice They usually require approximately 360 additional hours of didactic training, with only part of that training in a clinical setting There are...
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Báo cáo y học: "Use of chinese and western over-the-counter medications in Hong Kong"
... be the only point of contact when they had minor aliments Therefore, there is a need in promoting and extending the roles of the western medicine community pharmacists in Hong Kong A systematic ... [20] The role of medical professionals is a dominant factor in defining, controlling and scoping the work of the allied health professionals [21,22] as extending pharmacists’ role in primary care ... proximity to other professionals, opportunity for inter-professional communication and access to patients’ medical information are essential to integrate pharmacists in the primary care system...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25