... (infliximab) treatment Cytoplasmic and extracellular expression of HMGB1 decreased in five patients, remained unchanged in one, and increased in three, rendering the authors’ results statistically insignificant ... Taniguchi N, Kawahara K, Yone K, Hashiguchi T, Yamakuchi M, Goto M, Inoue K, Yamada S, Ijiri K, Matsunaga S, Nakajima T, Komiya S, Maruyama I: High mobility group box chromosomal protein plays ... improvement of disease after HMGB1 inhibition implicate HMGB1 asa key mediator and potential therapeutic targetin RA HMGB1 asa novel therapeutic The recent article from Sundberg and colleagues [1]...
... The parameters contained in K are called the intrinsic camera parameters and the six degrees of freedom contained in R and C are called the extrinsic camera parameters CCD cameras The ideal pinhole ... research, we are interested in methods for acquiring, processing, analysing, and understanding images, andin general, highdimensional data from the real world in order to extract semantic information, ... combined image invariants/covariants and geometric relations to organize unordered image sets of multiple non-overlapping scenes for image browsing in 3D Martinec and Pajdla (56) and Sinha et al...
... direct and diffuse radiation Therefore, an alternative model was developed which calculates the distribution of irradiance within the needles, assuming that the attenuation of radiation within decreases ... proposed that a more invariant response of shoot photosynthesis to radiation may be obtained by expressing the radiationin terms of mean irradiance on the needle surface area, which partly eliminates ... unit of intercepted radiation was still clearly higher (Fig A) , indicating that the more even distribution of radiationin the case of diffuse radiation is an important compo- nent, too In the...
... methyltransferase and toward the Ewing sarcoma protein anda peptide Proteins 61, 164–175 48 Raman B, Guarnaccia C, Nadassy K, Zakhariev S, Pintar A, Zanuttin F, Frigyes D, Acatrinei C, Vindigni A, ... material is available: Fig S1 Affinity of RGG3 for binding to a G-quadruplex DNA and RNA Fig S2 CD spectra of DNAs and RNAs Fig S3 Binding affinity of EWS and RBD to Htelo 998 Fig S4 In vitro arginine ... PAGE and visualized by autoradiography acids, was expressed in Escherichia coli as proteins fused to glutathione S-transferase (GST) and purified using glutathione agarose 32P-labeled ETS-1 was...
... pKIMP-UAUC Random gene libraries are introduced into this strain and the ability of a cell harboring an individual library member to form a colony on minimal agar media lacking added phenylalanine and ... constraints, such as packing interactions and polar/nonpolar patterning, on functional sequences Genetic selection of CM libraries has been an invaluable tool in the engineering of drastically ... chorismate mutase–prephenate dehydratase and chorismate mutase–prephenate dehydratase were deleted Monofunctional versions of the dehydratase and the dehydrogenase are provided by plasmid pKIMP-UAUC...
... reproductive tract and bone by using ArKO mice MATERIALS AND METHODS Materials A standard rodent chow (NMF) was obtained from Oriental Yeast (Tokyo, Japan) BPA and E2 were from Sigma-Aldrich An ELISA kit ... BPA was from Takeda Pharmaceutical Co Ltd (Tokyo, Japan) All other chemicals were of analytical grade Animals Animal care and experiments were carried out in accordance with institutional animal ... primer:CGTAAGGC TGTCTCTCATCAAAACT-3¢), bone morphogenetic protein (BMP) 15 (a 1057-bp fragment with sense primer: 5¢-CCCTGGCAAGGAGATGAAGCAATGG-3¢ and antisense primer: 5¢-GGGAAACCTGAGATAGCAACA ACTT-3¢), growth...
... Oregon was categorized asin attainment” for both carbon monoxide and ozone Actual usage of air polluting products such as gas-powered motors and Community-Based Social Marketing asa Planning Tool ... truck, and motorcycle traffic In contrast, nearby regions and the U.S .A Page 36 September/2002 Community-Based Social Marketing asa Planning Tool asa whole have shifted towards increasing use ... students, and community associations The program worked by offering discounted bus passes to individuals who purchased passes as part of a larger group-purchasing program The discount pass acted as an...
... 113 Afghanistan Albania Algeria American Samoa Andorra Angola Anguilla Antigua and Barbuda Argentina Armenia Aruba Australia Austria Azerbaijan Azores Bahamas Bahrain Bangladesh Barbados Belarus ... Belize Benin Bermuda Bhutan Bolivia Bosnia and Herzegovina Botswana Brazil British Virgin Islands Brunei Darussalam Bulgaria Burkina Faso Burundi Cambodia Cameroon Canada Cape Verde Cayman Islands ... 345 Ghana Greece Greenland Grenada Guadeloupe Guam Guatemala Guinea Guinea-Bissau Guyana Haiti Honduras Hong Kong Hungary Iceland India Indonesia Iran Iraq Ireland Isle of Man Israel Italy Ivory...
... P, Ahmad A, Mandal D, Senapati S, Sainkar SR, Khan MI, Ramani R, Parischa R, Kumar PAV, Alam M, Sastry M, Kumar R: Angew Chem Int Ed 2001, 40:3585 14 Ahmad A, Senapati S, Khan MI, Kumar R, Ramani ... Technology, Institute of Technology, Banaras Hindu University, Varanasi 221005, India 3National Facility for Tribal and Herbal Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi ... R, Srinivas V, Sastry M: Nanotechnology 2003, 14:824 15 Gade AK, Bonde PP, Ingle AP, Marcato P, Duran N, Rai MK: J Biobased Mat Bioener 2008, 2:1 16 Vigneshwaran N, Ashtaputre NM, Varadarajan PV,...
... height is a ratio between the stem volume and the diameter at breast height The method of measuring the diameter at a certain height of the tree is also appropriate for the sorting in standing trees ... of the angle gauge (b) b a (a) α borderline Table Average values and their differences Diameter measured optically with wedge prism Diameter measured with calliper Difference Standard deviation ... of the diameter at various heights of stem using the wedge prism asa tool for measurement is a sufficiently accurate method for measurement and can be used for measuring the diameters in the upper...
... with the agents now in use This treatment is especially promising in autoimmune diseases characterized by a relapsing and remitting course such as SLE, inflammatory bowel disease or certain forms ... subset asa possible cause of autoimmune disease J Exp Med 1985, 161:72-87 Kuniyasu Y, Takahashi T, Itoh M, Shimizu J, Toda G, Sakaguchi S: Naturally anergic and suppressive CD25+ CD4+ T cells asa ... No Horwitz et al 36 Heath VL, Murphy EE, Crain C, Tomlinson MG, O’Garra A: TGFbeta1 down-regulates Th2 development and results in decreased IL-4-induced STAT6 activation and GATA-3 expression...
... the total number of γH2AX foci per cell was determined in at least 50 cells Cell Lines and Treatment Mice The MiaPaCa2 (pancreatic adenocarcinoma) and DU145 (prostatic adenocarcinoma) cell lines ... were irradiated with the indicated total body doses A 137Cs Gamma Cell 40 (Nordion International, Kanata, Ontario, Canada) was used as the ionizing radiation source The irradiator was calibrated ... radicals and thus reducing indirect DNA damage Asa measure of radiation- induced DNA damage, we evaluated induction of nuclear foci of phosphorylated histone H2AX (γH2AX), which has been established...
... M6-ANDS was injected to the trans-side and no variation in the ion current occurs As control, maltohexaose was added to the same side (left) The natural substrate is translocated demonstrating ... sugar binding Here we used a modified sugar through covalent binding of an ANDS (3-amino-naphtalene-2,7-disulfonic acid) molecule to the reducing end of a Maltoheptaose as schematically shown in ... membrane facilitates multichannel insertion Membrane current was measured via homemade Ag/AgCl electrodes One electrode was used as ground and the other connected to the headstage of an Axopatch...
... alcohol and drug use and service utilization Participants were asked the quantity and frequency of alcohol, tobacco and drug (prescription and illicit) use as well as current and past alcohol and/ or ... greater population of cannabis users, as medical cannabis patients might differ in substantial ways from the general population, especially concerning areas of substance using behaviour, and patients ... previous alcoholics who have replaced their alcohol use with a daily regimen of cannabis Demographic data were collected as well as information on family alcohol history and alcohol and cannabis usage...
... Rmin was measured again, and then inhalations of albuterol were administered Spirometry and R measurements were repeated 10 minutes after albuterol administration In the sample of nonasthmatics ... acquisition of data, analysis and interpretation of data, and drafting and revising the manuscript SNS contributed to study design, acquisition of data, analysis and interpretation of data, and ... design, acquisition of data, analysis and interpretation of data, and drafting and revising the manuscript All authors read and approved the final manuscript Competing interests The authors declare...
... this was an observational study looking at plasma DNA, a new variable measured from blood samples that were taken as part of standard clinical practice All blood samples were taken from indwelling ... correlation was found between plasma DNA and C-reactive protein, N Terminal-brain natriuretic peptide or procalcitonin Plasma DNA was significantly higher in patients who died in intensive care ... than a combination of neuroimaging techniques and clinical assessment Plasma DNA could not, however, differentiate between cerebral infarction and haemorrhage, suggesting that a wide range of insults...
... Mean (and SEM) of the data of the molecular-biology data set from Figure A: original data B: normalised data C: standardised data D: data after factor correction Note that normalisation, standardisation, ... combination of session and condition Each condition was measured in different sessions In simulating data, the overall mean was set to 100 and the standard deviation was set to 10 Factors and ... Comparison of normalisation, standardisation and factor corComparison of normalisation, standardisation and factor correction DNA constructs containing different enhancer, promoter, and intron...
... thirteen mathematics teachers observed in the classes After observing the actual classes, a meeting was organised in order to share ideas and provide feedback During the meeting, the teachers gave a ... study: a Japanese approach to improving mathematics teaching and learning, Lawrence Erlbaum Associates, Inc, 2004 Foong, P., Y., Open-ended problems for higherorder thinking in mathematics, Teaching ... that comprised four stages: planning → implementing and observing → discussing and reflecting → revising Teaching school mathematics aims to equip students with basic mathematics, and develop and...
... of Shakespeare in Japan, China and Singapore Such a comparative analysis sheds light on the diverse reasons for and approaches to appropriating Shakespeare in Asia, and provides a historical overview ... past and present Asian (intercultural) Shakespeare performances For instance, is there value in naming Asian Shakespeare asa form of intercultural Shakespeare? Does identifying Asian Shakespeare ... creating a digital online archive consisting not only of Shakespeare performances and translated scripts from Asia and Southeast Asia (e.g Japan, Philippines, Korea, China and Singapore) but also...