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forensic report writing and testimony in traumatic brain injury cases

Studies on the mechanisms of the beneficial effects of herba leonuri and leonurine on traumatic brain injury in rat

Studies on the mechanisms of the beneficial effects of herba leonuri and leonurine on traumatic brain injury in rat

Cao đẳng - Đại học

... accelerate at impact, resulting in diffuse brain injury (Foda and Marmarou, 1994; Marmarou et al., 1994) Depending on the severity of injury, the induced brain injury results in hemorrhages, neuronal ... al., 2008) In the traumatically injured brain, the temporal and spatial distribution of apoptosis is highly dependent on the type and severity of injury In both experimental brain injury and human ... brain injuries close to the clinical conditions ranging from focal to diffuse brain injuries 1.1.3.2 Fluid percussion injury (FPI) models FPI models produce brain injury by rapidly injecting...
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báo cáo hóa học:

báo cáo hóa học: " Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice" pot

Hóa học - Dầu khí

... (in 0.1% milk in PBS containing 0.05% TWEEN) and murine recombinant mouse C5a at defined concentrations for establishing the standard curve After incubation and subsequent washing steps, biotinylated ... JW, Stover JF, McIntosh TK: Pharmacology of traumatic brain injury Curr Opin Pharmacol 2003, 3(1):27-32 Doppenberg EM, Choi SC, Bullock R: Clinical trials in traumatic brain injury: lessons for ... extracted from homogenized murine brains at hours, 24 hours, and days after traumatic brain injury (TBI) The murine primers for GAPDH, Bcl-2, Fas and C1-Inh are depicted in table The technique for...
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Báo cáo y học:

Báo cáo y học: "rogesterone in traumatic brain injury: time to move on to phase III trials" doc

Báo cáo khoa học

... injuries [6-8] Competing interests SMM is an investigator in the Traumatic Brain Injury Clinical Trials Network JDK is a Principal Investigator in the Resuscitation Outcomes Consortium References Xiao ... Neuroprotection in traumatic brain injury: a complex struggle against the nature of biology Curr Opin Crit Care 2007, 13:134-142 Wang KK, Larner SF, Robinson G, Hayes RL: Neuroprotection targets after traumatic ... preclinical promise to clinical reality are vital to those of us seeking to expand our armamentarium of therapeutic options in the treatment of these injuries [6-8] Competing interests SMM is an investigator...
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Báo cáo y học:

Báo cáo y học: " Intensive glycemic control in traumatic brain injury: what is the ideal glucose range" pps

Báo cáo khoa học

... Hyperglycemia and brain tissue pH after traumatic brain injury Neurosurgery 2004, 55:877-881 12 Bilotta F, Spinelli A, Giovannini F, Doronzio A, Delfini R, Rosa G: The effect of intensive insulin therapy ... to mmol/l) in patients with severe traumatic brain injury Crit Care 2008, 12:R98 Lam AM, Winn HR, Cullen BF, Sundling N: Hyperglycemia and neurological outcome in patients with head injury J Neurosurg ... pressure profile during the second week after injury in the intensive control group, the preponderance of data points against the use of intensive glycemic control This finding stands in sharp contrast...
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Báo cáo y học:

Báo cáo y học: "Standardisation of data collection in traumatic brain injury: key to the future" pot

Báo cáo khoa học

... of standardization were integrated in the US into a much larger interagency initiative towards ‘an integrated approach to research in psychological health and traumatic brain injury This initiative ... towards ‘an integrated approach to research in Psychological Health and Traumatic Brain Injury References Maas AIR, Stocchetti N, Bullock R: Moderate and severe traumatic brain injury in adults ... Steyerberg EW: Prognosis and clinical trial design in traumatic brain injury: the IMPACT study J Neurotrauma 2007, 24:232-238 Brain Trauma Foundation [http://www.braintrauma.org/site/ PageServer]...
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Báo cáo y học:

Báo cáo y học: "Bench-to-bedside review: Hypothermia in traumatic brain injury" pot

Báo cáo khoa học

... HQ, Jenkins LW, Marion DW, Dixon CE: Acute systemic administration of interleukin-10 suppresses the beneficial effects of moderate hypothermia following traumatic brain injury in rats Brain Res ... global ischemia Brain Res Mol Brain Res 2001, 86:34-47 33 Lyeth BG, Jiang JY, Robinson SE, Guo H, Jenkins LW: Hypothermia blunts acetylcholine increase in CSF of traumatically brain injured rats ... alpha expression and protein levels after fluid percussion injury in rats: the effect of injury severity and brain temperature Neurosurgery 2004, 55:416-424 21 Kline AE, Bolinger BD, Kochanek...
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Báo cáo y học:

Báo cáo y học: "The added value of ordinal analysis in clinical trials: an example in traumatic brain injury" potx

Báo cáo khoa học

... simulation study evaluating approaches to the analysis of ordinal outcome data in randomized controlled trials in traumatic brain injury: results from the IMPACT Project Clin Trials 2010, 7:44-57 ... N, Knoller N, Pharmos TBI investigators: Efficacy and safety of dexanabinol in severe traumatic brain injury: results of a phase III randomised, placebo-controlled, clinical trial Lancet Neurol ... improving the design and analysis of clinical trials in moderate to severe traumatic brain injury Neurotherapeutics 2010, 7:127-134 McHugh GS, Butcher I, Steyerberg EW, Marmarou A, Lu J, Lingsma...
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Automatic annotation, classification and retrieval of traumatic brain injury CT images

Automatic annotation, classification and retrieval of traumatic brain injury CT images

Cao đẳng - Đại học

... distribution in testing reports 72 3.2 Evaluation result for medical findings in brain CT radiology reports 73 3.3 Evaluation result for modifiers of the medical findings in brain CT radiology reports ... This is compressing the underlying brain and distorting the left lateral ventricle Figure 1.2: The radiology report associated with the CT image series 15 For traumatic brain injury, CT is a ... skull results in compression injury to the adjacent brain (coup) and stretching on the opposite side (contrecoup) This may result in contusion, shearing injuries and rupture of intra-axial or...
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Cognitive rehabilitation of attention deficits in traumatic brain injury using action video games: A controlled trial

Cognitive rehabilitation of attention deficits in traumatic brain injury using action video games: A controlled trial

Tổng hợp

... McLaughlin, K A., Pavese, A., Heidrich, A., & Posner, M I (2000) Evaluation of attention process training and brain injury education in persons with acquired brain injury Journal of Clinical and ... demographics The following demographic information was taken: age at injury (in years), age at first assessment (in years), time since injury (in months), days of post -traumatic amnesia (PTA) and years of ... for TBI incorporating action video gaming and psycho-education Participants in the attention-training condition showed significant improvements in game performance (shooting accuracy and the...
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báo cáo hóa học:

báo cáo hóa học: " Post-traumatic hypoxia exacerbates neurological deficit, neuroinflammation and cerebral metabolism in rats with diffuse traumatic brain injury" pptx

Toán học

... Post -Injury (hours) E * D Brain IL-2 (pg/mg protein) Brain TNF (pg/mg protein) B Time Post -Injury (hours) C Brain IL-4 (pg/mg protein) * Brain IL-1 (pg/mg protein) Brain IL-6 (pg/mg protein) A Page of 16 ... Moderate and severe traumatic brain injury in adults Lancet Neurol 2008, 7:728-741 Gaetz M: The neurophysiology of brain injury Clin Neurophysiol 2004, 115:4-18 Masel BE, DeWitt DS: Traumatic brain injury: ... Post -Injury (hours) Figure Increase in brain edema does not differ in traumatic axonal injury rats with or without hypoxia Brain water content was determined at 2, 24, 48, 72 and 96 h post -injury, ...
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Traumatic brain injury and the effects of diazepam, diltiazem, and MK-801 on GABA-A receptor subunit expression in rat hippocampus ppt

Traumatic brain injury and the effects of diazepam, diltiazem, and MK-801 on GABA-A receptor subunit expression in rat hippocampus ppt

Báo cáo khoa học

... in an incomplete understanding of their contribution to injury- induced pathology, but have indicated that the receptor is affected by injury Sihver et al [12] found a decrease in GABAAR binding ... the injuryinduced decrease in expression (M = 74.93) [F(3,9) = 14.907, p < 01], indicating DZ decreased α3 expression, regardless of injury condition DZ normalized γ2 injuryinduced decreases in ... phosphorylation of subunit proteins Increases in glutamate after injury trigger VGCC and NMDA receptors, increasing [Ca2+]i, and resulting in activation of CaMKII A single dose of DZ can downregulate...
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Báo cáo y học:

Báo cáo y học: "Stimulation dependent induction of fear and depression in deep brain stimulation: a case report" docx

Báo cáo khoa học

... MS and IU performed postoperative video documentation during reprogramming IU performed all pre- and postoperative neuropsychological examinations and tests and interpreted these MS and AS finalized ... competing interests Authors’ contributions MS and AS performed intraoperative micro-recording, macro-stimulation and functional testing KS performed the surgical procedure and the trajectory planning ... Targeting the basal ganglia for deep brain stimulation in Parkinson’s disease Neurology 2000, 55:S21-S28 Richter EO, Hoque T, Halliday W, Lozano AM, Saint-Cyr JA: Determining the position and size...
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Báo cáo y học:

Báo cáo y học: "In vitro norepinephrine significantly activates isolated platelets from healthy volunteers and critically ill patients following severe traumatic brain injury" pptx

Báo cáo khoa học

... less than 2% severe traumatic brain of surface P-selectin in with healthy controls Changes in expressioninjury patients comparedplatelets isolated from severe traumatic brain injury patients compared ... Relative increases in norepinephrine-induced expression of P-selectin in arterial (blackhealthy controls (white bars) expressed as a percentage of severe traumatic brain injury (TBI) patients and ... percentage of baseline values Baseline values were determined in platelets not stimulated in vitro with norepinephrine During the first week, the norepinephrinemediated increase in P-selectin-positive...
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Báo cáo y học:

Báo cáo y học: "The relation between the incidence of hypernatremia and mortality in patients with severe traumatic brain injury" pptx

Báo cáo khoa học

... severe brain injury Curr Opin Clin Nutr Metab Care 2008, 11:134-139 Schneider HJ, Kreitschmann-Andermahar I, Ghigo E, Stalla GK, Agha A: Hypothalamopituitary dysfunction following traumatic brain injury ... admitted (in fact, missing urine output was significantly and independently associated with increased mortality; data not shown) In some other cases, exact urine output recording was missing during ... saline [54] In that study, hypertonic saline use increased the risk of hypernatremia, increased the number of infection days, increased the hospital length of stay, increased the creatinine and...
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Báo cáo y học:

Báo cáo y học: "Argon: Neuroprotection in in vitro models of cerebral ischemia and traumatic brain injury" pdf

Báo cáo khoa học

... Liquide Santé International, Paris, France) Traumatic brain injury All slices subject to traumatic brain injury were first incubated for 30 minutes at 37°C, 95% air and 5% CO2 in EM containing 4.5 ... McIntosh TK: Apoptosis after traumatic brain injury J Neurotrauma 2000, 17:927-938 Faden AI: Neuroprotection and traumatic brain injury: theoretical option or realistic proposition Curr Opin ... before by us and others when testing possible treatments [8,19,25] for traumatic brain injury Nevertheless this is a simplified imitation of brain trauma, which lacks pathomechanisms involving systemic...
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Báo cáo y học:

Báo cáo y học: "Brain metabolism is significantly impaired at blood glucose below 6 mM and brain glucose below 1 mM in patients with severe traumatic brain injury" pptx

Báo cáo khoa học

... be insulin-dependent because insulin administration was associated with significantly increased interstitial brain glucose This is in line with the findings of insulin-mediated increases in mean ... pre-defined criteria in terms of glucose level and insulin dose are required to interpret the present findings and to define safe brain- glucose dependent insulin dose Influence of insulin on cerebral ... increases in brain glutamate at low brain glucose levels below mM compared with episodes in which insulin was not administered At brain glucose levels above mM, administered insulin did not influence...
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Báo cáo y học:

Báo cáo y học: "Acute and delayed mild coagulopathy are related to outcome in patients with isolated traumatic brain injury" docx

Báo cáo khoa học

... disorders in patients with isolated head injury Although data regarding blood transfusion in early and late coagulopathy in traumatic brain injury are limited, an increasing number of investigations ... coagulopathy in isolated traumatic brain injury may contribute to improved patient outcome • Coagulation measurements in severe isolated traumatic brain injury should be frequently performed and continued ... isolated traumatic brain injury is at risk for the development of coagulopathy • The number of patients with isolated traumatic brain injury and coagulopathy doubles within 72 hours post-trauma and...
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cognitive function and traumatic brain injury in refugees and asylum-seekers attending mental health services a preliminary study ; and clinical research portfolio

cognitive function and traumatic brain injury in refugees and asylum-seekers attending mental health services a preliminary study ; and clinical research portfolio

Tổng hợp

... Cognitive function and traumatic brain injury in refugees and asylumseekers attending mental health services – a preliminary study And Clinical Research Portfolio Volume (Volume ... function and traumatic brain injury in refugees and asylum-seekers attending mental health services – a preliminary study Plain English Summary 38 Abstract 39 Introduction ... function and traumatic brain injury in refugees and asylumseekers attending mental health services – a preliminary study Zara Christie1 Address for Correspondence: Mental Health and Wellbeing University...
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The relationship of psychological and personality factors to post concussive symptoms (PCS) in mild traumatic brain injury (MTBI) patients

The relationship of psychological and personality factors to post concussive symptoms (PCS) in mild traumatic brain injury (MTBI) patients

Kỹ thuật - Công nghệ

... Ng, 2006) 1.1 Defining And Diagnosing Mild Traumatic Brain Injury (MTBI) Mild traumatic brain injury (MTBI) is the least severe in the spectrum of traumatic brain injury (Stein, 1996) Recent ... 1.1 1.2 1.3 1.4 DEFINING AND DIAGNOSING MILD TRAUMATIC BRAIN INJURY (MTBI) EPIDEMIOLOGY AND CAUSES OF MILD TRAUMATIC BRAIN INJURY (MTBI) COURSE AND OUTCOME OF MTBI ... increase in our understanding of problems surrounding PCS and PPCS From a definition and diagnostic point of view, there remains much to be examined in establishing consistent terminologies and...
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Báo cáo y học:

Báo cáo y học: "Technical Considerations in Decompressive Craniectomy in the Treatment of Traumatic Brain Injury"

Y học thưởng thức

... traumatic brain injury Injury 2006;37:1125-1132 Coplin WM Intracranial pressure and surgical decompression for traumatic brain injury: biological rationale and protocol for a randomized clinical ... Surgeons The Joint Section on Neurotrauma and Critical Care Management and prognosis of severe traumatic brain injury, part 1: Guidelines for the management of severe traumatic brain injury J Neurotrauma ... vessels supporting the portion of brain run in the artificial “vascular tunnel” between the brain tissue and dura Finally, the dura was closed as in augmentation duraplasty In the latest report, they...
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