flow lymphatics and binding as determinants of topical absorption clearance and distribution
COLLATERAL, TYPE OF LENDER AND RELATIONSHIP BANKING AS DETERMINANTS OF CREDIT RISK pptx
... transformation of that constant gives the PD of a loan with the same characteristics as those of the excluded loan 12 The goodness of fit measure is based on the association of predicted probabilities and ... Y S and G KANATAS (1985) Asymmetric Valuation and the Role of Collateral in Loan Agreements, Journal of Money, Credit and Banking, 17, pp 85-95 CHAN, Y S and A V THAKOR (1987) Collateral and ... coverage of the loan This type of collateral may take the form of public bonds, cash deposits, property or shipping mortgages, listed shares, merchandise or receipts of deposit of merchandise More...
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Genome wide meta analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption
... beneficial and toxic effects of caffeine as well as the extensive group of carcinogens, drugs, and xenobiotics also metabolized through action of the regulation of the gene products of CYP1A2 and AHR ... of caffeine was 137 mg per cup of coffee, 47 mg per cup of tea, 46 mg per can or bottle of cola or other caffeinated carbonated beverage, and mg per oz serving of chocolate candy We assessed the ... dietary recalls [26] and asks about consumption frequency of 124 food items over the past 12 months, including the primary sources of caffeine: coffee, tea, and soft drinks For soft drinks, participants...
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Tài liệu Báo cáo khoa học: Molecular determinants of ligand specificity in family 11 carbohydrate binding modules – an NMR, X-ray crystallography and computational chemistry approach doc
... Asp128 and Asp146 amino acids and, in the case of the larger ligands, with Asp51 as well Most of the hydrogen bonds occur via the hydroxyl groups associated with the C2 and C6 carbon atoms of each ... amino acids Asp99, Arg126, Asp128 and Asp146 and, in the case of the larger ligands, with Asp51 It is important to emphasize that most of the hydrogen bonds occur via the hydroxyl groups associated ... use of as little as nmol of protein with a molecular mass > 10 kDa [16,18,21] STD-NMR spectroscopy was used to analyze the binding of cellohexaose to CtCBM11 The STD-NMR spectrum of the hexasaccharide...
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Tài liệu Báo cáo khoa học: Diversity and junction residues as hotspots of binding energy in an antibody neutralizing the dengue virus doc
... constants kon and koff were measured at 25 °C with the Biacore instrument, with MalE–E3-H6 in the immobile phase and Fab4E11H6 in the mobile phase The mean and associated SE values of koff in measurements ... interface between a solid and a liquid phase, and calculated as the ratio of two rate constants However, values of DDG and DDG¢ for mutant Fab fragments, calculated from values of KD and KD¢, respectively ... (sc-ASA) of the wild-type residue in column 1, as measured in a three-dimensional model of Fv4E11 (see Fig 4) Column 5, variation DDG of the free energy of interaction between Fab4E11-H6 and...
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Identifying determinants of background matching and disruptive colouration using computer simulations and humans as predators
... base of X and a height of X, where X is a random number from a normal distribution with standard deviation of 1.5 pixels (px; px is approximately 0.3 × 0.3mm on screen) Eight element size classes ... defined as “a set of markings that creates the appearance of false edges and boundaries and hinders the detection or recognition of an object’s, or part of an object’s, true outline and shape.” ... density of elements on prey and background is also tested in a parallel experiment (Chapter 3) In both cases, model prey consisted of extremes, i.e high and low contrast elements, and high and low...
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Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"
... Fluorescence emission was recorded at 460 and 580 nm After a 20 sec baseline reading, 0.1 ml of PBS containing 10 µM of the compound investigated was added, and the fluorescence signal was recorder for ... biosynthesis of chrysomelidial and salicin These substances are synthesized and secreted as part of a defense mechanism used by larvae of beetles (Chrysomelidae) Their synthesis has been previously ... (A) and CHO cells expressing hSGLT2 (B) was determined by IC50 assessment Different concentrations of thioglycoside I and VII in log scale were plotted against [14C]AMG uptake as percentage of...
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Foreign direct investment in Vietnam: An overview and analysis the determinants of spatial distribution across provinces
... Delta North East North East West East West East North Central Coast North Central Coast South Central Coast South Central Coast Central Highland Central Highland South East South East Mekong River ... determinants of FDI and its impacts on the economy of Vietnam Our regression analysis of the determinants of FDI spatial distribution across provinces points to the importance of market, labour and infrastructure ... FDI inflows since the inception of economic reform in 1986 The inflow of FDI has contributed significantly to the economic development of Vietnam Still, the determinants of FDI inflow and its...
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Tài liệu Transformation through Integration An Activity Theoretical Analysis of School Development as Integration of Child Care Institutions and the Elementary School ppt
... schoolchildren of working or studying parents, or in cases where the child has an individual need A place should be offered as close to the child’s home as possible As in the case of pre-school and family ... Swedish school system has gone through phases of change, as accounted for above, it seems that transmission of basic skills and knowledge remains the main mission However, and as the account shows, ... content, and methods in three integrated groups are compared and analyzed The analysis is based on staff and parent understanding and evaluation of methods and content The data consists of interviews,...
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Tài liệu Báo cáo " DETERMINING FLOW ENERGY AND EROSION COEFFICIENT FOR CLASSIFICATION OF POTENTIAL EROSION IN BINH DINH PROVINCE " ppt
... 200-700 and has area of 25,669 hectares (28.3% of the convertible land) This group has high centralization level of the convertible land and high erosion potential level VNU Journal of Science, ... potential: consists of soil with erosion potential M
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Tài liệu Báo cáo khoa học: Secondary substrate binding strongly affects activity and binding affinity of Bacillus subtilis and Aspergillus niger GH11 xylanases docx
... the secondary binding sites of the A niger xylanase (A) and the B subtilis xylanase (B) The diagrams of protein–ligand interactions were generated using LIGPLOT [37] based on Vandermarliere et ... substrate binding in GH11 xylanases Table The effect of genetic engineering of the secondary binding site of the B subtilis and A niger xylanases on the screening ratio The screening ratio is defined as ... substrate binding is closely linked to activity Therefore, the binding of the different XBS and XAN mutants towards water-unextractable AX and OSX was assessed by constructing binding curves, as shown...
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Tài liệu Determinants of Productivity for Military Personnel - A Review of Findings on the Contribution of Experience, Training, and Aptitude to Military Performance pdf
... of excellent landings by 2.5 percentage points and increasing the number of unsatisfactory landings by 2.6 percentage points On the other hand, a career decrease of 10 percent in the number of ... hours of 10 percent led to a 10 percent increase in the number of unsatisfactory landings, from 14 percent to 24 percent of the total, and a percent decrease in the number of excellent landings, ... personnel must also handle large amounts of paperwork and complete other administrative tasks The result of all of these demands on personnel time is that senior members of the force are often in short...
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Tài liệu Báo cáo Y học: Structural determinants of the half-life and cleavage site preference in the autolytic inactivation of chymotrypsin pdf
... cleavages of the sites were in the order: Tyr146/Asn147 ! Phe114 ! other sites The weakness of bands of fragments I and IV and the appearance of fragment II in the degradation of the Tyr146 !His/Asn147 ... autolysis loop was indeed cleaved at Asn147; the Tyr146 !Ser/Asn147 !Asp autolysis loop mutant had exactly the same molecular, enzymatic and autolytic properties as the Tyr146 !His/Asn147 !Ser mutant ... which was linear with time and remained just below the level of detection (less than 2%) after days sites 138 and 172, as well as at 15 other sites in two surface loops next to the substrate binding...
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AESTHETIC AS SCIENCE OF EXPRESSION AND GENERAL LINGUISTIC docx
... quite as independent of Hegel as of Kant, of Vico as of Spinoza Of course he has made use of the best of Hegel, just as every thinker makes use of his predecessors and is in his turn made use of ... verisimilar and of naturalism–Critique of ideas in art, of art as thesis, and of the typical–Critique of the symbol and of the allegory–Critique of the theory of artistic and literary categories–Errors ... else The doctrine of the concept and of the organism of the concepts, of definition, of system, of philosophy, and of the various sciences, and the like, will fill the place of these and will constitute...
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Báo cáo khoa học: Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast docx
... expressed Hsp82 and Sba1p of yeast Hsp90 ATPase assays Hsp90 ATPase assays used a regeneration coupled enzyme assay [24], each mL of assay using lM of purified recombinant Hsp82 as described previously ... Hsp82, Fig GA and Sti1p inhibition of the intrinsic ATPase of purified wildtype and A587T mutant Hsp82 Assays were conducted at 37 °C as described previously [33], using lM Hsp82 protein and either ... or T101I and A587T mutant forms of Hsp82 Basal and heat-induced (1 h 39 °C) HSE-LacZ activity (open and solid bars, respectively) was determined both in the absence (–) and presence (+) of lM RD...
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Báo cáo khoa học: Halogenated benzimidazoles and benzotriazoles as inhibitors of the NTPase/helicase activities of hepatitis C and related viruses ppt
... properties of TBBT, and a number of related benzotriazoles and benzimidazoles, at the NTPase/helicase sites of HCV and the related viruses Japanese encephalitis virus (JEV) and WNV, as well as the ... masses of 66 and 60 kDa N-terminal sequencing allowed the identification of these proteins as BSA and WNV NTPase/helicase (Fig 1, lane 2) [20] Protein concentrations of preparations of the NTPase/ ... molecular ATPase activity of the NTPase/helicases was determined as described previously [17,19,20] Briefly, assays were performed with pmol of WNV, 0.5 pmol of HCV, pmol of JEV or 0.2 pmol of Suv3(D1–159)...
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Aesthetic as Science of Expression and General Linguistic doc
... absence of style, of objective and subjective, of classic and romantic, of simple and ornate, of proper and metaphorical, of the fourteen forms of metaphor, of the figures of word and of sentence, and ... quite as independent of Hegel as of Kant, of Vico as of Spinoza Of course he has made use of the best of Hegel, just as every thinker makes use of his predecessors and is in his turn made use of ... HISTORICISM AND INTELLECTUALISM IN AESTHETIC Critique of the verisimilar and of naturalism Critique of ideas in art, of art as thesis, and of the typical Critique of the symbol and of the allegory...
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Báo cáo Y học: Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues pdf
... pockets of adamalysin II (cyan) and atrolysin C (blue) after the binding of a phosphonate inhibitor and the batimastat, respectively [26,47] (E) and (F), the S)1 pockets of the catalytic proteinase ... different snake species The P)2 Asn, Gln and Lys residues of the inhibitors As shown in Fig 5, the Asn, Gln and Lys residues of the inhibitors are stabilized at the S)2 site of TM-3 by three possible ... S)1 and S)2 sites of atrolysin C, close to the position of the Asn side chain of pENW in our structure (compare Fig 6B with A) The isobutyl group of batimastat is directed toward the S)3 site of...
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Determinants of commercial bank interest margins and profitability: some international evidence ppt
... over total assets, or before tax profit/ta By s straightforward accounting, before tax profit/ta is the sum of after-tax profits over total assets, or net profit/ta, and taxes over total assets, ... concentration ratio, number of banks and the bank’ s total assets, as indicators of market structure and scale effects Various authors, such as Gilbert (1984), Berger (1995), and Goldberg and Rai (1996), ... between capitalization and profitability, and a negative relationship between reserves and profitability Other important determinants of bank margins and profitability, such as ownership, corporate...
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ECOLOGY OF COLD SEEP SEDIMENTS: INTERACTIONS OF FAUNA WITH FLOW, CHEMISTRY AND MICROBES potx
... surface and the high supply of methane leads to higher rates of Anaerobic Oxidation of Methane (AOM) in surface sediments For gas-hydrate bearing sediments on Hydrate Ridge off the coast of Oregon ... amphipods (Orchomene and Stephonyx sp.) and sipunculans (Phalascosoma) Densities of many taxa increase with habitat complexity, measured as tubeworm density, but decline with age of the tubeworm aggregation ... microscopic studies and molecular sequencing of symbionts Both methane-based and sulphur-based symbioses fuel much of the consumer biomass at seeps via tubeworms, mussels and clams Vesicomyid...
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Concentration and distribution of extractable elements in soil as affected by tillage systems and fertil
... hypothesize that concentrations of trace elements will increase and stratify in those soils However, as a consequence of the recent introduction of zero tillage and the lack of fertilization history, ... ppm pH Exchang Cab Exchang Mg Exchang K Extract Al ppm ZT CT Past ZT CT Past ZT CT Past ZT CT Past ZT CT Past ZT CT Past ZT CT Past 5᎐10 10᎐15 15᎐20 3.87 bA 2.70 cA 6.60 aA 17.67 aA 21.50 aA ... distribution in depth of arsenic, copper, iron, lead and manganese Žmgrkg a Element Treatment Depth Žcm 0᎐5 As ZT CT Past ZT CT Past ZT CT Past ZT CT Past ZT CT Past Pb Cu Fe Mn 5᎐10 10᎐15 15᎐20 0.058 aA...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25