factors defining peak capacity in chromatographic separations a peak capacity in single dimension chromatographic systems is defined by the number of components i e peptides than can be separated in a given separation space in thi
... treated with HSD, which has been shown previously to induce an increase inthe level of [Ca2+ ]i and a correlated calpain activation [28] This increase in [Ca2+ ]i is more intense in aorta thanin ... produced by active calpain [32], these observations further indicate that calpain is activated in both tissues, although at a higher rate in aorta Further direct evidence in support of calpain activation ... rats were also used, as a limited increase in [Ca2+ ]i in both aorta and brain has been found to be constitutively present in these animals To assess thein vivo activation of calpain, we relied...
... and cofactors to verify this hypothesis The present work has indicated that metabolic engineering canbe effectively used to enhance 1, 3-PD productivity in L reuteri Further engineering ofthe ... formation of lactate and ethanol were higher and that of acetate lower inthe recombinant culture, relative to the native strain, during the second half ofthe logarithmic phase (Figure 5) The batch ... peer review Immediate publication on acceptance Open access: articles freely available online High visibility within the field Retaining the copyright to your article Submit your next manuscript...
... where the initial discovery or the first Phase I trial was carried out by Cancer Research UK Of these, between six and nine will bein Phase III development, including anumberof potential treatments ... further and increase capacityin imaging research and in more sophisticated in silico and mouse models of disease • Promote clinical and translational research which will maximise cancer survival ... make informed choices that will reduce their risk of cancer, increase their chances of early detection, understand their cancer and make appropriate treatment decisions Information is an integral...
... metabolic engineering of freezing tolerance in plants should include such an analysis ofthe dynamics of metabolism to gain comprehensive information about the effects of individual overexpression ... Arabid¨ opsis leaves developing at low temperatures Increasing cytoplasmic volume accompanies increased activities of enzymes inthe Calvin cycle and inthe sucrose-biosynthesis pathway Plant ... continuous lines) To test the statistical robustness ofthe identified model parameters and to validate them with experimental data, 50 independent identification processes with varying initial carbohydrate...
... determines the specific recognition ofthe sequence (GGAA/T) However, sequences immediately flanking this core element determine the recognition of target sites in different genes In addition promoter ... mRNAs results from alternative initiation site(s) at exon rather than alternative splicing [32] Such flexibility inthe mechanism of initiation presents several advantages First it is consistent ... cellular context The specificity of Ets factorsis determined by their site of expression, their selective target sequence recognition, their selective abilities to interact with other transcription...
... relationship between regional visual impairment rates and indicators of other eye-care activities, such as numberof visits/inhabitant, glaucoma diagnosis campaign, etc Inequality of quality of care could ... diseases leading to blindness in Western developed countries Apart from cataract surgery, treatments are available which at best maintain vision, or otherwise postpone visual acuity deterioration ... International Statistical Classification of Diseases, Injuries and Causes of Death, visual impairment includes both low vision and blindness Low vision isdefined as visual acuity less than 6/18,...
... componentsThe closer they are, the larger isthe dynamic range ∆λ1 The eigenvalue variation is not necessarily linear, but the results obtained in this case canbe generalized This type of variation ... function issued from their difference allows quite satisfactorily the estimation of N PARTICULAR CASE OFA LINEAR PIECEWISE VARIATION OFTHE AUTOCORRELATION MATRIX EIGENVALUES The theoretical validity ... to detect directly this jump inthe case of noisy signals However, it canbe noticed that even for these signals there isa slope variation between the two classes of eigenvalues The main idea...
... electronic journal of combinatorics (2001), #N9 Acknowledgment The author thanks Prof Yair Caro and Raphael Yuster for sending reference [7] The author also thanks Prof Cheng Zhao for his advice References ... numberof vertices, and (G) denote thenumberof edges In this paper, we construct a graph G having no two cycles with the same length which leads to the following result Theorem Let t = 27720r ... ≤ i ≤ 30t + 60, and 31t − 738 ≤ i ≤ 31t + 799) Now we define these Bi ’s These subgraphs all have a common vertex x, otherwise their vertex sets are pairwise disjoint For 7t+1 ≤ i ≤ t − 742, let...
... even if the graph is very dense, the extreme case being an acyclic orientation ofa complete bipartite graph) The most interesting and natural constraint isthe requirement that the digraph be ... mentioning that in Theorem 1.1, if v is any vertex with maximum normalized degree (by “normalized degree” we mean the ratio between its outdegree and the cardinality ofthe opposite vertex class), ... digraph be Eulerian, namely, the indegree ofa vertex must be equal to its outdegree Let b(m, n) denote the maximum integer, such that there exists an Eulerian bipartite digraph with vertex partition...
... special case where m = 0; in this case the path Q isa path on vertices, and R = P satisfies the lemma trivially The remainder ofthe proof isby induction on m For m = 1, let ibethe minimal index ... paths that include the arc → v1 , and there isa unique hamiltonian path of T that avoids this arc Hence, there are 2n−2 + distinct hamiltonian paths ina nearly transitive tournament of order ... v In both cases, this implies that T is nearly transitive Our next lemma is probably widely known The proof is an easy inductive extension ofthe well known fact that ina tournament, every vertex...
... commute with mutation of triangulations Mutating a triangulation at agiven diagonal is defined as removing this diagonal and replacing it with another one to obtain a new triangulation This canbe done ... C (i) canbe defined as thenumberof triangulations of an i+ 2-gon with i − diagonals It isgivenby C (i) = 2i i+ 1 iThenumberof equivalence classes inthe mutation class of any quiver of type ... we can define a quiver with n vertices inthe following way The vertices are the midpoints ofthe diagonals There is an arrow between i and j if the corresponding diagonals bound a common triangle...
... to thenumberof matchings ina graph This is also known as the Hosoya index, or the Z-index in mathematical chemistry For a rooted tree T , let Z(T ) bethenumberof matchings and Z0 (T ) be ... An interesting paper of Wagner [5] looks at thenumberof independent sets modulo m Wagner showed that the proportion of trees on n vertices with thenumberof independent sets divisible by ... b) The sequence m m µk (a, b) : k ∈ N must contain repeated elements since Z2 is finite But once it repeats, m the sequence becomes periodic Moreover, as µ is invertible with µ−1 (a, b) = (b − a, ...
... Several parts ofthe proofs are computer aided, both for searching the strong words (the main concept inthe proofs) as well as for checking their compatibilities We have included the Mathematica ... isa strong word, then so is its complement w obtained from w by ¯ interchanging the letters and Example The short strong words, beginning with 0, are listed in Table As an example consider the ... Lothaire Combinatorics on words Cambridge Mathematical Library Cambridge University Press, Cambridge, 1997 [7] P Ochem and M Rao Minimum frequencies of occurrences of squares and letters in infinite...
... this is indeed the inverse ofthe mapping described above Notice that vertices that are not ina cycle are left bythe Joyal mapping as they were in Gf , meaning that they will be incident with ... previous results regarding thenumberof independent sets in trees Another graph parameter popular in statistical physics and in mathematical chemistry isthe Hosoya index which isthenumberof ... F -matchings inagiven class Ci is precisely thenumberof F -matchings inthe forest remaining from T after removing v and the copy covering it, if there is one In fact, this numberisthe product...
... This raises the problem of determining the smallest positive integer ℓ such that every sequence S of length at least ℓ has a nonempty zero-sum subsequence Such an integer ℓ is called the Davenport ... briefly gather some notions and fix the notation concerning sequences over abelian group Let N and N0 denote the sets of positive integers and non-negative integers, respectively For integers a, ... done Now assume |S| ≥ D(G) + If all the minimal zero-sum subsequences of S are pairwise disjoint, then the conclusion follows readily So we may assume that there exist two distinct minimal zero-sum...
... tuberculosis and pressure ulcer KH participated inthe assessment ofthe patient’s clinical data MS supervised the treatment of tuberculosis and revised the manuscript for important intellectual ... is required [9] The manufacturer ofthe nutrition we used for this patient recommends that the administration ofthe semi-solid nutrition be done in 15 minutes Administration should be carried ... designed the nutrition treatment plan ofthe patient SH supervised the nutrition treatment plan, wrote the manuscript, and reviewed the international literature KO, TT and EN treated the patient’s...
... the association restricted to male would be performed We did not validate the association between the SNPs ofthe IL-8 gene in an independent replication population We evaluate the effect ofthe ... Perkinelmer, Waltham, MA, USA) And the relative luciferase activity was normalized to the protein concentration and b-galactosidase activity Statistics We applied widely used measures of linkage disequilibrium ... contribution to the pathogenesis of IPF Additional material Additional file 1: The fluorescence labeled allelic probe for amplification of IL8, IL8RA and IL8RB genes The data provided represent the...
... which the measures will be taken is defined; in this case a geometric centroid of an administrative unit (census collector district, the smallest administrative spatial unit in Australia) is calculated ... to GIS, however the advantage of GIS is that many plausible scales might be investigated Measurement Activity space An activity space represents all locations visited by an individual within a ... locality because these data were readily available These measures assume equal exposure for each person within the area unit irrespective of where they live in that unit, the amount of time that...
... isa power parameter The power parameter was estimated jointly with the other parameters in ML analyses, whereas the data were transformed before being analysed for genetic parameter estimation ... analysed Indeed, most ofthe genetic information contained inthe pedigree concerned the segregation of genes within half-sib families They probably cannot be extended to the case of pedigrees ... dependencies between families [13] because animal pedigrees generally contain many loops due to the use of multiple matings All relationships within a pedigree can now be taken into account using a...
... possible to envisage management measures aiming to reduce incidence of dark fibres If an intrinsic 392 H Naya et al ageing process isthe main factor, reducing the age at shearing could bea practice ... take into consideration This requires additional research In an animal breeding context, genetic and environmental variances are extremely important since they define heritability, a key parameter ... estimates were similar (Tab VI) This may be explained bythe fact that the estimate of h in Ze was low, pointing to a relatively small effect of ‘‘perfect’’ individuals on inference when the Poisson...