... a a-helical coiled-coil domain, a DNA-binding domain, an SH2 domain, and a C-terminal transactivation domain. The deletion of exon 18 (52 bp) in the STAT 5A_ DE18 mRNA results ina translational ... a frameshift at Ala688, which led to premature termina-tion at the codon for amino acid 798 (Fig. 1A, STA-T 5A_ DE18). The C-terminal region ofthe variantlacked the transactivation domain and ... STAT5B mRNAs are alterna-tively spliced at the 3Â-end, resulting inthe production of b-isoforms truncated at the transactivation domain.STAT 5A b-isoforms and STAT5B b-isoforms aregenerated...
... Horse-radish peroxidase-conjugated antibody against caspase-3(#610325) was from BD Pharmigen, and antibody againstb-actin (A5 441) was from Sigma.Statistical analysisAll data are expressed as the ... OversaturatedDAGs, for example, were unable to interact withprotein kinase C, and this effect was attributed to the formation of gel-like domains (instead of liquid-crystalline domains) inthe ... synthesis inthe endoplasmic retic-ulum, apparently because ofthe formation ofa pool of oversaturated inter-mediates, represents the key initiating event inthe mechanism of saturatedfatty...
... usingIMAGEQUANTsoftware, anddepurination was calculated by relating the amounts of the small aniline-fragment and 5.8S rRNA and expressingvalues as a percentage.Reassociation and quantification ... Creation of ricin A chain variantsRicin A chain variants containing single amino acid sub-stitutions were generated by PCR mutagenesis and standard recombinant DNA techniques. Using the RTA ... images usingIMAGEQUANTsoft-ware. The depurination was calculated by relating the amounts of small aniline-fragment and 5.8S rRNA and expressing values as a percentage. Symbols indicate the experimental...
... Charles E. A Finch-Hatton, Henry Stormont A Goldsmith, Frank E.Gowans, James, Jr.Gray, Ernest A. W.Hallam, WilliamLarke, Frank ArthurMcLaren, AlexMorgan, C.Parr, JosephParr, SimonStuart, ... ãPart II. The Players, H–Z 877Appendix A. Tournament Information 1373Appendix B. Data Discrepancies 1385Appendix C. Players’ Name Variations 1388Bibliography 1391vii 20 Leitch, David A ... DavidLawson, Andrew A Leitch, David A Mason, GeorgeMcEwan, Douglas (II) 42McWatt, Thomas G.Mearns, Robert, Sr. 39Morris, Thomas Mitchell, Sr.Ness, David A Park, FrankPaxton, James Ferdinand DouglasPaxton,...
... changing. Therefore when making planning and coastal management, these unruly changes should be taken in account as a natural hazards to make reasonable measures for sustainable social-economic ... materials during flooding of delta plain area. Therefore this deposits are bad sorted (So>3) and always contains a lot of leaves and steams, sometime brackish molluscs also available. The ... Archive in Marine Geology and Mineral resources Centre. [14] C.D. Woodroffe, Late Quaternary evolution of coastal and lowland riverine plains of Southeast Asia and nouthern Australia: an overview....
... Sokur ofthe Institute ofIn uenza, Ministry of Health of the Russian Federation. The rst pair of primers(5Â-GGCCTTCAAGGCATTAAG-3Â,5Â-AAACAAATGGCCTGTCCG-3Â) spanned a 958 bp 5Â-part ofthe ZF5coding ... bases192210; the second siRNAZF5(5Â-GAGGAAGCAUGAGAAACUCUU-3Â and 5Â-GAGUUUCUCAUGCUUCCUCUU-3Â) matched bases 945963; and the third siRNAZF5(5Â-GGUCCUGAACUACAUGUACUU-3Â and 5Â-GUACAUGUAGUUCAGGACCUU-3Â) ... harvested afteradditional incubation for 5 h, and the recombinantprotein was purified by standard glutathione-agarose beadbinding procedures.Cell transfection, b-galactosidase and luciferaseassaysHepG2...
... cysteine-richpartTo test the reactivity ofthe mAbs against M1towards the human MUC5AC C-terminal cysteine-richFig. 1. The recombinant C-terminal cysteine-rich part of humanMUC5AC. A schematic ... picture ofthe recombinant C-terminal cyste-ine-rich part of human MUC5AC is given inthe upper part of the figure. The GDPH-cleavage site as well as the epitopes for the mAbs against myc (amyc) and ... superna-tants of hybridomas using immunohistology, as havingimmunoreactivity against the mucus of goblet cells of colon adenomas and a lack of reactivity against the mucus of goblet cells of normal...
... rst attempt to evaluate the mutual effects of pH(over the range ofthe alkaline Bohr effect) and NaClon the individual oxygen binding properties ofthe a and b subunits within liganded tetrameric ... afterphotodissociation, d, is calculated as the ratio of the quantum yield of BR, c, to that ofthe primary quan-tum yield of photodissociation, c0.Having the individual parameters of bimolecularoxygenation ... determined using a single flash photolysis experiment. The approach isbased on determination ofthe bimolecular associationrate constant of O2rebinding and the quantum yield of BR, c. The latter...
... to the zero-point energy per H atom in SiH4. We alsoestimate the temperature at 1 atom of partial pressure of H2from the standard partition function, within the harmonic approxima-tion, including ... absorption peaks start to appear inthe imag-inary part ofthe dielectric function for polarization along the wireaxis [9]. Vo et al. also clarified the effects of surface reconstructionon the opto-electronic ... [16] in which the ratio of surface energy to the distance from the centre of crystal to the surface is constant. Assuming that nanowire facetsduring the growth consist of clean surface, we have...
... disparities, and FGC, preparation of advocacy kits for parliamentarians and media leaders; and training of media as a key channel for disseminating messages regarding gender issues and elimination ... voluntary association inthe field of population and family planning inthe Arab World and Africa, and the pioneer and main provider of family planning activities in Egypt until the Ministry of ... Complementarity and Co-ordination UNFPA has always worked with a wide range of partners at the central level. These include: the Ministries of Health and Population, Information, Local Administration,...
... bilayer f rom the liquidcrystalline phase to a gel phase is accompanied by anincrease inthe thickness ofthe lipid bilayer and a decrease in the cross-sectional area, due to the ordering of ... of 100±220 M Pa causes a reversible phasetransition in parts ofthe lipid bilayer from the liquid crys-talline to the gel phase and the dissociation of and/or con-formational c hanges inthe ... Taniguchi, K., Katoh, T .,Yazawa, M., Hayashi, Y. & MaÊrdh, S. (1999) Acid-labile ATPand/or ADP/Pibinding to the tetraprotomeric formof Na/K-ATPase accompanying catalytic phosphorylation-dephosphory-lation...
... com-munication and exchange of information between the main importing Member States is improving: Member States meet regularly in an informal import group and information is exchanged via CIRCA and ... THE LAST ANNUAL REPORT AVAILABLE AT THE TIME OFTHE AUDITSubject Argentina Israel IndiaNew ZealandTunisia1Costa RicaMonitoring and supervisory activities carried out by the competent authority ... undertaking audit missions and gathering and exploiting the necessary data and information; (e) as regards imports, the Commission should ensure adequate supervision ofthe countries included in...
... the province in exchangefor the support of the Poles in the Austrianparliament. with a Polisharmy organized in America, of un-Amer-icanized Polishimmigrants,begananoffensiveagainst the Ukrainians,attackingthem from the rear. ... a temporaryoverthrowby the Germanmilitaryforcewasreestablished. In the latterpart of 1918, the Ukrainians of EasternGa-licia(also predominantlyUkrainianandanciently, Accordingto the InternationalEncyclopedia, the entire Austrianprovince of Galicia(westernandeast-ern) ... Ukrainians.Accordingto the EncyclopediaBrittanica, the formerpredominate in the West and in the bigtowns,and the latter in the East.Accordingtoofficial statistics of the Austrianpro-vincialgovernment of Galicia, preparedandpublishedbyleaders of Polishpolitical...
... in rural areas.4. Overall ranking of factors influencing decision to workor stay in rural areasKey informants at national level felt that inequality of pay was the main factor behind the problem ... region, allowances are used more seriously to retainstaff in rural areas, ranging from 2-5 times basic salary.Overall, in Vietnam, according to the national healthaccounts, one third of financing ... language journals) on the factors affecting the willingness of medical doctors to accept and remain in posts in rural areas of Vietnam.This study forms part ofa labour market survey whichwas...