everybody gets into the act
Tài liệu Báo cáo khoa học: Solution structure of hirsutellin A – new insights into the active site and interacting interfaces of ribotoxins docx
... the activity Given the 3D structure of the HtA active site, and the interactions between side chains, we propose that D40, H42, R95 and F126 also form part of it As in other ribotoxins, the active ... the classical ribotoxins, but catalyzes the same hydrolytic reaction with similar efficiency Hence description of the new interactions established in the active site is also of relevance The active ... lead to new electrostatic interactions at the active site of this ribotoxin They are important for protein activity as electrostatic interactions define the characteristic microenvironment in...
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Báo cáo khóa học: Insight into the activation mechanism of Bordetella pertussis adenylate cyclase by calmodulin using fluorescence spectroscopy pptx
... ÔclosedÕ active structure in its presence In the inactive structure, the active site would not be completely shaped An observation supporting this model was the large increase in the affinity of the ... in this respect Beside the fact that they explained the increase in Ant-dATP fluorescence intensity by a factor of on binding to AC–CaM [22], they allowed the signals of the free and bound probe ... suggests, however, that the activation by CaM is the result of a large conformational change involving a major portion of the protein [23] In the absence of 3D data describing the interaction of CaM with...
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Báo cáo khoa học: Insights into the activation of brain serine racemase by the multi-PDZ domain glutamate receptor interacting protein, divalent cations and ATP ppt
... both the Km and the Vmax of the reaction The Km for d-serine synthesis increased from 1.9 mm in the absence of GRIP fragment (filled circles) to 3.4 in its presence (empty circles), whereas the ... available on the Internet (see Experimental procedures) The results provided by the program were fully consistent in that all of them rendered the same hit with the highest score: the SR from the fission ... For example, neither the PDZ4, nor the PDZ5 domain of GRIP bind to the GluR2 subunit of the AMPA channel independently, with the concerted action of both being necessary for the association [15]...
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An investigation into the use of communicative activities in teaching english speaking to 10th graders at upper secondary schools in nghe an luận văn thạc sĩ giáo dục học
... Activities Social interaction activities add a further aspect to the functional activities, the activity therefore become a ‘social interaction activity’ In these activities, the learners’ choice ... with the activities whereas 4.2% were bored with these activities Nevertheless 29% of students show their interest in speaking activities and 4.2% confirmed that they were confident with these activities ... and practiced, and their language knowledge to produce their speaking communicatively What they produce reflects the result of their practice stage, their interests or views At this stage, the...
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Tài liệu Báo cáo khoa học: Structural insights into the substrate specificity and activity of ervatamins, the papain-like cysteine proteases from a tropical plant, Ervatamia coronaria ppt
... to the solvent (Fig 2B) On the other hand, the P3 moiety of E-64 in each of the of the two ervatamin-C molecules in the asymmetric unit mainly interacts with His61 in both molecules (Fig 2B) The ... proton from the catalytic Cys present at the N-terminus of the helix to the His of the dyad [19,50,51] The first stage of catalysis is mediated by the highly active thiolate ion of the Cys Biochemical ... in the activity of the enzyme In the case of ervatamin-A, polarizibility and active site plasticity can therefore be considered to be the primary factors responsible for its observed high activity...
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Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot
... that the former is likely to be in the Cterminal half and the latter in the N-terminal half of the protein [29,48±51] Sequence-based structure prediction methods suggest that the caseins are of the ... corresponds to the 412-amino-acid isoform of human brain tau At neutral pH, the tau samples showed aggregation in the laser beam, with the aggregates falling to the bottom of the cell, so that the concentration ... strand (rather than b sheet from the appearance of the amide I ROA, see below) [18] The negative intensity in a similar region of the ROA spectrum of b-casein may have a similar origin The two...
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Báo cáo khoa học: New insights into the functions and N-glycan structures of factor X activator from Russell’s viper venom pot
... venom factor X activator H.-S Chen et al A B the corresponding D ion Third, the 0,4A ion would include the 6-arm substituents, but not the extra GlcNAc residue, if the latter bisects the b-Man ... First, the D ion formed at the bisected 3,4,6-linked b-Man residue carried the extra bisecting GlcNAc residue together with the 6-arm substituents Second, a characteristic loss of both the bisecting ... The column was eluted at a flow rate of 1.0 mLÆmin)1, and fractions of 0.5 mL were collected After assay for coagulation activity, the active fractions were pooled, dialysed, and lyophilized The...
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Integrating Gender into the World Bank’s Work: A Strategy for Action potx
... required by the commitment of the Bank and its member countries to the goals set forth in the United Nations Millennium Declaration, the Beijing Platform for Action, and the Convention on the Elimination ... countries The Beijing Platform has even broader goals: The goals of the Millennium Declaration are intended to further progress on the some of the 12 critical areas for action identified by the Beijing ... development The main conclusions and recommendations of the CGA are then used as the basis for discussions with the government and other stakeholders about any desirable gender-related actions These...
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Báo cáo y học: "Qualitative and quantitative research into the development and feasibility of a video-tailored physical activity intervention" pptx
... double for those under 40 years of age The reason for the low support might result from the fact that the average age of participants in both the focus groups and the survey was relatively high (47.4 ... participants with the option to choose one of four virtual characters to guide them through the intervention, consistent with the focus group outcomes of the present study, preferences for the virtual ... and was designed to reflect the characteristics of the population by the most recent Australian Census All respondents were 18 years of age or older at the time of the survey, and were living...
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homomorphisms of the fundamental group of a surface into psu(1,1), and the action of the mapping class group
... can use the action of the group G to change also h to an elliptic element and therefore use the [PX02] method The result on the action of ΓΣ on Hom π1 (Σ), G is going to be very similar to the main ... is the Teichm¨ller space of Σ An open question is to investigate whether there is a u nice geometric description for some part of the other components What can one say about the action of the ... granted by the head of the major department or the Dean of the Graduate College when in his or her judgment the proposed use of the material is in the interests of scholarship In all other instances,...
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An investigation into the perceptions and actual behaviors of the teachers and the students at the faculty of Foreign Language of Ho Chi Minh City University of.PDF
... and then putting the students into appropriate groups, telling them the aims of the activity or giving them some time to get ready for the task In the mean time, the students think that the most ... the mistakes that they make during the discussion 8 However, the teachers not think so They not pay much attention to the errors but to the proficiency and the ideas rather than correcting the ... Background to the study 2.1.1 The students at FFL - HUI - A lot of them are from the south of Vietnam, others are from the central, even from provinces in the north of the nation - There are about...
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An investigation into the perceptions and actual behaviors of the teachers and the students at the faculty of Foreign Language of Ho Chi Minh City University of20150227.PDF
... what to The teachers’ and the students’ behaviors during activity What the teachers and the learners during the group work is the most important in the procedure of organizing an activity In the ... for the teachers to keep their eyes to all the groups at the same time The quality of an activity, therefore, depends so much on the students‟ volunteer to study as well as their consciousness The ... activity, the investigated teachers think that they should give clear instructions and then putting the students into appropriate groups, telling them the aims of the activity or giving them some...
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AN INVESTIGATION INTO THE USE OF PAIR WORK AND GROUP WORK ACTIVITIES TO DEVELOP SPEAKING SKILLS OF THE FIRST YEAR ENGLISH MAJOR STUDENTS AT THE FACULTY OF FOREIGN LANGUAGES, THAI NGUYEN UNIVERSITY = Nghiên cứu thực trạng sử dụng các hoạt động theo cặp và
... the real life, they actively 13 join in the activities because of the feeling that they are doing with their language, taking the risks of experimenting what they have learned Additionally, the ... opportunities to practise them separately The learners; therefore, are being trained in the part-skills of communication rather than practicing the total skill to be acquired They are subdivided into structural ... divides the class into mixed ability groups, the best students in the group will have to the task while the weakest ones switch off and become disruptive Teacher therefore should put the students into...
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Changing a sentence into the passive when the active verb is in the simple past or past continuous tense
... 4 Mother was making a cake The girl was painting a picture Answers A poem was being written by Megha Clothes were being washed by the woman The house was being built by the masons A ... the woman The house was being built by the masons A cake was being made by mother A picture was being painted by the girl Be first to know when grammar rules change! Sign up to our newsletter...
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Investigations into the chemopreventive potential of stilbenes, indolinones and isoindigos synthesis and mode of action studies
... with a strong base The 18 reaction of the ylid with the carbonyl group of the benzaldehyde yielded the stilbene, as shown in Scheme 2-1 Scheme 2-1: The mechanism of Wittig reaction X Ph3P X HC ... product The synthesis of the 3-substituted indolin-2-ones (1-48) was carried out in the presence of the base piperidine as catalyst Under these conditions, the enol tautomer of oxindole forms the ... oxidants The Keap1-Nrf2 complex is disrupted under these conditions and the liberated Nrf2 migrates to the nucleus where it binds (in heterodimeric forms with other transcription factors) to the ARE...
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An investigation into the attitudes of teachers and students at the hanoi college of industrial economics towards speaki
... get the most proficiency, the teacher can divide the class into pair or groups In each pair or each group, one acts as the asker, the other the answerer, let them discuss for a few minutes and they ... about the teachers’ attitudes towards the speaking skill lessons, the 37 researcher asked the teachers about their opinions about the contents of the topics, the activities and the time of the ... unless they regard the materials they are taught as worth learning Therefore, the task of the teachers is to find out their students‟ goal and the topics 48 they want to learn and build these in the...
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