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evaluation of genotoxicity studies

Báo cáo y học:

Báo cáo y học: ":Evaluation of the Patient Acceptable Symptom State in a pooled analysis of two multicentre, randomised, double-blind, placebo-controlled studies evaluating lumiracoxib and celecoxib in patients with osteoarthritis" pptx

Báo cáo khoa học

... parallel-group, 13-week studies of patients with OA of the knee and of identical design was conducted Methodology for the studies has previously been described elsewhere in detail [6,7] and both studies were ... provides an evaluation not only of the concept of 'feeling good' but also of 'feeling good as soon as possible.' Time taken to achieve sustained satisfaction combines the concept of 'feeling ... assessment of disease activity, and the WOMAC™ questionnaire total score) [6,7] Here, we report on a pooled analysis of the above two studies This analysis evaluated the effectiveness of lumiracoxib...
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Báo cáo y học:

Báo cáo y học: " Evaluation of next generation sequencing platforms for population targeted sequencing studies" pot

Báo cáo khoa học

... amount of sequence but, for the platforms that produce short-sequence reads, greater than half of this sequence is not usable On average, 55% of the Illumina GA reads pass quality filters, of which ... region of chromosome 11 amplified by three long-range PCR products (red rectangles) (b) A heat-map colored matrix displays the coefficient of correlation of coverage across the entire 260 kb of analyzed ... indicative of the real performance of NGS platforms for de novo detection of variants in human sequences Interestingly, our analysis indicates that ABI Sanger has a false negative rate of approximately...
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Novel methods for quantitative analysis and evaluation of effects of chronic exposure to microcystins by capillary electrophoresis and metabolomic studies

Novel methods for quantitative analysis and evaluation of effects of chronic exposure to microcystins by capillary electrophoresis and metabolomic studies

Cao đẳng - Đại học

... Figure 8: Illustration of EOF inside a fused silica capillary 22 Figure 9: Illustration of the order of migration of ions in CE 22 Figure 10 Illustration of EOF profile 23 Figure ... (PUB) of Singapore’s national water agency, for their assistance in the collection of the water samples, Professor Hanry Yu and Ms Teo Siow Thing of Department of Physiology NUS for provision of ... INVESTIGATION OF MICROCYSTIN TOXICITY 84 4.0 Development of Metabolomics Approaches for the Investigation of the Effect of Exposure of a Human Cell Line to Non Cytotoxic Amounts of Microcystins...
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Chemical studies of panax notoginseng and related species and evaluation of potential antiplatelet and anticoagulant effects

Chemical studies of panax notoginseng and related species and evaluation of potential antiplatelet and anticoagulant effects

Tổng hợp

... presentations iii Table of contents v Summary ix List of tables xi List of figures xiii List of abbreviations xvi Chapter 1.1 1.2 1.3 1.4 Introduction Herbal medicines 1.1.1 Importance of herbal medicines ... 6.5 Effects of extracts of various Panax species on PT and APTT of human blood plasma in vitro (n≥3) 173 Table 6.6 Effects of fractions from steamed P notoginseng on PT and APTT of human blood ... medicines are often taken complementarily with therapeutic drugs, drug-herb interactions have been a major safety concern, especially when healthcare professionals are often unaware of the type of herbal...
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Part 1 total synthesis and biological evaluation of antillatoxin and fragments part II synthetic studies towards the total synthesis of cytochalasans and tuberostemonine

Part 1 total synthesis and biological evaluation of antillatoxin and fragments part II synthetic studies towards the total synthesis of cytochalasans and tuberostemonine

Cao đẳng - Đại học

... (B.Sc (Hons), University of Malaya) (M.Sc National University of Malaysia) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARMENT OF CHEMISTRY NATIONAL UNIVERSITY OF SINGAPORE 2005 ACKNOWLEDGEMENTS ... stereochemistries of C4 and C5 In our group, we have been working on the synthesis of the isomers of C4 and C5 as NOE studies of large rings is known to be unreliable.9 Later, the NMR data of the synthetic ... cultures of rat cerebellar granule cells In the latter study, morphological evidences of antillatoxininduced neurotoxicities included swelling of neuronal somata, thinning of neurites, and blebbing of...
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Polish Journal of Environmental Studies

Polish Journal of Environmental Studies

Môi trường

... properties of semipermeable membranes, physiological condition of the organism, physical characteristics of the environment, kind and amount of food, level of its contamination, kind of organisms ... and type of pollutants Effective accumulators of pollutants are mollusks, often applied as bioindicators of water pollution with heavy metals [55,56] The properties of some populations of these ... most often in analyses of atmospheric depositions, soil quality and wa- ter purity Responses of trees and shrubs to the presence of pollutants are also observed The assimilatory organs of trees,...
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Báo cáo y học:

Báo cáo y học: "Medical resource utilization among patients with ventilator-associated pneumonia: pooled analysis of randomized studies of doripenem versus comparators"

Y học thưởng thức

... other studies [4-6] because of activity against key pathogens Consideration of the influence of appropriateness of empiric therapy against subsequently identified pathogens was beyond the scope of ... Discussion The results of this pooled analysis of two phase III studies indicated that initial use of doripenem in patients with VAP was associated with shorter durations of mechanical ventilation ... cost of hospitalization as demonstrated in a recent economic analysis of studies and [29] Using discrete event simulation, Kongnakorn and colleagues [29] estimated that use of doripenem instead of...
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Báo cáo y học:

Báo cáo y học: "Evaluation of the Prevalence of Concomitant Idiopathic Cyclic Edema and Cellulit"

Y học thưởng thức

... observation of cyclic edema demonstrated the success of the treatment and the need for its control, but we had no idea of the high prevalence of edema in the more advanced grades of cellulite The lack of ... were excluded An evaluation for idiopathic cyclic edema is routinely made in the diagnosis of cellulite, in obesity and in other evident causes of clinical edema The diagnosis of idiopathic cyclic ... and with the combination of drugs control of edema was attained Discussion This study illustrates the association of idiopathic cyclic edema with more advanced cases of cellulite There are no...
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Báo cáo y học:

Báo cáo y học: " Evaluation of Lumbar Facet Joint Nerve Blocks in Managing Chronic Low Back Pain: A Randomized, Double-Blind, Controlled Trial with a 2-Year Follow-U"

Y học thưởng thức

... the prevalence of low back pain of 162% with an annual increase of 11.6% The widely held belief that most of the episodes of low back pain will be short-lived, with 80% to 90% of these attacks ... lumbar radiofrequency neurotomy.29-31 The exact mechanism of the therapeutic effect of lumbar facet joint nerve blocks is not known, whereas radiofrequency neurotomy causes denaturing of the nerves ... Classification of Chronic Pain; Descriptions of Chronic Pain Syndromes and Definition of Pain Terms, 2nd ed; Task Force on Taxonomy of the International Association for the Study of Pain Seattle:...
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Báo cáo y học:

Báo cáo y học: "Evaluation of maternal infusion therapy during pregnancy for fetal development"

Y học thưởng thức

... in 88.4% of cases and in 93.8% of controls The informed consent document was signed by 98.4% of case mothers Personal identifiers (i.e name and address) were deleted from the record of cases ... keep them The personal data of controls are not recorded in the HCCSCA The fourth step was the evaluation of maternal infusion in five different aspects 1) The source of information All infusion ... of infusion according to the month of gestation in the case and controls groups is shown in Table There were two peaks of infusion treatments The first peak was connected with the treatment of...
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Báo cáo y học:

Báo cáo y học: "Evaluation of Fractional Analysis of Bronchoalveolar Lavage Combined with Cellular Morphological Features"

Y khoa - Dược

... activity of disease in sarcoidosis or HP In addition, finding of encapsulated exudates may suggest desquamation of early stage of Masson body which implies possible diagnosis in a limited number of ... Patients’ group showing the highest rate of lymphocytes Of the 2260 patients, 488 (21.6%) showed a lymphocyte rate of higher than 40% Clinical diagnoses of these patients included sarcoidosis (22.1%), ... infiltration of mast cells implies histological feature of organization of collagenous matrices or interstitial fibrosis 10 Basophilic leukocytes were never found in the normal control and most of the...
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An evaluation of the material “basic english iii” for the second year non- english major students at bac giang teachers’ training college

An evaluation of the material “basic english iii” for the second year non- english major students at bac giang teachers’ training college

Thạc sĩ - Cao học

... in materials evaluation including definitions of materials evaluation, purposes for materials evaluation, types of materials evaluation, materials evaluators, models for materials evaluation, ... purposes of the course as well as the available facilities and constraints of a particular situation 1.2 Materials Evaluation 1.2.1 Definitions of Materials Evaluation There are many ways of defining ... research 1.2.3 Types of Materials Evaluation In materials evaluation literature different authors offer different ways of categorizing it Robinson (1991:59) classifies materials evaluation into three...
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Construction engineering students' evaluation of the esp programme at vinh university

Construction engineering students' evaluation of the esp programme at vinh university

Thạc sĩ - Cao học

... evaluation, etc Teacher evaluation task evaluation, etc Learners evaluation evaluation of sequencing practice, ect evaluation of levels of participation etc Figure 3: Macro- and micro -evaluation in language ... purpose of the evaluation 1.2.2 Types of programme evaluation According to Stufflebeam (1971), there are four types of programme evaluation which are identified as: context evaluation, input evaluation, ... ESP (definition of ESP, classification of ESP and the development of ESP), evaluation (terminology definition, types of programme evaluation, purposes for evaluation, criteria for evaluation and...
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Evaluation of consolidation parame ters in CL tests

Evaluation of consolidation parame ters in CL tests

Khoa học tự nhiên

... the discretization steps of Ds became different in the course of the test For the next steps of Dsn calculated as above, excess of the pore water pressure Evaluation of consolidation parameters ... used formulae and the Fig Comparison of different methods of cv estimation in the context of theoretical analysis of the CL consolidation process Evaluation of consolidation parameters in CL tests; ... the changes of Hi length of the drainage path This point Fig Comparison of cv characteristics estimated by various methods A — estimation of cv value by different formula; B — changes of cv v l...
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Evaluation of institutional method used in teaching of english in secondary schools of Haripur District

Evaluation of institutional method used in teaching of english in secondary schools of Haripur District

Khoa học xã hội

... INSTITUTE OF EDUCATION AND RESEARCH UNIVERSITY OF PESHAWAR (2005) EVALUATION OF INSTRUCTIONAL METHODS USED IN TEACHING OF ENGLISH IN SECONDARY SCHOOLS OF HARIPUR DISTRICT Submitted ... sphere of this mortal life APPROVAL SHEET The thesis entitled Evaluation of instructional method used in teaching of English In secondary schools of Haripur District Accepted by the faculty of ... 1-3 I 1.1 Background of the Study 1.2 Statement of the Problem 1.3 Objectives of the Study 1.4 Significance of the Study 1.5 Hypothesis 1.6 Delimitation of the Study II REVIEW OF RELATED LITERATURE...
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IMPROVING INFORMATION SYSTEM SUPPORTING MONITORING AND EVALUATION OF GREATER MEKONG SUBREGION SUSTAINABLE TOURISM DEVELOPMENT PROJECT  IN VIET NAM

IMPROVING INFORMATION SYSTEM SUPPORTING MONITORING AND EVALUATION OF GREATER MEKONG SUBREGION SUSTAINABLE TOURISM DEVELOPMENT PROJECT IN VIET NAM

Quản trị kinh doanh

... works Evaluation is implemented in phases of investment process: Inception evaluation; Midterm evaluation; Completion evaluation; Impact evaluation or after project evaluation Monitoring and Evaluation ... implementation Evaluation - Internal evaluation - External evaluation - Implementation - Results - Impacts - Inception evaluation - Midterm evaluation - Completion evaluation - Impact evaluation ... Ministry of Culture, Sports and Tourism IS Information System IT Information Technology M&E Monitoring & Evaluation MPI Ministry of Planning and Investment MOF Ministry of Finance MBA Master of Business...
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Stability and in vivo evaluation of pullulan acetate as a drug nanocarrier

Stability and in vivo evaluation of pullulan acetate as a drug nanocarrier

Tài liệu khác

... 1.  FT-IR spectra of PA (a) and pullulan (b) 500 Stability and in vivo evaluation of pullulan acetate   555 (2008) also reported that the smaller size of NPs may be in favor of longer circulation ... integration value of acetyl protons at 1.8–2.2 ppm and B is that of OH protons and H-1 to H-6 protons of pullulan moiety observed at more than 3.5 ppm Preparation and characterization of PANs and PA/EPI ... informahealthcare.com by University of Technology Sydney on 03/01/11 For personal use only Stability and in vivo evaluation of pullulan acetate   553 aqueous media The hydrophobic core of these selfassembled...
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