emergency radiation therapy in pediatric oncology
Infliximab therapy in pediatric Crohn’s disease: a review docx
... and in inducing and maintaining remission in patients with active CD ACCENT I was a multicenter randomized double-blind international trial studying retreatment and remission maintenance in adult ... favorable maintenance of clinical remission Since CD may progress from intestinal inflammation to strictures and penetrating disease, including fistulas and abscess formation, mucosal healing has ... weeks for maintenance of remission After 54 weeks, the initial clinical response was maintained in only 17% of patients in the single dose group compared to 43% of patients maintained on 5 mg/kg...
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Báo cáo khoa học: "Intraoperative radiation therapy in the treatment of early-stage breast cancer utilizing xoft axxent electronic brachytherapy" ppt
... 366:287-2106 Vicini F, Kestin L, Chen P, Benitez P, Goldstein NS, Martinez A: Limited-field radiation therapy in the management of early stage breast cancer J Natl Cancer Inst 2003, 95:1205-1210 King TA, ... seen in consultation by her surgeon and radiation oncologist Radiation treatment options were explained to the patient, including the standard of care, 6– weeks of whole breast radiation therapy, ... radiation oncologist remained in the room during the radiation delivery either wearing lead aprons or standing behind a mobile radiation shield At the completion of the radiation, the balloon and...
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Báo cáo khoa học: "Whole abdomen radiation therapy in ovarian cancers: a comparison between fixed beam and volumetric arc based intensity modulation" ppt
... carcinoma in complete surgical remission after induction chemotherapy: a randomized, controlled, clinical trial comparing whole abdominal radiotherapy, chemotherapy, and no further treatment Int ... complications in patients treated with abdomino-pelvic radiation therapy for ovarian carcinoma Int J Radiat Oncol Biol Phys 1992, 22:847-51 Lindner H, Willich H, Atzinger A: Primary adjuvant whole abdominal ... body volume included in the CT scan minus the PTVs), the integral dose, “DoseInt” was defined as the integral of the absorbed dose extended to over all voxels excluding those within the target...
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Báo cáo khoa học: "Adjuvant radiation therapy in metastatic lymph nodes from melanoma" doc
... analyzed using the grading scale introduced by Ballo et al in 2006 [9] The classification consisted in grade toxicity for an asymptomatic finding noted at the time of the follow-up physical examination; ... without radiation therapy, and without systemic therapy Having four or more involved lymph nodes, extracapsular extension and node size greater than centimetres were our main indications for radiation ... symptomatic finding requiring any form of medical therapy (e.g., compressive sleeve for lymphedema, physical therapy for neuropathy, or long-term use of pain medication); and grade for toxicity requiring...
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Báo cáo khoa học: " Radiation therapy in primary orbital lymphoma: a single institution retrospective analysis" docx
... cavity According to literature [6,8-25], it is possible to obtain local control in the range of 89-100% using radiotherapy in low or moderate doses as 25-36 Gy A summary of findings of some of ... reported in any patient Keratitis occurred in patients (10.6%), xerophthalmia in (19.1%), cataract in 12 (25.5%), corneal ulceration occurred in one patient (2.1%), and minor retinopathy in one ... failure of 44 months: two patients relapsed in the other eye, at ipsilateral laterocervical nodes, in the abdomen, in the mediastinum, in the trunk skin, and in a vertebral bone All relapsed patients...
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Báo cáo khoa học: " Whole brain radiation therapy in management of brain metastasis: results and prognostic factors" ppsx
... palliation of brain metastases Final results of the first two studies by the Radiation Therapy Oncology group Int J Radiat Oncol Biol Phys 1980, 6:1-9 Vermeulen SS: Whole brain radiotherapy in the treatment ... partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials Int J Radiat Oncol Biol Phys 1997, 37:745-754 Patchell RA, Regine WF: ... demonstrated in table Discussion Brain metastases are the most common form intra cranial tumor accounting significantly more than one- half of brain tumors in adults Because of advanced in the diagnoses...
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Báo cáo khoa học: " A phase III trial comparing an anionic phospholipid-based cream and aloe vera-based gel in the prevention of radiation dermatitis in pediatric patients" pdf
... of radiation may be informative Cytokine and cellular responses to radiation therapy in the skin have been investigated to identify targets to mitigate the consequences of ionizing radiation therapy ... comparing Best Supportive Care to Biafine as a prophylactic agent for radiation- induced skin toxicity for women undergoing breast irradiation: Radiation Therapy Oncology Group (RTOG) 97-13 Int ... assessing the effectiveness of Biafine cream as a prophylactic agent for radiation- induced acute skin toxicity to the breast in women undergoing radiotherapy with concomitant CMF chemotherapy Int...
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Báo cáo khoa học: " The prognostic value of nestin expression in newly diagnosed glioblastoma: Report from the Radiation Therapy Oncology Group" potx
... distinguish positive tumor areas within individual cores of the TMA slide Both staining intensity and its relative area within a specimen were quantified Staining intensity was acquired in a ... Radiation Oncology 2008, 3:32 Background Nestin is an intermediate filament protein that was initially identified during studies involving cellular organization of the developing rat ... evaluating nestin expression in GBM may be more informative when studied in the context of markers more specific to tumor stem cells, including CD133 [5] In addition, future investigations evaluating...
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Modern Practices in Radiation Therapy Edited by Gopishankar Natanasabapathi pdf
... delivering stereotactic body radiotherapy is crucial Image-guided respiratory-gated radiation therapy has been a major advancement in minimizing inter- and intra- fractional target variations To minimize ... 1997; Spitz et al 1997; Klinkenbijl et al 1999) In an effort to increase the number of patients receiving adjuvant therapy, chemotherapy and radiation therapy can be administered pre-operatively ... US Intergroup study compared gemcitabine vs infusional 5-FU chemotherapy for one month prior to and three months after chemoradiation, consisting of continuous infusional 5-FU, as adjuvant therapy...
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Frontiers of Radiation Therapy and Oncology Vol. 34 doc
... treatments, including radiotherapy One could interfere with EGFR binding or with individual steps in downstream processes For that purpose, a number of protein kinase inhibitors are currently under investigation ... transcription allowing cell progression into S phase The action of cyclin D/cdk4 on Rb phosphorylation can be inhibited by a number of genes including p27, p21, and INK (inhibiting kinases) that include ... to radiation- induced apoptosis Radiation and EGFR Signaling There is growing evidence that ionizing radiation can mimic the action of ligand-receptor binding, which triggers downstream signaling...
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Báo cáo khoa học: "Supracricoid partial laryngectomy with cricohyoidoepiglottopexy in patients with radiation therapy failure" ppsx
... Surgical margins were intra-operatively assessed in all cases and, when these were close to being positive, in some cases the margin was widened to include one arytenoid Definitive surgical margins were ... months, postradiotherapy) In case #8, concomitant chemoradiotherapy was used However, radiotherapy doses were only able to be accurately established in four cases because the remaining cases were ... gastrostomy; NFT = nasogastric feeding tube; AMI = acute myocardial infection; GI = gastrointestinal; CWI = cervical wound infection, RP = Rupture of the pexy control was obtained in 7/8 patients (87%) (Table...
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Báo cáo khoa học: "SemiIntensity-modulated radiation therapy (IMRT) vs. 3D conformal radiotherapy (3DCRT) in locally advanced rectal cancer (LARC): dosimetric comparison and clinical implications" pptx
... tridimensional conformal radiotherapy (blue line) f3DCRT: modificated tridimensional conformal radiotherapy (pink line) IMRT: intensity modulated radiation therapy (green line) Table Irradiated Body ... planning target volume c3DCRT: conventional tridimensional conformal radiotherapy (blue line) f3DCRT: modificated tridimensional conformal radiotherapy (pink line) IMRT: intensity modulated radiation ... homogeneity index; CI: Conformity index c3DCRT: classic tridimensional conformal radiotherapy; f3DCRT: fitting tridimensional conformal radiotherapy, IMRT: intensity modulated radiation therapy; ...
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Báo cáo khoa học: "Use of kilovoltage X-ray volume imaging in patient dose calculation for head-and-neck and partial brain radiation therapy" pptx
... head-and-neck patients, including nodal mass shrinkage and patient weight loss during the course of radiation therapy, can occur [28,29] For these cases, repeat CT imaging and re-planning may be essential ... sets Finally, the initial dose distribution matrix calculated on the planning CT was imported in the treatment planning system and displayed on the kV-CBCT dataset using scripts developed in- house ... different image modalities is widely used in radiotherapy for delineating the region of interests[27] As the registration algorithms in the commercial treatment planning systems generally use rigid body...
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Báo cáo khoa học: "Plan comparison of volumetric-modulated arc therapy (RapidArc) and conventional intensitymodulated radiation therapy (IMRT) in anal canal cancer" doc
... randomized intergroup study J Clin Oncol 1996, 14:2527-2539 Intensity modulated radiation therapy collaborative working group: Intensity modulated radiotherapy: current status and issues of interest Int ... L, et al: Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: ... patients including iliac crests sparing measurements Methods Patient selection, simulation and treatment planning Ten patients with localized anal canal carcinoma treated with IMRT in our institution...
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Báo cáo khoa học: "An ultrasonographic evaluation of skin thickness in breast cancer patients after postmastectomy radiation therapy" docx
... without pain, or skin fibrosis due to radiation exposure In an effort to explain the increased breast reconstruction complications in patients due to increased radiation dose to the skin, a separate ... skin thickness Skin reactions occurring within a time interval of up to three months following irradiation are defined as early reactions and reactions presenting after three months following ... resection and radiation therapy [34] The authors also observed an increase in skin thickness followed by a decrease in four of nine patients for whom serial ultrasound scans were performed beginning one...
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Báo cáo khoa học: "Postmastectomy irradiation in breast in breast cancer patients with T1-2 and 1-3 positive axillary lymph nodes: Is there a role for radiation therapy" ppsx
... Society of Clinical Oncology Postmastectomy radiotherapy: clinical practice guidelines of the American Society of Clinical Oncology J Clin Oncol 2001, 19:1539-1569 10 Recht A, Bartelink H, Fourquet ... LRR Clinical characteristics of patients with LRR are shown in Table LRRs’ histologic types were invasive ductal carcinoma for patients and invasive lobular carcinoma Cosar et al Radiation Oncology ... give us better information the role of PMRT in this patient group [6] Radiation oncologists often confront patients with 1-3 positive lymph nodes following MRM in their routine clinical practice...
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Báo cáo khoa học: "Intensity modulated radiation therapy (IMRT): differences in target volumes and improvement in clinically relevant doses to small bowel in rectal carcinoma" pps
... 3DCRT [8,16,17] In our study, in addition to these findings, we found IMRT capable of reducing small bowel volumes receiving potentially toxicity-inducing intermediate- and low-dose irradiation, at ... Chemoradiotherapy Utilizing Intensity Moldulated Radiation Therapy (IMRT) in Combination with Capecitabine and Oxaliplatin for Patients with Locally Advanced Rectal Cancer [http://www.rtog.org/ClinicalTrials/ProtocolTable/StudyDetails.aspx? ... gastrointestinal toxicity in these patients treated with IMRT Furthermore, reduction in the small bowel V45Gy using IMRT may lead to lower rates of late gastrointestinal toxicity [20] Again, in the...
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Báo cáo khoa học: "Dose distribution in the thyroid gland following radiation therapy of breast cancer-a retrospective study" ppsx
... thyroid gland sizes ranging from 3.6-6 cm in length, 1.5-2 cm in width and 1-2 cm depth are reported [23], which are more in agreement with our study Finally, as our findings are principally based on ... body irradiation A median thyroid dose in Bonato et al.’s study was 42 Gy (inter-quartile range: [27-72Gy]) [15] After high-dose radiotherapy the years incidence of Johansen et al Radiation Oncology ... The clinical target volume, both lungs and the heart, but not the thyroid gland were routinely delineated in the planning CT images Treatment planning and dose calculation were performed using...
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