... indentation ofthe pharyngeal roof and, hence, originates from the ectoderm Regarding thedevelopmentofthe remaining cranial area, it may be mentioned that thedevelopmentofthe primary nasal ducts ... Medicine 2008, 4:13 mesenchymal cells moves between the pharygeal roof and the bottom ofthe brain [2] These mesenchymal cells later differentiate into the primordia ofthe cranial base The cells ... between the pinching off hypophysis and the pharyngeal roof has been reported, clear evidence of development- related cell processes during pharyngeal roof fusion is lacking Figure not inthe Rathke...
... either increasing/decreasing the replication of cells ofthe osteoblastic lineage or modifying the differentiated function oftheosteoblast It would, therefore, be beneficial to stimulate the osteoblastic ... murine calvaria In vivo effects overgrowth of bone, leading to osteosclerosis Since new boneformation is primarily a function ofthe osteoblast, agents regulating boneformation can act by either ... increase inosteoblast accumulation and new boneformationin cultures of neonatal murine calvaria (Fig 1) Transient exposure ofbone cultures to statins was enough to initiate a cascade ofbone formation, ...
... drops, the search range shrinks and the focus ofthe search shifts to improving the quality ofthe current solution, in other words, the increasing partition of “better” points is favored The numerical ... spectroscopy and the number of components in a mixture was predicted even in case where the spectra ofthe individual compounds were very similar (Rasmussen, 1978) Inthe 1980s, the information entropy ... encounters many difficulties inherented from the trilinear form, including ambiguity ofthe correct model size (number of factors involves inthe system), model mismatch and the interference by noise...
... In Raw Water On The Ozonation Of Geosmin And 2-MIB OZONE SCIENCE & ENGINEERING 15, 1-18 Morioka, T (2001) The Study on the Application of Ozonation forthe Removal ofthe Taste and Odor-Causing ... classed as practical Technique for suppressing bromate formationThe ozonation of raw water containing bromide ions leads formationofthe by-product bromate as shown in Fig ( Hagg et al., 1983; ... result in an increase in ozone concentration To increase ozone concentration, therefore, it is advised to use oxygen instead of air High concentration ozonizer The original principles of ozone...
... linear regression line ofthe Ct values forthe DNA standards versus logarithm of their starting copy number was constructed A typical linear regression line is shown in Figure The averages of ... RESULTS AND DISCUSSION Developmentof Quantitative PCR method Specificity ofthe primer set was evaluated based on the melting curve and the sequencing analysis Melting peaks ofthe PCR product from ... Biosystem) and the T3 Thermocycler (Biometra) Samples were preincubated at 95 °C for 10 The PCR cycle consisted of 30 sec of denaturation at 94 °C, 30 sec of annealing at 50 °C, and of extension...
... 'all the present of earth vanished into the future of Heaven, and the Kingdom ofthe Infinite arose upon the ruins ofthe finite.' The beauty of earth was looked upon as an enchantment ofthe ... Octavius of Minucius Felix, a writing full of genuine human feeling ofthe time of Commodus, the mixture ofthe heathen culture and opinions of antiquity with the Christian way of thinking has ... man in isolated cases, as, for instance, in Samuel i.: 'Ye mountains of Gilboa, let there be no dew, neither let there be rain upon you, nor fields of offerings: for there the shield ofthe mighty...
... of Chapter Interviewees’ assessment of cross-margining agreements Interviewees’ assessment of clearing links Interviewees’ assessment ofthe suitability of clearing links to integrate the European ... consists inthe custody service Custody refers to the safekeeping of assets and the administration of these securities on behalf of intermediaries and investors Forthe purpose of this study, the ... to III implemented) Interviewees’ assessment ofthe Global Clearing Link Assessment of economies of scale and scope inthe Global Clearing Link Deriving the Global Clearing Link’s net supply-side...
... INDUSTRY SETTING 2.1 Definition of Clearing PURPOSE Sets the stage forthe research conducted in this study by providing relevant definitions, explaining the industry setting and clarifying the focus ... consists of nine main chapters (Chapters to 10) Chapter sets the stage forthe research by providing relevant definitions of clearing, indicating the value-added of CCP clearing and delivering insight ... descriptive analysis ofthe current state ofthe clearing industry set the stage forthe following analytical objectives: besides defining the efficiency of clearing and identifying ways in which to measure...
... complexity of measuring and quantifying the savings from the reductions in back -of ce costs, these savings are not analysed inthe context of this study Forthe purpose of this study, the indicator for ... clearing links affect the VPN is analysed in greater detail inthe remainder ofthe study Forthe purpose of this research, clearing links are classified and distinguished according to their business ... by the clearing member by bypassing other investment alternatives, i.e investing its capital elsewhere instead of having to dedicate it to the purpose of clearing The cost of capital is therefore...
... the back -of ce and IT infrastructure 140 Clearing Services for Global Markets transparent information sharing within the firm further complicates the task of managing and monitoring the all -in ... number of interviewees by group and location8 Source: Author’s own driving factors forthe interest shown by NCMs inthe subject ofthe research are further analysed inthe remainder ofthe study The ... varieties inthe answers provided inthe expert interviews in order to facilitate the interpretation ofthe collected data.16 To this end, categories for analysing the contents ofthe interviews...
... to assess the cost of capital, the interviewed clearing members might not have had in mind the full scope of these costs as defined in section 3.2.2.1 Furthermore, the cross-checking ofthe data ... (or interested in becoming active) in many markets; they maintain only a single direct clearing relationship with their domestic home clearing house To clear their transactions inthe other (foreign) ... seamlessly into the overall business ofthe clearer Outsourcing and offshoring in clearing usually pertain to non-core back -of ce and/or IT functions.118 The objective of outsourcing and offshoring is...
... ‘[c]hanges inthe size of an associated network’.11 A growing interest in investigating the relevance of network theory for analysing the organisation of financial markets has recently emerged inthe ... Learning effects positively impact both back -of ce and IT costs Another positive indirect network effect is the information effect The existence of a single counterparty reduces the level of information ... output increase.95 When valuating the input in factor prices, existence of economies of scale leads to a declining average cost curve The concept of economies of scale therefore describes a declining...
... houses inthe context of a clearing link set-up The analysis reveals that it is crucial forthe success of clearing link initiatives that the partnering CCPs endeavour to compensate forthe lost intermediary ... the largest clearing members as a result of their significantly streamlined operating efficiencies The findings ofthe analysis in Chapter reinforce the insights provided by the McP Curve, but they ... generally minimises the costs of interlinking forthe partnering CCPs and also translates into cost savings for clearing members To minimise the costs of implementing the link solution, three market...
... pressure/demand for utilisation ofthe link) further exacerbated the starting problem.128 r The installed bases and the starting problem inherent to the EU Link constituted weak forms of lock -in As outlined ... particularities ofthe clearing link; (ii) the resulting attractiveness of disintermediation through the clearing link; and (iii) whether decreases in revenues outweigh the efficiency gains The analysis ofthe ... open interest effect Since the launch ofthe EU Link, members ofthe ECAG network have benefited from the growing number of products cleared through the CCP; for some of these, cross-margining...
... i.e in charging insufficient levels of margin 409 The future network economy – developmentofthe clearing industry Besides increasing the efficiency ofthe European clearing industry, a clearing ... oppose a Single CCP unless they have a substantial say inthe governance ofthe clearing house and can in uence the rules of clearing This is the only way for them to circumvent the risk of disintermediation ... to analyse their customers’ usage patterns in detail The clearing link strategy for Europe should be formulated on the basis of these findings Forthe purpose of identifying the value of any particular...
... useful in this context The focus of this research was on analysing integration and harmonisation initiatives inthe clearing industry It was briefly outlined that the dynamics inthe clearing industry ... continue to dominate within the European clearing industry Clearing houses could profit immensely from the implementation of a clearing link initiative A link set-up would enable them to internalise ... particular link on to the market For CCPs, the key to formulating a successful European clearing link strategy is in knowing and understanding the needs and wants of their current and potential clearing...
... r Based on the assumptions regarding the composition ofthe all -in clearing costs forthe remaining 213 European clearers and the amount ofthe total clearing house charges per clearing member ... assumptions regarding the Value Provision Network, the structure ofthe European clearing industry and the composition of all -in costs ofthe six benchmark clearing members and the remaining 213 European ... Single CCP The calculation ofthe efficiency impact of European clearing links and a single European CCP was based on the results and method of calculation outlined in Appendix 7, including the...
... of clearing, indicating the value-added of CCP clearing and delivering insight into the various stakeholders in clearing An overview ofthe structural set-up ofthe European and US clearing industries ... optimising the use of collateral required for securing the trade The focus has therefore traditionally been on settlement rather than on clearing The main value-added of CCPs inthe context of securities ... threaten the viability ofthe world’s financial markets.224 Central banks therefore have a core interest in understanding the ways in which the increasing use of CCP services alter the distribution of...
... complexity of measuring and quantifying the savings from the reductions in back -of ce costs, these savings are not analysed inthe context of this study Forthe purpose of this study, the indicator for ... clearing links affect the VPN is analysed in greater detail inthe remainder ofthe study Forthe purpose of this research, clearing links are classified and distinguished according to their business ... by the clearing member by bypassing other investment alternatives, i.e investing its capital elsewhere instead of having to dedicate it to the purpose of clearing The cost of capital is therefore...
... the back -of ce and IT infrastructure 140 Clearing Services for Global Markets transparent information sharing within the firm further complicates the task of managing and monitoring the all -in ... number of interviewees by group and location8 Source: Author’s own driving factors forthe interest shown by NCMs inthe subject ofthe research are further analysed inthe remainder ofthe study The ... varieties inthe answers provided inthe expert interviews in order to facilitate the interpretation ofthe collected data.16 To this end, categories for analysing the contents ofthe interviews...