... http://www.jnrbm.com/content/6/1/1 10 Group I,II,III T4 Control T4 Day Day 40 Day 80 Group I,II,III TSH Control TSH 0.1 Figure TSH and T4 concentration on Day 0, 40 and 80 after RAI TSH and T4 concentration on ... 0.276 Figure TSH and T4 concentrations weeks after transplantation of stem cells TSH and T4 concentrations weeks after transplantation of stem cells TSH and T4 serum levels of all groups weeks after ... neurons Nonetheless, no studies report the use of BM cells in endocrine disorders like hypothyroidism [2,3] To investigate whether adult bone marrow cells are able to aid in the reconstitution of...
... statistically significant Results Effectsofbone marrow-derived cells on monocrotalineinduced pulmonary hypertension (PH) PH developed within 15 days of MCTp injection, as shown by a sustained increase ... muscularization of distal pulmonary vessels, compared to vehicle-injected animals (Fig 1) BMDCs injection days after MCTp injection reduced the increases in RVSP and RV/LV+S in a dose- Effectsofbone ... Detection of GFP-positive bone marrow-derived cells in lungs from recipient mice Immunohistochemical analysis of lung sections from control eGFP-positive mice revealed strong immunostain- Page of...
... Close-up view of the compartment of subchondral bone erosion, original magnification × 400 (c) Cortical bone channels underneath subchondral bone erosions, original magnification × 400 (d) Inflamed ... mm bone surface), both covering approximately 25% of the bone surface, indicating high but balanced boneturnover (Figure 3c,d,) In contrast, the endosteal surface distant from bone erosions contained ... endosteal bone surface distant from bone erosion, original magnification × 400 bone Synovial inflammation affects different compartments of juxta-articular bone H & E-stained sections from the...
... in which bone scan lesions were found to powerfully predict radiographic progression in the knees Onbone histology, areas ofbone affected by BMLs exhibit reversal lines indicative ofbone remodeling ... remodeling [10] Small areas ofbone necrosis are also present, as is scar The extensive bone remodeling seen, and the correlation of MRI bone marrow lesions with positive bone scintigraphy (a tracer ... properties of subchondral bone may play a role in the degeneration of cartilage [2], and adjoining trabecular changes are considered necessary for the progression of OA [3] In OA, bone has characteristic...
... the bone healing process; Authors' contributions The comparison of test and control groups indicates that bone healing was accelerated by the effect of magnetic fields in all the conditions analyzed; ... of the surgical bone cavity Distribution of screws and washers, outlining the borders of the surgical bone cavity A distance of 1.3 mm separates the washers over the surgical cavity, corresponding ... however, stronger neovascularization as well as osteoclastic and bone remodelling activities were observed On day 60, besides marked external configuration of the magnetic washers with cortical bone, ...
... differentiation of MSCs: Upon induction with adipocyte induction media cells showed adipocyte globules on oil red ‘O’ staining (D) Osteogenic differentiation of MSCs: Upon induction with osteogenic ... Foundation of Fujian Province of China (2008J0282) and by the professorial academic Foundation of Fujian Medical University (JS06077) Page of 10 Author details Department of Neurology, Union Hospital, ... percentage of positivity was mentioned in the brackets Liu et al Journal of Translational Medicine 2011, 9:105 http://www.translational-medicine.com/content/9/1/105 Page of 10 Figure Efficiency of gene...
... failure and abandonment of graft modification by demineralization and perforation[27] The orientation of perforations within the bony cortex and the ensuing effectson graft revitalization has yet ... integration Stevenson and Horowitz[40] defined successful cortical bone allograft incorporation as concurrent revascularization following resorption and substitution with host bone without the loss of ... 83A(7):971-986 Makley JT: The use of allografts to reconstruct intercalary defects of long bones Clin Orthop 1985, 197:58-75 Stevenson S, Horowitz M: The response to bone allografts J Bone Joint Surg Am 1992,...
... differentiation of MSCs: Upon induction with adipocyte induction media cells showed adipocyte globules on oil red ‘O’ staining (D) Osteogenic differentiation of MSCs: Upon induction with osteogenic ... Foundation of Fujian Province of China (2008J0282) and by the professorial academic Foundation of Fujian Medical University (JS06077) Page of 10 Author details Department of Neurology, Union Hospital, ... percentage of positivity was mentioned in the brackets Liu et al Journal of Translational Medicine 2011, 9:105 http://www.translational-medicine.com/content/9/1/105 Page of 10 Figure Efficiency of gene...
... http://www.josr-online.com/content/5/1/1 Page of 10 Table Study Characteristics of Selected Experimental Controlled Animal Studies on He-Ne Low Level Laser Irradiation EffectsonBone Healing Authors ... increase of periosteum cells function [18], increase of osetoblast and osteocyte function [18,19], new vascularistion [21,22], stimulation of enchondral ossification, earlier differentiation of mesenchymal ... http://www.josr-online.com/content/5/1/1 Page of 10 Figure Flow diagram for identification the eligible experimental control animal studies evaluating the effect of low power laser irradiation onbone healing based on...
... excessive consumption of other nutrients, such as protein and minerals, known to influence bone metabolism [71] Findings of the effectsof obesity onbone health in humans have been based on Cao ... outcome of obesity onbone health While research with obese animal model has established the negative effectsof adiposity onbone metabolism, studies with human subjects continue to be controversial ... Pennington C, Newton D, Xie D, Isales C: Leptin deficiency produces contrasting phenotypes in bones of the limb and spine Bone 2004, 34(3):376-383 Palacios C: The role of nutrients in bone health,...
... excessive consumption of other nutrients, such as protein and minerals, known to influence bone metabolism [71] Findings of the effectsof obesity onbone health in humans have been based on Cao ... outcome of obesity onbone health While research with obese animal model has established the negative effectsof adiposity onbone metabolism, studies with human subjects continue to be controversial ... Pennington C, Newton D, Xie D, Isales C: Leptin deficiency produces contrasting phenotypes in bones of the limb and spine Bone 2004, 34(3):376-383 Palacios C: The role of nutrients in bone health,...
... yltnacifingis GPA ,rotaludom -onummi na sA slevel esaerefsnartonima etatrapsa dna esarefsnartonima eninala eht ni segnahc yna esuac ton did dna ,yticixot citapeh tnacifingis wohs ton did GPA ,selamef dna ... elpitlum htiw )SOR( seiceps negyxo evitcaer fo epyt a , )ON( edixo cirtin dna ,ytinummi ralullec rof enikotyc evitatneserper a ,21-LI fo slevel ehT ON ton tub ,noitcudorp 21-LI desaercni yldekram GPA ... +4DC fo noitacifirup eht rof desu dna noitagufirtnec yb detsevrah erew sllec tnerehda-non ehT h rof )SBF( mures enivob latef %01 gniniatnoc aidem 0461 IMPR ni setyconelps eht gnitabucni retfa...
... Radioprotective effectsof an acidic polysaccharide of Panax ginseng onbone marrow cells J Vet Sci 2007, 8, 39-44 10 Kim MH, Joo HG Immunostimulatory effectsof fucoidan onbone marrow-derived dendritic ... cytokine production ofbone marrow cells (BMCs) The supernatants of BMCs were collected and ELISA was performed to quantify cytokine concentrations N/D: non-detectable level of cytokine Asterisks ... biological effectson natural killer cells [13], hematopoietic stem cells [6], endothelial cells [11], and DCs [10] Although the effectsof fucoidan on the mobilization of HPCs in bone marrow...
... support our observation on the accumulation of pre-germinal center B cells long after rituximab treatment Table Absolute numbers of B cells in bone marrow (per 106 mononuclear cells) Long-term CD27-IgD(Immature) ... did not achieve a complete depletion of B cells in BM [33] One of the possible explanations is a lack of or low intensity of CD20 expression on the surface of B cells Indeed, many B cell precursors ... population; or a depletion of B cell population potentially responsible for autoantibody secretion The long-term follow-up of rituximab effects shows no differences regarding the levels of circulating...
... Correlation of the development of knee pain with enlarging bone marrow lesions on magnetic resonance imaging Arthritis Rheum 2007, 56:2986-2992 Zanetti M, Bruder E, Romero J, Hodler J: Bone marrow ... progression of tibiofemoral cartilage defects, suggesting this is not sim- (b) Magnetic resonance images Figure Magnetic resonance images (a) Magnetic resonance image of knee showing no bone marrow ... English DR, Giles GG, Sullivan RO, FM C: Association ofbone marrow lesions with knee structures and risk factors for bone marrow lesions in the knees of clinically healthy, community-based adults...
... expression of leg weakness after five generations of selection were found to differ also in several traits of bones and muscles of the front leg Selection of pigs with different degrees of leg ... lesions were on the proximal humerus Weight and dimension values for various bones of the front leg are listed in table IV There were no significant line differences in the weights of the bones of ... significance of the differences ofbone dimensions other than length was not clear All dimensional changes in bone, other than length, occurred in the scapula and humerus, bones located above the level of...
... shell of most bones and it accounts for 80% of the total bone mass Cortical bone is mostly found in the shaft portion of long bones and the outer shell found around the spongy bone at the end of ... Secondly, bone surrounds blood in compact bone while blood surrounds bone in the cancellous boneOn a microscopic level, the structure ofbone can be distinguished into woven and lamellar bone based on ... woven bone by lamellar bone and the resorption of excess callus Gradual modification of the fracture region leads to restoration of normal bone architecture Figure 1.1: Schematic representation of...
... inhibitory effect of Dex on phosphorylation of JNK and p38 74 3.2.6.3 Inhibition of MKP-1 expression suppressed Dex-induced downregulation of MCP-1 mRNA expression in activated ... array of physiologic functions, such as muscle relaxation, immune modulation, and neuronal activity (Grisham et al 1999) As a free radical, NO is one of the major contributors to the formation of ... modulate the inflammatory response and proliferation index of microglia Hence, we have investigated the effectsof RA on release of proflammatory cytokines and proliferation in activated microglia...
... Activity 5.3 Effectsof DX On Efflux Of Sulfated Conjugates In Hep G2 Cells 5.4 Effectsof DX On Detoxification Via Sulfation Pathway 68 68 Conclusion 75 Future works 76 References 78 Abbreviations 98 ... conjugation -OH Condensation Various Table 1.1 Phase II conjugation reactions (Kauffman, 1990) 1.2 Sulfation 1.2.1 Sulfation: An Overview Sulfation plays a role in homeostasis and regulation of ... Detection: Effect Of DX On Xenobiotic Transporters 4.9 Software Analysis: Putative Promoter Elements Of The SULT1A3 Gene 40 40 40 44 Discussion 5.1 EffectsOfGlucocorticoidsOn Sulfation In Hep...
... direction of weight bearing as well as bone turnover, contributed by bone formation and resorption Data is accumulating that boneturnover markers may also complement the assessment for bone strength ... Although high concentration of PTH enhances osteoclastic resorption of bone, intermittent administration of PTH produces an anabolic effect in bones PTH stimulates bone formation in both cortical ... rate ofbone loss and turnover rate is lower [4] The underlying cause for osteoporosis is high bone resorption, and low BMD mesurement is a indicator of this condition The strength ofbone is...