drug extensively drug resistant tuberculosis mdr xdr tb renewed global battle against tuberculosis
Pulmonary rehabilitation in multi-drug resistant tuberculosis (TB MDR): a case report potx
... as a threat against the control of tuberculosis (Tb) in various parts of the world In Colombia, according to the WHO/OPS (2004), the estimated percentage of multi -drug resistant Tb in patients ... data reported on the estimated percentage of multi -drug resistant Tb in patients with previously treated Tb1 By 2005, nearly 10,000 cases of Tb were diagnosed, and approximately 15% of these were ... This report describes the deterioration of the functionality of a patient with multi -drug resistant Tb (MDR- TB) even to the point of such patient losing the ability to perform every-day activities,...
- 6
- 217
- 0
FACING THE REALITY OF DRUG-RESISTANT TUBERCULOSIS: CHALLENGES AND POTENTIAL SOLUTIONS IN INDIA pot
... of Drug- Resistant TB, Treating TB in Context, Overview of TB and MDR TB in India, Setting the Stage, 10 Organization of the Report, 11 DRUG- RESISTANT TB IN INDIA The Burden of TB and MDR TB in ... the Challenge of Drug- Resistant TB, 25 Potential Innovations and Action Items, 26 13 THE GLOBAL BURDEN OF DRUG- RESISTANT TB Overview of the Global Burden of TB and MDR TB, 29 MDR TB Prevention and ... CONTENTS ADDRESSING TB AND DRUG- RESISTANT TB IN VULNERABLE POPULATIONS Drug- Resistant TB in Pediatric Populations, 55 The Burden of Pediatric TB in Households of Patients with MDR TB, 58 Drug Resistance...
- 147
- 375
- 0
Managing drug resistant tuberculosis ppt
... to tuberculosis and drug resistance Drug resistant tuberculosis Tuberculosis that is resistant to any first line antituberculosis drug (see table 1) Multidrug resistant tuberculosis (MDR- TB) — ... resistant tuberculosis (MDR- TB) — Tuberculosis that is resistant to at least isoniazid and rifampicin Extensively drug resistant tuberculosis (XDR- TB) — Tuberculosis that is resistant to at least isoniazid ... treatment of multidrug resistant tuberculosis How can we prevent drug resistant tuberculosis? The principles of tuberculosis control are equally relevant to the prevention of drug resistant tuberculosis: ...
- 6
- 95
- 0
Addressing the Threat of Drug-Resistant Tuberculosis potx
... THREAT OF DRUG- RESISTANT TUBERCULOSIS Number of MDR TB and XDR TB Patients 300 250 200 109 146 150 100 50 113 126 63 XDR TB MDR TB 102 2005 2006 2007 Year FIGURE 2-6 Numbers of MDR TB and XDR TB patients ... DRUG- RESISTANT TUBERCULOSIS 1.00 MDR TB vs XDR TB Percent Survival 0.75 0.50 0.25 0.00 50 100 150 200 250 300 350 400 Days STRATA: TYPE =MDR TB TYPE =XDR TB Censored TYPE =MDR TB Censored TYPE =XDR ... THE GLOBAL SPREAD OF MULTIDRUG -RESISTANT AND EXTENSIVELY DRUG- RESISTANT TUBERCULOSIS Scope of the Problem, 19 Underreporting of MDR TB in Africa, 25 The Threat of Totally Drug- Resistant TB, 33...
- 253
- 296
- 0
Báo cáo y học: "Metaplastic ossification in the cartilage of the bronchus of a patient with chronic multi-drug resistant tuberculosis: a case report" potx
... Abbreviations AFB: acid-fast bacilli; COPD: chronic obstructive pulmonary disease; MDR: multi -drug resistant; TB: tuberculosis Competing interests The authors declare that they have no competing ... Metaplastic ossification in the cartilage of the bronchus of a patient with chronic multi -drug resistant tuberculosis: a case report Journal of Medical Case Reports 2010, 4:156 ... observations in case we describe here suggest that persistent stimulation by chronic inflammation in MDR- TB may occasionally induce the development of osseous metaplasia from the cartilage of the bronchial...
- 4
- 332
- 0
Báo cáo y học: " The Beijing genotype and drug resistant tuberculosis in the Aral Sea region of Central Asia" pot
... categories of drug resistance, by tuberculosis treatment status Total cases New cases Previously treated cases Fully susceptible Resistant to one drug only Poly -resistant (not MDR- TB) MDR- TB Total ... management of multidrug -resistant tuberculosis (MDR- TB) Geneva, Switzerland: WHO; 2000 WHO/CDS /TB/ 2000.279 Portaels F, Rigouts L, Bastian I: Addressing multidrug -resistant tuberculosis in penitentiary ... Poly -resistant (not MDR- TB) MDR- TB Total Fully susceptible Resistant to one drug only Poly -resistant (not MDR- TB) MDR- TB Total two M tuberculosis strains (Fig 1) These findings could be confirmed...
- 9
- 404
- 0
Báo cáo y học: " Phase IIb randomized trial of adjunct immunotherapy in patients with first-diagnosed tuberculosis, relapsed and multi-drug-resistant (MDR) TB" doc
... Contrary to TB drugs the efficacy of immunebased therapy on drug- resistant TB is considered to be the same as against drug- sensitive strains [34] In our hands V5 seemed to be equally effective against ... 34) Lower paired bars show conversion rates among first-diagnosed TB (1stDx); relapsed TB (RTB); and multidrug -resistant TB (MDR) respectively Butov et al Journal of Immune Based Therapies and ... Patients The study involved 18 first-diagnosed TB (1stDx; 52.9%), relapsed TB (RTB; 17.6%), and 10 patients with confirmed multi -drug resistant TB (MDR; 29.4%) The patient population comprised...
- 9
- 285
- 0
Radiological Findings of Extensively Drug-Resistant Pulmonary Tuberculosis in Non-AIDS Adults: Comparisons with Findings of Multidrug-Resistant and Drug-Sensitive Tuberculosis docx
... with DS TB was not significant Numbers in parentheses are percentages DS TB = drug- sensitive tuberculosis, MDR TB = multidrug -resistant tuberculosis, XDR TB = extensively drug- resistant tuberculosis, ... < 0.038 < 0.271 < 0.069 DS < MDR DS < MDR* DS < MDR = XDR DS < MDR* DS < MDR* DS = MDR < XDR Note.─ *XDR TB as compared with MDR TB or XDR TB as compared with DS TB is not significant Numbers ... are median, standard error and range DS TB = drug- sensitive tuberculosis, MDR TB = multidrug -resistant tuberculosis, XDR TB = extensively drug- resistant tuberculosis, GGO = ground-glass opacity...
- 10
- 460
- 0
Tài liệu Báo cáo khoa học: Amprenavir complexes with HIV-1 protease and its drug-resistant mutants altering hydrophobic clusters docx
... Fig 1B Multidrug -resistant mutation V32I, which alters a residue in the active site cavity, appears in 20% of patients treated with APV [14] and is associated with high levels of drug resistance ... mutation results in different structural changes with the two drugs Comparison of the structures provides insight into why I50V is a major drug- resistant mutation observed HIV protease mutants altering ... crystal structures of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017) active against multi -drug- resistant clinical strains J Mol Biol 338, 341–352 Mahalingam B, Boross P, Wang YF, Louis...
- 16
- 582
- 0
Herbal Antibiotics Natural Alternatives for Treating Drug-Resistant Bacteria doc
... page > Page 34 against strains of bacteria that are highly resistant to antibiotics Unlike many herbs, garlic is directly effective against viruses Garlic is perhaps the most extensively tested ... are many, a few of which are naturally immune or resistant to antibiotics Generally, these few resistant bacteria are in competition with their nonresistant cousins (and all the other helpful bacteria) ... they kill off the nonresistant disease bacteria (and often many or most of the other, helpful bacteria), leaving the resistant bacteria to reproduce without competition The resistant bacteria then...
- 180
- 557
- 0
Báo cáo hóa học: " Modeling the effects of drug resistant influenza virus in a pandemic" doc
... (which is either drug sensitive or drug resistant) is introduced into a fully susceptible population On day 21, a second introduction follows (again drug sensitive or resistant) Drug resistance ... the drug sensitive virus (solid lines in black), the drug resistant one (dashed lines) and the sum of Prevalence of infection with the drug sensitive virus (solid lines in black), the drug resistant ... on day and 21; (b) Drug sensitive infection is imported on day 0, followed by a drug- resistant one on day 21; (c) Drug resistant infection is imported on day 0, followed by a drug- sensitive one...
- 6
- 372
- 0
báo cáo hóa học:" Frequency of Drug-Resistant Variants of HIV-1 Coexistent With Wild-Type in Treatment-Naive Patients of India" pdf
... transmission of drug- resistant HIV strains would aid design of optimal drug regimens and clinical management Our study was designed to obtain preliminary data on the frequency of drug- resistant variants ... infected with subtype C live, there is very little information on drug resistance in HIV-infected people The frequency at which drug- resistant reverse transcriptase variants occur in evolving HIV-1 ... Caribbean, he prevalence of HIV strains with at least primary drug- resistant mutation is low (less than 7%), as evidenced by a few reports on drug resistance based on sequencing of the pol gene.[24-28]...
- 7
- 201
- 0
Báo cáo y học: "5''''PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication" pdf
... hr and then infected with (a&b) wild-type and drug- resistant human H1N1 viruses; (b&c) drug- resistant H3N2 viruses and (d&e) wild-type and drug- resistant B viruses Supernatants collected were ... the replication of drug- resistant A/ Vietnam/1203/2004 viruses that include zanamivir- and oseltamivir-sensitive and adamantanes -resistant and adamantanes- and oseltamivir -resistant virus variants, ... for cytoplasmic RNA sensor, RIG-I, in antiviral innate immune response against a panel of influenza viruses including drug- resistant, potential pandemic as well as pandemic strains in human lung...
- 11
- 240
- 0
Báo cáo khoa học: "Replication and drug resistant mutation of HIV-1 subtype B'''' (Thailand B) variants isolated from HAART treatment individuals in China" pot
... coculture The NRTI drug resistant mutations lost in strains after coculture, including T69APST, M41LM, and A62V One drug resistant mutation (L74V) changed to V75T The NNRTI drug resistant mutations ... replication properties of 13 drug- resistant variants using PBMC assay The data show all drug resistant variants were able to yield productive infections in PBMCs Suggested that drug- resistant HIV-1 isolates ... transmission of resistant HIV-1strains However, the drug resistant mutations in vitro in absence of drugs were persistent and only mutations were lost after passage suggested that the drug resistant...
- 6
- 270
- 0
Báo cáo y học: " Perinatal acquisition of drug-resistant HIV-1 infection: mechanisms and long-term outcome" potx
... risk of infection by drugresistant HIV-1 strains when the mother harbors such viruses or when drug pressure during MTCT prophylaxis is suboptimal Vertical transmission of drug- resistant HIV-1 was ... neonatal drug resistance profiles pointed to two different mechanisms of acquisition of resistant variants by infants in the perinatal period (Figure 4) First, the infant could acquire drugresistant ... P225H, M230L, and P236L Mixtures of WT and mutant sequences were considered drug- resistant Interpretation of genotypic drug susceptibility was done according to the 2007 French ANRS algorithm http://www.hivfrenchresist...
- 13
- 204
- 0
Báo cáo y học: " Highly diversified multiply drug-resistant HIV-1 " pps
... existence of large quasispecies can serve as reservoirs for the emergence of viral species resistant to different drugs, since infected cells might survive for several years [20,21] Our results on uncultured, ... JI, Terlecky SR, Wawrzak Z, Winters MA, Merigan TC, Kovari LC.: Crystal structures of a multidrug -resistant human immunodeficiency virus type protease reveal an expanded active-site cavity J ... occurred more slowly in this region than in the similarly sized PR region, reflecting differences in drug selection pressure Although RT inhibitors have been reported to affect RNase H, no mutations...
- 6
- 104
- 0
Báo cáo y học: " Tenofovir treatment augments anti-viral immunity against drug-resistant SIV challenge in chronically infected rhesus macaques" pot
... emergence of drug- resistant HIV-1 [4] Drug- resistant strains of HIV-1 harbor mutations that can negatively impact viral fitness, but these viruses gain a replicative advantage in the presence of drug ... found drug resistance mutations [9,10], suggesting that immune recognition is adaptive and responsive to the emergence of drug- resistant virus Whether these responses control replication of drugresistant ... replication of drug- resistant virus The macaques in this study were treated with tenofovir for weeks prior to challenge with drug- resistant SIV While tenofovir has direct antiviral effects against SIV...
- 13
- 143
- 0
Báo cáo y học: "Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy" ppsx
... amplified DNA in drug- resistant Leishmania exists as extrachromosomal circles Science 1986, 233:535-540 Dewes H, Ostergaard HL, Simpson L: Impaired drug uptake in methotrexate resistant Crithidia ... Hehlmann R: Cancer drug resistance: the central role of the karyotype Drug Resist Updat 2007, 10:51-58 Selmecki A, Forche A, Berman J: Aneuploidy and isochromosome formation in drug- resistant Candida ... without changes in copy number of a gene is an infrequent event in drug resistant Leishmania The use of both L infantum and L major MTX resistant mutants validated the design of our multi-species array...
- 16
- 299
- 0
Multiple antibiotics in combination against extreme drug resistant acinetobacter baumannii in an in vitro pharmacokinetic pharmacodynamic model
... of drug A = MIC of drug A in combination/MIC of drug A alone, FIC of drug B = MIC of drug B in combination/MIC of drug B alone The FICI was defined as the FIC of drug A added to the FIC of drug ... Mean UPLC: ultra-pressure liquid chromatography V: volts VUP: volumes under the planes XDR: Extensively drug resistant 33 56 54 101 55 57 52 53 113 101 23 52 31 41 53 56 33 18 54 54 16 CHAPTER Introduction ... this group of organisms Multidrug-resistance is defined as nonsusceptibility to at least one agent in three or more antimicrobial categories Extensively drug resistance (XDR) is defined as non-susceptibility...
- 149
- 322
- 0
Tài liệu THE MANAGEMENT OF MULTIDRUG RESISTANT TUBERCULOSIS IN SOUTH AFRICA docx
... MANAGEMENT OF MDR TUBERCULOSIS i Multidrug Resistant TB is defined as TB disease where there is demonstrated resistance to both INH and rifampicin with or without resistance to other anti -TB drugs As ... retreatment patients and patients with MDR TB, it will make a major contribution to the limitation of MDR TB THE DIAGNOSIS OF MDR TUBERCULOSIS • • • • • MDR TB is a laboratory diagnosis It should ... CONTACTS OF MDR TUBERCULOSIS PATIENTS 18 HEALTH CARE WORKERS AND MULTIDRUG -RESISTANT TUBERCULOSIS 19 15.1 TRANSMISSION OF TUBERCULOSIS 19 15.2 PATHOGENESIS OF TUBERCULOSIS...
- 28
- 459
- 0
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25