dose response and dose effect curves to assess the in vitro toxicity optimization of the experiments
Báo cáo y học: " Sodium nitroprusside and peroxynitrite effect on hepatic DNases: an in vitro and in vivo study" potx
... aspect of apoptosis is the universal property of some proteins to exert a dual function: the protection against proteolysis and the maintenance of the structure and function of normal cells Being ... After in vitro exposure of isolated hepatocytes to SNP or peroxynitrite, the activity of both alkaline and acid DNase decreased in a dose- dependent fashion (Figure 2) During in vitro incubation of ... injection under penthobarbital sodium anesthesia The concentrations were calculated according to the literature data concerning their in vivo tolerability and in vitro ability to induce apoptotic...
- 9
- 361
- 0
Báo cáo khoa học: "A pilot study to assess the feasibility of evaluation of markers of response to chemotherapy at one day & 21 days after first cycle of chemotherapy in carcinoma of breast: a prospective non-randomized observational study" potx
... using Caspase-3 to evaluate the apoptotic index, as this terminal enzyme of the apoptotic cascade is cytoplasmic in location This led to a diffuse staining of slides, which caused difficulty in ... paraffin and sectioned into μm-thick sections Surgery was scheduled after completion of 2–6 cycles of PCT according to patient's response to chemotherapy and at discretion of the treating physicians ... available in the hospital along with feasibility to evaluate biomarkers of response to chemotherapy in these biopsies The correlation to response, if proven, would help clinicians to tailor chemotherapy...
- 11
- 393
- 0
Báo cáo khoa học: "A phase I radiation dose-escalation study to determine the maximal dose of radiotherapy in combination with weekly gemcitabine in patients with locally advanced pancreatic adenocarcinoma" doc
... achieved by increasing the fraction size in increments of 0.2 Gy, keeping the duration of radiation constant at weeks The starting dose was 30 Gy (in Gy fractions) and the final dose investigated ... manage local toxicity presented in body areas in the radiation volumes, especially in case of grade or adverse events involving small and large intestine If the toxicity reduced to grade or 2, ... cohort and 11.88% ± 5.26 in the 54 Gy cohort; p = 0.006) and also in cumulative GI toxicity (p = 0.027) There was no grade toxicity in the 45 Gy cohort versus grade toxicity events in the 54...
- 7
- 433
- 0
Báo cáo y học: " Relatives Education And Coping Toolkit - REACT. Study protocol of a randomised controlled trial to assess the feasibility and effectiveness of a supported self management package for relatives of people with recent onset psychosis" pdf
... call the day before the interview to check the appointment time is convenient and to reiterate the need to maintain blindness RA1 conducts all of the follow-up interviews and remains blind to allocation ... Page of and their preferences for how this should be delivered, including format of the toolkit and type and amount of support required to use it Barriers and facilitators to using the toolkit and ... delivery of the support LW contributed to design of the intervention, recruits and assesses participants, and manages the process of randomisation; VP contributed to the design of the intervention and...
- 7
- 305
- 0
Applying house's translation quality assessment model to assess the Vietnamese translation of Mark Twain’s The Adventures of Huckleberry Finn -chapter XX and it105920
... the novel in a given setting In order to standardizing the dialects in the novel, the translator seemed to focus on the words in the text and their meaning within the story Therefore, the plot ... necessity to assess a translation in terms of the appropriateness of the translator‘s intention to that of the author of the original, not of the appropriateness of the translator‘s intention to that ... thật to. ‖ vs and went weaving first to one side of the platform and then the other, and then a leaning down over the front of it, with his arms and his body going all the time, and shouting his...
- 118
- 694
- 1
Tài liệu Báo cáo khoa học: "ENGLISH WORDS AND DATA BASES: HOW TO BRIDGE THE GAP" pdf
... DBL independently of each other (one on the basis of the possible English questions about the subject-domain, the other on the basis of the structure of the data base about it) there must be a ... then be derived on the basis of a specification of the relation between the English word meanings used in (i) and the primitive concepts at the data base level IV V THE RELATION BETWEEN EFL AND ... denoting a set, and n functions Al, , An which have the denotation of K as their domain ~ At the most global level of description, the PHLIQA system can thus be thought to consist of the following...
- 3
- 498
- 0
Occupational therapy interventions and physical activity interventions to promote the mental wellbeing of older people in primary care and residential care pdf
... working with older people Training schemes should include: − essential knowledge of (and application of) the principles and methods of occupational therapy and health and wellbeing promotion − effective ... life All the activities are intended as starting points; they should be tailored to meet the needs of the participants, as opposed to the activities dictating the group The organisation of themes ... effectiveness of interventions depends on the status or characteristics of those delivering the intervention), on the involvement of older people in their design and delivery, or on the involvement of family...
- 50
- 743
- 0
Báo cáo khoa học: The signature amidase from Sulfolobus solfataricus belongs to the CX3C subgroup of enzymes cleaving both amides and nitriles Ser195 and Cys145 are predicted to be the active site nucleophiles pot
... activating Ser171 (Fig 5B) One of its amino ˚ groups is about 2.6 A from the Oc atom of Ser171 ˚ and 2.5 A from the thiol group of Cys145 4720 Even taking into account all of the limitations of molecular ... increased occupancy deriving from the arginine side chain in position 96 might modulate the size of the cleavable substrates (Fig 4) Furthermore, the amino group of Arg96 could coordinate a water molecule ... correctly positioned to perform catalysis with the Oc ˚ atom of Ser171 at about 2.8 A from the Oc atom of ˚ Ser195 and about 2.7 A from the amino group of Lys96 4718 The analysis of the structural...
- 9
- 478
- 0
Money and happiness a guide to living the good life
... as men to live their retirement years in poverty, and twice as likely to live in a nursing home, according to the Administration on Aging • More than half of the elderly widows now living in poverty ... friends understood why I was studying theology Few of my peers in the master’s program (most of them ministers in training) understood why I was interested in Wall Street I lived in a dualistic ... selling the landmark arts -and- crafts-style home she treasured “I drew a line in the sand and said, ‘We’re in debt and we’re not going to get into any more debt.’ It was a tense time My husband...
- 258
- 358
- 0
Báo cáo khoa học: The use of recombinant protein and RNA interference approaches to study the reproductive functions of a gonad-stimulating hormone from the shrimp Metapenaeus ensis ppt
... antibody to vitellogenin [27] The lower panel shows the Coomassie blue staining of the hemocyanin (Hcy) corresponding to the same protein samples (D) Left: relative levels of vitellogenin in ovary of ... information on the initial mechanism of hormone action In other words, the in vitro results indicate that MeMIH-B may act directly on the hepatopancreas and ovary to increase the rate of vitellogenin gene ... amount of dsRNA injected in the animal may vary, depending on the expression level of the gene; a much higher dose of dsRNA was injected into the shrimp L schmitti to silence the CHH gene [26] In...
- 11
- 546
- 0
.Get More and Do More at Dummies.com ®Start with FREE Cheat SheetsCheat Sheets include • Checklists • Charts • Common Instructions • And Other Good Stuff!To access the Cheat Sheet created specifically for this book, go towww.dummies.com/cheatsheet/e pptx
... rap, too, especially for the role they played in the infamous “flash crash” of May 6, 2010 (see Chapter 2) and for the ongoing role they are playing in the increasingly nauseating volatility of the ... origins of ETFs ▶Understanding their role in the world of investing today ▶Getting a handle on how they are administered ▶Finding out how they are bought and sold ▶Tallying their phenomenal growth ... Forcing down prices on other investment vehicles You don’t need to invest in ETFs to profit from them They are doing to the world of investing what Chinese labor has done to global manufacturing...
- 387
- 1,980
- 0
Promoting Student Health and Wellbeing: A guide to drug education in schools ppt
... those of others Thinking and critical thinking • • • • • Decision-making Understanding consequences and predictive thinking Shaping actions around situations involving drugs to improve wellbeing and ... separate or stand-alone They are the keys to learning in every learning area 15 Developing and sustaining a school culture of health and wellbeing Addressing the harmful effects of young people’s ... Understanding the need for buddies in social situations Understanding the importance of reassurance and cooperation in safety situations Ensuring the safety of others Participating and contributing...
- 45
- 597
- 0
nanophysics and nanotechnology an introduction to modern concepts in nanoscience
... breaking the class into interdisciplinary working groups who then prepare term papers and presentations that explore more deeply topics of their choice within the wealth of interesting topics in the ... directed along the sandwich in the direction transverse to the track, and the voltage across the sandwich, which is sensitive to the magnetic field in the plane of the sandwich, is measured In this ... coil and of the wire, lS is the shear modulus and , the total length of the wire [1] This spring constant K scales in three dimensions as L1 Insight into the typical scaling of other kinetic parameters...
- 301
- 461
- 0
báo cáo hóa học:" Bioactivity-guided identification and cell signaling technology to delineate the immunomodulatory effects of Panax ginseng on human promonocytic U937 cells" potx
... be due to the combinatorial effect of ginsenosides Inhibition of TNF-α-activated signal transduction pathways by PGSE To investigate the underlying mechanisms of the suppressive effect of the PGSE ... by using the Affymetrix GCOS and Genespring GX softwares as described in Methods To increase the stringency of the analysis, we combined the gene lists from the two software analyses Only the ... in ginseng, we examined the composition of ginsenosides in PGSE by HPLC analysis and the results are shown in Figure The calibration curves of the standard solutions containing 0.5–6.5 μg of each...
- 10
- 500
- 0
Báo cáo sinh học: " Recombinant HPV16 E7 assembled into particles induces an immune response and specific tumour protection administered without adjuvant in an animal model Linda Petrone1, Maria G Ammendolia2, Armando" ppt
... are indicated on the left and the E7 isoforms are indicated on the right HPV16 E7 contains a Zinc finger-like domain that binds the metal even when the protein is expressed in E coli [10,11] Since ... isotype profile indicates that the immune response induced in vaccinated mice is a mixed Th1/ Th2 type To analyse the induction of the cell-mediated immune response in mice after 1, or doses of the ... western blotting in reducing and nonreducing SDS-PAGE In the reducing gel, the E7 protein appears in monomeric form (Figure 1, lane 1) In nonreducing gels, based on the analysis of the molecular...
- 9
- 276
- 0
báo cáo hóa học:" Recombinant HPV16 E7 assembled into particles induces an immune response and specific tumour protection administered without adjuvant in an animal model" doc
... are indicated on the left and the E7 isoforms are indicated on the right HPV16 E7 contains a Zinc finger-like domain that binds the metal even when the protein is expressed in E coli [10,11] Since ... isotype profile indicates that the immune response induced in vaccinated mice is a mixed Th1/ Th2 type To analyse the induction of the cell-mediated immune response in mice after 1, or doses of the ... western blotting in reducing and nonreducing SDS-PAGE In the reducing gel, the E7 protein appears in monomeric form (Figure 1, lane 1) In nonreducing gels, based on the analysis of the molecular...
- 9
- 307
- 0
báo cáo hóa học:" The effect of abductor muscle and anterior-posterior hip contact load simulation on the in-vitro primary stability of a cementless hip stem" ppt
... Similarly, the effect of increasing Fap was mainly seen in the no abductor group Without the abductor, increasing Fap from to 0.3 BW increased the translational micromotion only in the lateral ... Axial and torsional loading of the actuator produced distal (Fd), medial (Fm) and anterior-posterior (Fap) loading of the femoral head due to the mounting geometry and the offset between the femoral ... shown to have the most pronounced effect on femoral strains, increasing medial bending in the proximal femur during gait [26-28] There are, however, contradictory results concerning the effects of...
- 14
- 400
- 0
Báo cáo lâm nghiệp: "SHORT COMMUNICATION The use of cotyledon proteins to assess the genetic diversity in sweet holm oak" potx
... degree of polymorphism, finding up to 32 polymorphic bands in all the trees evaluated On the other hand, the understanding of the genetic diversity presents in a species and the distribution of this ... according to the method described by Fonseca et al (1997) Four fractions (albumins, globulins, prolamines and glutelins) were obtained, all of them were precipitated with ml of cold acetone, and the ... frequencies of each band are shown in Table 1 The classification of Marshall and Brown (1975) was used to assess the distribution of alleles in different populations In general, the bands presented...
- 6
- 343
- 0
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25