do systemic factors modify the host response to plaque around implants
LX Thuy_tính toán vỏ có lỗ giảm yếu và gân gia cường chịu sóng xung kích: Effect of Some Factors on the Dynamic Response of Reinforced Cylindrical Shell with a Hole on Elastic Supports Subjected to Blast Loading
... Deflection response w with various values of hg American Journal of Civil Engineering 2016; 4(6): 306-313 assessment of the influence level of these factors to the dynamic response of the mentioned ... seat connection, so when the stiffness of the shell increases making more load transfers to the elastic seating which leads to the increase of the total displacement of the calculated point In ... , s e t1 (4) t0 ({q },{qɺ }, t ) is the Hamilton e function, Te is the kinetic energy of the element, Ue is the total potential energy of the element, We is total external { }{ } e e [ M ']es...
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Báo cáo khoa học: The autophagic response to nutrient deprivation in the hl-1 cardiac myocyte is modulated by Bcl-2 and sarco⁄endoplasmic reticulum calcium stores ppt
... autophagy in a population of cells Autophagic response to nutrient deprivation Autophagy is strongly upregulated in response to nutrient deprivation [19,29] To examine the autophagic response to ... lysosomal activity to quantify autophagic flux During the initiation of autophagy, cytosolic LC3 (LC3-I) is cleaved and lipidated to form LC3-II [16,20] LC3-II is then recruited to the autophagosomal ... conjugation systems The first is the conjugation of Atg12 to Atg5 [15] The other is the processing of the microtubule-associated protein light chain (LC3) Upon activation of autophagy, cytosolic LC3-I...
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The Consumer Response to Food Labeling
... Ranchers unable to document the history of their animals two years from now, including those being born right now, will find themselves unable to sell to supermarkets forcing their beef into the export ... named products The future of the EU policy is then discussed, in relation to the changes in the international framework Indeed, the status of the EU labeling system relative to the international ... compete on the health reasons to choose one fat over another Under the rules implementing the NLEA, health claims are limited to foods that are “best” on the dimensions relevant to the particular...
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báo cáo hóa học:" Validation of a flow cytometry based chemokine internalization assay for use in evaluating the pharmacodynamic response to a receptor antagonist" potx
... day period there is relatively little change in the overall expression of the CCR2 receptor as well as the cell's capacity to internalize the ligand The inter-person reproducibility of the assay ... internalization of AF488-MCP-1 by the receptor antagonist a direct comparison of the effect of overnight storage on the IC50 of the CCR2 inhibitor was examined Briefly, receptor antagonist was incubated ... AF488-MCP-1 from the 10 different donors' blood drawn at different times (each individual drawn times) The blood draws were spaced 2–4 days apart to allow for recovery of the donor prior to the next...
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Báo cáo y học: "Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGF-1 in cultured rat nucleus pulposus cells" ppsx
... At the same time, these investigators suggested that TGF is a bifunctional regulator of cellular growth [19,20] Considering these findings, we hypothesized that the cells that show mitogenic response ... was therefore to reveal the role of c-Myc in mitogenic response to TGF1 in nucleus pulposus cells The study was designed to (1) analyze the effect of TGF1 on cell proliferation and the cell cycle ... Although the percentages of cells in the S phase differ among individuals, these inhibitors both seem to block the mitogenic effect of TGF1 completely The statistical significance by the repeated...
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Báo cáo y học: "Mactinin: a modulator of the monocyte response to inflammation" pps
... role in the pathogenesis of chronic arthritis [8] The release of proinflammatory cytokines, chemokines, growth factors, and enzymes by the synovial lining macrophages is important for the onset, ... glutathione The fusion protein was then cleaved with thrombin (Calbiochem, San Diego, CA) to yield the actin-binding domain of α-actinin and the GST carrier The cleavage products were then separated ... and the level needed for chemotactic activity (0.5 nM or 15 ng/ml) The lack of mactinin in rheumatoid arthritis fluid was surprising, and we decided to pursue this further Owing to the autoimmune...
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Báo cáo y học: " Characterisation of the immune response to type I collagen in scleroderma" pps
... confirmed by other investigators [16] The study of antigen-specific lymphocytes is challenging because these cells are rare in the peripheral blood Recently, a flow cytometric method that allows the concurrent ... concurrent analysis of the phenotype and proliferative response of antigen-specific T cells was used to study the immune response to a specific antigen [17] We employed a similar method to demonstrate ... an immune response to CI in vitro, except for a trend toward more lung fibrosis in the CI responders Of the CI responders, 87.5% had pulmonary involvement, whereas only 47% of the Furthermore,...
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Báo cáo y học: "olutionary divergence in the fungal response to fluconazole revealed by soft clustering" pptx
... http://genomebiology.com/2010/11/7/R77 laboratory strains used as starting material The second reason relates to the environment: it is very difficult to mirror in the laboratory the range of conditions that ... fluconazole dosages [20], we exposed each species to fluconazole at its 50% inhibitory concentration to facilitate direct comparison of the transcriptional response between species We then monitored ... biosynthesis, the most conserved pathway response Interestingly, this pathway includes isoprenoid biosynthesis, for which the response was one of the most divergent (d) mRNA expression responses...
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báo cáo khoa học: " Public health the leading force of the Indonesian response to the HIV/AIDS crisis among people who inject drugs" doc
... (two of the main provinces of Indonesia) is to lead the response and use the infrastructure of the health system to scale the response to the level of the epidemic The expansion was based on a successful ... addition to the Indonesian government sectors, the international community is involved in the country's HIV/AIDS response Indonesia received $64 million US from the fourth round of the Global ... closely with the Ministry of Health to assist the Indonesian national response At the national level in the harm reduction field is the National Narcotic Board (BNN), which is attached to the National...
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Báo cáo khoa học: "PreS1 epitope recognition in newborns after vaccination with the third-generation Sci-B-Vac™ vaccine and their relation to the antibody response to hepatitis B surface antigen" potx
... [21,22] To further analyse the specificity and significance of the antibody responses toward the two linear preS1 sequences that have been shown to represent human B cell epitopes within the hepatocyte ... difference in response to the preS1 epitopes was noted in newborns immunised with the 2.5 ug or the 5.0 ug vaccine doses The mean levels of anti-HBs were significantly higher in the anti-preS1 ... whereas the N-terminal part is believed to play a major role in mediating virus attachment and entry into hepatocytes [3] Within the preS1 protein, the 21–47 amino acid epitope was shown to mediate...
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Báo cáo y học: " Reproducibility of the airway response to an exercise protocol standardized for intensity, duration, and inspired air conditions, in subjects with symptoms suggestive of asthma" pdf
... before the first FEV was measured We excluded those who were symptomatic to the allergens to which they tested positive to a skin test at the time to reduce variability due to environmental factors ... reproducibility of the exercise response in relation to the different NAEPPII scores is given in Table There was no relationship between the NAEPII score and the severity of the response to exercise ... children There was no significant difference between the HR % predicted and estimated ventilation % MVV between the test on the day the highest % fall in FEV1 was documented, and on the test on the...
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Báo cáo y học: " Private specificities can dominate the humoral response to self-antigens in patients with cryptogenic fibrosing alveolitis " pps
... Plaques were scored positive by visual inspection and in relation to the each of the other plaques on the membrane We screened sera from 11 other patients with CFA, nine patients with sarcoidosis, ... revealed the existence of multiple epitopes in the protein [14] Interestingly, the authors of that study noted a correlation between the type of epitope and the disease duration, supporting the hypothesis ... exhibit reactivity to only one of the synthetases, but different subsets have occasionally been recorded together in the same patient [17] Of interest, autoantibodies to synthetases have been...
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Báo cáo y học: " Beyond the first 25 years: The International AIDS Society and its role in the global response to AIDS" pps
... linkages and dialogue, and to strengthen the focus on youth – began to be implemented in the planning for the XVI International AIDS Conference (AIDS 2006) in Toronto and will be implemented ... looking forward to strengthening our engagement with the scientific community, while we build new partnership with NGOs, activists and others working on the frontlines of the response The IAS encourages ... research can be rapidly applied to practice The IAS is committed to continuously improving the conferences and strengthening their role beyond three or five-day events to become part of an ongoing...
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Báo cáo y học: "The effect of exogenous glucagon-like peptide-1 on the glycaemic response to small intestinal nutrient in the critically ill: a randomised double-blind placebo-controlled cross over study" pot
... critically ill patients has hitherto not been evaluated The primary aim of this study was to determine whether exogenous GLP-1 attenuates the glycaemic response to small intestinal nutrient infusion ... Discussion This is the first study to evaluate the effect of exogenous GLP1 infusion on the glycaemic response to enteral nutrition during critical illness Given the need to avoid hyperglycaemia ... concentrations were measured, as GLP-1 is not known to alter the secretion of the other counter-regulatory hormones and the study was designed to establish proof of concept [9] Exogenous GLP-1...
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Báo cáo y học: "Exogenous glucagon-like peptide-1 attenuates the glycaemic response to postpyloric nutrient infusion in critically ill patients with type-2 diabetes" ppsx
... contributions AMD was the co-contributor to study design, the acquisition, analysis and interpretation of the data and drafting the manuscript MH was the cocontributor to study conception and ... determine response to GLP-1 [23] We were unable to determine which factors predicted glucose-lowering in this small sample The mechanism(s) underlying the glucose-lowering that occurs with GLP-1 in the ... drugs during the study The maximal, or near-maximal, endogenous counter-regulatory hormonal response and administration of exogenous catecholamines are likely to affect glucose tolerance adversely...
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Báo cáo y học: "The genomic response to 20-hydroxyecdysone at the onset of Drosophila metamorphosis" ppsx
... indicating the highest level, as depicted on the bottom The numbers at the top indicate hours relative to pupariation, with green bars representing the peaks of 20E titer A high titer pulse of 20E at the ... coordinately downregulated at pupariation (Figure 3c) Interestingly, we identified both the Toll ligand-encoding gene dorsal and the key Toll effector gene spätzle as downregulated at the onset ... prepupae, in apparent response to the late larval 20E pulse, while many genes downregulated by 20E are repressed at these times The downregulated 20E-final genes that peak in to hour prepupae could...
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Characterization of the cellular response to hypoxia
... comparable effect on mTORC1 activities in all cell lines Taken together, these results strongly suggest REDD1 does not play a role as the key mediator of the rapid response of mTORC1 to hypoxia and ... and inhibit the TSC1/2 complex, thus leading to mTORC1 activation In the second pathway, presence of amino acids leads to the Rag-GTPases-Ragulator dependent translocation of mTORC1 to the lysosomal ... acids, mTORC1 is activated by the Rag GTPases and the Ragulator complex through its translocation to the lysosomal surface where mTORC1 is activated by Rheb (Sancak et al., 2010) Figure The mTORC1...
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Báo cáo y học: " Factors affecting the long-term response to tacrolimus in renal transplant patients: Pharmacokinetic and pharmacogenetic approac"
... 2010, factors, the role of biological factors affecting the drug absorption, distribution, metabolism or deletion has been investigated [1-9] Till now, the most significant biological factors ... taken into account [7] The aim of the present study was to 95 determine the impact of CYP3A5*1 and CYP3A5*3 genotype on the kinetics of tacrolimus in renal transplant recipients The drug dose and ... factors) Categorical factors are used to divide study population into subgroups (between-subjects factors) and 96 continuous variables are used as control variables (covariates) Taking into account...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25