do ecp blood serum levels correlate with disease activity and mucosal hyperreactivity
Báo cáo y học: "Association of elevated transcript levels of interferon-inducible chemokines with disease activity and organ damage in systemic lupus erythematosus patients" docx
... peripheral blood cells were closely associated with disease activity and organ damage in SLE, and may be useful in disease monitoring and prognostication Materials and methods Patients and control ... mg/day) For each patient, disease activity and disease- related damage were assessed at the time of blood donation using the SLE Disease Activity Index 2000 (SLEDAI-2K) [16] and the Systemic Lupus ... Association of chemokine and IFN scores with disease activity in SLE patients Each symbol represents an individual patient; horizontal lines indicate and IFN scores with disease activity in SLE patients...
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Báo cáo y học: "Serum levels of autoantibodies against C-reactive protein correlate with renal disease activity and response to therapy in lupus nephritis" pps
... level and disease activity as reflected by the SLE disease activity index, anti-dsDNA antibody levels, and complement levels [12] The anti-CRP assay has been shown to be antigen-specific [17], without ... Anti-CRP antibody levels have previously been found to correlate with disease activity, but the present study is the first to show an association with renal disease activity assessed with the BILAG ... antibody levels paralleled disease activity, particularly in individuals with lupus nephritis [27] The authors also studied renal histopathology and found that anti-CRP antibody levels correlated with...
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Báo cáo khoa học: Amyloid-b protofibril levels correlate with spatial learning in Arctic Alzheimer’s disease transgenic mice docx
... Ab protofibril levels and total Ab levels in tg-ArcSwe mice (A) Levels of protofibrils in nontransgenic (non-tg) and tg-ArcSwe mice at (n = 6), (n = 9), 10 (n = 11), 14 (n = 10) and 17 (n = 6) ... Lord et al A B Fig Ab levels in tg-ArcSwe mice without plaque pathology and their relation to spatial learning Ab protofibril levels in NaCl ⁄ Tris extracts and total Ab levels in formic acid ... with food and water ad libitum The experiments were approved by ethical committees and performed in compliance with national and local animal care and use guidelines (protocols #C258 ⁄ and #C242...
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báo cáo hóa học: " Inflammatory cytokine levels correlate with amyloid load in transgenic mouse models of Alzheimer''''s disease" potx
... soluble and insoluble Aβ levels within and between genotypes The TgAPPsw and PS1/APPsw mice express equal levels of the APPsw molecule, but the PS1/APPsw model produces greater levels of Aβ and develops ... IL-12p40 showed the strongest correlation with levels of both Aβ1–40 and 42 (soluble or insoluble) IL1α and IL-1β were also highly correlated with Aβ1–40 and 42 (soluble or insoluble) tion [6,7] ... correlation of Aβ-cytokine levels Levels of soluble and insoluble Aβ1–40 correlated well with each other, and the same was observed for Aβ1–42 As expected, quantification of Aβ levels generally revealed...
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Báo cáo y học: "Serum levels of autoantibodies against monomeric C-reactive protein are correlated with disease activity in systemic lupus erythematosus" potx
... found between anti-CRP levels and several clinical and laboratory disease activity measures, namely serum levels of anti-DNA antibodies, complement factors C1q, C3 and C4, and SLEDAI scores, regardless ... one occasion and negative on another [25] This raised the question of whether anti-CRP levels might vary over time and be associated with disease activity or flares, and/ or certain disease manifestations ... laboratory disease activity measures on both individual and collective bases With accumulated data, positive correlations were found for SLEDAI, mSLEDAI and anti-dsDNA antibody levels, and significant...
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Báo cáo y học: "Effects of lamivudine on serum albumin levels correlate with pretreatment HBV-DNA levels in cirrhotic patients" pot
... albumin (A), and Δ-ALT and Δ-albumin treatment and ΔCorrelation Correlation between ALT levels before treatment and Δ-albumin (A), and Δ-ALT and Δ-albumin (B) In patients whose serum ALT levels were ... start of treatment, serum albumin levels increased rapidly and simultaneously with a decrease in HBV-DNA and serum ALT levels The data represent mean + SD (a, b; p < 0.05 and p < 0.01 vs month, ... ΔALT is within a narrower range and ALT levels cannot influence albumin levels significantly Figure (A), and Δ-HBV-DNA levels before treatment and Δ-albumin Correlation between HBV-DNA and Δ-albumin...
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Báo cáo y học: "Serum levels of biomarkers of bone and cartilage destruction and new bone formation in different cohorts of patients with axial spondyloarthritis with and without tumor necrosis factor-alpha blocker treatment" ppt
... Correlation of clinical parameters with serum levels of VEGF, MMP-3, and BALP in patients with spondyloarthritis We correlated the serum levels of VEGF, MMP-3, and BALP to clinical parameters in ... with CRP, ESR, and BASDAI (respectively) [17] or with ESR and BASDAI but not with CRP [27] We obtained no clear correlation of serum levels of BALP with parameters of disease activity Besides ... correlation of VEGF with CRP, ESR, and BASDAI This is in line with previous reports showing that VEGF is a good indicator of high disease activity in patients with AS [14,24,25] VEGF serum levels were...
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Báo cáo y học: "Collagen-specific T-cell repertoire in blood and synovial fluid varies with disease activity in early rheumatoid arthritis" pot
... Materials and methods Patients The demographic and clinical characteristics of six patients with RA who were analyzed at the onset of the disease, six patients with longstanding RA and receiving ... allowing us to obtain blood and synovial fluid samples, and she received specific therapy and modification to her therapy over time Samples for immunoscopy analysis (peripheral blood and synovial fluid) ... 1.33% and 2.9% in the total lymphocyte population and within the CD4+ subset, respectively (Panel b) Treg cells are efficiently removed (0.05% and 1.1% in the total lymphocyte population and within...
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Báo cáo y học: "Increased levels of circulating microparticles in primary Sjögren''''s syndrome, systemic lupus erythematosus and rheumatoid arthritis and relation with disease activity" pdf
... with glandular involvement only In addition, we found an inverse correlation between level of MPs and disease activity in RA and SLE Moreover, we found the level of MPs inversely correlated with ... LL, Kett DH, Schein DH, Ahn YS: Levels of endothelial and platelet microparticles and their interactions with leukocytes negatively correlate with organ dysfunction and predict mortality in severe ... biomarkers with disease activity Discussion In the present study, we investigated the plasma level of circulating MPs in patients with the AIDs pSS, SLE and RA and found a higher level of total and...
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Báo cáo y học: "Enhanced late-outgrowth circulating endothelial progenitor cell levels in rheumatoid arthritis and correlation with disease activity" doc
... patients and controls, (b) to assess correlations between EPC counts, CEC counts, and RA activity, and (c) to correlate EPC and CEC counts with levels of serum markers of synovitis or endothelial ... Associations of endothelial progenitor cell (EPC) levels in rheumatoid arthritis (RA) with disease activity Correlation between EPC counts and disease activity (a) and association of lower EPC levels in ... and 0.74, P = 0.003 and 0.0015, respectively) (Figure 2) Association between endothelial progenitor cell levels and disease activity In RA patients, EPC levels correlated with DAS-28 (r = 0.43,...
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Báo cáo y học: "Interferon-lambda1 induces peripheral blood mononuclear cell-derived chemokines secretion in patients with systemic lupus erythematosus: its correlation with disease activity" potx
... mRNA and protein levels between patients with active and those with inactive disease (P < 0.0001, P = 0.028) In the meantime, patients with active disease displayed higher IFN-l1 mRNA and serum ... compared with those with inactive disease (n = 15) as well as NC (b) Serum IFNl1 protein levels were significantly elevated in SLE patients with active disease compared with those with inactive disease ... in the serum of both SLE patients and healthy relatives, and it was associated with autoantibodies to RNA-binding proteins and double-stranded DNA [47] Levels of Type I IFN correlated with the...
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Báo cáo y học: " Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients" ppsx
... expressed as MFI (r = -0.80 with P = 0.003 and r = -0.63 with P = 0.038, respectively) PD-L2 PD-L1 PD-1 35 Percent of positive cells Discussion PD-1 and its ligands, PD-L1 and PD-L2, belong to the ... were measured on circulating CD4 and CD8 lymphocytes and monocytes in whole blood from healthy volunteers (n = 49) and septic shock patients at day to (n = 37) and at day to (n = 56) after the ... Sequential PD-1, PD-L1, and PD-L2 measurements on circulating CD4 lymphocytes and monocytes in patients with septic shock In 10 patients with septic shock, sequential blood samples were obtained...
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windows 8 secrets [electronic resource] do what you never thought possible with windows 8 and rt
... IE Metro and Desktop Meet and Don’t IE 10 and Default Browser Selection Summary Chapter 8: Get It Done with Windows 8’s Productivity Apps A Note About the Windows Productivity Apps and Your Microsoft ... an App Store and Why Does Windows Need One? First Rule of Windows Store: There Are Rules to Windows Store Launching Windows Store Using Windows Store Configuring Accounts and Preferences Summary ... Managing, and Playing Music Buying, Managing, and Playing Movies and TV Shows Summary Chapter 10: Xbox Games with Windows Games and the Metro Environment Finding and Acquiring Games for Windows Finding...
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Báo cáo y học: "Alterations in Arterial Blood Parameters in Patients with Liver Cirrhosis and Ascite" docx
... the pulmonary and hepatic disease in patients with severe liver cirrhosis and ascites Methodology Forty-nine (49) patients without any cardiopulmonary disease with liver cirrhosis and ascites (35 ... liver disease usually associated with portal hypertension and cirrhosis, is manifested by dyspnea, platypnea and orthopnea and nowadays is more widely diagnosed occurring in chronic liver disease ... of patients with chronic liver disease Arte- Int J Med Sci 2007, rial venous anastomoses and communications between the portal and arterial circulation as well as between bronchial and pulmonary...
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Báo cáo y học: "The association between disease activity and NT-proBNP in 238 patients with rheumatoid arthritis: a 10-year longitudinal study" pptx
... morbidity and mortality [9-11], and disease activity in RA correlates with mortality, CVD, and CHF [5,6] Hence, it is of interest to investigate how markers of inflammation and disease activity ... RA disease activity, medication used, and NT-proBNP levels (dependent variable) Materials and methods Patients We followed 238 patients with RA of less than years in duration longitudinally with ... marker of CVD in patients with RA Harney and colleagues [25] found that BNP levels were significantly higher in 26 patients with RA than in controls and correlated with end diastolic volume (r2...
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Báo cáo y học: "Increased production of soluble CTLA-4 in patients with spondylarthropathies correlates with disease activity" pps
... Similar to other autoimmune diseases [16,17], SpA are characterized by high serum sCTLA-4 levels with a significant and positive correlation with disease activity These high levels of circulating sCTLA-4 ... correlated with the clinical index of disease activity SLEDAI in one study [16], but not in a second [15] In systemic sclerosis, patients exhibited high levels of serum sCTLA-4 that correlated with disease ... Cytotoxic activity Bath Ankylosing Correlationand clinical index of disease T Lymphocyte Antigen- 4Spond(sCTLA-4) and clinical index of disease activity Bath Ankylosing Spondylitis Disease Activity...
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Báo cáo y học: "Markers of B-lymphocyte activation are elevated in patients with early rheumatoid arthritis and correlated with disease activity in the ESPOIR cohort" pdf
... months, and year) and were diagnosed as having RA or UA after year of follow-up Serum samples from 80 healthy blood donors were assessed for BAFF levels, and DNA samples from 90 healthy blood donors ... levels did not differ significantly between patients with early RA and those with undifferentiated early arthritis Serum BAFF level was not associated with total Ig, RF, or anti-CCP levels, disease ... (BLyS) isoforms in systemic lupus erythematosus: disease activity correlates better with blood leukocyte BLyS mRNA levels than with plasma BLyS protein levels Arthritis Res Ther 2006, 8:R6 27 Tan...
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Báo cáo y học: "Physical function, disease activity, and health-related quality-of-life outcomes after 3 years of adalimumab treatment in patients with ankylosing spondylitis" potx
... ATLAS study; 208 were randomized to receive adalimumab and 107 to receive placebo Most patients were white (95.6%) and male (74.9%) The average age was 42.2 years, and mean disease duration was ... function and HRQOL scores in patients with AS treated with adalimumab for up to three years BASDAI scores demonstrated improvement in AS disease activity from baseline to the end of the 24-week double-blind ... treatment in improving and sustaining patient-reported physical functioning and HRQOL Materials and methods Patients and study design The Adalimumab Trial Evaluating Long-Term Efficacy and Safety in AS...
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Báo cáo y học: "Increased plasma levels of the soluble Mer tyrosine kinase receptor in systemic lupus erythematosus relate to disease activity and nephritis" pot
... between sMer and disease activity in SLE sMer concentrations in SLE patients correlate to SLEDAI and are different between patients with or without nephritis and in patients with or without anti-DNA ... or IgA class and patients with rheumatoid factor had the same mean sMer and sTyro levels as those without rheumatoid factor This observation was Figure sMer and sTyro3 in patients with CLI, RA, ... glomerular filtration as the sMer levels did not correlate to the serum- creatinine levels The concentrations of sMer were also found to correlate to decreasing levels of C1q and the presence of antiDNA...
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