dlbcl de novo cd5 dlbcl and mantle cell lymphoma
Báo cáo khoa học: "A rare tumoral combination, synchronous lung adenocarcinoma and mantle cell lymphoma of the pleura" docx
... NSCLC, whereas Rubiales et al described the synchronous occurrence of a small -cell lung cancer and a Hodgkin lymphoma [9,10] Coexistence of adenocarcinoma and mantle cell lymphoma in other anatomical ... of mantle cell lymphoma: a report of cases associated with advanced colonic adenocarcinoma Mod Pathol 2001, 14:811-817 Padmanabhan V, Trainer TD: Synchronous adenocarcinomas and mantle cell lymphoma ... of adenocarcinoma located in the cecum and MCL involving the colon, the terminal ileum and the regional lymph nodes [13] Another case of synchronous existence of nodal mantle cell lymphoma and...
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Báo cáo khoa học: De novo synthesis, uptake and proteolytic processing of lipocalin-type prostaglandin D synthase, b-trace, in the kidneys pptx
... ribbon model of human L-PGDS, which is composed of nine b-strands (strand A, Gly40–Ala49; strand B, Cys65–Ala72; strand C, Gly76–Arg85; strand D, Gln88–Pro98; strand E, Ser104–Arg108; strand F, ... urine into the tubules and proteolytically degraded within lysosomes in the tubule cells Identification of L-PGDS of various sizes in monkey kidney and human urine We applied crude extracts of monkey ... strand G, Val128–Gly135; strand H, Phe143–Ser150; strand I, Ile177–Phe179) and a three-turn a-helix (Ala157–Ala169) The epitopes of MAb-5C11, MAb-10A5 and MAb-1B7 are shown in blue, orange and...
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Báo cáo khoa học: "Mantle cell lymphoma of the gastrointestinal tract presenting with multiple intussusceptions – case report and review of literature" docx
... a mantle cell lymphoma – positive for Cyclin D1, CD20, CD79a and CD5; negative for BCL16, CD23 and CD10 These immunomarkers are essential in distinguishing mantle cell from other types of lymphoma ... Ozdemirli M, et al.: Mantle cell lymphoma: clinicopathologic features and treatments Oncology 2003, 17:879-891 Michopoulus S, Petraki K, Matsouka C, et al.: Mantle- cell lymphoma (multiple lymphomatous ... Current Treatment Approaches for Mantle Cell Lymphoma J Clin Oncol 2005, 23:6409-6414 Lenz G, Dreyling M, Hiddeman W: Mantle Cell Lymphoma Established therapeutic options and future directions ANN Hematol...
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Báo cáo khoa học: " Peripheral blood complete remission after splenic irradiation in Mantle-Cell Lymphoma with 11q22-23 deletion and ATM inactivation" pot
... for Mantle- Cell Lymphoma J Clin Oncol 2005, 23:6409-6414 Andersen NS, Jensen MK, de Nully Brown P, Geisler CH: A Danish population-based analysis of 105 mantle cell lymphoma patients: incidences, ... 97:2773-2778 Camacho E, Hernandez L, Hernandez S, Tort F, Bellosillo B, Bea S, Bosch F, Montserrat E, Cardesa A, Fernandez PL, Campo E: ATM gene inactivation in mantle cell lymphoma mainly occurs ... enhancing anti-neoplastic cell- mediated effects [19] In this context, another radiation-induced cell killing mechanism to be considered is the so-called "bystander effect", well described in several...
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báo cáo khoa học: "Cytostatic and anti-angiogenic effects of temsirolimus in refractory mantle cell lymphoma" docx
... before and after temsirolimus showed the direct cytostatic effect of this mTOR inhibitor through cell cycle arrest, as demonstrated by down-regulation of cyclin D1 and Ki67 in lymphoma cells, and ... analysis of the lymph node biopsies before and six months after temsirolimus Quantitative studies showed a significant decrease of cyclin D1, cell proliferation, microvessel density and VEGF-A expression ... CHOP: Cyclophosphamide, Hydroxydaunorubicin, Vincristine, and Prednisone; RCHOP: Rituximab associated with CHOP; ICE: Ifosfamide, Carboplatin, and Etoposide; E-CHOP: Etoposide associated with...
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báo cáo khoa học: "Acute dyspnoea and single tracheal localisation of mantle cell lymphoma" ppsx
... Morvan, CHRU Brest, France 2Departement de Pneumologie, Hopital Cavale Blanche, Brest, France 3Laboratoire de Cytogénétique, Faculté de Médecine, Université de Bretagne Occidentale, Brest, France ... malignant lymphoma Nihon Kokyuki Gakkai Zasshi 2006, 44:197-201 Kuppusamy Gounder S, Sikder M, Srinivas S, Chang VT, Kasimis B: Asymptomatic mantle cell lymphoma in the trachea Leukemia Lymphoma ... diseases have different treatment regimens and prognoses Abbreviations MALT: Mucosal Associated Lymphoid Tissue; MCL: Mantle Cell Lymphoma Author details Institut de Cancéro-hématologie, Département...
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báo cáo khoa học: "Discordant lymphoma consisting of splenic mantle cell lymphoma and marginal zone lymphoma involving the bone marrow and peripheral blood: a case report" potx
... Coexistence of two discordant B -cell lymphomas in the skin and lymph node: report of a case with primary cutaneous follicle-center lymphoma and nodal mantle- cell lymphoma Br J Dermatol 2007, 157:629-631 ... cyclophosphamide; hydroxydaunorubicin (Adriamycin); Oncovin (vincristine) and prednisone; MCL: mantle cell lymphoma; MZL: marginal zone lymphoma Author details Department of Oncology, Transplants and New ... R, Jacob MC, Callanan M, Leroux D: Composite splenic marginal zone lymphoma and mantle cell lymphoma arising form independent B -cell clones Hum Pathol 2007, 38:660-667 Goteri G, Rupoli S, Stramazzotti...
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Báo cáo khoa học: "Non-polypoidal, synchronous mantle- cell lymphoma of small intestine: a rare case" potx
... synchronous lung adenocarcinoma and mantle cell lymphoma of the pleura World Journal of Surgical Oncology 2008, 6:137 Dogan A: Modern histological classification of low grade B -cell lymphomas Best ... Cyclophosphamide, Hydroxydaunorubicin, Oncovin, Prednisone or Prednisolone (CHOP), (2) Cyclophosphamide, Vincristine, and Prednisone (COP), and (3) Doxorubicin, Tteniposide, Cyclophosphamide, and Prednisolone ... CIgG() and negative for CD3 and CD20) Findings were significant for nonHodgkin lymphoma of B -cell origin with low malignant potential The tumoral origin is in the marginal cell zone demonstrating...
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Báo cáo khoa học: "MicroRNA-17-92 significantly enhances radioresistance in human mantle cell lymphoma cells" pot
... infect the established Z138c-Teton cells And then Z138c-TMP2 cell line was generated Cell culture The Z138c-miRNA-17-92 cell lines and Z138c-TMP2 cell lines were suspended in RPMI1640 supplemented ... irradiation, the cells were stained by Propidium iodide (PI) to detect the percent of cell death Immunoblotting and antibodies Cell lysates containing 20 μg of protein were resolved on sodium dodecyl-sulfate ... Gy compared between Z138c-TMP2 and Z138c-miRNA-17-92 cells The cell death of Z138c-TMP2 and Z138c-miRNA-17-92s cells after different doses of radiation The cell death ratio was evaluated using...
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Báo cáo y học: " Magnetic resonance imaging with pathological correlation in a case of mantle cell lymphoma of the parotid gland: a case report" ppsx
... clinical analysis of two indolent lymphoma entities - mantle cell lymphoma and marginal zone lymphoma (including the mucosaassociated lymphoid tissue and monocytoid B -cell subcategories): a Southwest ... lymphocytic lymphoma, centrocytic lymphoma, and mantle zone lymphoma [1] MCL has a characteristic morphological appearance consisting of small lymphoid cells with slightly irregular nuclear cells Its ... (vincristine) and prednisone/prednisolone; CLL: chronic lymphocytic leukemia; CT: computed tomography; Ig: immunoglobulin; MCL: mantle cell lymphoma; NHL: non-Hodgkin’s lymphoma; SLL: small cell lymphoma; ...
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Tài liệu Báo cáo Y học: Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA pdf
... cooperation of Dnmt3a and Dnmt1 in de novo methylation of DNA that can only be provided by in vitro experiments In this model Dnmt3a is targeted to a domain of the DNA that is subject to de novo methylation ... Dnmt3a and Dnmt3b in maintenance methylation also has been concluded from studies with cell lines which not express functional Dnmt1 [36] and, finally, a functional interdependence of the Dnmt3a and ... lethality Cell 69, 915–926 Okano, M., Bell, D.W., Haber, D.A & Li, E (1999) DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development Cell 99, 247–257...
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Báo cáo khoa học: Protein folding and disulfide bond formation in the eukaryotic cell pptx
... disul de oxidoreductase and related genes in the human genome, and understanding their specific functions and interrelationships is of considerable importance, given their value to industry and ... into gp120 and gp41 subunits Gp160 has 10 disul de bonds and folds very slowly in the ER, but needs to so in order to keep the amount of productively folded protein high The leader peptide of gp160 ... 177, 5430–5439 Land A, Zonneveld D & Braakman I (2003) Folding of HIV-1 envelope glycoprotein involves extensive isomerization of disul de bonds and conformationdependent leader peptide cleavage...
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Báo cáo y học: " De novo genome sequence assembly of a filamentous fungus using Sanger, 454 and Illumina sequence data" ppsx
... (see Materials and methods) in Materials and methods), and also identified small insertions or deletions (termed indels) The Velvet assembly generated from Illumina PE data alone yielded an N50 contig ... next-generation sequencing platforms In the work described here, we developed a hybrid approach that uses Forge for generating de novo draft genome sequences, and applied the approach to a filamentous ... data described above, alone or in combination, and devised a strategy for refining these assemblies Using Velvet (v.6.04 and v.7.31), we assessed assemblies generated from Illumina PE read data and...
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Báo cáo y học: "De novo acute megakaryoblastic leukemia with p210 BCR/ABL and t(1;16) translocation but not t(9;22) Ph chromosome" pdf
... are megakaryoblastic De novo AMKL in adulthood is rare, and carries very poor prognosis We here report a 45-year-old woman with de novo AMKL with BCR/ABL rearrangement and der(16)t(1;16)(q21;q23) ... translocation der(16)t(1;16)(q21;q23) Our case and the case reported by Kaloutsi et al [20] suggested that the FISH should be considered for detection of variant Philadelphia rearrangement in de novo ... chromosomes 22 and one yellow fusion signal on der(22)ins(22;9) To the best of our knowledge, this is the first report of de novo AMKL with rare variant of Philadelphia rearrangement and a novel...
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Báo cáo y học" Increased plasma membrane cholesterol in cystic fibrosis cells correlates with CFTR genotype and depends on de novo cholesterol synthesis" pdf
... mevastatin and resveratrol treatments, and cell and nasal tissue studies JB designed all electrochemical measurement studies and interpreted those data NS provided CFTR inhibitors and aided in designing ... Western Reserve University) Cells were cared for as previously described [11] IB3-1 cells, human epithelial with the delta F508 mutation (CF-phenotype), and S9 cells, IB3-1 cell stably transfected ... Previous work has demonstrated that cultured cell models of CF and nasal and tracheal epithelium from Cftr -/mice exhibit an increase in membrane cholesterol content [3,17] In order to determine if...
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Báo cáo y học: "Viral suppression of multiple escape mutants by de novo CD8+ T cell responses in a human immunodeficiency virus-1 Infected elite suppressor" ppt
... has developed de novo CTL responses to the variants which proliferate in response to antigen and suppress viral replication Further studies will be needed to determine whether the induction of de ... analysis, and drafted the manuscript RH provided patient samples RFS participated in study design and helped to draft the manuscript JNB conceived of the study, participated in its design and coordination, ... Unstimulated CD8 T cells from ES8 block infection by autologous and wild type virus (described in Figure 2a) as effectively as cells stimulated with autologous or wild type TW10 peptides CD4+ T cells from...
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New models and algorithm for de novo peptide sequencing of multi charge MS MS spectra
... (database search, de novo peptide sequencing etc) in order to reconstruct and identify the peptide which produced it Bakhtiar and Tse [2] provides a comprehensive introduction and overview to the ... the PRM ladder or prefix ladder and similarly the set of all suffixes forms the SRM ladder or suffix ladder of the peptide The prefix and suffix ladder forms the “full ladder” of the peptide Since each ... hybrid approach into peptide identification called tag-based peptide identification which first uses de novo sequencing to get short candidate peptide fragments called peptide tags, then use these...
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Dùng các mẫu để tùy biến Look and Feel của control
... chương trình, thay đổi mã XAML điều khiển để làm cho giao diện chúng thay đổi Khả phân tách code/design cho phép nhà phát triển thiết kế làm việc cách hữu hiệu ứng dụng Silverlight WPF 58 Silverlight ... mà có lẽ bạn biết “RoundButton” control template kích thước Button, nội dung hiển thị bên hard-coded (nó hiển thị “Push Me!”) Một tin tốt lành WPF Silverlight cho phép ta tùy biến cài đặt Chúng ... Silverlight Tutorial Lấy ví dụ, nhúng StackPanel với and bên trong: Điều làm Button trông giống Nhớ giữ nguyên hành vi tính cũ (khi nhấn...
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Tài liệu Báo cáo khoa học: Human enhancer of rudimentary is a molecular partner of PDIP46/SKAR, a protein interacting with DNA polymerase d and S6K1 and regulating cell growth docx
... (D) The peptide sequences of PDIP46 ⁄ SKAR identified by tandem mass spectrometry analysis and their position in isoform ⁄ a of PDIP46 ⁄ SKAR The asterisk indicates the peptide identified by manual ... Mahon GM, Trzaskos JM, Kay R, Der Campbell SL & CJ (1999) Dependence of Dbl and Dbs transformation on MEK and NF-jB activation Mol Cell Biol 19, 7759–7770 38 Breeden L & Nasmyth K (1985) Regulation ... Smyk et al Fig Comparison of the intracellular localization of ER and PDIP46 ⁄ SKAR fused to EGFP in the mammalian cells NIH ⁄ 3T3 cells (upper) and HeLa cells (lower) were transiently transfected...
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Tài liệu Báo cáo Y học: Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation ppt
... may both result from the activation of PKC-dependent and -independent pathways, while that evoked by PMA mainly proceeded through PKC/Ras/ Raf/MEK-dependent signals In addition, the finding that ... data show that cell exposure to NAMI-A time-dependently inhibited PCNA protein expression, as compared to untreated cells This effect was detectable after 24 h of cell treatment and reached the ... occurred in a dose-dependent fashion, reaching the maximal amplitude at 100 nM over a concentration range of 10–200 nM PMA (Fig 6B) Both NAMI-A and PD98059 dose-dependently counteracted and ultimately...
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