... treatment ingestion. After eating, an increase in heart rate occurred in all three treatment groups. The increase in heart rate does not coincide with the pharmacokinetics including blood ... caffeine user group in response to the product containing caffeine and p-synephrine. The results of this study in- dicate that ingestion of a product containing bitter orange extract, caffeine ... JP, Muller GJ. Coronary spasm and thrombosis in a bodybuilder using a nutritional supplement containing synephrine, octopamine, tyramine and caffeine. So African Med J. 2008; 98: 372-373. 22....
... pronouncing the last consonants, linking sounds and consonant clusters. Hence, students find hard to get information when they are listening. Finally,Finally, the material facilities, teaching ... following information. They fail in listening. The teachers should let students be in a good mood, in a listening environment. Students must be familiar with the topic that they are going ... culture relates to getting information in listening comprehension. Shortage of vocabulary barriers students from getting information. When listening they have to stop to think as they meet new...
... containing isoamyl nitrite as a main component.b) In the commercial products of an alkyl nitrite, small amounts of corresponding alkyl alco-hol, the decomposition product, are contained. Since ... nitrites; their boiling points are 98, 78 and 67 °C, respectively. Amyl nitrite is being widely used as a detoxicant for cyanide poisoning, because alkyl nitrites oxidize hemoglobin in erythrocytes ... solution (2 mg/mL), and kept airtightly in a refrigerator. A 5-µL volume of the above solution is placed using a microsyringe in a glass vial containing 1 mL of dimethyl sulfoxide (DMSO), capped...
... solution containing a large amount of the derivatization reagent has to be injected into GC/MS, resulting in the marked contamination of the ion source of an MS instrument. e lighting-up time ... mucosa and the skin results in its poisoning. In the murder terrorism with VX taking place in Osaka, Japan, 1994, VX was sprayed on the back of the neck of the victim using a syringe (the exposure ... stockpiling and use are being prohibited by the CWC international treaty as a chemical weapon together with those of sarin and soman. In addition, even material com-pounds for VX synthesis are being...
... conditions; an Autosystem XL (Perkin Elmer, Wellesley, MA, USA) and an FID were used. Column (oven) temperature: 50°C (2 min) →20 °C/min→200 °C(0.5 min)→5 °C/min→300 °C(5 min); injection temperature: ... 11-nor-9-carboxy-∆9-tetrahydrocannabinol in urine. J Anal Toxicol 8:255–259 13) Foltz RL, McGinnis KM, Chinn DM (1983) Quantitative measurement of ∆9-tetrahydrocannabinol and two ma-jor metabolites in physiological ... acid measured by GC/MS were 22 ng/mL in urine and 0.6 ng/g in the liver.Case 2: A paper factory worker was killed by being caught in a machine during working with it. e concentrations of ∆9-THC-11-oic...
... or dihydrocodeine is commonly included in over-the-counter drugs of antitussives.> Figure 3.1 shows metabolic pathways of morphine, heroin and codeine. Since morphine and codeine are nally ... containing poppy seeds [9]. It should be noted that an amount of codeine comparable to that of morphine are also included in the poppy seed- containing foods [10]. e half-life of heroin disappearance ... tetrahydropapavero-line in Parkinsonian patient undergoing L-3,4-dihydroxyphenylalanine therapy: a possible biosynthetic path-way of morphine from L-3,4-dihydroxyphenylalanine in humans. J Pharmacol...
... Table 5.1, clinical symptoms according to the concentrations of methemoglobin are pre-sented.⊡ Table 5.1Clinical symptoms appearing according to methemoglobin concentrationsMethemoglobin concentration ... Cyanosis in infants caused by nitrates in well water. JAMA 257:2788–2792 12) Fan AM, Steinberg VE (1996) Health implications of nitrate and nitrite in drinking water: an update on methe-moglobinemia ... containing nitrate salt can be considered. However, a form or a product con-taining nitrate ingested could not be speci ed in the present poisoning case.Notesa) When nitrite is present in blood,...
... determination of methemoglobin in blood containing carboxyhemoglobin. Forensic Sci Int 17:177–184 7) Sato K (1983) A method for determination of methemoglobin in blood containing carboxyhemoglobin. ... Microdetermination of oxyhemoglobin, methemoglobin and sulfhemoglobin in a single sample of blood. J Biol Chem 126:655–662 2) Leahy T, Smith R (1960) Notes on methemoglobin determination. Clin Chem ... 1732-amino-6-hydroxymethyl-8-hydroxyquinazoline 482aminomethyl phosphonic acid 5467-aminonitrazepam 195-aminoquinoline 499amitriptyline 271, 274, 276amniotic uid 12amobarbital 301, 303, 305, 308, 309amoxapine 271,...
... cocaine inhalation; the ratio was 10.6 on average for urine sampled 0–8 h a er the inhalation. e ratios increased according to the increase in time interval between the inhalation and samplings ... GC/MS analysis for cocaine and its main metabolites, such as ecgonine methyl ester ( EME) and benzoylecgonine ( BE), in urine and blood, are presented; a fatal cocaine poisoning case, which the ... cocaine in urine was as much as 8.5 % (> Table 4.1).According to human experiments, the urinary ratio of BE to cocaine was reported to be 5.9 on average for urine sampled 0–1 h a er cocaine...
... Figure 5.2223 In two autopsy cases of pentazocine poisoning, its concentrations were 9.2 and 3.3 µg/mL in blood, 43 and 34 µg/g in the liver, and not detectable and 4.5 µg/mL in urine, respectively ... 285 plus 217 (pentazocine) were used at the retention times of 3–7 min and 7–8 min, respectively. The amount of pentazocineand IS spiked into 1 mL of blank whole blood or urine was equally 50 ng.⊡ ... being analyzed by GC [1–4], HPLC [5–7] and GC/MS [8]. In this chapter, a simple method for GC/MS analysis of pentazocine in human whole blood and urine is presented.Structures of pentazocine...
... methamphetamine. However, in recent years, it has been increasing markedly; 3,500 tablets of LSD were seized in 1996, while 53,043 tablets in 2000 (about 15-fold increase), arousing a serious concern ... obtained by oral administration of as small as 20–75 µg of LSD. e ab-sorption of LSD from the digestive tract is rapid and distinct visual hallucination takes place 45 min–1 h a er oral intake ... powerful hallucinogenic drugs of abuse. LSD was explosively abused in U.S.A. in the latter half of the 1960s. In Japan, the amount of seizure of LSD is much smaller than that of methamphetamine. However,...
... obtained from clandestine tablets, are shown in > Fig. 7.3. e MDAs produce EI mass spectra characterized by intense ions resulting from the α-cleavage of the amines and some less intense ... increased catecholamine (including serotonin) release and blockade of reuptake resulting in cardiac and central nervous system e ects [15]. e e ects of MDMA vary depend-ing on its doses, frequency ... drugs are being usually sold in tablet forms in black markets. e tablets are o en imprinted with various kinds of graphic designs and commercial logos, including the 3-diamond (“Mitsubishi”...
... Springer-Verlag Berlin Heidelberg 2005II.3.1 Phenothiazines by Akira Ishii and Yoshinao KatsumataIntroductionPhenothiazine drugs, including chlorpromazine and levomepromazine, have been being ... Poisoning due to psychotropic agents. Adverse Drug React Acute Poisoning Rev 4:83–126 3) Geraut A, Kintz P, Traqui A et al. (1994) Toxicological findings in a fatality involving chlorpromazine. ... (1 min) →15 °C/mine →290 °C (10 min); injection temperature: 270 °C; interface temperature; 270 °C; carrier gas: He; its ow rate: about 1.5 mL/min; injection: splitless mode for 1 min followed...
... IgarashiIntroductionButyrophenone drugs including haloperidol are being widely used in the eld of psychiatry. e acute butyrophenone poisoning incidents sometimes take place; in such cases, ... solution, because it increases extraction e ciency due to its salting-out e ect.c) ere is a report using a haloperidol analog as IS, in which chlorine is substituted for the uorine; but this ... temperature: 100 °C (1 min) → 30 °C/min →270 °C (30 s) → 5 °C/min → 290 °C (5 min); injection temperature: 260 °C; separator tempera-ture: 280 °C; carrier gas: He; its ow rate: 1.5 mL/min; MS ionization...