differential diagnosis of multiple sclerosis and acquired central nervous system demyelinating disorders in children and adolescents
Báo cáo y học: "Ischemia as a possible effect of increased intraabdominal pressure on central nervous system cytokines, lactate and perfusion pressures" ppsx
... irrespective of the level of IAH Key messages • Intra-abdominal hypertension led to increases of ICP and ISP • Increased ICP and ISP resulted in decreases of CPP and SPP, respectively Marinis et ... marked in bold IAP, intra-abdominal pressure Cytokines (Table 1) Interleukin Lactate (Table 1) Abdominal insufflation to IAP 20 mmHg (T2) resulted in a statistically significant increase of IL-6 in ... concentration of N O and isoflurane was monitored continuously throughout the study in order to ensure that depth of anaesthesia was maintained and boluses of 25 to 50 μg fentanyl and mg midazolam...
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Báo cáo y học: "Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection" ppt
... cytokines including interleukin-4 and -10 counteract the production of neopterin [21] The same is true for anti-inflammatory compounds including certain HMG-CoA reductase inhibitors (statins) and ... Neopterin Macrophage lineage Figure Induction of neopterin formation in brain cells Pro-inflammatory cytokines like interferon-γ (IFN-γ) induce expression of GTP-cyclohydrolase I in various brain ... morbidity and mortality of HIV infection, including those involving the CNS and the previously most common of these, ADC/HIVE The study of CSF neopterin has contributed to our understanding of CNS...
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Báo cáo y học: "The impact of therapy for childhood acute lymphoblastic leukaemia on intelligence quotients; results of the risk-stratified randomized central nervous system treatment trial MRC UKALL XI" ppsx
... below The finding of similar outcomes in males and females is reassuring Initial reports of inferior outcomes in girls came from relatively small studies using combinations of methotrexate and cranial ... boys Again, changes in therapy protocols such as lack of co-administration of high-dose methotrexate and avoidance of radiotherapy in young patients may explain the lack of difference in IQ in our ... effects of treatment Here, we report the results of intelligence tests for patients and controls assessed at baseline and at and year time-points after initiation of treatment Results During the...
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Báo cáo hóa học: " Validity and reliability of the Spanish version of the DN4 (Douleur Neuropathique 4 questions) questionnaire for differential diagnosis of pain syndromes associated to a neuropathic or somatic component" docx
... Cutoff point A score > points in the sum of the 10 items of the DN4 questionnaire resulted in the best discriminant cut-off point for the sample after excluding patients with mixed pain and central ... 100% 0% > 10 Cutoff point A score > points in the sum of the 10 items of the DN4 questionnaire resulted in the best discriminant cut-off point for the overall sample Cut-off point in the DN4 questionnaire ... analysis of the properties of the questionnaire according to pain intensity revealed significantly lower sensitivity and specificity in patients with mild pain intensity The influence of pain intensity...
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báo cáo hóa học:" Validity and reliability of the Spanish version of the DN4 (Douleur Neuropathique 4 questions) questionnaire for differential diagnosis of pain syndromes associated to a neuropathic or somatic component" pdf
... Cutoff point A score > points in the sum of the 10 items of the DN4 questionnaire resulted in the best discriminant cut-off point for the sample after excluding patients with mixed pain and central ... 100% 0% > 10 Cutoff point A score > points in the sum of the 10 items of the DN4 questionnaire resulted in the best discriminant cut-off point for the overall sample Cut-off point in the DN4 questionnaire ... analysis of the properties of the questionnaire according to pain intensity revealed significantly lower sensitivity and specificity in patients with mild pain intensity The influence of pain intensity...
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Báo cáo y học: "ncreased serum HO-1 in hemophagocytic syndrome and adult-onset Still''''s disease: use in the differential diagnosis of hyperferritinemia" docx
... vein thrombus, central nervous system involvement, arterial occlusion, or gastrointestinal lesions in addition to positive CRP, indicating active disease; the other 10 were regarded as having inactive ... µg of total RNA, 200 nmol/l of probe, and 800 nmol/l of primers were incubated in 25 µl at 50°C for 2min and 95°C for 10min, followed by 40 cycles of 95°C for 15s and 60°C for The amounts of ... underlying diseases were systemic lupus erythematosus (SLE) in two; hematological malignancy, including non-Hodgkin's lymphoma, multiple myeloma, and acute myeloid leukemia, in three; and ASD and...
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Báo cáo y học: "Advances in Molecular Diagnosis of HBV Infection and Drug Resistance"
... two include the substitution of methionine (M) by the amino acids isoleucine (I) or valine (V) in the YMDD motif (C domain) at position rtM204V/I In the majority of cases, these mutations in the ... of lamivudine resistance including determination of ALT values, and especially HBV DNA (viral load) assays are routinely used in the clinic A comparison of these methods is presented in Table ... its role as a ‘baseline’ indicator of HBV infectivity, the measurement of viral load is an indispensable means for monitoring and confirming resistance to lamivudine therapy Indeed, resistance...
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Tài liệu Báo cáo khoa học: Differential effects of Mxi1-SRa and Mxi1-SRb in Myc antagonism ppt
... transcript in the adult intestine and in the developing embryo, whereas Mxi1-SRb transcripts predominate in the adult liver and kidney [12] In our initial description of Mxi1-SRa and its comparison ... The finding of these differential functions is in line with the dogma that the proteome gains functional complexity by encoding multiple isoforms of a given protein, with these isoforms having shared ... generated by introducing the WR cDNA containing the full 5¢-UTR in pcDNA3.1 The coding region of Mxi1-SRa and Mxi1-SRb were subcloned by PCR in a vector containing an amino terminal flag tag The...
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Cancer of the Brain and Other Central Nervous System doc
... Cancer of the Brain and Nervous System Histologic Type of Tumor Classification NOS, C716 - Cerebellum, NOS, C717 - Brain Stem, C718 - Overlapping lesion of brain and C719 - Brain, NOS; SPINE: C701 ... CNS and Miscellaneous Intracranial and Intraspinal Neoplasms In: Ries LAG, Smith MA, Gurney JG, Linet M, Tamra T, Young JL, Bunin GR (eds) Cancer Incidence and Survival among Children and Adolescents: ... Other Central Nervous System National Cancer Institute 205 SEER Survival Monograph Chapter 25 Cancer of the Brain and Nervous System Table 25.3: Cancer of the Brain: Race, Sex, Age (20+), Grade and...
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Báo cáo khoa học: Differential binding of human immunoagents and Herceptin to the ErbB2 receptor ppt
... ratio, indicate a binding stoichiometry of : for ERB-hRNase and Erbicin and of 0.5 : for ERB-hcAb and Herceptin, i.e each identical antigen binding site binds one molecule of ErbB2-ECD The binding ... growth inhibition (%) C 40 Fig Effects of soluble ErbB2-ECD on the binding and cytotoxicity of ERB-hcAb and Herceptin Binding curves of ERB-hcAb (A) and Herceptin (B) to SKBR3 cells obtained by ... single set of identical independent binding sites, using the Bindwork software supplied with the instrument, which provided the stoichiometry of binding (n ligand : protein), the change in enthalpy...
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Báo cáo khoa học: Differential binding of factor XII and activated factor XII to soluble and immobilized fibronectin – localization of the Hep-1/Fib-1 binding site for activated factor XII pdf
... for the interaction of FN with fibrinogen and fibrin [27] Hence, fibrinogen and fibrin inhibited the binding of FXIIa The binding of fibrinogen and fibrin has been mapped to type I modules of 5168 ... inhibition of the binding of FXIIa to FN by sulfatides and the surface-binding peptide of FXII strongly indicates that the binding does not involve the surfacebinding region in FXIIa [18] The lack of inhibition ... protein composed of modular subunits generating different domains [8], which harbor binding sites for glycosaminoglycans, collagen or gelatine, fibrin, and integrin receptors Some of these binding...
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báo cáo hóa học: " The burden of multiple sclerosis: A community health survey" pot
... Cost of multiple sclerosis by level of disability: a review of literature Mult Scler 2005, 11:232-239 Burden of illness of multiple sclerosis: Part I: Cost of illness The Canadian Burden of Illness ... status and quality of life of people with multiple sclerosis Disabil Rehabil 2001, 23:516-521 Minden SL, Frankel D, Hadden LS, Srinath KP, Perloff JN: Disability in elderly people with multiple sclerosis: ... J, Gonzalez JM, Rivera-Navarro J: Quality of life and its assessment in multiple sclerosis: integrating physical and psychological components of wellbeing Lancet Neurol 2005, 4:556-566 Patwardhan...
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báo cáo hóa học: " Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE" pptx
... restricted areas of the spinal cord displaying focal inflammation and demyelination (Fig 2E) Quantification of CCR1, CCR2 and CCR5 mRNAexpressing cells in relation to the stage of demyelinating activity ... expressed within inflammatory brain lesions in MS [18,39-41], and CCL3 has been demonstrated in cerebrospinal fluid of MS patients with relapsing-remitting disease course [42] In Interestingly and consistent ... Weiner HL, Hancock WW: CCR5(+) and CXCR(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions Proc Natl Acad Sci USA...
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báo cáo hóa học: " Oral administration of the KATP channel opener diazoxide ameliorates disease progression in a murine model of multiple sclerosis" ppt
... Diazoxide treatment diminishes area of demyelination and number of inflammatory lesions during the effector phase of EAE To examine EAE-associated demyelination and cell infiltration, histopatological ... decrease of GFAP intensity in cervical and thoracic region and when the spinal cord was globally analyzed in diazoxide treated animals (C) CD11b immunolabeling of spinal cord sections of vehicle- and ... lymphocytic infiltration into the spinal cord during EAE To determine whether diazoxide treatment affected T and B lymphocyte infiltration into the spinal cord of EAE mice, immunoflorescence using anti-CD3...
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báo cáo hóa học:" The burden of multiple sclerosis: A community health survey" potx
... Cost of multiple sclerosis by level of disability: a review of literature Mult Scler 2005, 11:232-239 Burden of illness of multiple sclerosis: Part I: Cost of illness The Canadian Burden of Illness ... status and quality of life of people with multiple sclerosis Disabil Rehabil 2001, 23:516-521 Minden SL, Frankel D, Hadden LS, Srinath KP, Perloff JN: Disability in elderly people with multiple sclerosis: ... J, Gonzalez JM, Rivera-Navarro J: Quality of life and its assessment in multiple sclerosis: integrating physical and psychological components of wellbeing Lancet Neurol 2005, 4:556-566 Patwardhan...
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Báo cáo nghiên cứu khoa học " ANTIGENIC DIAGNOSIS OF ROTAVIRUS, CORONAVIRUS AND ESCHERICHIA COLI K99 IN CALVES'''' FAECES " docx
... AND EFFICACY TESTING OF A VACCINE FOR THE CONTROL OF PRE-WEANING COLIBACILLOSIS IN VIETNAM Cu HP1, VA2 , Fahy Driesen SJ2, Moore K2, Vanderfeen A2, Do NT1, and Trott DJ3 1National Institute of ... Development Institute, 2Victorian Department of Primary Industries; 4School of Veterinary Science, The University of Queensland, Australia Introduction √ Quang Tri province is located on the coast of Central ... presence of: 1) Cocci; RV and 2) Crypto oocysts by standard faecal flotation and modified Ziehl-Neelsen staining of faecal smears, respectively; 3) RV; and 4) TGEV using an ELISA kit (Institut...
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Handbook of Multiple Sclerosis pdf
... Koch-Henriksen N Multiple sclerosis in Scandinavia and Finland Acta Neurol Scand 1995; (suppl 161):55–59 27 Sharpe G Multiple sclerosis in island populations: prevalence in the Bailiwicks of Guernsey and ... Encephalomyelitis and Multiple Sclerosis Berlin, Springer, 1983 14 Princeas JW, Kwon EE, Cho E-S, Sharer LR Continual breakdown and regeneration of myelin in progressive multiple sclerosis plaques In: Scheinberg ... disseminated sclerosis in this country (Scotland and the North of England) and in America Rev Neurol Psychiatry (Edinb) 1903; 1:12–17 Davenport CD Multiple sclerosis from the standpoint of geographic...
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Báo cáo khoa học: "Immunohistochemical study of constitutive neuronal and inducible nitric oxide synthase in the central nervous system of goat with natural listeriosis" potx
... of nNOS and iNOS in the nonneurological control brain Both nNOS and iNOS immunoreactivity was recognized in the brain of control goats No inflammatory cells were found in the brain sections of ... hematoxylin Magnification A and B, ×66 C and D, ×132 Immunohistochmical study of nitric oxide synthase in the central nervous system of goat Enhanced expression of nNOS and iNOS in L monocytogenes-infected ... nNOS and iNOS in neurons increased when bacterial encephalitis occurred This is the first study of NOS expression in the goat brain with listeriosis The involvement of iNOS in bovine and caprine...
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Báo cáo lâm nghiệp: " Differential effects of N, P and K on photosynthesis and partitioning of N in Pinus pinaster needles" pptx
... fertiliser explain only 10% of the increase of net photosynthesis within the canopy [31] Increases in leaf area and changes in biomass partitioning probably explain the bulk of the growth response ... P pinaster [6, 30] and Pinus strobus [43] A partial explanation may lie in a positive relationship between the concentration of P and amount of Rubisco, as observed in P pinaster [55] and in ... general and/ or lasting role in the response of growth to fertiliser addition The absence of differences in WUE (as indicated by δ13C) is almost certainly a function of the similarity of Amax...
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