diagnostic tools for the identification of myocardial fibrosis and changes in ventricular mechanics
Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc
... a role for a3 in the formation of native MII binding sites, but may reflect the Vc1.1 scarcity of these sites in the investigated brain tissues and/ or the formation of low affinity binding sites ... of participate in the formation of EpI-resistant a7 receptors, or an ACh-binding protein reveals the ligand-binding domain of that the functional properties of the nAChR are modified in nicotinic ... domain of each subunit contributes to the formation of the hydrophilic pore ACh binding protein has structural and functional homology to the extracellular ligand binding domain of the nAChR, and...
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Critical evaluation of diagnostic aids for the detection of oral cancer docx
... clinical examination and case-finding, even in primary care In experienced hands toluidine blue staining may be useful in the evaluation of oral lesions and as an adjunct in the surveillance of ... indicative of cancer The strengths of the study include its multicenter nature, enhancing generalizability of the results and the large sample size Another positive feature is the fact that the ... each other’s results The major weakness of the study, however, is that the gold standard (scalpel biopsy) was not performed in the majority of the Class II patients, a cardinal rule for the evaluation...
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Báo cáo khoa học: "A Unified Statistical Model for the Identification of English BaseNP" pptx
... Figure -7 summarize the outcomes of our statistical model on various size of the training data, x-coordinate denotes the size of the training set, where "1" indicates that the training set is from ... POS tagging can benefit from baseNP information Whether or not the baseNP information can improve the precision of POS tagging in our approach is determined by the identifier assignment of the baseNP ... encountered during baseNP identification, we calculate parameter (2) and (4) in the following way: In the experiments, the training and testing sets are derived from the 25 sections of Wall Street Journal...
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Báo cáo khoa học: "SOFTWARE TOOLS FOR THE ENVIRONMENT OF A COMPUTER AIDED TRANSLATION SYSTEM" pptx
... : the dispersal of information and the obscurity of the coding In ARIANE-78, the lexical data base may reside on much more 50 files, for a given pair of language Figure Screen Display during Interpretation ... a debugging tool for linguistic applications ; as a tool for converting the lexical base into a new form (for instance, loading it into a conventional data base) It is possible to imagine VISULEX ... one of the working files), update the dictionary, insert into the revision file a part of another file, make permutations or transpositions of Finally, we give an example of a VISULEX output The...
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Báo cáo khoa học: Affinity purification-mass spectrometry Powerful tools for the characterization of protein complexes ppt
... Analysis of protein complexes Within the scope of this review, we will focus on summarizing the current technical state of the art for the biochemical retrieval of associated proteins and protein complexes ... with protein folding, protein function, or the ability to interact with other proteins It is therefore advisable to create N-terminal and C-terminal fusions in parallel Despite some of these limitations, ... fusion protein has been widely used for the discovery and analysis of individual protein interactions and, to a lesser extent, protein complexes [20,21] In this approach, the protein of interest...
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Báo cáo khoa học: "Comparison of Diagnostic Methods for the Detection of Parasites in Fish" pdf
... Comparison of Diagnostic Methods for the Detection of Parasites in Fish and disadvantages, depending on the purpose and target of study For parasitological investigation, the classical methods (the ... placed in separate vials with PBS The content of selected separate organs (oesophagus, stomach, pyloric caeca and intestine) was scraped from the lumen and epithelial lining and inspected under the ... microscope Stretching of these metacercariae was done by hot formalin for two minutes Then, they were kept in Eppendorf tubes with neutral formalin (4%) Diagnosis of parasitic infections * Diagnosis...
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báo cáo khoa học: " Systems medicine and the integration of bioinformatic tools for the diagnosis of Alzheimer’s disease" doc
... encompass only informatics and statistics; for example, it includes the development of tools not only for storing and mining the data, but also modeling of the data in the context of disease pathophysiology ... medicine approach to AD Many tools are available for mining of heterogeneous biological data, although the focus of such tools and the challenges being addressed by them have largely been in the ... Genome Medicine 2010, 2:83 http://genomemedicine.com/content/2/11/83 Page of folding and thus formation and stabilization of protein secondary structure [36] The importance of understanding the structural...
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báo cáo khoa học: "Predictive genetic testing for the identification of high-risk groups: a simulation study on the impact of predictive ability" pot
... PPV of the test are strongly influenced by the relative magnitude of the size of the high-risk group and the disease risk in the population In addition, selection of high-risk groups with clinically ... percentage of individuals at high-risk to examine the impact of the frequency of the high-risk group on the relationship between the sensitivity, specificity, PPV and NPV Note that the frequency of the ... disease in the total population The pattern remained the same when we repeated the analyses for a disease risk of 10% (Additional file 3) Increasing the OR of all variants included in the genetic...
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Báo cáo y học: "A systematic approach for the identification of novel, serologically reactive recombinant Varicella-Zoster Virus (VZV) antigens" ppsx
... against VZV glycoprotein E (gE), since this viral protein has been shown to be the most abundant and immunogenic of all VZV gps eliciting both, the formation of neutralizing antibodies and the ... protein purification, microarray screen, line development and validation of VZV antigens in Line format AL, JH, HN and GJ participated in the design of the study AB conceived the study, and participated ... participated in its design and coordination and wrote the manuscript All authors read and approved the final manuscript Competing interests MGVP, TJ, AL, JH, HN, GJ and AB have non-financial competing interests...
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báo cáo khoa học: " EcoTILLING for the identification of allelic variants of melon eIF4E, a factor that controls virus susceptibility" pptx
... of the polymorphism within the locus studied and, therefore, restricts the necessity of sequencing the complete locus but only regions around the polymorphism In our case, these reasons together ... strains Significantly, the analysis of the Cz-eIF4E sequence showed polymorphisms in exon that result into non-conservative amino acid changes located at the amino-terminus of the protein; none of ... non-coding regions of the gene and are indicated by arrows Amplified regions are represented by black lines Sizes (bp) of PCR products are indicated below the lines Sizes (bp) of exons and introns...
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Báo cáo y học: " A statistical model for the identification of genes governing the incidence of cancer with age" pptx
... are integrated into a QTL mapping framework (reviewed in [16]) The basic principle of these models, called functional mapping, is to characterize the genetic effects of QTLs on the formation and ... algorithm Wang and Wu [21] derived a closed form for the EM algorithm to obtain the maximum likelihood estimates (MLEs) of the haplotype frequencies, and therefore the allele frequencies and linkage ... successfully used the simple algorithm to obtain the MLEs of parameters contained in Θ and Ψ Hypothesis Testing One of the most significant advantages of functional mapping is that it can ask and address...
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Báo cáo y học: "Do we use the appropriate controls for the identification of informative methylation markers for early cancer detection" doc
... cancer for in- depth discussion However, the points raised are likely to be valid for other types of tumors For all these, the addition of appropriate cancer-free control materials to the screening ... help in the identification of truly informative markers and would avoid missing DNA-methylation markers for early detection and risk assessment 10 11 12 13 14 References Jones PA, Baylin SB: The ... regions adjacent to the actual tumor as the sole control is probably insufficient for the identification and selection of methylation markers for early cancer detection, although these control samples...
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A proteomic approach for the identification of HCC serum biomarkers
... Gee and Dr Aung Myat Oo for providing, and trusting, me with the tissue and serum samples I am indebted to the big family in the Protein and Proteomics Centre In particular, I wish to thank Sandra, ... Siaw Ling, Qinsong, Justin, and Jason They taught me many things, engaged in thought-provoking discussions with me and at the same time, extended their friendship I am thankful for the former, and ... inflammation and liver injury, thereby inducing iterative rounds of liver regeneration In the face of chronic liver injury and sustained liver regeneration, liver fibrosis develops, progressing...
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Illustrated key for the identification of brachyuran zoeal stages (crustacea decapoda) in the plankton of peter the great bay (sea of japan)
... taxonomy and ecology of commensal crabs of family Pinnotheridae (Crustacea, Decapoda, Brachyura) of the Sea Okhotsk and northern part of the Japan Sea Proceedings of the Zoological Institute, Leningrad ... development of three species of crab in the subfamily Dorippinae Zoological Magazine 90, 21–32 Makarov R.R (1966) The larvae of Macrura, Anomura, and Brachyura of the west Kamchatka shelf and their ... belonging to families and 16 genera inhabit Peter the Great Bay (Russian waters of the Sea of Japan) We found larvae of only 16 species from families and 14 genera occurring in the plankton of Peter...
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Tài liệu Guidelines for the Management of Inflammatory Bowel Disease (IBD) in Children in the United Kingdom pdf
... IBD in the UK [12] Guidelines for the Management of Inflammatory Bowel Disease (IBD) in Children in the United Kingdom 2.3 Pathogenesis [13] The etiologies of both UC and CD remain unknown The ... presented in this way [7] 44% of patients with CD have no diarrhoea but the majority [72%] complain of abdominal pain Guidelines for the Management of Inflammatory Bowel Disease (IBD) in Children in the ... tests of faecal calprotectin and lactoferrin may become increasingly important both for screening and also monitoring disease activity in order to avoid more invasive investigations Abdominal...
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Tài liệu "Promoting healthy diets and physical activity: a European dimension for the prevention of overweight, obesity and chronic diseases" doc
... importance of achieving a balanced diet reducing the consumption of fats, free sugars and salt, of increasing the intake of fruits, vegetables, legumes, grains and nuts, and of performing moderate ... comparable set of indicators for health status, including in the area of dietary intake, physical activity and obesity IV.4.2 Under the health determinants strand, the Programme is supporting pan-European ... Transport and urban planning policies can ensure that walking, cycling and other forms of exercise are easy and safe, and address non-motorised modes of transportation The provision of safe cycling and...
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Tài liệu APICE: Common Mediterranean strategy and local practical Actions for the mitigation of Port, Industries and Cities Emissions pdf
... meeting of the APICE project will be held in Venice on 24th 26th January 2012 During the meeting a full day will be devoted to the discussion of the results of the intercomparison campaign held in ... prominent forums for discussing the latest scientific developments, applications and implications for policy and other users An important feature of the conference is that it brings together ... concerning the intensive monitoring campaign in each pilot area are available here: Air monitoring campaign in Venice.pdf Air monitoring campaign in Genoa.pdf Air monitoring campaign in Thessaloniki.pdf...
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Tài liệu Carrots, Sticks, and Promises: A Conceptual Framework for the Management of Public Health and Social Issue Behaviors docx
... the proffered choice In general, the presence of a reinforcer is incentive (marketing), whereas the withholding of a reinforcer or the onset of a punishment is coercive (backed by the force of law) ... if the target cannot discern the reward in doing so Dickson (1992) discusses the invisible hand of competition that constrains the self-interest of the firm and forces the firm to serve the interests ... consideration of the decline and reemergence of marketing philosophy in social marketing The Decline of Marketing Philosophy in Social Marketing , Social marketing emerged in the late 1960s and 1970s...
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Tài liệu Báo cáo khoa học: A novel coupled enzyme assay reveals an enzyme responsible for the deamination of a chemically unstable intermediate in the metabolic pathway of 4-amino-3-hydroxybenzoic acid inBordetellasp. strain 10d doc
... 2-Aminomuconic acid was synthesized by the methods of He and Spain [5] 2-Hydroxymuconic 6-semialdehyde was prepared by incubating catechol with resting cells of a mutant, strain Y-2, of the aniline-assimilating ... released ammonia The coupled enzyme assay revealed the mechanism of the deamination reaction and the subsequent metabolism, including the deamination step The product formed from 4-amino-3-hydroxybenzoic ... peak of the purified enzyme at 266 nm The typical protein absorption peak of 280 nm shifts to 265 nm if the protein contains a flavin-type cofactor [28] We failed to identify the cofactor of the...
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Ergonomic Principles and Checklists for the Selection of Office Furniture and Equipment doc
... Elevation of the shoulders; # Twisting of the trunk; # Forward reaching of the upper arm; # Abduction of the upper arm; # Ulnar deviation of the hand; and # Extension of the wrist The time for which ... on the ergonomic criteria being used in the selection process The aims of the criteria used in the checklists are to optimise the comfort and productivity of office workers and to minimise their ... (adjustable by fore -and- aft movement of the backrest) is the horizontal distance, measured from the front edge to the foremost point of the backrest on the centre line of the seat's width The minimum...
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