... deletion of the mnt gene, which encodes a member of the Mad family of antagonists of Myc, restores proliferation to c-myc deleted cells, suggesting that the balance of expression of members of the ... concentrations of oxygen (Soucek and Evan 2002) This is formally possible: however, several Myc-induced tumors are genomically unstable and show complex karyotypes and enhanced rates of double -strand breaks, ... Mediators of Mycinduced apoptosis include p53 and E2F1 and both have been implicated in Controlof Cell Proliferation and Growth by Myc Proteins 337 DNA damage responses (Hermeking and Eick 1994;...
... support of the Division of Viral Hepatitis and Division of Cancer Prevention andControlof the Centers for Disease Controland Prevention, the Department of Health and Human Services Office of Minority ... cirrhosis and cancer, the extent of ongoing risk behaviors, and the impact of HIV coinfection and other cofactors Assess the role of state and local disease registries in the delivery of prevention and ... not-for-profit coalition of public, private, and voluntary organizations; the Department of Health and Human Services Office of Minority Health; and VA sought guidance from the Institute of Medicine...
... support of the Division of Viral Hepatitis and Division of Cancer Prevention andControlof the Centers for Disease Controland Prevention, the Department of Health and Human Services Office of Minority ... Academy of Sciences and the Department of Health and Human Services (with support from the Centers for Disease Controland Prevention, the Office of Minority Health, and the Department of Veterans ... prevention andcontrolof hepatitis B and C / Heather M Colvin and Abigail E Mitchell, editors ; Committee on the Prevention andControlof Viral Hepatitis Infections, Board on Population Health and...
... Bethesda, Maryland Randall R Mayer Chief, Bureau of HIV, STD, and Hepatitis, Iowa Department of Public Health, Des Moines, Iowa Margaret L Brandeau Professor, Department of Management Science and Engineering, ... Committee on the Prevention andControlof Viral Hepatitis Infections R Palmer Beasley (Chair) Ashbel Smith Professor and Dean Emeritus, University of Texas, School of Public Health, Houston, ... hepatitis B and hepatitis C are important public health problems and that there are several barriers to prevention andcontrol efforts, such as a lack of knowledge and awareness about...
... focus on the ITO source and drain area and scans along the edge of the source and drain pads Laser pulses not scan across the channel of the transistor, or the exposed portion of the nanowire (b) ... low Therefore the trip voltage is mostly determined by the Vth of M2 and ro of M1 and M2, and could be smaller (1.5 V) than half of the supply voltage, V, as shown in Figure 3d To achieve enhanced ... voltage of an inverter consisting of two NMOS NWTs (a) Schematic for the circuit of depletion (left) and enhancement (right) mode inverters (b) SEM images of depletion mode inverters with pull-up and...
... 3.3.2 Standard deviation of slope (Sb) The standard deviation of slope is proportional to standard error of estimate and inversely proportional to the range and square root of the number of data ... measurements of some property One of the most common statistical terms employed is the standard deviation of a population of observation Standard deviation is the square root of the sum of squares of a ... following: Selection, handling and testing of QC standards Type and frequency of equipment checks and calibrations (for example, should the wavelength accuracy and the baseline noise of an HPLC UV detector...
... that of the controlled vehicle is not 27.5 SUSPENSIONS CONTROL Performance of passive suspensions (i.e suspensions made of springs and dampers) both in terms of comfort and handling is limited and, ... actual 452 27 CONTROLOF THE CHASSIS AND ‘BY WIRE’ SYSTEMS FIGURE 27.9 Working of an anti-lock system (ABS) (a) Time history of the speed of the vehicle andof the peripheral velocity of the wheel ... accompanied by controlof the gearbox and the clutch, which operate through the clutch pedal and the gear lever These controls are often automatic 27.1 Motor vehicle control 431 • Braking control is...
... relationship between phenotypical and genetic values) as suggested by Keiding and Olsen [15] Another reason may be the lack of knowledge of the genetic controlof traits in larch interspecific ... mostly missing and information on quantitative genetic controlof traits is rare As a result, breeders have currently no basis to efficiently select candidate parents of hybrids and hybrid vigour ... are part of the INRA breeding populations for European and Japanese larches Creation of mating plans by controlled crossing is usually laborious in larch because of capricious flowering and low...
... renewal of endo-membranes during this period might be associated with a seasonal inactivation of auxin receptor and carrier proteins Later on, the breaking of rest may occur when the conditions of ... regulation of cambial activity and xylogenesis during the annual cycle? Exogenous ABA can reduce wood production and radial enlargement of tracheids in conifers, particularly at the end of summer ... breaking of cambial dormancy (Little and Wareing, 1981Moreover, ABA content increases again in reactivating cambium, for example, in the trunk of Pinus contorta (Savidge and Wareing, 1984), and in...
... typological and dimensional assessment of patients with schizophrenia [1] and was conceived as an operationalized, change-sensitive instrument that offers balanced representation of positive andnegative ... Global ratings of Very Good, Good and Weak items, along with ratings of each of the five criteria for the items of the Negative Symptoms subscale were summarized above Criterion and were based ... 3.0) andNegative subscales (0.2 to 2.4) Examination of the item information function, probability density function and standard error of the PANSS subscales indicate that Positive and Negative...
... function of use, positive andnegative effects, and knowledge of safe use amongst young people aged 16–24 years Whilst not reported here, the study also explored aspects of marketing and supply, and ... within New Zealand and internationally – particularly with regard to use of the drugs by young people [4] The primary aims of this research were to investigate patterns and context of use of BZP-party ... and cards (distributed in party pill retail outlets, bars and clubs, tertiary education campuses, and a range of youth and health organisations) and advertisements placed in suitable online and...
... development of the protocol and to the collection and/ or analysis of data for this study All authors drafted and/ or critically read and revised the manuscript for important intellectual content and have ... additional evidence of the validity of an instrument, and it was measured using the effect size (ES) which gives a continuous parametric measure of the change between admission and followup and can be ... hostility and lack of cooperation, the most frequently reported categories were moderate and fairly severe at admission, and minimum and mild at discharge (Table 1) CGI-S scores At admission, 62.6% of...
... CARAT – Controlof Allergic Rhinitis and Asthma Test This is a translation to English of the of the preliminary version ofControlof Allergic Rhinitis and Asthma Test, the development of which ... rhinitis and asthma (ARA) are inflammatory diseases and are often associated The lack ofcontrolof these diseases is responsible for a significant loss in patient's quality of life and an important ... evaluation of healthrelated quality of life impairment The "Control of Allergic Rhinitis and Asthma Test" (CARAT) project [17] aims to develop a brief self-administered tool to quantify the degree of control...
... frame ossifies As the process of standing is repeated, neuromotor controlof the lower extremity and spinal muscles is coordinated with the postural reflexes of the head and neck through cerebellar ... medial surface of the occipital lobe in the walls of the calcarine sulcus [29] The visual field and pathway are important regulators of postural control Visual input for postural control helps ... is composed of the utricle, saccule, and semicircular canals Each of these organs is designed to detect specific types of motion The utricle and saccule detect linear accelerations of the head...
... Results and Discussion 81 4.3.1 Crystal Structures 81 4.3.2 Identification of Octahedral Rotations 82 4.3.3 Controlof Octahedral Rotations 87 4.3.4 Controlof Physical ... simple structure and robust properties of perovskite oxide ferroelectrics have attracted a lot of attention and stimulated development in both fundamental understanding on ferroelectric and practical ... Transport Properties and Electronic Structure 67 3.4 Summary 76 CHAPTER Controlof Octahedral Rotations and Physical Properties in SrRuO3 Films by Varying Oxygen Content and Film Thickness...
... addition of 50 mL of 10% citric acid, the mixture was extracted three times with 30 mL of EtOAc The combined organic layers were washed twice with 20 mL of 10% citric acid, 20 mL of water and 20 mL of ... addition of mL of water and slowly warmed to 23 °C over 1.5 h The reaction mixture was extracted three times with 10 mL of DCM The combined organic layers were washed with 10 mL of 5% NaHCO3, water and ... 4-43 OH and LiOH (1.0 mg, 0.021 mmol) were dissolved in mL O of a mixture of EtOH and water (2/1) under an inert atmosphere of argon The reaction mixture was stirred for 18 h at 23 °C and poured...
... mathematics and economic laws University of Applied Sciences, Isny/Allgaeu, Germany 1997 - 2001 Graduate of Pharmaceutical Chemistry (“Diplom-Ing.”) • Awarded patent for thesis work on the synthesisof ... University of Singapore, Singapore 2007 - 2011 Medicinal Chemistry Programme (PhD student under the supervision of Dr Martin Lear) • Affinity-Guided Isolation, Structure Elucidation and Total Synthesis ... Roche Diagnostics Department of Rare Reagents Hoechst AG, Frankfurt, Germany 1992 - 1995 Today part of the Sanofi-Aventis group Chemical Technician Apprenticeship and Qualification • Completed...