conservation of residual renal function in children reaching end stage renal disease
Báo cáo y học: "HIV DNA and Dementia in Treatment-Naïve HIV-1-Infected Individuals in Bangkok, Thailand"
... causes of cognitive impairment including gadolinium-enhanced brain MRI If clinically indicated, individuals underwent a lumbar puncture to exclude opportunistic brain infection, however of the ... underlying mechanisms to explain the continued prevalence of HAD in the era of HAART Since HIV DNA in M/MФ persists while individuals are on HAART and since monocytes likely play a critical role in ... subset showing low CD14-staining (0.49%) A limited number of individuals (HAD n=5; ND n=4) had analyses of PBMC subsets in which an adequate number of cells was available for separation Using flow...
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báo cáo hóa học:" Frequency of Drug-Resistant Variants of HIV-1 Coexistent With Wild-Type in Treatment-Naive Patients of India" pdf
... Journal of the International AIDS Society 2005, 7:68 increased up to 17%[4] In Africa and South Asia, including India, where most of the world's HIV-infected patients and most of those infected ... regions in the pol gene of HIV-1 clade C isolates from India[12] by extending their 3' ends Our study was designed to obtain preliminary data on the frequency of drug-resistant variants of HIV-1 in ... sequencing of the pol gene.[24-28] In Africa and South Asia (including India), where most of the world's HIV-infected patients and most of those infected with subtype C live, there is very little information...
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báo cáo hóa học:" Poor Efficacy and Tolerability of Stavudine, Didanosine, and Efavirenz-based Regimen in Treatment-Naive Patients in Senegal" potx
... detect a minimum 70% of patients reaching the end point (lower limit of the 95% confidence interval) Calculations were performed with the SPSS software package (SPSS Inc., Chicago, Illinois) Results ... predominance of bacterial sepsis In a comparison of patients treated in industrialized and poor countries, a large difference in mortality was noted during the 12 months following the initiation of ... zidovudine, lamivudine and indinavir for the initial treatment of HIV-1 infected individuals: selection of thymidine analog regimen therapy (START II) AIDS 2000, 14:1601-1610 Abstract Gerstoft J,...
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ANGIOPLASTY, VARIOUS TECHNIQUES AND CHALLENGES IN TREATMENT OF CONGENITAL AND ACQUIRED VASCULAR STENOSES doc
... the incidence of CHS and of ICH in the largest series published before 2010, including series of patients undergoing angioplasty of intracranial arteries In order to document the incidence of ... pressure and/or injection of thrombin Insertion of interventional sheaths in small arteries is associated with an increased risk of thrombosis Rapid heparinization after sheath insertion is usually ... levels during clamping of the ICA and increased oxygen-derived free radicals produced during the restoration of cerebral perfusion are involved in endothelial dysfunction and deterioration of autoregulatory...
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Novel dexamethasone-HPMA copolymer conjugate and its potential application in treatment of rheumatoid arthritis pdf
... and influx of inflammatory leukocytes is the hallmark of RA [4] The inflammatory synovial lining, especially the pannus tissue, resembles solid tumors in many ways, including the leaky nature of ... presented in Figure Almost 50% of the total endosteal surface in the calcaneus of AIA+saline group was undergoing active bone resorption, whereas only 3% of these surfaces were resorbing in the ... was significantly less in the joints from animals treated with one injection of P-Dex compared with four injections of free Dex In the bones of the ankle joint, the BMD of the P-Dex group was...
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báo cáo khoa học: "Patient Care Teams in treatment of diabetes and chronic heart failure in primary care: an observational networks study" pptx
... is worth mentioning that the variation in our outcome disease monitoring’ was mainly related to varying levels of creatinine testing, i.e., monitoring of kidney functioning Clinical research ... the number of involved health professionals and different disciplines A high number of involved health professionals could hinder coordination of care for an individual patient Multiple involved ... professional, where in reality more health professionals might be involved per discipline This could result in underestimation of the total number of involved health professionals From a clinical...
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báo cáo khoa học: "Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a cross-sectional European cohor" pot
... Department of Internal Medicine, University of Turin, Turin, 10060, Italy 8Department of Internal Medicine I, University of Bonn, Sigmund-Freud-Strasse 25, Bonn, 53127, Germany 9Liver Research Group, Institute ... overall The association testing of the nineteen SNPs chosen for follow up individual genotyping in the independent combined cohort validate the MPS association testing results for the IL28B region, ... Genotype cleaning was performed using PLINK [20] Accounting for obligate missingness, we discarded samples with a genotyping rate of below 89.47% (corresponding to less than 17/19 SNPs being assigned...
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Báo cáo y học: " Comparative efficacy and acceptability of methylphenidate and atomoxetine in treatment of attention deficit hyperactivity disorder in children and adolescents: a meta-analysis" pdf
... have been used in the treatment of ADHD The non-stimulant atomoxetine was introduced in the United States in 2002 It is a selective norepinephrine reuptake inhibitor Double blind studies have ... reports of suicidal ideation with atomoxetine and hepatic disorders have prompted warnings about the use of atomoxetine in these conditions [42] In cardiovascular disease too, atomoxetine must ... acceptability in treatment of ADHD in children and adolescents It also suggests that OROS methylphenidate is more effective and may be considered as first line treatment in treatment of ADHD in children...
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Báo cáo y học: " The study protocol of the Norwegian randomized controlled trial of electroconvulsive therapy in treatment resistant depression in bipolar disorder" doc
... and unintended sign (including an abnormal finding), symptom or disease temporally associated with the use of a medicinal (investigational) product, whether or not related to the medicinal (investigational) ... Impression of Improvement (PGI-I), YMRS [43], SF-36 [45], Multidimensional Scale of Independent Functioning- MSIF [46], proportion in each group attaining remission, time to remission, proportion in ... cognitive functioning Furthermore possible inflammation processes involved in bipolar depression will be investigated The design enables us to assess changes in a wider spectrum of cytokines as a function...
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Báo cáo y học: " Duloxetine in treatment of refractory chronic tennis elbow: Two case reports" ppt
... activity of descending inhibitory fibers passing from the brain to the spinal cord The neurotransmitters primarily involved in the descending pathways, that is, norepinephrine and serotonin, act ... synapse in the dorsal horn of the spinal cord Preliminary processing of pain information occurs here before transmission through ascending tracts to the thalamus and higher brain centers Pain information ... enhanced activity of norepinephrine and serotonin in descending fibers [13] Some antidepressants also inhibit sodium-channel function, which can dampen the activity of pain-relaying neurons [14]...
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Báo cáo khoa học: " Efficacy of consensus interferon in treatment of HbeAg-positive chronic hepatitis B: a multicentre, randomized controlled trial" docx
... Centre of West China Hospital of Sichuan University, the Department of Infectious Diseases of Second Affiliated Hospital of ChongQing Medical University and Centre of Infectious Diseases of First ... with 41.2% of patients in the IFN-alpha group at the end of treatment At the end of follow-up, 44.4% of patients in the CIFN group showed a decrease of HBV-DNA compared with 34.3% of the IFN-alpha ... 68 patients in the IFN-alpha group (p > 0.05) at the end of treatment During the follow-up period, complete response was seen in of 72 patients in the CIFN group and of 70 patients in the IFN-alpha...
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adjuncts in treatment of ards
... Vasodilators : Inhaled Nitric oxide (iNo) iv almitrine with/without iNo Aerosolized prostacyclins Inhibition of cyclic nucleotide phosphodiesterase Inhalation of Endothelin receptor antagonists 1 Inhaled ... forced back into the alveoli during next inspiration IN TGI Stream of fresh air (4 to L/min) insufflated thr – small cath or through small channel in wall of ET into lower trachea flushing Co2 laden ... PDE-2, PDE-3 : PDE-4 – Selectively degrade CAMP Inhalation of Endothelin receptor antagonist In ARDS – increased Endothelin levels ETA → Vasoconst ENDOTHELIN ETB → release No; PGI2 Non Selective ET...
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Báo cáo khoa học: "The staging of sepsis: understanding heterogeneity in treatment efficacy" ppt
... the response to intervention with strategies that target the innate host inflammatory response is dependent on the severity of the inciting insult, reflected in the mortality rate of the placebo ... proposes stratifying patients on the basis of measures of ‘predisposition’, the nature of the acute ‘insult’, the nature of the host ‘response’, and the baseline degree of ‘organ dysfunction’ [3] ... hand, intervention with anti-tumor necrosis factor therapy appears to be of benefit primarily in patients without Efficacy of drotrecogin alpha activated as a function of baseline severity of illness...
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Báo cáo y học: "Comparative effectiveness of manipulation, mobilisation and the Activator instrument in treatment of non-specific neck pain: a systematic review" pps
... severe pain there was a mean difference of 0.4 on the NRS in favour of manipulation, a difference in average pain of 0.23 in favour of manipulation and a difference of 0.92 on the NDI in favour of ... writing of the paper PM assessed quality of included papers, interpreted results and contributed to writing of the paper Appendix The Jadad instrument to measure the likelihood of bias in pain ... a mean difference of 0.06 on the NRS in favour of manipulation, a difference in average pain of -0.14 in favour of mobilisation and a difference of 1.03 on the NDI in favour of manipulation At...
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Báo cáo y học: "Differences between children and adolescents in treatment response to atomoxetine and the correlation between health-related quality of life and Attention Deficit/Hyperactivity Disorder core symptoms: Meta-analysis of five atomoxetine tria
... Atomoxetine in the management of children with ADHD: effects on quality of life and school functioning Clin Pediatr (Phila) 2006, 45(9):819-827 Page 14 of 15 23 Prasad S, Harpin V, Poole L, Zeitlin ... baseline, at endpoint, and for the change from baseline to endpoint, are shown by age subgroup using Pearson’s correlation coefficient and the corresponding 95% confidence interval All tests of ... Page of 15 Table CHIP-CE: Parent Report Form (PRF) Domain and Subdomain Definitions CHIP-CE domains and subdomains Definition Satisfaction Domain The parent’s assessment of the child’s sense of...
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compare the effect of mannitol and hypertonic saline (nacl3%) in treatment of acute elevated intracranial pressure in stroke patient
... threatening The etiology of raised ICP on stroke patient Intracranial hematoma: The formation and the size of the hematoma will define the severity of increasing ICP The clinical manifestation includes: ... Mannitol had effectiveness in 69 of 89 times of infusion (78%, confidence interval 67-86%); hypertonic saline had success in 88 over 95 times of infusion (93%, 95% confidence interval 85-97%) Chapter ... intracranial pressure in types of stroke, in level of elevated intracranial pressure The data of hemodynamics status: - Heart rate before and after osmotic therapy every 30 minutes coincide of...
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In vitro and in vivo study of ABT 869 in treatment acute myeloid leukemia (AML) alone or in combination with chemotherapy or HDAC inhibitors insight into molecular mechanism and biologic characterization
... Phosphoinositide 3-kinase Promyelocytic Leukemia Zinc Finger protein Phosphatase of Regenerating Liver Retinoblastoma Protein Red Fluorescence Protein RNA interference Receptor Tyrosine Kinase ... CCAAT/enhancer-binding protein α Chromatin Immunoprecipitation Combination Index Chronic Myelogenous Leukemia Colorectal Carcinomas C-terminal Src Kinase 4'-6-Diamidino-2-phenylindole Disease Free ... Shock Protein 90 Indirubin Derivative Interferon gamma-inducible gene 16 Immunohistochemistry Intraperitoneally Internal Tandem Duplication c-Jun N-terminal Kinase Kinase Insert Domain Receptor...
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Báo cáo y học: "Clinical review: Treatment of new-onset atrial fibrillation in medical intensive care patients – a clinical framework"
... understanding of AF in critically ill patients Competing interests The authors declare that they have no competing interests References Pinski SL: Atrial fibrillation in the surgical intensive ... is gained from studies in noncritically ill patients AF is probably the final common pathway of structural changes in combination with a trigger leading to abnormal activation patterns in the ... AF in patients undergoing CTS, and also reduced the hospital LOS and the ICU LOS [49-55] There is no consensus, however, about the clinical relevance of this finding since data are conflicting...
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Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
... pointes Unlikely Risk of liver injury in conjunction with lipid-lowering agents; risk of bleeding complications in conjunction with antiplatelet agents, warfarin, niacin Induction of CYP3A4 increases ... modifications should include avoidance of refined carbohydrates, including sweetened drinks, increased intake of omega-3 fatty acid, and small amounts of protein with each meal [11] Behavioral interventions ... 2004, of portacaval shunting, thereby decreasing first pass metabolism; decrease in quantities and affinity of plasma proteins, thereby increasing free-drug levels; increase in volume of distribution...
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Báo cáo y học: "Ozone Therapy and Hyperbaric Oxygen Treatment in Lung Injury in Septic Rats"
... efficacy of OT in sepsis was tested in some experimental settings, the benefits of OT have not been clarified adequately [20-23] Introduction of new strategies for treatment of lung injury in sepsis ... therapy in induced endotoxemic shock II The effect of ozone therapy upon selected histochemical reactions in organs of rats in endotoxemic shock Inflammation 2007;30:69-86 22 Bette M, Nusing RM, ... cytokines; and USCN Life Science Inc., Wuhan, China for MPO) Histologic evaluation Lung tissues were fixed in formalin for 24 h, embedded in paraffin and cut into µm sections The slides were stained...
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