concentration due to holes and notches
Energy savings due to daylight and artificial lighting integration in office buildings in hot climate
... functional and environmental requirements, have special characteristics compared to other buildings They are required to provide better environmental quality to enhance occupants' productivity and performance, ... consuming a large proportion of the total energy to maintain lighting requirements and visual comfort As much as 20% of the total energy consumed by an office building goes to lighting [10] Therefore, ... practiced designs and operational characteristics as revealed from survey questionnaire on selected local design offices and interviews of building operators as well as relevant standards and logic judgment...
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Health Education to Villages: An integrated approach to reduce childhood mortality and morbidity due to diarrhoea and dehydration; Maharashtra, India 2005 – 2010 pptx
... toilets, increased advocacy and education will be necessary to convince people to use the toilets, to create separate male and female toilets in schools, and to promote proper practices of hand ... recognizing symptoms of dehydration and properly managing diarrhoea, and on promoting these practices to mothers It is usually diarrhoea which first brings babies into contact with doctors and the health ... bottle, with a label about how to recognize signs and degrees of dehydration, how to prepare home fluids for rehydration, and how to mix and prepare home-made and packaged ORS Additionally, they...
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Báo cáo y học: "Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus" pdf
... oriented towards the protein center and away from the ligand-binding pocket; and one Cγ atom in the side chain of the mutant residues and a second Cγ atom of the wild-type V36 point towards the ... inhibitors VX-950 (telaprevir) and SCH 503034 (boceprevir) as well as of the co-crystallized protease ligands CPX and SCH 446211 The P1 to P4 and P'1 to P'2 groups are numbered according to the ... analysis and ligand docking CH performed rotamer analysis and ligand docking GM and AS performed analysis of residue interaction networks CS conceived experiments MA, SZ and TL conceived and designed...
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Analysis and compensation of log_domain filter deviations due to transistor nonidealities
... Chapter 1: Introduction LOG operator EXP opemtor Figure 1-4: Signal companding by LOG and E X operators represent the log-domain inputs and output, respectively Due to the LOG-linear-EXP format ... (a) a dissipative inductor and (b) a dissipative capacitor 61 4-2 Nonideal models for (a) an inductor and (b) a capacitor It shows both the component tolerance and the parasitic dissipation ... happens to be the corner-stone of the logdomain filtering technique It is the key eiement for converting linear signals into their compressed form for signal processing, and expanding them to restore...
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Children’s Health Deficits due to Diarrhoea: Effects of Water Supply and Sanitation Systems in Slums with Different Water Logging Conditions
... Short-term and Heavy rainy, SDG: Short-term and Drainage, LSD: Long-term and Stagnant, LHT: Long-term and Heavy rainy, LMK: Long-term and Monsoon flood, PDL: Persistent and Drainage, PHS: Persistent and ... correlation between DALYs lost due to diarrhoea and some factors relevant to hygiene practices, including using overhead hanging latrines, not washing hands before eating and after defecation, as well ... child succumbed to the illness The information was reported to investigators at the follow-up two weeks later The 2-week interval was chosen because diseases and symptoms assessed and reported by...
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The NCI Strategic Plan for Leading the Nation To Eliminate the Suffering and Death Due to Cancer pdf
... expanding access to data, investigating behavioral and sociocultural influences on cancer outcomes and access to care, and better understanding how to disseminate the results of research and ... nutritional approaches, and training and education for research and health professionals We will support and conduct studies to increase our understanding of and ability to measure the environmental, ... dietary and physical activity patterns, and other lifestyle factors to further understand how they contribute to cancer prevention as well as to carcinogenesis > Integrate preclinical and clinical...
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Báo cáo hóa học: " Effective harvesting, detection, and conversion of IR radiation due to quantum dots with built-in charge" docx
... performance of IR photodetectors and solar cells These improvements are due to effective harvesting of IR radiation via intra-band QD transitions and transitions from QDs to the conducting states ... and B52) and with inter-dot doping (devices B45 and B53) In devices B44 and B52 (Figure 1a), the dopant sheet concentration was 2.7 × 1011 cm-2 and 5.4 × 1011 cm-2, respectively Devices B45 and ... one, two, and three spatial dimensions [13] This simulation tool self-consistently solves Schrödinger, Poisson, and current equations for electrons and holes The conduction and valence bands of...
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Báo cáo hóa học: " Phytocontact dermatitis due to Ranunculus arvensis mimicking burn injury: report of three cases and literature review" pptx
... dressing and topical antibiotic weeks 47 F 25 NA Right knee C falcatus Wet dressing and topical mometasone cream 10 days 10 45 F Overnight days Abdomen, right leg R damascenus Wet dressing and topical ... Alli N: Phytocontact dermatitis due to Ranunculus illyricus: two cases J Eur Acad Dermatol Venereol 2006, 20(10):1372-3 Metin A, Calka O, Akdeniz N, Behçet L: Phytodermatitis from Ceratocephalus ... illyricus Wet dressing and topical antibiotics days 58 F days days Left knee R illyricus Topical antibacterial cream A few days 54 F days days Right knee R illyricus Wet dressing and topical antibiotic...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 1) pptx
... or more chronic, and they may vary from mild to very severe The site of hemolysis may be predominantly intravascular or extravascular With respect to mechanisms, HAs may be due to intracorpuscular ... correlation between hereditary causes and intracorpuscular defects, because such defects are due to inherited mutations; the one exception is PNH, because the defect is due to an acquired somatic mutation ... mild hereditary spherocytosis or with cold agglutinin disease may be diagnosed after years This is due in large measure to the remarkable ability of the body to adapt to anemia when it is slowly...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 2) docx
... Increased (up to 10X normal with intravascular hemolysis) Haptoglobin Reduced to absent Note: MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; LDH, lactate dehydrogenase The laboratory ... lactate dehydrogenase (LDH), increased aspartate transaminase, and reduced haptoglobin Urobilinogen will be increased in both urine and stool If hemolysis is mainly intravascular, the telltale sign ... about mM) goes hand in hand with the gradual loss of cellular organelles and of biosynthetic abilities In the end the erythroid cell undergoes a process that has features of apoptosis, including...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 3) pptx
... Chronic iron overload will cause secondary hemochromatosis; this will cause damage, particularly to the liver, eventually leading to cirrhosis, and to the heart muscle, eventually causing heart failure ... components in the red cell: (1) hemoglobin, (2) the membrane-cytoskeleton complex, and (3) the metabolic machinery necessary to keep (1) and (2) in working order Here we will discuss diseases of the ... pathophysiologic process common to all HAs is an increased red cell turnover The gold standard for proving that the life span of red cells is reduced (compared to the normal value of about 120...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 5) ppt
... a dimer of α-spectrin and β-spectrin The membrane is physically linked to the cytoskeleton by a third set of proteins (including ankyrin and the so-called band 4.1 and band 4.2), which thus connect ... glycosylated, and they carry antigenic determinants that correspond to blood groups Underneath the membrane, and tangential to it, is a network of other proteins that make up the cytoskeleton The main cytoskeletal ... of red cell membrane/cytoskeleton (For explanation see text.) (From N Young et al: Clinical Hematology Copyright Elsevier, 2006; with permission.) The membrane-cytoskeleton complex is indeed so...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 6) doc
... antigen nonspherocytic associated with hemolytic total loss of all anemia Rh antigens Note: HS, hereditary spherocytosis; HE, hereditary elliptocytosis ... Band HS (anion (dominant) channel) Mutations of this gene may account for ~25% of HS Southea st Polymorp Asian hic mutation ovalocytosis (deletion of (dominant) amino acids); clinically asymptomatic; ... Band 4.1 HE (dominant) Mutations of this gene account for about 5% of mostly HE, with prominent morphology but no hemolysis in heterozygotes; severe hemolysis in homozygotes EPB42 15q15-q21 Band...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 7) docx
... prophylaxis splenectomy is postsplenectomy is controversial HS patients often may require cholecystectomy It used to be considered mandatory to combine this procedure with splenectomy, but this may ... similar to that of HS However, an asymptomatic form, referred to as Southeast Asian ovalocytosis, has a frequency of up to 7% in certain populations, presumably as a result of malaria selection Stomatocytosis ... first approximation, has two important functions: (1) to provide energy in the form of ATP, and (2) to prevent oxidative damage to hemoglobin and to other proteins ...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 8) pdf
... neonatal jaundice; the jaundice persists and is usually associated with a very high reticulocytosis The anemia is of variable severity; sometimes it is so severe as to require regular blood transfusions; ... be delayed, and in some cases it is made in young adults—for instance, in a woman during her first pregnancy, when the anemia may get worse In part the delay in diagnosis is due to the fact that ... rare tosis rather than mutase (DPGM) Phosphog lycerate hemolysis Xq13 kinase Ver y rare CN S, NM May benefit (PGK) from splenectomy Pyruvate 1q21 kinase (PK) Rar May e (2) benefit from splenectomy...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 9) ppsx
... which, directly and via reduced glutathione (GSH), defends these cells against oxidative stress G6PD deficiency is a prime example of an HA due to interaction between an intracorpuscular and an extracorpuscular ... system, or both The diagnosis of HA is usually not difficult, thanks to the triad of normo-macrocytic anemia, reticulocytosis, and hyperbilirubinemia Enzymopathies should be considered in the differential ... decrease in G6PD activity in most tissues, this is less marked than in red cells, and it does not seem to produce symptoms Figure 101-4 Diagram of redox metabolism in the red cell G6P, glucose 6-phosphate;...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 10) pps
... to extremely severe, usually normocytic and normochromic, and due partly to intravascular hemolysis; hence, it is associated with hemoglobinemia, hemoglobinuria, and low or absent plasma haptoglobin ... starts with malaise, weakness, and abdominal or lumbar pain After an interval of several hours to 2–3 days, the patient develops jaundice and often dark urine, due to hemoglobinuria (Table 101-6) ... Mediterranean Sea, in the Middle East, and in India; G6PD A– in Africa and in Southern Europe; G6PD Vianchan and G6PD Mahidol in Southeast Asia; G6PD Canton in China; and G6PD Union worldwide The heterogeneity...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 11) doc
... hemoglobinuria exacerbations mediated (PNH) Flow Exacerba (C)- cytometry display destruction of CD59(–) CD59(–) to tions due to C a activation red through any red cell population pathway cells ... ranging blood smear from endothelial damage to hemangioma to leaky prosthetic heart valve March Abrupt hemoglobinuria Mechan Targete ical destruction d history taking Favism Acute Destruc G6PD Triggere ... normal Donath- triggered hemoglobinuria red cells viral infection (PCH) Landsteiner by antibody Septicemia Very acute Exotoxi Blood ns produced by cultures Other organisms may Clostridium be responsible...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 12) doc
... due to other causes In cases with CNSHA, if the anemia is not severe, regular folic acid supplements and regular hematologic surveillance will suffice It will be important to avoid exposure to ... normo-macrocytic, with reticulocytosis Bilirubin and LDH are increased Although hemolysis is, by definition, chronic in these patients, they are also vulnerable to acute oxidative damage, and therefore the ... consequent increased susceptibility to bacterial infections Laboratory Diagnosis The suspicion of G6PD deficiency can be confirmed by semiquantitative methods often referred to as screening tests, which...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 13) pptx
... complement regulatory proteins: membrane cofactor protein, factor H, and factor I It is thought that when complement is activated through the alternative pathway following damage to endothelial ... enables them to squeeze through capillaries narrower than themselves thousands of times in their lifetime, there are at least two situations in which they succumb to shear, if not to wear and tear; ... mild, and provided the supply of iron is adequate, it may be largely compensated If more than mild anemia develops, reintervention to correct regurgitation may be required Toxic Agents and Drugs...
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