... could haven 't been able to could could have been 10 could have phoned was able to could be couldn 't could have been can B haveto must/ haveto must/ havetomustn'tneedn 't/ don'thaveto 10 don'thave ... registering to announce to bring die to be to bring to changing Unit 9: Relative Clauses A l who/that who/that D 10 going closing to talk to change tohave lost to win to smoke read to stay watching ... able to be/could have been a star but she became a nurse instead 10 I could/can drive but I can 't ride a bike B: Choosethecorrectformofthe verb: must/ have to/ mustn' t/ needn 't/ don'thave to...
... could haven 't been able to could could have been 10 could have phoned was able to could be couldn 't could have been can B haveto must/ haveto must/ havetomustn'tneedn 't/ don'thaveto 10 don'thave ... registering to announce to bring die to be to bring to changing Unit 9: Relative Clauses A l who/that who/that D 10 going closing to talk to change tohave lost to win to smoke read to stay watching ... able to be/could have been a star but she became a nurse instead 10 I could/can drive but I can 't ride a bike B: Choosethecorrectformofthe verb: must/ have to/ mustn' t/ needn 't/ don'thave to...
... could haven 't been able to could could have been 10 could have phoned was able to could be couldn 't could have been can B haveto must/ haveto must/ havetomustn'tneedn 't/ don'thaveto 10 don'thave ... registering to announce to bring die to be to bring to changing Unit 9: Relative Clauses A l who/that who/that D 10 going closing to talk to change tohave lost to win to smoke read to stay watching ... able to be/could have been a star but she became a nurse instead 10 I could/can drive but I can 't ride a bike B: Choosethecorrectformofthe verb: must/ have to/ mustn' t/ needn 't/ don'thave to...
... looking at me as if she (know) me?knew 13 If I (be) a bird, I (not,want) to live in a snake.were / wouldn 't want 14 My brother managed to kill the snake just at the time when I (be) almost exhausted ... I wish out teacher would explain that lesson to us again tomrrow 11 I can hear his voice so clearly that it is as if he were hear but the fact is that he isn 't here 12 I have never met her before ... looking at me as if she knew me? 13 If I were a bird, I wouldn 't want to live in a snake 14 My brother managed to kill the snake just at the time when I were almost exhausted If he had beena little...
... greatest (satisfy) I’m not sure at all I really can t say with (certain) Travel is said tothe mind (broad) Maradona is one ofthe best football in the world (play) The town is situated on the river ... (ordinarily) It is such a evening Let’s go for a walk (love) I was to get your letter this morning (delight) The lesson was so that most of them went to sleep in the middle (interest) He soon put on when ... (wonder) I regret to you that they are unable to offer you employment (information) You are very from your brother (differ) Thetothe problem will be difficult to find (solve) Try to use your money...
... countryside in the area is ( charm) and most ofthe buildings there ear made from an( attract) of light stone that is particular tothe Cotswold’s In the summer, the Cotswold’s can get rather( ... Next month my grandparents are going to hold a party in ( celebrate) of their fiftieth wedding anniversary 60 They attach great ( important) tothe project 61 The ( decorate) touches ... natural resources is of great ( important) 117 That restaurant often attracts a lot of customers because of its( special) 118 These days it is ( possible) to open a newspaper without...
... yesterday A boy (knock) down by a car Then he (take) tothe nearest hospital 47 Most ofthe Earth’s surface (cover) by water 48 The first festival (hold) nearly eight hundred years ago 49 There’s ... football but now I dont 65 I (work) on a farm once and had to get up at every morning It was difficult at first as I (not get up) so early 66 Cuckoos (not build) nests They (use) the nests of ... when the phone (ring) It (stop) after a few rings 70 It (be) cold when we (leave) the house that day, and a light snow (fall) 71 I (walk) along the street when I suddenly (feel) something hit me...
... works - I to a great radio show on the way to work listening to listening have listening was listening - Tom's not here He's out _ his mother visit visited visiting is visiting - She _ ... has been have been - They _ on the project at the moment working be working is working are working - Do you still _ tothe tennis club? belongs are belong belonging belong - I never _ Tim anymore ... belong - I never _ Tim anymore see has see seen seeing - I _ football after work play to play playing am play 10 - We _ a lot of volunteer work are doing does ...
... LIMITATIONS OFTHE STUDY Due tothe limitation of time and the data collected, it is difficult for us to carry out perfectly although we have tried my best to avoid mistakes and limit shortcomings ... is to bring it tothe mind ofthe hearer without necessarily explicitly affirming it and without a strong commitment to its truth Recommend - To advise while presupposing that the future action ... can be accepted or rejected - To suggest something is to bring it tothe mind ofthe hearer without necessarily explicitly affirming it and without a strong commitment to its truth To advise while...
... different types 12 tochoosethe best and correct ones with cares to illustrate what we want to mention 3.5 2.2.5 Performative Verbs DATA ANALYSIS In this study, the collected data was analyzed on the ... in the Socialist Republic of Vietnam, the study has discussed opportunities to practice the syntactic and semantic features of saying verbs, pointed out the With the scope of this paper, we have ... documents in English and Table 2.1: Participants in a Verbal Process Vietnamese This reason makes the writer of this thesis to devote SAYER himself tothe study to find out the linguistic features of...
... growth factors by binding to pro -form- specific receptors [9–11] The pro-peptide ofthe related TGFb has been shown to retard the function ofthe mature protein by non-covalent association with the ... we attempted to obtain an insight into the function of proBMP-2 In order to obtain more information about the role ofthe pro -form, proBMP-2, i.e BMP-2 with the covalently attached pro-peptide, ... respect tothe mature part As neither the interaction with BMPR-IA nor with noggin was affected in quantitative terms, the pro-peptide moiety probably does not obstruct the key residues of BMP-2 that...
... tothe position ofthe active site lip and closure ofthe C-terminal end over the active site However, it is reasonable to expect these two events to be associated but the structural change that ... mechanism of regulation that generates the apparently attractive feature of an increase in both S0.5 and the sigmoidity ofthe saturation curve for dCTP in response tothe binding of dTTP tothe enzyme ... ordered C-terminal fold The dotted arrow points tothe region in the active site constituted by residues 120–125 that deviated in position between the dCTP ⁄ dUTP complexes and the dTTP complex The...
... point which is very close tothe galactic center It is than that he discovered that the arrow ofthe Sagittarius is placed there to point directly at the center ofthe Milky Way All the stars ... have a chance to transcend the old ways and to learn to live in peace and harmony with all the rest that exist in the Cosmos That process ofthe rebirth to half-etheric beings, according tothe ... for construction purposes Despite the fact that some ofthe scientists consider that they weight around 800 tons, the truth is that no one with 100% certainty can not say how much actually they...
... bound tothe C-terminus of p22phox tothe same extent; the binding was completely abolished by the P156Q substitution in p22phox, a mutation leading to defective interaction with the SH3 domains of ... Noxo1c to support Nox1 activity in unstimulated cells (Fig 3) may be due tothe fact that Noxo1c fails to fully localize tothe membrane The mechanism for the PMA-dependent membrane recruitment of ... barely located in the cytoplasm but Noxo1γ PMA: (–) (+) Noxo1γ phox Blot: anti-p22 activation [37] To test the possibility that cell detachment elicits activation of Nox1, we estimated superoxide...
... group of enzymes with the overall retention ofthe anomeric configuration ofthe substrate The conserved RDP motif in the vicinity ofthe active site ofthe enzyme is important for substrate recognition ... Enzymatic properties ofthe recombinant protein were identical to those ofthe native B longum KN29.1 b-fructofuranosidase, which suggests that the point mutation does not affect the enzymatic activity ... The quality ofthe final structures was assessed with procheck [81] The final refinement statistics are shown in Table The refined atomic coordinates and structure factors for the native b-fructofuranosidase...
... correlated strictly with phosphorylation ofthe CTD In support of this view, chemical kinase inhibitors that prevent phosphorylation-dependent transition from the initiation tothe elongation of transcription ... correlates with the interaction with 5542 Pol e, it is tempting to speculate that the interaction may be mediated by the CTD, in particular when phosphorylated at the repeated serine residues, although ... interaction does not depend on DNA replication Pol e is one ofthe three major replicases in the eukaryotic cell [22] Therefore, we tested the effect ofthe replicative state ofthe cell on the...
... 1.2 Table According tothe activity assay, the activity was retained above 95% (data not shown) and the recovery is 24% during the heat-treatment It implied that PKIb was a thermostable protein ... calculated According tothe above peak assignment, the relative contents of secondary structure in the human PKIb based upon the fitted spectrum are shown in Table The CD spectrum of human PKIb at ... 1.2% (Table 1) The purified PKIb showed a single band by SDS/PAGE (Fig 2) The assay of its activity demonstrated that the purified PKIb inhibited the catalytic subunit of cAPK with the specific activity...
... to that of proCPY It is interesting to note that protein stability is not necessarily dependent on the number of structural domains, but this issue may be extended tothe biological meaning of ... that the cleft ofthe active site will be located in the interface between the two structural domains of CPY and would be filled by the propeptide, thus uniting the two domains in a body, as if the ... deconvoluted into two peaks with Tm1 of 57.0 and Tm2 of 62.1 °C, as shown by the dashed lines of Fig 1B This strongly suggests that the thermal unfolding of CPY involves a multistate transition The temperature...
... changes in the surface ofthe protein because ofthe interactions ofthe cofactor with the protein This is further substantiated when one overlays the two forms ofthe protein (Fig 5B) The Plasmodium ... consistent with the LEM of protein unfolding [29] It is apparent from the solution denaturation studies that the holo formofthe protein has greater stability than the apo formThe differences in the ... unfolding thermodynamic parameters ofthe two forms are given in Tables 13 In the entire experimental regime, it is seen that the holo form presents better stability than the other form (Fig 4C) The...