... estimate ofthe cost-push shock We assume that these perceptions represent the best available estimates ofthe unobservable variables from the perspective ofthecentral bank Similarly, we use the ... level ofthe interest rate First, we assume that thecentral bank sticks to the original estimate ofthe intercept, never re-estimates and never considers the possibility of a structural shift The ... μf , for the case that thecentral bank sticks to the original estimate ofthe intercept, γ0 , in the money demand equation and never considers the possibility of a structural shift The lower...
... appearance of metasta- http://www.wjso.com/content/6/1/7 sis is a frequent complication of breast cancerThe lung is the second most common organ for metastasis of breast cancer after the bone ... east part ofthe country where hydatid disease is endemic Positive indirect hemaglutination test supported the diagnosis of pulmonary echinococcosis Chemotherapy for Stage IIIC breast cancer (Adriamycin, ... PET has been shown to have impact on the staging and management ofrecurrent or metastatic breast cancer in cases of suspicion and in a follow-up setting The current oncological situation can...
... for the conduct of these studies because of delays in registration The main value ofthe registry is rather to evaluate the completeness and representativeness ofthe case series 394 Theroleof ... established, by the method of data collection used and by the resources available to the registry However, the emphasis should be on the quality ofthe data collected rather than on the quantity ... available, the incidence date should be taken as the date of first diagnosis by a physician or the date ofthe first pathological report A special problem arises when 388 Theroleofcancer registries...
... in their models [19] To obtain more insight into theroleofthe fat breast tissue, we investigated the independent effects ofthe size of dense tissue and the size of non-dense tissue in the ... subtracting the dense area from the total breast size The size ofthe dense and non-dense areas in cm2, was determined by multiplying the number of pixels in the respective areas by the size of one ... breast cancer development [3,34] Also, it has often been hypothesized that the area ofthe dense tissue would reflect the effect of estrogens on the breast, because many determinants of mammographic...
... ovarian cancer cells [20]; however theroleof genistein in chemo-resistant ovarian cancer cells has not been investigated Therefore, the intent of this study was to evaluate the effect of genistein ... inhibition of NF-κB compared to the treatment of cells with any ofthe drugs alone (Figure 4) These results suggest that the pretreatment of cells with genistein sensitized ovarian cancer cells, ... several cancers, including ovarian cancer [4-7] Moreover, mutations may be one ofthe major factors contributing to the origin of ovarian cancer stem cells Emerging evidence suggests that ovarian cancer...
... plan The top ofthe treatment field was placed at the L4-5 junction, with the lateral borders 1-2 cm outside the bony pelvis, and the inferior margin at cm below the tumor A total dose of 41.4 ... cancers [2] The larger volume of blood supply to the liver in comparison with other organs and the tendency ofcancer cells to deposit and multiply in the liver after passing through the portal ... (stage III) These results suggest that pelvic RT may benefit all patients regardless ofthe status of their liver metastasis However, the number of patients who received resection ofthe primary...
... all but ofthe 11 subjects for the duration ofthe anesthetic This result suggestsa central mechanism as the mediator between the myofascial trigger points andlight sensitivity; however, the phenomenon ... PPT within minute ofthe injection The purpose ofthe control group was to assess the effect of systemic lidocaine on PPT versus the more specific trigger point infiltration in the symptomatic ... contrast, the increase in cervical range -of- motion observed in the symptomatic cohort following the injections suggests that the initial finding of reduced motion was either a result of peripherally...
... RW: The effect of additions of fluorine to the diet ofthe rat on the quality ofthe teeth 1925 Studies on experimental rickets XXI An experimental demonstration ofthe existence of a vitamin which ... deposition 1922 The effect of additions of fluorine to the diet ofthe rat on the quality ofthe teeth 1925 J Biol Chem 2002, 277:E8 Holick MF: Evolution and function of vitamin D Recent Results Cancer ... with the risk of colon cancer [109] For lung cancer, the picture is not clear at the present time While TaqI polymorphism ofthe VDR gene appears to be a risk factor for lung cancer Page of [110],...
... of these processes are hallmarks ofcancer and NF-κB has been hypothesised to have a role in tumorigenesis The aim ofthe current study was to investigate theroleof both NF-κB pathways in the ... Theroleof IKKalpha, IKKbeta and NF-kappaB in the progression of breast cancer Lindsay Bennett BSc(Hons), MSc Submitted in fulfillment ofthe requirements for the degree of PhD Institute of ... [2] The arrow has been added to indicate the introduction ofthe screening programme in 1988 18 Breast cancer has, however, one ofthe highest survival rates ofthe most common cancers in the...
... common mechanisms of action of these drugs are the inhibition ofthe rate limiting steps of Aβ generation i.e β- and/or γ- secretases processing of APP (Citron, 2010) Although the reasoning behind ... the neurons The research group detected the significant presence of H2S in the brain homogenate preparation of CBS-/- mice (Shibuya et al., 2009) Kimura further observed that 3-MST acts together ... MPP+, the active metabolite of MPTP They found that H2S inhibited the loss of MMP and the accumulation of intracellular ROS (Yin et al., 2009) Recently, Li et al (Xie et al., 2013) confirmed the...
... just another illustration ofthe complexity associated with cancer cells and tissues, where multiple factors act along with, or counter the action of one another in intersecting pathways The cancerous ... elevated in the presence of MUC1-C may enhance instead of retard EGFR signalling in these cells Another point of contention that requires further clarification pertains to the effect of Rab31 on ... 58], a member ofthe Rab11 subfamily that is highly expressed in the epithelial cells ofthe gastrointestinal tract, lungs and kidney, has in the past few years been implicated in cancers from...
... lines 84 IX LIST OF FIGURES Figure 1.1 Therapeutic targeting ofthe hallmarkers ofcancer Figure 1.1 Therapeutic targeting ofthe hallmarks ofcancer Figure 1.2 Anatomy ofthe normal female ... increasing the efflux of drugs out ofthe cell and thus decrease the level of drugs within the cells to inhibit the effects ofthe drugs (Dumontet and Sikic 1999) Docetaxel is the one ofthe substrates ... from the advances in cancer treatment and early detection of breast cancer 1.2.3 Breast cancer risk factors There are some proposed risk factors contributing to the development of breast cancer The...
... ELUCIDATING THEROLEOF AUTOPHAGY IN ZEBRAFISH MODELS OF LIVER CANCER SIM HUEY FEN, TINA (B.Sc.(Hons.)), NUS A THESIS SUBMITTED FOR THE DEGREE OF MASTER OF SCIENCE DEPARTMENT OF BIOLOGICAL ... between their genomes further allow the use ofthe zebrafish in the identification of gene functions of unknown genes in both zebrafish and humans (Barbazuk et al., 2000) In all, these attributes of ... are present in a gene-ofinterest Progeny identified to carry the desired mutations are then propagated to maintain the line to study the function ofthe gene -of- interest Furthermore, fluorescent...
... breast cancer metabolism in the study model Picture showing different lactate production in normal and cancer situation Schematic overview oftheroleof PrP in cancer metabolism in breast cancer ... accumulation ofthe latter This in turn causes irreversible damage to the neurons and reduces the availability of PrPC which may interfere with the presumed neuroprotective roleofthe protein, ... function of PrP While most studies are focused on theroleof PrP in neurodegenerative diseases, its function outside the nervous system remains unclear Some ofthe hypothesized functions of PrP...
... who are truthful and demonstrate regard for their own outcomes and those of others • Moderately Politicized Area – greater acceptance of behind the scenes tactics so long as the goals ofthe group are achieved ... Outline Roleof Power Rules for Using Power Roleof Power Power defined: • Ability or official capacity to exercise control; authority • Ability to influence or control others Sources of Power ... Find the Soft Spot Encourage others to open up • Gain disclosure of something private or personal about your counterpart • Expression of trust Identify true motivations and sources of objections...
... DC: The World Bank) Chernow, Ron, 1997, The Death ofthe Banker The Decline and the Fall ofthe Great Financial Dynasties The Triumph ofthe Small Investor (New York: Vintage Books, a Division of ... factoring the long-term market potential of borrowing firms in their risk analysis The higher their reputational capital, the stronger their incentive to lengthen the time horizon of their approach ... to further improve the bank’ risk position s and counterparties, on their side, might consider for them unnecessary to further assess the riskiness ofthe bank Finally, the inadequacy ofthe static...
... such professional colleagues on the world The Association has theroleof coordinating the activities ofthe members in order to protect the interests ofthe members and improve the position of Vietnam ... to the realization ofthe objectives and duties ofthe Association, may be invited to join the Association as Honorary members In general, this stipulation on the membership in the Statue ofthe ... under the supervision and management ofthe Department of Transport and Public Works of Ho Chi Minh City State-owned corporations under other central government ministries are also another type of...
... where the consequences of infection can be very severe, while the risk of living with one’s beloved cat is practically nill References Angulo FJ, Glaser CA, Juranek DD et al Caring for pets of immunocompromised ... with the human immunodeficiency virus Clin Infect Dis.1994;18:14-24 Han K, Shin DW, Lee TY, et al Seroprevalence of Toxoplasma gondii infection and risk factors associated with seropositivity of ... 94: 963-965 Grant S and Olsen CW Preventing zoonotic diseases in immunocompromised persons: theroleof physicians and veterinarians Emerg Infect Dis 1999; 5: 159-163 http://www.medsci.org ...
... and English at the expense ofthe other languages that exist in the country, the adult language program in Botswana maintains the hegemony and the gap between the poor and the rich, the major and ... improve the quality of life ofthe poor and rural people adult education programs should include as one of its components the observation and imitation ofthe artisans and other skilled persons in the ... for the betterment of their conditions It could mobilize the so called minorities to oppose their status and challenge the hegemony ofthe majority communities in Botswana 31 In most parts of the...
... sells the transaction to the acquire and is reimbursed the amount ofthe sales ticket by the acquirer (4) - The acquirer then summits the ticket to the issuer for payment, via the ICO interchange ... system 9 (5) - The issuer bills the cardholder (6) - Finally, the cardholder repays the issuer for the goods or services originally purchased from the merchant ICO are at the centre ofthe transaction ... maintaining the flow of funds and information between issuing and acquiring members The exchange of financial information is called clearing The exchange ofthe actual funds for the transaction and the...