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... other infected animals. A change in the NA amino sequence may allow a “back-door” to HA cleavage, leading to systemic infection. This mutant NA will bind to plasminogen a normal precursor in ... plasminogen is converted to plasmin, the active form, it functions as a protease to cleave HA which creates a systemic infection as well [1]. Taubenberger [1] reported that this transformation ... have to combat influenza is isolation and culling of infected fowls as demonstrated by the government of China, Vietnam, and Thailand. As human populations continue to increase and interactions...

Ngày tải lên: 02/11/2012, 11:12

Ngày tải lên: 27/12/2013, 20:26

... 4179– 4 186 . 19 Fan JQ, Ishii S, Asano N & Suzuki Y (1999) Acceler- ated transport and maturation of lysosomal alpha-galac- tosidase A in Fabry lymphoblasts by an enzyme inhibitor. Nat Med ... 103, 1 381 3–1 381 8. 29 Yu L, Ikeda K, Kato A, Adachi I, Godin G, Compain P, Martin O & Asano N (2006) alpha-1-C-octyl-1-de- oxynojirimycin as a pharmacological chaperone for Gaucher disease. ... report: improvement in cardiac function in the cardiac variant of Fabry’s disease with galactose-infusion therapy. N Engl J Med 345, 25–32. 18 Asano N, Ishii S, Kizu H, Ikeda K, Yasuda K, Kato A, Martin...

Ngày tải lên: 18/02/2014, 16:20

... ã That you want to help them ã To see you as the solution to their problem, and not be seen as your problem ã To be treated as mature adults, not as children ã That you will be patient ... belle loves and loses and loves again a slyly dashing war profiteer as she struggles to protect her family and beloved plantation. ã A pig raised by sheepdogs, learns to herd sheep with a little ... experiences and rationalize bad situations into good ones. You have a propensity towards narcotic addiction. Twisted Apart, The Inside, And Then The Cookie: You have a very curious nature. You take...

Ngày tải lên: 19/02/2014, 14:20

... L. lactis ald gene as follows. A PCR fragment was generated using primer CP-pyk (5Â-ACGACTAGTGGATCCATNNNNNAGTTTATTCTT GACANNNNNNNNNNNNNNTGRTATAATNNNNAA GTAATAAAATATTCGGAGGAATTTTGAAATGAATA AACGTGTAAAAATCG-3Â)(Nẳ ... enzymes: J l a las ịẳ 0:0123 93:9 a las ị1 e 7: 1a 3:2 las ị0:276, J glucose a las ịẳ 0:693 83 :3 a las ị1 e 6a 2:1 las ị33:2 (User dened), J lactate a las ịẳ0:919 129 a las ị1 e 6a 2:1 las ị75:2 ... (5Â-GGAAGGA TCCTTTGTCAATTAATGATCTTAAAAC-3Â) and pyk4 (5Â-CTAGTCTAGATGAGCTCCAGAAGCTTCC-3Â) were amplied. The PCR products were digested with XhoI ⁄ BamHI and BamHI ⁄ XbaI, respectively, and cloned...

Ngày tải lên: 19/02/2014, 17:20

... CGGAAACGCCTTAAGTCCAG GCCACAATCCAGTCATTCCA 83 MT 2A AATAAGCTTCCGACTCTAGCCGC GATAAGCTTGTGGAAGTCGCGT 259 CD237904 AGCTGGTGCAGGAGGAAGTA TCTCACTGGCCCTAAACTGG 92 AL707095 CCGAGAACCGAACTTACCAA CTGATAGGGGTTGGGTGATG ... (5Â -to3 Â) Size (bp) MDR1 GAAGAAGGGCCAGACGC CTCCTGGGACACGATGC 1 78 MRP1 CCTTCGCTGAGTTCCTGC CTGCGGTGCTGTTGTGG 246 BCRP ACATCAGCGGATACTACAGAG CACCATCATAAGGGTAAACAT 173 CA9 TTTGAATGGGCGAGTGATTG ACAGCAAAAAGGAGGCCAAA 1 38 BMP2 ... CTGATAGGGGTTGGGTGATG 1 28 AK095731 AGGAAGCACCCAGCAATACCA GCATTTCCATTTCCCTAAGCAC 109 DKK1 CACCTTGGATGGGTATTCCA CAACACAATCCTGAGGCACA 114 BC03 785 1 CACAGCTCCCATTCATTCCA TCCCTTTGCCTCCTGTTGTT 107 b-Actin TCCTCCCTGGAGAAGAGCTA...

Ngày tải lên: 06/03/2014, 22:21

... also operate in the present case. The heat-induced activation of kinases such as Akt has been shown to increase HSF1 activity. Enhanced Ras maturation by heat stress was associated with a heightened activation ... Suhan PJ (1 985 ) Morphological study of the mammalian stress response: characterization of changes in cytoplasmic organelles, cytoskeleton, and nucleoli, and appearance of intranuclear actin filaments in ... Sci USA 93, 387 0– 387 5. 12 Horvath I, Glatz A, Varvasovszki V, Torok Z, Pali T, Balogh G, Kovacs E, Nadasdi L, Benko S, Joo F et al. (19 98) Membrane physical state controls the signaling mechanism...

Ngày tải lên: 07/03/2014, 12:20

... those measures that are being used inthetarget areas as well as foreigncountries, such as Indonesia, China, Bangladesh, Germany, Mexico, Colombia, USA. Some of themareintroduced as follows. 3.6.1.Structuralmeasures A1 :Polyculture In ... for programme evaluators, Sage Publications, Beverly Hills,1 984 . [9] P.J.H.Schoemaker, C.C. Waid, A probabilistic dominancemeasureforbinarychoices:Analytic aspects of a ... In doingso,theconsensusontheproblemsand theirsolutionscanbereached.However,itis notedthatMCAissubjectiveinitsnature.In case the  quantitative data are available, quantitative analysis...

Ngày tải lên: 22/03/2014, 12:20

... goals, a 6-stage procedure for SRSD is adapted from the literature on SRSD (e.g. Graham and Harris [19]; Mason, Harris and Graham [ 18] ; Harris, Graham and Mason [20]; Chalk, Hagan-Burke and ... two main reasons. First, many autonomy experts suggest it as an option to approach the problem. According to Little [15], students are not automatically autonomous in the formal classroom. ... believes that autonomy helps learning and that learner training can contribute to promoting learner autonomy. Information about learner beliefs about language learning, learner autonomy and self-regulation...

Ngày tải lên: 28/03/2014, 11:20

... 31547–31554. 52 Nara K, Ito S, Ito T, Suzuki Y, Ghoneim MA, Tachib- ana S & Hirose S (1994) Elastase inhibitor elafin is a new type of proteinase inhibitor which has a transglu- taminase-mediated anchoring ... Malorni A & Marino G (1 988 ) Substance P as a transglutaminase substrate: identification of the reaction products by fast atom bombardment mass spectrometry. Anal Biochem 172, 499–503. 15 Hohenadl ... Facchiano AM, Facchiano A & Facchiano F (2003) Active sequences collection (ASC) database: a new tool to assign functions to protein sequences. Nucleic Acids Res 31, 379– 382 . 40 Kalinin A, ...

Ngày tải lên: 30/03/2014, 15:20

... and interpretation, manuscript writing; GMH: collection and/ or assembly of data, data analysis and interpretation, manuscript writing; CA: collection and/or assembly of data, data analysis and ... interpretation, manuscript writing; RS: data analysis and interpretation, manuscript writing. All authors read and approved the final manuscript. Additional material Acknowledgements The authors are ... Martin-Henao 4 , Carmen Azqueta 4 and Ramon Segura 2 Address: 1 Departament de Fisiologia - Biologia, Universitat de Barcelona, Av. Diagonal, 645 E- 080 28 Barcelona, Spain, 2 Departament de Ciències...

Ngày tải lên: 18/06/2014, 15:20

... Med 2004, 45:272-2 78. 19. Uchida K, Nakajima H, Miyazaki T, Yayama T, Kawahara H, Kobayashi S, Tsuchida T, Okazawa H, Fujibayashi Y, Baba H: Effects of Alendronate on bone metabolism in glucocorticoid-induced ... 29:1354-1359. doi:10.1 186 /2191-219X-1-4 Cite this article as: Cook et al.: 18 F-fluoride PET: changes in uptake as a method to assess response in bone metastases from castrate-resistant prostate cancer patients treated with 223 Ra-chloride ... ALP changes. Mean SUVmax, PSA and ALP changes at 6 and 12 weeks as a percentage of baseline levels in the five subjects (A to E). Table 1 Disease extent, measured metastatic sites and changes...

Ngày tải lên: 21/06/2014, 02:20

... are to infect new executables Metamorphic code is a code that can reprogram itself by translating its own code into a temporary representation, and then back to normal code again For example, ... reasons for creatin g and g spreading malware ã Research projects Viruses have been written as: ã Research projects ãPranks ãVandalism ã To attack the products of specific companies T di ib ... space ã Files have strange names which are not recognizable ã Programs act erratically ã Resources are used up easily ã Resources are used up easily Prevention is Better than Cure Do not accept...

Ngày tải lên: 31/07/2014, 04:20

... collagen in OF and OA cartilage. Ratio of aggrecan to type II collagen in the cartilage matrix of OA and OF femoral heads and comparison between areas (SP and IP). Aggrecan and type II collagen ... MMP-1 and (b) MMP-3 in articular cartilage from normal human femoral heads using ELISA. Values were normalised to total sol- uble protein, which was obtained after proteoglycan extraction and was ... in normal and in pathologic cartilage, the ratio of aggrecan to type II collagen was determined by ELISA. This ratio allows normalisation of data and elimination of variability due to carti- lage quality,...

Ngày tải lên: 09/08/2014, 08:22

... cur- rently available analgesic and anti-inflammatory drugs are clearly not adequate therapy. In addition to these classical available therapies, there are several reports regarding the use of disease-modifying ... rheumatoid arthritis. While other arthritis medicines attack symptoms such as inflammation, DMARDs actually treat the disease. It has been reported that DMARDs such as AZ, CQ, MTX and GS play an ... gastric and duodenal injury after the use of ibuprofen, aspirin, and other nonsteroidal anti- inflammatory agents. Am J Med 1 984 , 77:19-24. 12. Silva MA, Ishii-Iwamoto EL, Bracht A, Caparroz-Assef...

Ngày tải lên: 09/08/2014, 10:21

Ngày tải lên: 09/08/2014, 18:21

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Ngày tải lên: 11/08/2014, 14:21