c57bl 6j mice as a useful animal model for ef cacy studies with carotenoids
Báo cáo sinh học: "Assessment of a Poisson animal model for embryo yield in a simulated multiple ovulation-embryo transfer scheme" potx
... 222-230 Luciani JM, Guichaoua MR, Mattei A, Morazzani MR (1984) Pachytene analysis of a man with a 13q;14q translocation and infertility: behaviour of the trivalent and nonrandom association with the ... capacity of the heterozygous animals, SC formation and the behaviour of the trivalent 5/15; ;15 was studied at the pachytene stage of meiosis = MATERIALS AND METHODS Two Saanen male goats (Capra ... Meiotic association between the XY chromosomes and unpaired autosomal elements as a cause of human male sterility Cytogenet Cell Genet 39, 19-29 Solari AJ (1980) Synaptonemal complex and associated...
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Báo cáo sinh học: " Assessment of a Poisson animal model for embryo yield in a simulated multiple ovulation-embryo transfer scheme" pot
... the ith animal and e ! is the residual associated with the jth record on the ith animal Here (i * ui has null mean and variance a and eij has null mean and variance * exp(2p)exp(u ) £ = a e 2* ... the bias was larger for BLUE in all cases This apparent paradox can be explained by the fact that BLUE is an unbiased estimator of: and not exp(p + H Empirical biases for the methods, and their ... the situation dictates a nonlinear analysis, or a transformation of the data Clearly, is so variance), u Q = A linear one-way random effects model, however, can be contrived in which case be shown...
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Báo cáo y học: "Response of the mouse lung transcriptome to welding fume: effects of stainless and mild steel fumes on lung gene expression in A/J and C57BL/6J mice" pot
... dark) at a standard temperature (22-24°C) and 30-70% relative humidity Animals were acclimated to the animal facility for a minimum of week and allowed access to a conventional diet (6% Irradiated ... Shukla A, Barrett TF, Nakayama KI, Nakayama K, Mossman BT, Lounsbury KM: Transcriptional up-regulation of MMP12 and MMP13 by asbestos occurs via a PKCdelta-dependent pathway in murine lung FASEB ... DE) and quality was assessed on the Agilent 2100 Bioanalyzer (Agilent Technologies, Palo Alto, CA) MouseRef-8 v1.1 Illumina BeadChips Labeled cRNA, from an input RNA of 375 ng, was prepared according...
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BARRIER DISRUPTION IN STAT6VT TRANSGENIC MICE AS A POTENTIAL MODEL FOR ATOPIC DERMATITIS SKIN INFLAMMATION
... technical aspects of this project For Dr Ravi Sahu, Dr Mohammed Al-Hassani, Dr Sarita Sehra, Dr Simarna Kaur, Qiaofang Yi, Davina A Lewis, Badri M Rashid, Evelyn T Nguyen, and Pamela Durant And finally, ... a hairless rat model (Patil, Singh, Sarasour, et al., 1995) The radial spread of SLS can elicit increased TEWL and decreased skin capacitance in areas adjacent to the application sites, as far ... towards a TH2 bias at play in atopic diseases The STAT6VT transgenic mice spontaneously develop skin inflammation and have abnormalities in EDC genes as well as abnormal barrier function As a...
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Báo cáo khoa học: b3-Adrenoceptor knockout in C57BL/6J mice depresses the occurrence of brown adipocytes in white fat pptx
... mRNA and protein in WAT and BAT, as compared to wild-type (WT) controls Materials and methods Materials All organic and inorganic chemicals of analytical or molecular biology grade were purchased ... a section was measured using a Nikon Eclipse E800 connected with a digital Camera DXM1200 at a magnification of 20· The surface area of the cells was measured using the Nikon LUCIA IMAGE Version ... homogenate proteins were used to measure the cytochrome c oxidase activity by the method of Yonetani and Ray [28] Statistics Data are presented as mean ± SE and were analyzed using a two-factor analysis...
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Báo cáo hóa học: "Generalized cerebral atrophy seen on MRI in a naturally exposed animal model for creutzfeldtjakob disease" pot
... Yoshihara M, Tsunoda A, Sato K, Kanayama S, Calderon A: Differential diagnosis of NPH and brain atrophy assessed by measurement of intracranial and ventricular CSF volume with D FASE MRI Acta Neurochir ... acquisition and analysis, JMS–MRI data acquisition and analysis, BVT– Immunohistochemistry analysis at NVSL, PLH–Pathological assistance at New Bolton Center, RWS–Clinical assessment and medical care ... GS– Statistical analysis, CAD–Clinical assessment and integration of the obtained data, TEI– Integration of the data, DTA–Clinical integration of the data, DLS– Acquisition and coordination of...
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Báo cáo sinh học: "A reduced animal model with elimination of quantitative trait loci equations for marker-assisted selection" pdf
... matrices * t Z and L in equation [20] are written as For equation !19), the * matrix R is given as where for the non-parent animals and Therefore, each effect for the parent animals can be obtained by ... was derived from its parent animals Therefore, the needed additive effects of MQTL alleles or 2) for parent animals and vland Vkfor non-parent animals, are vi and v4 (k where v!represent the additive ... have as If one parent in parent of an ) (i) Var(v; animali is deleted unknown, rows and columns pertaining to this are EXAMPLE Six animals (animals 1-6) are considered for an illustration Marker...
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Báo cáo sinh học: " A reduced animal model approach to predicting total additive genetic merit for marker-assisted selection" ppsx
... written as of R , o as progeny be predicted from We use a small example data set including six animals, four animals and two animals with no progeny, as given in table I having progeny The total additive ... methodology for the application of best linear unbiased prediction (BLUP; Henderson, 1973, 1975, 1984) to MAS in animal breeding Using an animal model (AM) with additive effects for alleles at a marked ... because animals and are non-parents The solutions obtained by the current approach are the same as the corresponding ones calculated according to AMs of Fernando and Grossman (1989) and van Arendonk...
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Báo cáo sinh học: "Bayesian estimation of dispersion parameters with a reduced animal model including polygenic and QTL effects" pot
... similar parameterization (Ovc to obtain and B The conditional densities for the FAM are a special case of RAM (see ) RT table I ): all animals are in category and wz In case of O the conditional ... markers and quantitative trait loci for a granddaughter design, J Dairy Sci (1997) [28] VanRaden P.M., Wiggans G.R., Derivation, calculation and use of national animal model information, J Dairy ... density for a genetic variance component becomes standard (inverted gamma distribution) when a genetic effect is sampled for each animal in the pedigree, as in a (full) animal model (FAM) The...
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Báo cáo y học: " Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy" pptx
... well as according to animal care standards deemed acceptable by the Association for the Assessment and Accreditation of Laboratory Animal Care International (AAALAC) All experiments were performed ... subcutaneously with PMPA, 20 mg/kg/day, and FTC, 50 mg/kg/day Quantitative assay for SIVmac251 viral RNA levels For measurement of plasma SIVmac251 RNA levels, a quantitative TaqMan RNA reverse transcription-PCR ... housed at BIOQUAL, Inc Rockville, MD, according to standards and guidelines as set forth in the Animal Welfare Act and The Guide for the Care and Use of Page 14 of 19 Laboratory Animals, as well as...
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Báo cáo sinh học: " Genetic parameters for social effects on survival in cannibalistic layers: Combining survival analysis and a linear animal model" pdf
... pseudo-records with their associated weights are estimated using a linear animal model In this paper, we apply a similar two-step approach to estimate genetic parameters for direct and associative effects ... will refer to the linear animal model including associative effects as LAM and to the two-step approach as 2STEP Cross validation will be used to compare 2STEP with LAM [8,13] LAM was applied ... Data analysis Data were analysed separately for each line Two methods to estimate genetic parameters were compared: 1) LAM, a linear animal model including direct and associative effects applied...
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Báo cáo sinh học: "Breeding value prediction for production traits in layer chickens using pedigree or genomic relationships in a reduced animal model" docx
... in accuracy between GBLUP and PBLUP was smaller for selection at a later age than at an early age, when data on sibs of selection candidates were available (Figures and 2) This extra information ... individuals from the 290 available for validation based on EBV for each trait and comparing the average hatch-corrected phenotype of the selected individuals Marker based parental average (PA) EBV ... young age, before information on sibs of selection candidates is available The accuracies of methods that assume equal variance for all SNP, such as GBLUP and of those that allow differential weighting...
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Role of interleukin 13 on the development of minimal change nephrotic syndrome a novel animal model
... Singapore, June 2005 Abstract submitted for the 1st Congress of Asian Society for Pediatric Research had won a travel award and was also selected for oral presentation in the meeting which was ... et al, 2005) by its ability to degrade heparan sulfate glycosaminoglycan, a major component of the GBM Haemopexin, a 100 kDa vasoactive factor, has been investigated and characterized from patients ... subunits associate with tyrosine kinases of the Janus family Activation of JAKs initiates a series of downstream signal transduction events which leads to phosphorylation of STAT6, a transcription factor...
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Fault tree synthesis from a directed graph model for a power distribution network
... boundary and the boundary variables are treated as P0 / -S primal events The unit models describe both normal and failed behavior and depend on a wide variety of operating parameters and failure ... the causal relationships between variables including normal and failed states The basic elements of a digraph are shown in figure for conduction in a wire Node labels represent deviation variables, ... previously taught at MIT He is the author of over 100 books and papers dealing with process design and safety and reliability analysis He has worked for the Dow Chemical Company, Ethyl Corporation and...
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Tài liệu A COMPREHENSIVE QUANTITATIVE MODEL FOR ANALYZING BOND REFUNDING DECISIONS pptx
... refund a bond issue would have to be evaluated on a case by case basis to calculate the exact costs or savings produced by the various interacting variables Consequently, there is a need for an ... bond refunding analysis that has not been adequately treated to date is the analysis of a bond refunding proposal with overlapping interest For example, although Maris [6] included overlapping ... performance significantly better than the random selection and 100-basis-point benchmark models, but not significantly better than a stopping-time model based on present value analysis One aspect...
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Tài liệu Towards a conceptual reference model for project management information systems ppt
... that has a defined start and end date and is undertaken to reach a goal Therefore, an initiative may be a program, a project, a sub-project, a project phase, a work package, an activity or a task ... model as a template The reference model was used as the basis for a new DIN (German Institute for Standardization) project management data model standard A working group of the German Association ... Consequently, a system can ensure that all necessary approval steps are carried out before a project actually begins Each project plan can be archived as often as necessary by means of a plan version (PlanVersion)...
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Tài liệu Báo cáo khoa học: "A Hybrid Hierarchical Model for Multi-Document Summarization" ppt
... topics that are organized into hierarchies following (Haghighi and Vanderwende, 2009) A hierarchical model is particularly appealing to summarization than a ”flat” model, e.g LDA (Blei et al., 2003b), ... in that one can discover ”abstract” and ”specific” topics For instance, discovering that ”baseball” and ”football” are both contained in an abstract class ”sports” can help to identify summary ... (recall against unigrams), R-2 (recall against bigrams), and R-SU4 (recall against skip-4 bigrams) Experiment 1: sumHLDA Parameter Analysis: In sumHLDA we introduce a prior different than the standard...
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Tài liệu Báo cáo khoa học: "A Unified Graph Model for Sentence-based Opinion Retrieval" pdf
... development in information retrieval, pages 314-321 ACM Giambattista Amati, Edgardo Ambrosi, Marco Bianchi, Carlo Gaibisso, and Giorgio Gambosi 2007 FUB, IASI-CNR and University of Tor Vergata at TREC ... contextual information between the opinion and its corresponding target, Avatar in A and com- 1368 fortable (o1) are also regarded as relevant opinion mistakenly, creating a false positive In reality ... GORM achieved the best performance in all the evaluation metrics Our baseline, ROSC and GORM which were sentence-based approaches achieved better performance than the document-based approaches...
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Tài liệu Báo cáo khoa học: "A probabilistic generative model for an intermediate constituency-dependency representation" pptx
... Mladov´ , a a a s a ˇ Jana Sindlerov´ , Krist´ na Tomˇu, and Zdenˇ k a y s˚ e ˇ Zabokrtsk´ 2009 Tectogrammatical Annotation y of the Wall Street Journal The Prague Bulletin of Mathematical Linguistics, ... detect local (intra-clausal) coordinations, as illustrated by (Marinˇ iˇ et al., 2009) cc Table reports the results we obtain when reranking with our model an increasing number of k-best candidates ... Treebank Computational Linguistics, 19(2):313–330 Domen Marinˇ iˇ , Matjaˇ Gams, and Tomaˇ Sef 2009 cc z zˇ Intraclausal Coordination and Clause Detection as a Preprocessing Step to Dependency Parsing...
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Tài liệu Báo cáo khoa học: "A Joint Statistical Model for Simultaneous Word Spacing and Spelling Error Correction for Korean" pdf
... for each case: single Jaso transition case, two Jaso’s transition case, and more than two Jasos transition case In single Jaso transition case, the spelling errors are corrected by only one Jaso ... sentence Each Eumjeol in the sentence is decomposed into Jasos as above, and each Jaso has its own correction candidates For example, Jaso ‘ㅇ’ at 4th column has its candidates ‘ㅎ’, ‘ㄴ’ and ‘X’ And ... combination of Jasos, the number of all possible Eumjeols is much larger than that of all possible Jasos In other words, Jaso-based language model is smaller than Eumjeol-based language model Various...
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