công ty cổ phần tin học lạc việt
Báo cáo y học: "Association of serum markers with improvement in clinical response measures after treatment with golimumab in patients with active rheumatoid arthritis despite receiving methotrexate: results from the GO-FORWARD study" pdf
... markers were unable to achieve high enough specificity and sensitivity to be routinely useful predictors Thus, additional testing of serum and other types of markers from other studies will be needed ... Specificity = 48% Sensitivity = 80% R 17 67 Predictive Value NPV = 86% PPV = 36% Threshold = -1.3 Biomarker modela (n = 308) True/Predicted NR R Accuracy NR 137 87 Specificity = 61% Sensitivity = ... Specificity = 23% Sensitivity = 90% Predictive value NPV = 68% PPV = 55% Threshold = -0.35 Biomarker modela (n = 308) True/Predicted NR R Accuracy NR R 62 16 88 142 Specificity = 41% Sensitivity =...
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Báo cáo y học: "Potential bias in testing for hyperprolactinemia and pituitary tumors in risperidone-treated patients: a claims-based study" pps
... hyperprolactinemia Olanzapine × hyperprolactinemia Quetiapine × hyperprolactinemia Ziprasidone × hyperprolactinemia Haloperidol × hyperprolactinemia Perphenazine × hyperprolactinemia Duration of antipsychotic ... the more frequent diagnosis of hyperprolactinemia was the more frequent prolactin testing among risperidone-treated patients The frequency of prolactin tests in risperidone-treated patients was ... 0.0269), suggesting a 41% greater likelihood of prolactin testing among risperidone-treated patients with PPAEs compared with similarly symptomatic patients treated with 'other typicals' Interaction...
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Báo cáo y học: "Differential effects on BAFF and APRIL levels in rituximab-treated patients with systemic lupus erythematosus and rheumatoid arthritis" pot
... from all contributing individuals B-cell-related time points for analysis With the known variability in time to B-cell return after rituximab treatment and with the aim of correlating changes of ... Acknowledgements We express our gratitude to all participating patients as well as to the contributing nurses at the Rheumatology Clinic, Karolinska University Hospital We also thank Eva Jemseby, Margareta ... Stohl W, Metyas S, Tan SM, Cheema GS, Oamar B, Roschke V, Wu Y, Baker KP, Hilbert DM: Inverse association between circulating APRIL levels and serological and clinical disease activity in patients...
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Báo cáo y học: " Unintegrated HIV-1 provides an inducible and functional reservoir in untreated and highly active antiretroviral therapy-treated patients" potx
... replication-competent resting CD4+ T lymphocytes was less than HIV-Ag-SCs/107 resting CD4+ T cells For the other patients, resting CD4+ T cells generated 28.57 to 100 HIV-1-Ag-SCs/107 resting CD4+ T cells ... reservoir Resting CD4+ T lymphocytes secreting HIV-1 viral proteins in untreated Mobilization Mobilization of the functional preintegration reservoir Resting CD4+ T lymphocytes secreting HIV-1 ... HIV-1-Ag-SCs/107 resting CD4+ T lymphocytes were enumerated (mean, 106,435 HIV-1-Ag-SCs/107 resting CD4+ T lymphocytes), whereas unstimulated infected cells generated only
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Báo cáo hóa học: " Epidermal growth factor receptor gene copy number in 101 advanced colorectal cancer patients treated with chemotherapy plus cetuximab" doc
... of the twenty-one non-responders had an increased EGFR-GCN (p < 0.0001) However, there is no consensus on the predictive role of increased EGFR-GCN due to difficulty in reproducibility of the ... weeks Toxicity was graded according to the National Cancer Institute Common Toxicity Criteria (version 2.0) Pretreatment and Follow-Up Studies History, physical examinations, and a safety assessment ... patients Competing interests The authors declare that they have no competing interests Authors' contributions CC: study design, acquisition, analysis and interpretation of data; drafting the manuscript...
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Báo cáo y học: "Two-year Outcome of Turkish Patients Treated with Zotarolimus Versus Paclitaxel Eluting Stents in an Unselected Population with Coronary Artery Disease in the Real World: A Prospective Non-randomized Registry in Southern Turk
... artery disease of simple to moderate complexity (1-3) The use of the Zotarolimus-eluting stent (ZES; Medtronic Vascular, Santa Rosa, CA) for treating single de novo lesions in patients with symptomatic ... high-density lipoprotein; LDL, low-density lipoprotein; MI, myocardial infarction; SAP, stable angina pectoris; USAP, unstable angina pectoris Indicates patients who received zotarolimus-eluting stents ... points, clinical trials comparing the safety and efficacy between these DES types and BMSs have yielded inconsistent results In the ENDEAVOR I, II,II Continued Access Registry (CA) and III trials...
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Tài liệu Differences in 4-Year Health Outcomes for Elderly and Poor, Chronically III Patients Treated in HMO and Fee-for-Service Systems ppt
... primary care quality criteria indicated that those in FFS systems experienced shorter treatment queues and better comprehensiveness and continuity of care and rated the quality of their care more ... majority (54%) were female About 22% were at or below 200% of the poverty line; 16% of those reported being covered by Medicaid Three of 10 eligible for Medicare were also in the poverty group ... scores estimated using the internal-consistency reliability method The construction of summary measures, score reliability and validity, and normative and other interpretation guidelines are...
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Predictors of relapse among pulmonary tuberculosis patients treated in a DOTS programme in South India pot
... and sensitivity testing London, UK: Butterworth, 1968 Canetti G, Fox W, Khomenko A, et al Advances in techniques of testing mycobacterial drug sensitivity, and the use of sensitivity tests in ... No Yes Drug regularity Regular Irregular Drug sensitivity profile—0 months Sensitive Resistant to H and/or HR Smear conversion at months Yes No Initial smear grading Scanty, 1ϩ 2ϩ, 3ϩ Initial ... regularity of treatment, weight and smoking and drinking habits (data not shown) As per our definition for relapse in this study the rate of relapse was 12.3% (62/503 patients) The majority of the...
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Báo cáo hóa học: " Updated survivals and prognostic factor analysis in myeloma treated by a staged approach use of bortezomib/thalidomide/dexamethasone in transplant eligible patients" pot
... account for the differential VAD chemosensitivity As chemosensitivity is an important risk factor for survival, we postulated that the higher chemosensitivity might indeed translate into superior EFS ... data, analysis and interpretation of data, writing and approval of the manuscript Competing interests The author declares that they have no competing interests Received: 27 July 2010 Accepted: ... prognostic factors OS 0.081 0.211 Age (median) 0.828 0.770 Paraprotein subtype ISS 0.382 0.026 0.393 0.645 VAD chemosensitivity 0.887 0.974 VGPR after induction 0.722 0.406 VGPR after auto-HSCT 0.181...
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Báo cáo hóa học: "DNA polymeraseh protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy" pot
... low in gastric cancer, due to subjectivity, the error of IHC counting could be bigger, which may influence the sensitivity and specificity when predicting treatment response, so more accurate ... when the cells were treated with carboplatin and oxaliplatin [25] Recent data show that polh mRNA level negatively correlated with cisplatin sensitivity of non small cell lung cancer (NSCLC) ... oxaliplatin sensitivity of gastric cancer cell lines and the significance of that in predicting treatment response and survival of metastatic gastric cancer patients treated with oxaliplatin-based...
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báo cáo hóa học:" Nuclear survivin expression is a positive prognostic factor in taxane-platinum-treated ovarian cancer patients" pdf
... disease-free survival; HPS: high platinum sensitivity; ID: ID score; OS: overall survival; PC/PAC: platinum/cyclophosphamide chemotherapy; PS: platinum sensitivity; TP: taxane-platinum chemotherapy Acknowledgements ... (cisplatin-cyclophosphamide or carboplatin-cyclophosphamide) or PAC chemotherapy (PC and doxorubicin) (244 patients), or with taxane-platinum chemotherapy (TP: paclitaxel or docetaxel with cisplatin ... antiapoptotic and proliferation-stimulating survivin activity TP53 may play a part in negative survivin regulation Studies on cancer cell lines have shown that the wildtype TP53 repressed survivin at...
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báo cáo hóa học:" Substitutions in the Reverse Transcriptase and Protease Genes of HIV-1 Subtype B in Untreated Individuals and Patients Treated With Antiretroviral Drugs" potx
... Prasad VR: The influence of 3TC resistance mutation M184I on the fidelity and error specificity of human immunodeficiency virus type reverse transcriptase Nucleic Acids Res 1998, 26:3066-3072 Abstract ... RT was limited to positions 38249 due to the type of assay performed Sequencing of both the RT and PR genes was also employed to determine the subtypes of these viral isolates in concert with ... http://hivdb.stanford.edu/ Nucleotide genomic diversity in the RT and PR regions of the various viral isolates was compared with a consensus subtype B reference virus, LAV-1 (http://www.hiv.lanl.gov;...
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báo cáo hóa học: " F-fluoride PET: changes in uptake as a method to assess response in bone metastases from castrate-resistant prostate cancer patients treated with 223Ra-chloride (Alpharadin)" pdf
... manuscript drafting and approval AKA study design, coordination of study, manuscript drafting and approval VL study design, data acquisition, analysis, manuscript drafting and approval Competing interests ... acquisition, analysis, manuscript drafting and approval CP study design, coordination of study, manuscript drafting and approval SC data acquisition, manuscript drafting and approval BJ coordination ... tumour activity by measuring parameters that primarily reflect osteoblastic activity (i.e ALP and 18 F-fluoride uptake) is a temporal discordance in changes with intrinsic tumour activity Although...
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Báo cáo y học: "Primary Care Outcomes in Patients Treated by Nurse Practitioners or Physicians" docx
... small group practices The providers were faculty from a university medical center, hence were not necessarily typical of those in nonacademic practice settings The patients were predominantly immigrants ... physicians were able to function equally as primary care providers The ability to this type of study, even in a setting atypical for some patients, adds significant weight to the results from prior ... eligible for hospital admitting privileges, either by regulating access at the state level or by allowing local hospital boards to decide The combination of authority to prescribe drugs, direct...
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Báo cáo y học: "Brain choline concentrations may not be altered in euthymic bipolar disorder patients chronically treated with either lithium or sodium valproate" pps
... seenhuman brain at 3.0 T A A typical A typical 1H-MRS spectrum of the human brain at 3.0 T A number of metabolites can be seen 1: creatine (methylene) + phosphocreatine, 2: glutamate + glutamine, ... completed this study Of the 14 bipolar patients taking lithium, were Type I and were Type II In the valproate group, were Type I and were Type II These groups were studied both separately and together, ... that only patients meeting diagnostic criteria for Bipolar Disorder Type I were included, and they had to be on sodium valproate monotherapy This was done to examine Bipolar Type I patients in more...
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Báo cáo y học: "Serum cartilage oligomeric matrix protein (COMP) decreases in rheumatoid arthritis patients treated with infliximab or etanercept" pot
... marker of the disease process in RA, which should be useful for evaluating novel treatment modalities in the disease Competing interests TS and DH are share-holders in AnaMar Medical Acknowledgements ... Reumatism, the Crafoord Foundation, the Nanna Svartz foundation, and the Medical Faculty of Lund University The skilful technical assistance of Mrs Mette Lindell is appreciated References Welsing ... Swinkels HL, Kiemeney LA, van Riel PL: The relationship between disease activity, joint destruction, and functional capacity over the course of rheumatoid arthritis Arthritis Rheum 2001, 44:2009-2017...
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Báo cáo y học: "Circulating tumour necrosis factor-α bioactivity in rheumatoid arthritis patients treated with infliximab: link to clinical respone" pot
... patients are summarized in Table Bioassay for circulating TNF-α bioactivity A functional assay for TNF-α activity was designed using the ability of RA synoviocytes to produce IL-6 and OPG in response ... production (n = 20; r = 0.843; P < 0.001) Circulating TNF-α bioactivity modulation by the ninth infusion Patients with high circulating bioactivity at the first infusion could be separated into ... one had a poor response (ACR ≤ 20) No modulation in circulating bioactivity was observed in patients with low circulating TNF-α bioactivity before infliximab therapy (n = 8; Fig 4c) A link was observed...
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Báo cáo y học: "Cytokine polymorphisms influence treatment outcomes in SLE patients treated with antimalarial drugs" ppsx
... genotype [31] Several authors have also proposed the use of Table IL-10 and TNFα genotypes of systemic lupus erythematosus patients stratified by treatment Treatment TNFα genotype IL-10 genotype ... between IL-10 and TNFα genotypes in regulating the response to antimalarial treatment in SLE patients A strong association was found between carriage of the combined genotype low IL-10/high TNFα ... producer genotype and good response to antimalarial drugs (OR 2.25, 95%CI 1.11–4.58, p = 0.024), whereas the IL-10 genotype did not show any significant association However, when combined genotypes...
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Báo cáo khoa học: "Randomized controlled trial of live lactobacillus acidophilus plus bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients" pot
... permeability of the mucosal cells and in intestinal motility [9,10] The ingestion of lactic acid bacteria has been extensively investigated as a beneficial dietary adjunct for gastrointestinal disorders ... her help in editing of this manuscript Author Details 1Department of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand, 2Department of Medicine, Faculty of Medicine, ... due to lactobacillus strains [12-15] Since dysbiosis of the intestinal flora may be a promoting factor in radiotherapy-related intestinal problems, lactobacilli could be used to achieve a more balance...
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Báo cáo khoa học: "Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy" pot
... tissue complication probability (NTCP) [8,12,13] value and relative volume of lung receiving more than a threshold dose (Vdose) [7,10,14-19] Technology such as intensity-modulated radiotherapy (IMRT) ... radiation pneumonitis were found to be associated with a variety of clinical parameters (see Additional file 1) Sex, age, smoking history, pre-existing pulmonary disease, performance score and pulmonary ... parameters predictive of risk of RP as reported in the literature Competing interests The authors declare that they have no competing interests in this study Authors' contributions GZ and AS participated...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25