building biological memory by linking positive feedback loops
Báo cáo khoa học: A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts pptx
... importance of post-translationalfeedbacks, but have generally neglected transcriptional feedback loops. A recent analysis has shown that tran-scriptional feedback regulation by short-lived inhibi-tory ... influence ofpost-translational feedback loops on the dynamicbehavior of this signaling cascade has been unveiled,and it was found that there are positive and negativefeedbacks, depending on the ... identifying feedback adaptationmechanisms within the MEK ⁄ ERK signaling cascade by first scanning MAPK target genes for potentialfunctions in MAPK signaling. Candidate transcrip-tional feedback loops...
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Báo cáo khoa học: Novel suppression mechanism operating in early phase of adipogenesis by positive feedback loop for enhancement of cyclooxygenase-2 expression through prostaglandin F2a receptor mediated activation of MEK⁄ ERK-CREB cascade doc
... compilation ê 2011 FEBS Novel suppression mechanism operating in early phase ofadipogenesis by positive feedback loop for enhancementof cyclooxygenase-2 expression through prostaglandin F2areceptor ... the earlyphase of adipogenesis by enhancing the binding of CREB to the COX-2 pro-moter via FP receptor activated MEK ⁄ ERK cascade. Thus, PGF2aforms a positive feedback loop that coordinately ... synthesized by the acti-vation of FP receptor and that this effect was abol-ished by the co-treatment with the FP receptorantagonist or MEK inhibitor (Fig. 4). The inhibitionof PG biosynthesis by...
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Tài liệu Building Collaborative Solutions by Using Microsoft® Outlook® 2000 doc
... 1593A Released: 9/99 Delivery Guide Building Collaborative Solutions by Using Microsoftđ Outlookđ 2000 viii Building Collaborative Solutions by Using Microsoftđ Outlookđ 2000 The ... vi Building Collaborative Solutions by Using Microsoftđ Outlookđ 2000 Module 14: Site Server Integration Overview 1 Expanding Search Options 2 Creating a Custom Search Solution 6 Building ... Deploying an Outlook 2000 Solution 3:45 4:15 Lab A: Deploying the Move Application Building Collaborative Solutions by Using Microsoftđ Outlookđ 2000 v Customizing Team Folder Templates 28 Lab...
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Báo cáo khoa học: "building user interfaces with natural language feedback" pdf
... contribute to future version of the library areas follows.205 WYSIWYM — building user interfaces with natural language feedback Roger Evans and Richard PowerInformation Technology Research ... creates a filler of the specifiedtype, and regenerates the feedback text:Swallow two tablets with a glass of some liquidThe revised feedback text introduces a new an-chor, through which the ... through which the author can specify that theliquid in the glass is water. Thus by direct manip-ulation of the feedback text, our SME author hascreated a knowledge fragment equivalent to thisfeature...
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Tài liệu Building Continuous-Feedback Buttons pptx
... < Day Day Up > Building Continuous -Feedback Buttons It's sometimes useful to have actions executed continually while ... button is being clicked. A button set up to enable continuous execution is known as a continuous -feedback button—and a scroll button (the focus of this exercise) is a perfect example. If you ... continuously until the button is released. In Flash, you can create this type of functionality by using the onEnterFrame clip event with a button, as we'll soon demonstrate. In this exercise,...
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Tài liệu HOW TO USE YOUR MEMORY TO EARN MORE MONEY - By Phillip Newton ppt
... author.Manufactured in the United States of America.HOW TOUSE YOUR MEMORY TO EARN MOREMONEYHOW TOUSE YOUR MEMORY TO EARN MOREMONEY By Phillip Newton Page 3IntroductionIntroductionA little known ... most part, no. They developed their memory by applyingsome very simple techniques. This booklet will help you do the same.The benefits of improving your memory will quickly becomeapparent, ... properly.An older person can have a better memory than a younger one: itall depends on how well his mind is trained, and the techniques heuses to improve his memory. Your environment is also important...
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Tài liệu Smear microscopy and culture conversion rates among smear positive pulmonary tuberculosis patients by HIV status in Dar es Salaam, Tanzania ppt
... who had a persis-tent positive microscopy and/or cultur e were followedup again at the 8thweek with the same test ing as by theend of week 2.Thosewhowerestillpositivebymicroscopyand/orculture ... higher in HIV positive (72.8%) than HIV negative(63.3%) patients by univariate analysis(P = 0.046), but not in multivariate analysis. Alsoafter two weeks of treatment the conversion rate by fluorescence ... microscopy was higher in HIV positive (72.8%)than in HIV negative(63.2%) patients by univariate analysis (P = 0.043) but not in the multivariate analysis. The con-version rates by both methods during...
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Tài liệu Báo cáo khoa học: Metabolic control of mitochondrial properties by adenine nucleotide translocator determines palmitoyl-CoA effects Implications for a mechanism linking obesity and type 2 diabetes pdf
... increase the positive control of the ATPin⁄ADPinratio by ATP synthesis and the negative control by the proton leak. The negative control of the ATPin⁄ADPinratio by the ANT increased by 100% ... ADPratios: the former decreased by 63 ± 4%, and the lat-ter increased by 352 ± 34%. The reduced to oxidizedcoenzyme Q ratio (QH2⁄ Q) increased by 42 ± 9%,and Dw increased by 13 ± 1 mV (9%). The QH2⁄ ... tooxidized coenzyme Q (QH2⁄ Q) by 42 ± 9%, Dw by 13 ± 1 mV (9%), andthe intramitochondrial ATP ⁄ ADP ratio by 352 ± 34%, and decreases theextramitochondrial ATP ⁄ ADP ratio by 63 ± 4% in actively phosphorylat-ing...
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Tài liệu Báo cáo khoa học: "Three BioNLP Tools Powered by a Biological Lexicon" doc
... section focuses on the words and derivational relations of words that are covered by our BioLexicon but not by comparable existing resources. Figures 1 and 2 show the percentage of the terminological ... 3 April 2009.c2009 Association for Computational Linguistics Three BioNLP Tools Powered by a Biological Lexicon Abstract In this paper, we demonstrate three NLP applications of the ... general English thesaurus which additionally covers biological terms. However, since WordNet is not targeted at the biology domain, many biological terms and derivational relations are missing....
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Báo cáo khoa học: Endogenous tetrahydroisoquinolines associated with Parkinson’s disease mimic the feedback inhibition of tyrosine hydroxylase by catecholamines doc
... initial loss of hTH activity caused by DA but had no effect onhTH inhibition by NMNorsal or Norsal (n = 4).J. Scholz et al. TIQs imitate mechanisms of TH feedback inhibitionFEBS Journal 275 ... Short-term regulation of TH activity includes feedback inhibition by catecholamine end products,allosteric modulation and phosphorylation-dependentactivation by various kinases [22,23].Using recombinant ... for 2 min at 30 °C under aerobicconditions, we terminated the reaction by adding 1.1% per-chloric acid. For hTH activation by PKA, we reconstitutedthe protein samples with Fe(II) as described...
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