body or of those who die in adam and of those who are made alive in christ
Báo cáo khoa học: "Pro/con debate: In patients who are potential candidates for organ donation after cardiac death, starting medications and/or interventions for the sole purpose of making the organs more viable is an acceptable practice" doc
... that starting certain medications and interventions such as inotropes, vasopressors, heparin and phentolamine in potential donors for the sole purpose of making the organs in DCD more viable ... heparin and phentolamine are two interventions often considered Most DCD donors are individuals with neurological injury, and heparin poses more than a theoretical risk of precipitating or exacerbating ... principle of the ‘rule of double effect’ provides moral justification for the provision of certain forms of care at the end of life that result in death [11] A practical example of this principle...
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Báo cáo khoa học: Structural and biological effects of a b2- or b3-amino acid insertion in a peptide Application to molecular recognition of substance P by the neurokinin-1 receptor ppt
... structural and biological consequences of a single b-amino acid incorporation When Phe7 or Phe8 are replaced by b2-HPhe, the corresponding analogues are weak competitors of specific NK-1 binding sites ... searches of b-amino acids were initially carried out at intervals of 30° for each torsion angle /, h, and w and were subsequently refined by varying /, w angles in intervals of 10° and setting h ... Regarding the minor binding site NK-1m, SP and [Pro9]SP show a 10-fold increase in affinity compared to their affinity for the NK-1M binding site, with Ki in the subnanomolar range (0.13 nM) and...
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Báo cáo Y học: Interaction of the anterior fat body protein with the hexamerin receptor in the blowfly Calliphora vicina pot
... detected in the anterior fat body and the haemocytes A light signal only appears in the central fat body; no signal was obtained in the posterior fat body Looking for binding partners of the hexamerin ... (1995) Ecdysterone-mediated uptake of arylphorin by larval fat bodies of Calliphora vicina: involvement and developmental regulation of arylphorin binding proteins Insect Biochem Mol Biol 25, 799–806 ... uptake of storage protein in this part of the tissue This study opens the way to further experiments in two distinct areas On the one hand, the binding domains of AFP and the hexamerin receptor could...
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A survey of technology thinkers and stakeholders shows they believe the internet will continue to spread in a “flattening” and improving world. There are many, though, who think major problems will accompany technology advances by 2020 doc
... the Internet Engineering Task Force “Random acts of senseless violence and destruction will continue and expand due to a feeling of 21st century anomie, and an increasing sense of lack of individual ... tasks for a user: sorting email according to preference, filling out Web page forms with stored information, reporting on company inventory levels, observing changes in competitors' prices and relaying ... to a “singularity” is predicted by some Respected professor and author Vernor Vinge and inventor Ray Kurzweil – author of The Singularity is Near and a winner of the U.S National Medal of Technology...
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Báo cáo y học: "A functional variant of Fcγ receptor IIIA is associated with rheumatoid arthritis in individuals who are positive for anti-glucose-6-phosphate isomerase antibodies" doc
... full design and coordination of the study, and DG, SI and AT participated in writing the discussion Acknowledgements This work was supported in part by the Japanese Ministry of Science and Culture ... the lack of association with individual FCGR polymorphisms in the whole cohort, our studies suggest that FCGR3A-158V/F polymorphisms play a crucial role in RA among those individuals who are positive ... either histidine [H] or arginine [R]) alters the ability of the receptor to bind to certain IgG subclasses [9,10] In RA patients, FCG3A-158V/F polymorphisms were reported to be frequent in UK Caucasian,...
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Báo cáo y học: "Dipeptidyl peptidase IV activity and/or structure homologs: Contributing factors in the pathogenesis of rheumatoid arthritis" doc
... stimulation of indicated cell function; dashed lines indicate abrogation of cell function and /or release of indicated mediator ‘Endogenous opioids’ include enkephalins, endorphins, dynorphin and endomorphin ... Furthermore, the residual activity in the CD26 knockouts could not be inhibited by the DPPIV inhibitor valine-pyrrolidide Accordingly, multifactorial analysis of inhibitor panels and antibody-binding ... expression and the rapid upregulation and sustained signal following activation supports a role for CD26 in maintaining and regulating stimulation Although crosslinking of CD26 with CD3 leads to increased...
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Báo cáo y học: "Phenotype and in vitro function of mature MDDC generated from cryopreserved PBMC of cancer patients are equivalent to those from healthy donors" ppt
... for the mixed success of clinical trials reported so far Increased understanding of tumor-host interactions may help uncover these phenomena and allow better harnessing of the immune system for ... surface expression of DC-SIGN (CD209), CD83, CD86, and HLA-DR, intracellular expression of IL-12 and COX-2, secretion of inflammatory cytokines, and proliferation of allogeneic and antigenspecific ... result of http://www.jibtherapies.com/content/5/1/7 maturation [17,18] The cytokine repertoire of DC matured in the presence of inflammatory stimuli comprises pro-inflammatory cytokines and chemokines,...
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Báo cáo y học: " Inhaled salmeterol and/or fluticasone alters structure/function in a murine model of allergic airways disease" potx
... for S compared to N, FS, and F † in Total cells p < 0.05 for N, F and FS compared to S * in MAC p < 0.05 for S compared to V and FS † in MAC p < 0.05 for V and FS compared to S for Pearson correlations ... thickening, was essentially abrogated (Figures 4, 6, and 7) and correspondingly, methacholine responsiveness was returned to (or remained at) baseline levels (Figure 5) These findings are in keeping ... for S compared to V, N, F, or FS Panel with H: * p < 0.05 for S compared to V (p is also < 0.05 for S compared to N, F, or FS) † p < 0.05 for S or V compared to N, F, or FS All comparisons in...
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Báo cáo y học: " Role of ADAM and ADAMTS metalloproteinases in airway diseases" pot
... metalloproteinase domain with its catalytic consensus site is active in only about half of ADAM proteinases The following domains are characteristic of ADAMs and include a disintegrin domain mediating ... subfamily of proteinases also belonging to the metzincins (zinc-bearing proteinases) and structurally related to MMPs: the ADAMs (A Disintegrin And Metalloproteinase) [10-14] ADAM proteinases have ... organization of MMPs, ADAMs and ADAMTS Structural organization of MMPs, ADAMs and ADAMTS The typical structure of MMP is made of a prodomain, a furin cleavage site (all MT-MMPs, MMP-21,-23, and...
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Báo cáo y học: "Ave, CESAR, morituri te salutant! (Hail, CESAR, those who are about to die salute you!)" ppsx
... strategy for patients with severe respiratory failure Competing interests The authors declare that they have no competing interests Author details Clinical Fellow, Department of Critical Care Medicine, ... Strengths of the trial were an early assignment to treatment groups, intention-to-treat analysis, incorporation of transport risk into trial design, and a robust economic analysis The forethought of ... Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA 2Assistant Professor, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh,...
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Báo cáo y học: "Extracorporeal life support for management of refractory cardiac or respiratory failure: initial experience in a tertiary centre" docx
... vasoactive support, and prone positioning were maintained or initiated according to clinical conditions ECLS for hemodynamic support The use of ECLS for cardiac support was reserved for cases of cardiac ... our ECLS system in terms of speed of response, no patient receiving extracorporeal support for cardiac arrest survived In a large series of patients on extracorporeal support for in hospital cardiac ... Anesthesia and Intensive Care, Faculty of Medicine, University of Florence, Italy, 3Cardiac Surgery, Heart and Vessel Department, Careggi Teaching Hospital, Florence, Italy and 4Intensive Cardiac Coronary...
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In vitro and in vivo study of ABT 869 in treatment acute myeloid leukemia (AML) alone or in combination with chemotherapy or HDAC inhibitors insight into molecular mechanism and biologic characterization
... Nanjing, M.sc National University of Singapore) A THESIS SUBMITTED FOR THE DEGREE OF DORCTOR OF PHILOSOPHY DEPARTMENT OF MEDICINE YONG LOO LIN SCHOOL OF MEDICINE NATIONAL UNIVERSITY OF SINGAPORE ... My daughter Nina who is always at the center of my heart and my wife and soul mate Liqin for encouraging me and doing most of housework These studies were made possible by Singapore Cancer Syndicate, ... overexpression of survivin are the main mechanism of resistance to ABT-869, suggesting potential targets for reducing resistance developed in patients receiving FLT3 inhibitors Our findings may indicate...
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Báo cáo y học: " A Dietary Supplement Containing Standardized Phaseolus vulgaris Extract Influences Body Composition of Overweight Men and Women"
... portion of a 2000- to 2200-calorie diet, a dietary formula containing Phaseolus vulgaris extract as the major ingredient produced significant decreases in body fat while essentially maintaining ... The candidates were entered into a 2-week single-blinded, run -in to enrollment and randomization Subjects in this run -in period unknowingly received just placebo: the investigators were aware ... presence of a representative of the sponsor and of the Principal Investigator, and the representative formulas of the samples were identified Table A general summary of the meal plan used in the...
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Tài liệu Fixing Market Failures or Fixing Elections? Agricultural Credit in India pptx
... estimates are reported in column (2) of Table For public sector banks, the coe¢ 21 In scheduled election years, the margin of victory of the incumbent party is used The margin of victory of the majority ... constituencies in a district in which the incumbent enjoys a positive margin of victory (Fp ), and computing the average of these positive + f+ margins of victory M d , and de…ning the positive margin of ... (0.03) Margin of Victory Abs (Margin of Victory) Positive Margin of Victory Negative Margin of Victory Positive Margin * Cycle Dummy Positive Margin * Four Years until Election Positive Margin * Three...
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Tài liệu Why Should 5000 Children Die in India Every Day? Major Causes and Managerial Challenges pptx
... death for infants in India 2001-03 Top ten causes of death for children of to years of age in India 2001-03 Knowledge and Use of ORS in mothers of children less than years of age Morbidities in children ... coverage of Measles Vaccine has been increasing since its introduction in 1985, touched a peak of 80 % coverage in 1997 and has remained between 60 % and 70 % in the last few years While the WHO- UNICEF ... every day India’s child heath indicators are poor even compared with our Asian neighbors, namely Malaysia, Sri Lanka, Thailand, Vietnam, China, Nepal and Bangladesh Within India, the states of Bihar,...
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Tài liệu Báo cáo khoa học: Transactivation properties of c-Myb are critically dependent on two SUMO-1 acceptor sites that are conjugated in a PIASy enhanced manner pptx
... role of sumoylation in PML nuclear bodies where it is important for PML nuclear body dynamics and for recruiting other nuclear body components [28] In the present study we have extended the findings ... strongest interaction partners of c-Myb as judged by a low-copy bait screening in a cDNA library containing million independent clones, lending further support to the importance of the c-Myb–Ubc9 interaction ... screening shows that the SUMO-1 conjugase Ubc9 is one of a few major Myb-interacting proteins expressed in bone marrow or erythroleukemia cell lines We believe these independent data are important...
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Who Are America’s Poor Children? Examining Health Disparities Among Children in the United States ppt
... these vaccines.15 This report finds that this goal has been attained for 75 percent of poor infants and 78 percent of nonpoor infants (data are not shown) Our findings mirror those of the National ... mother and children’s health needs, offering informed advice about prenatal care, delivery, and newborn care, and assisting in preparing a safe home for newborn care Although currently present in ... health: Efforts to reduce parental smoking Two of the most troubling findings of this report are that more than one-quarter of poor children live in a family with someone who smokes every day, and nearly...
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Báo cáo khoa học: The ATPase activities of sulfonylurea receptor 2A and sulfonylurea receptor 2B are influenced by the C-terminal 42 amino acids doc
... Vmax of 2.52 nmol PiÆminÆmg)1 and an offset of 0.1 nmol PiÆminÆmg)1 for SUR2A, and a Km of 41 lM, a Vmax of 0.73nmol PiÆminÆmg)1 and an offset of 0.05 nmol PiÆminÆmg)1 for SUR2B 2.5 2.0 1.5 1.0 ... supporting information supplied by the authors Such materials are peer-reviewed and may be re-organized for online delivery, but are not copy-edited or typeset Technical support issues arising ... domains (TMDs) and two intracellular nucleotide-binding domains (NBDs) It is thought that, as in other ATP-binding cassette (ABC) proteins [4], the NBDs of SUR associate in a head-to-tail conformation...
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Báo cáo khoa học: The sulfur atoms of the substrate CoA and the catalytic cysteine are required for a productive mode of substrate binding in bacterial biosynthetic thiolase, a thioester-dependent enzyme doc
... entrance of the pantetheine-binding cavity is coloured orange Note how the CoA interacts mainly with the loop domain and Cys89 (C) A detailed view of the surroundings of the terminal moiety of CoA in ... chains point into the pantetheine binding tunnel: Ser247 and His156 Ser247 is known to adopt two different conformations; in the unliganded form, it points away from the tunnel, and, in the liganded ... be important for increasing the affinity of binding, as well as the solubility of the substrate Interestingly, the side chain of Ser247 points away from SPP, as previously seen in unliganded thiolase;...
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Credit for the Elderly or the Disabled For use in preparing 2012 Returns docx
... Substantial gainful activity is the performance of significant duties over a reasonable period of time while working for pay or profit, or in work generally done for pay or profit Full-time work (or part-time ... Limit Worksheet in the instructions 22 Credit for the elderly or the disabled Enter the smaller of line 20 or line 21 Also enter this amount on Form 1040A, line 30, or include on Form 1040, line ... services are available by phone Ordering forms, instructions, and publications Call 1-800-TAX-FORM (1-800-829-3676) to order current-year forms, instructions, and publications, and prior-year forms and...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25