basic model of the role of aptitude and motivation in second language learning
Revised version for the consideration of Contact Committee of the Heads of the SAIs of the European Union docx
... Audit Institutions of the Member States of the European Union and the European Court of Auditors, during the Meeting on 6-7 December 2004 in Luxembourg, took note of and discussed the “Guidelines ... Securing the quality of the on-going work; the on-going work should be subject to continual review. This review is essential to maintain the quality of audit work and to promote learning and ... audited (including a summary of the results of previous audits and their impacts); 3. Reasons for the audit; 4. Factors affecting the audit, including those determining the materiality of matters...
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Báo cáo khoa học: Studies on the role of the receptor protein motifs possibly involved in electrostatic interactions on the dopamine D1 and D2 receptor oligomerization pdf
... sub-unit of the G protein and not in the other case.Although there is discussion in the literature concern-ing the possibilities of photoconversion of YFP into aCFP-like species during acceptor ... traf-ficking properties. The binding experiments alsopointed to a decrease in the density of the D2R vari-ants in the cellular membrane; the number of D2receptor binding sites decreased with the ... localization of these proteins in the cell rather thanfrom the possible role of the D2R basic domain in the mechanism of D1–D2receptor heterodimerization. However, we find that the acidicepitope...
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Báo cáo khoa học: The essential tyrosine-containing loop conformation and the role of the C-terminal multi-helix region in eukaryotic phenylalanine ammonia-lyases docx
... MIOs).Constructing the ‘Tyr-loop-out’ variants of the bacterial PALs The ‘Tyr-loop -in models PlPAL in and SmPAL in weremodified by replacing residues 50–85 (PlPAL in ) and 34–68(SmPAL in ) with the corresponding ... which may be interpreted bythis hypothesis. The hypothesis will also be extendedto the analysis of the possible role of C-terminalmulti-helix domain in this process.Investigation of bacterial ... decrease in activity in both PAL [39] and HAL [38], we decided to study the behavior of the Tyr110-loop in PAL in moredetail.Results and discussionModeling the active conformation of the essential...
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WORKING PAPER NO. 218 THE ZERO-INTEREST-RATE BOUND AND THE ROLE OF THE EXCHANGE RATE FOR MONETARY POLICY IN JAPAN potx
... interest rate. The left-hand panels of Figure 5 report the upward bias in the mean real rate and the downward bias in the variability of the real rate depending on the level of the nominal equilibrium ... timethat the nominal interest rate is constrained. The results are summarized in Figure 7,which compares the biases in the means and standard deviations of output and in ation ECB ã Working Paper ... appreciation bias in the mean of the real exchange rate and the downward bias in its variability as shown in the right-hand panels of Figure 5. Thisreduction in the stabilizing function of the real exchange...
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Tài liệu Báo cáo Y học: Evolution of the enzymes of the citric acid cycle and the glyoxylate cycle of higher plants pdf
... provideinsights into the origin of its individual enzymes.However, the study of the enzymes of the tricarboxylicacid cycle necessarily also entails the s tudy of the severalenzymes involved in ... compartmentalized in the glyoxysomes of plants [31], the single exception being aconitase, w hich islocalized in the c ytosol [32,33]. Here we investigate the evolution of the enzymes of the pyru vate ... complex, the tricarboxylic acid cycle, and the glyoxylate cycle by examining t he individual phylogenies of the 21 s ubunits comprising the 14 enzymes of thesepathways as they occur in eukaryotes,...
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Managing diffuse water pollution in South East Queensland: An analysis of the role of the Healthy Waterways Partnership docx
... and the office comprises of a staff of 14 professionals. The Partnership received a total of $5.7 million for the period 2008-2009 with the main contributors to the funding being DERM and the ... by population growth and the world demand for mineral commodities, the economic prospects of the mining and mineral sector in South East Queensland, and more generally in the State, are especially ... out on the research side of the project, in terms of identifying the key Managing diffuse water pollution in SEQ: an analysis of the role of the Healthy Waterways Partnership – Cottingham,...
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Báo cáo khoa học: Structural and functional analysis of the interaction of the AAA-peroxins Pex1p and Pex6p pptx
... hydrolysis of the nucleotide. To investi-gate the in uence of the binding and ⁄ or hydrolysis of ATP on the interaction of the AAA-peroxins, Pex1p and Pex6p carrying mutated ATP-binding sites ... do interact in vivo. We assigned their corresponding binding sites and elucidated the importance of ATP-binding and -hydrolysis of Pex1p and Pex6p for theirinteraction. We show that the interaction ... interaction. This in turn is in line with the previous observation that adistinct point mutation in the vicinity of the WalkerAmotif in Pex1pD2 attenuates the interaction of bothAAA-peroxins...
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Báo cáo khoa học: ATP-binding domain of heat shock protein 70 is essential for its effects on the inhibition of the release of the second mitochondria-derived activator of caspase and apoptosis in C2C12 cells potx
... indicating that interaction with Smac is notrequired with respect to the role of HSP70 in the inhi-bition of the release of Smac and apoptosis. The role of the ATP-binding domain of HSP70 in ... ATP-binding domain of HSP70,rather than the peptide-binding domain, was essential for these observedHSP functions. Taken together, our results provide evidence supporting the role of HSP70 in the ... transfectedC2C12 cells. Furthermore, there was no direct interac-tion between HSP70 and Smac proteins, and the ATP-binding domain of HSP70, rather than the pep-tide-binding domain, was essential for...
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Báo cáo khoa học: Dissecting the role of the N-terminal metal-binding domains in activating the yeast copper ATPase in vivo pptx
... for the Wilson pro-tein, the N-terminus interacts with another domain of Ccc2 (the catalytic loop for example) and this interac-tion inhibits the ATPase activity. Truncation of the N-terminus ... This model is described in Fig. 6 and shows step-by-stepcopper transport to the Golgi.First, we hypothesized the presence of inhibitorydomain–domain interactions involving the Ccc2 N-ter-minus, ... DMBDCcc2.A role for M1 and M2 in delivering copper toanother binding site in Ccc2 In the first section of this study, we showed that Mbd1 and Mbd2 (M1 and M2 expressed as independentproteins) were...
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Intelligence Reform After Five Years: The Role of the Director of National Intelligence (DNI) potx
... number of initiatives to increase information sharing and integration. These include a joint duty program that requires service in a position that qualifies as joint duty and the introduction of ... the CIA’s official publication, Studies in Intelligence, set forth a distinctly negative assessment of the work of the ODNI and the changes that resulted from the implementation of the Intelligence ... at best, the roles of the DNI and the ODNI are works in progress. None of the tenures of the first three DNIs lasted for more than two years. The DNI position for some intelligence officials...
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Báo cáo Y học: Chimeric receptor analyses of the interactions of the ectodomains of ErbB-1 with epidermal growth factor and of those of ErbB-4 with neuregulin potx
... ligand are cross-linked to domainsI and III, respectively, of the receptor [19,22]. The b sheet of EGF may bind to domain I of ErbB-1, and the other surface of the ligand binds to domain III of ... group is composed of the ligands that bind to both ErbB-1 and ErbB-4, such asbetacellulin, heparin-binding EGF, and epiregulin. The binding of ligands to the extracellular region of receptors causes ... to the EGF receptor. A deletion in the N-terminal region of domain I impaired the EGF binding of ErbB-1 [21]. The N-terminus of EGF was linked to Tyr101 in domain I by using a covalent cross-linking...
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Tài liệu THE DISCOVERY OF THE SOURCE OF THE NILE docx
... scared by the interminable singing, shouting, bell-jingling, horn-blowing, and other such merry noises of the moving caravan, could be seen disappearing in the distance. Leaving the park, ... of their parents in the same way as in the first instance the parents took care of them. Twins are usually hailed with delight, because they swell the power of the family, though in some instances ... grinding corn, making pottery and baskets, and taking care of the house and the children, besides helping the slaves whilst cultivating, or even tending the cattle sometimes. Now, descending...
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Tài liệu Commodore Barney''''s Young Spies A Boy''''s Story of the Burning of the City of Washington docx
... got the best of two bloomin' Yankees, an' the other is sneakin' in some corner!"There came the sound of hurried footsteps, and then the light of the lantern so far illumined ... to feed the prisoners, including the curs in the hold, and Jerry, Jim and I ate on the deck aft, where I could at the same time keep the pungy in the channel.Jim brought out some of the stores ... uponit, and the only wonder was that the Britishers did not awaken sooner. The noise we made in ascending the stairs seemed to me loud enough to alarm the inmates of the house nearat hand, and, therefore,...
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