... to analyze the effect of these mutants during HIV-1 replication, other studies did not reveal the importance of these IN mutants (K186Q and Q214/216L) for viral nuclear import; rather they appear ... Interestingly, in regions Q and C, sequences of 211KELQKQITK and 236KGPAKLLWK possess high similarity in terms of numbers and position of lysine residues and therefore, we term them proximal tri-lysine ... Diagram of HIV-1 IN domain structure and introduced mutations at the C-terminal domain ofthe protein The position of lysines in two trilysine regionsand introduced mutations are shown at the bottom...
... approach andthe standard posterior approach weeks after implantation of hip endoprostheses [11,36] A weakness of this study is clearly the lack of any randomization ofthe patients which may bias the ... conceived ofthe study, participated in its design and coordination and drafted the manuscript AM participated in the study and analyses ofthe study MSS participated in the design ofthe study and ... among others, although in this case the skin incision was in a different direction (from theposterior edge ofthe trochanter major in the direction ofthe fibers ofthe gluteus maximus; Fig 1) The...
... anomalies within the Makassed General Hopsital ZI, SS and AS analyzed the angiograms andthe patients' medical files AHE and AS discussed the results and prepared the manuscript AHE answered the reviewers' ... http://www.cardiothoracicsurgery.org/content/4/1/58 andthe "eye -and- dot method" [12] Most ofthe selective coronary angiographies were performed by the Judkins (femoral) method, although some were done according to the method of Sones (brachial) ... distribution ofthe LCX artery was normal in all of them The left anterior descending coronary artery in all of them originated from a separate ostium in the left sinus and had a normal distribution The...
... timely diagnosis and treatment Given the complexity ofthe post-operative state andthe limitations of a case report, it is difficult to identify the pathogenesis in our case report The pathophysiologic ... worthy of note that one ofthe four reported cases of PRES was initially misdiagnosed as bilateral posterior cerebral artery infarctions [3] Timely MRI and CT imaging as well as an awareness ofthe ... publication of this case report and any accompanying images A copy ofthe written consent is available for review by the Editor-in-Chief of this journal Page of Acknowledgements The authors are...
... risk- and prognosis stratification We considered the low age andthe low cardiovascular risk profile ofthe patient at the time of acute MI, the absence of symptoms after the event andthe absence ... with prior MI and normal coronary arteries are actually not covered by these guidelines, and there are no other indications on the management of these patients in the literature The estimated ... ence and severity of coronary atherosclerosis would allow insights for the further management of our patient MSCT angiography showed absolutely normal coronary arteriesThe absence of atherosclerosis...
... worked in the communications sector Twenty years later, though the number of men remained unchanged, the number of women rose to 550 000 A similar situation was seen in the wholesale and retail ... 450 000 by 1995 The number of men grew only marginally from 425 000 to 480 000 over the same period In defence, the number of men declined from 225 000 to 200 000, while the number of women rose ... answer: The two decades between 1975 and 1995 brought significant changes in the representation of women in Freedonia's work force, according to the graphs In 1975, for example, some 300 000 men and...
... Rule of law: Assessment ofthe law and order tradition in the country produced by the country-risk rating agency International Country Risk (ICR) Average ofthe months of April and October ofthe ... whatsoever for any consequences of its use The term "country", as used in the context ofthe ADB, refers to a member ofthe ADB and does not imply any view on the part ofthe Institute as to sovereignty ... Overview ofthe Financial Sector and Flow of Funds Analysis 3 The Role of Financial Infrastructure and Efficient Financial Markets 14 The Role of Government as Issuer 24 Conclusion: The Example of...
... is the cut-off value in the Recommendations ofthe American Heart Association [35] andthe trigger for initiation of insulin treatment for ICU patients recommended by the American College of ... results and wrote the manuscript AVB and VG participated in patients' inclusion and follow-up IPR was involved in the analysis of results and writing the manuscript All the authors read and approved ... approved the final version Acknowledgements The authors are very grateful to Edita Lukić, Goran Madžarac and Alen Švigir for their help in the acquisition and arrangement ofthe data Page of Author...
... Profile P Equals the mean ofthe scores recorded mental) of a specific problem they need assistance with and consider the severity of these symptoms over the last week The third item asks the ... ofthe four item scores is calculated and is referred to as the MYMOP2 “profile score” The latest version ofthe MYMOP2 questionnaire (MYMOP2) was used in the present study and comprises another ... Table The MYMOP2 scales of Symptom and Profile showed a moderate negative correlation with the General Wellbeing (GWB) and Energy scales ofthe W-BQ12 The Wellbeing scale ofthe MYMOP2 had a strong...
... qualitative and quantitative analyses, drafted the manuscript, and approved the final manuscript WMN contributed to the conception and design ofthe study and participated in the acquisition of data and ... an understanding ofthe importance of ART adherence This may highlight the strength of adherence education and support efforts within the AMPATH pediatric clinics Much ofthe violence and forcible ... approved by the Institutional Research and Ethics Committee ofthe Moi University School of Medicine and Moi Teaching and Referral Hospital (Eldoret, Kenya) andthe Institutional Review Board of the...
... idea ofthe high prevalence of edema in the more advanced grades of cellulite The lack of specific clinical and laboratory studies hinders research on cyclic edema andthe dissemination of information ... legs at the end ofthe day Participants were asked to weigh themselves using the same weighing scales at around a.m and p.m for three consecutive days They were requested to use the same clothes ... patients andthe other (28%) required other types of treatments Aminaphtone was the first drug of choice but when treatment failed ginkgo biloba was prescribed For the patients treated with the ginkgo...
... case of MZ with mirror-imaging of AC in the literature In this case, we describe the second case of MZ with mirror-imaging of AC and discuss the possible clinical implications First, Helland and ... lack of systematic monitoring and follow-up Therefore, a large percentage of patients with AC are probably undiscovered Mirror images, on the other hand, are present in approximately 25% of MZ Therefore, ... consider that it is mandatory to monitor the counterpart ofthe symptomatic patient with AC as early as possible, irrespective ofthe absence of symptoms Conflict of Interest The authors have declared...
... fossa and excision ofthe arachnoid cyst were then surgically performed A straight median incision was made on the skull via theposterior temporal route The occipital squama was cut off andtheposterior ... posterior edge ofthe foramen magnum andposterior arch ofthe atlas were then fully decompressed, followed by opening the dura mater A blister-like cyst was seen to be located in the pons andposterior ... within the cyst The cyst tightly adhered to the cerebrum, pons and cervical spinal cord The compartments were then separated andtheposterior wall ofthe cyst was excised to break down the cystic...
... craniotomy because ofthe proximity ofthe sinus to the orbit andthe anterior skull base [5] The frequency of bilateral absence ofthe frontal sinus has been reported in 3-4% to 10% of several populations ... reliability between observers and was 0.86 Fig Unilateral absence ofthe frontal sinus; on the right, the absence ofthe frontal sinus, and on the left, the limited aeration ofthe frontal sinus; axial ... sinuses, although there is only one frontal sinus ostium The size ofthe sinus and, therefore, its anatomic relationships also depend upon the extent of pneumatization [11] The extent of pneumatization...
... and VAS was used after the canulation They found a significant reduction in the incidence of pain in the Valsalva group: 18 of 25 (72%) patients, whereas 25 of 25 (100%) experienced pain in the ... Activation of either the cardiopulmonary baroreceptor reflex arc or the sinoaortic baroreceptor reflex arc induces antinociception.9,10 There were few studies for evaluating the efficacy of balloon ... with (2) and (2) observed in the distraction and control groups respectively (p= 0.000) Significant reduction in the incidence and severity of venipuncture pain was also observed in the balloon...
... (46,47) They are synthesized by chondrocytes and FLS These cytokines act in various ways in the pathogenesis of OA such as inhibition of synthesis of type (articular) cartilage and activation of catabolic ... present clinical study we sought to evaluate the comparative efficacy and tolerability of 5-Loxin® and Aflapin® in the treatment of OA ofthe knee Materials and Methods Study materials BE-30 (5-Loxin) ... [31] The pain subscale was the average ofthe first five questions of WOMAC and measured using the NU scale from ('no pain') to 100 ('extreme pain') for each question The stiffness subscale was the...
... occurrence ofthe tumor corresponded exactly one to the other; and (4) there was a more than one year interval between trauma andthe appearance ofthe tumor As regards the pathogenesis of post-traumatic ... time interval between trauma andthe appearance ofthe tumor of at least year, a longer latent period increasing the likelihood of a causal relationship The presence ofthe tumor must be proved histologically ... at the time ofthe trauma demonstrating significant injury andthe follow-up scans demonstrating tumor at the same site4 With the routine use of CT and magnetic resonance imaging (MRI), some of...
... Following the suggestions of scientific literature on the advantages ofthe compactness, reliability, ease of use and affordability ofthe 980 nm Diode Lasers, we evaluated the efficacy and safety of ... are reduced [17,18] The lasers normally adopted offer the enormous advantage of being conveyed in a fibre, which serves as the working tip at the end ofthe handpiece The use of flexible, length-adjustable ... question the efficacy ofthe 980nm Laser for photosclerosis of lesions and areas with little melanin and hemoglobin pigmentation [7] Furthermore, to avoid exaggerated fluences and thermal damage to the...
... in the morning and two in the evening for a daily dose of 1500 mg glucosamine and 1200 mg chondroitin Removal of Patients from Therapy or Assessment The criteria for removal of patients from the ... is the most common form of arthritis, and it is often associated with significant disability and an impaired quality of life Clinical and radiographic surveys have found that the prevalence of ... and blood measures of OA ofthe knee compared to G+C It was hypothesized that UC-II would reduce symptoms of OA ofthe knee to a greater extent than G+C A meta-analysis of 20 randomized control...
... Marian AJ Effects of PPARα, γ and δ haplotypes on plasma levels of lipids and progression of coronary atherosclerosis and response to statin therapy in the lipoprotein coronary atherosclerosis study ... gene counting and compared using the ²אtest The data was analysed using SPSS 12.0 software The association between the +294T/C polymorphism and serum lipids, coronary heart disease, and body mass ... for age, smoking, and BMI where appropriate Results The frequency ofthe C-allele was 0.24 andthe genotypes were distributed according to the Hardy Weinberg Equilibrium Overall the C allele frequency...