animal models and theoretical perspectives
Báo cáo khoa học: Synthesis and function of ribosomal proteins – fading models and new perspectives pptx
... for proteins involved in cell proliferation (MIF and cenpA), survival (i.e survivin, BI-1, and dad1), and ribosome biogenesis (members of the small and large ribosomal subunits) Interestingly, not ... RPs in human pathologies and animal models Ribosome deficiencies due to mutations in the genes coding for RPs or for rRNA have been known for many years in Drosophila and Xenopus [59–61] In both ... RP involved Vertebrate animal models for RP deficiency are summarized in Table Conclusions In the last few years, the study of the synthesis and function of RPs has both expanded our knowledge FEBS...
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Báo cáo y học: "Cartilage-specific autoimmunity in animal models and clinical aspects in patients – focus on relapsing polychondritis" ppsx
... response in RA Animal models for RP have been described as those immunized with either collagen type II (CII) or matrilin-1 and as models that appear spontaneously [1–3] These models differ in ... arthritis models and spontaneous models Several other models for arthritis have been reported but these will not be discussed here We believe that they should be considered as alternative models ... terms of genotype and phenotype to RA might help us to highlight some pathways of common importance in the two diseases Animal models of both RP and RA have been reproduced and are now powerful...
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Báo cáo sinh học: " Equivalence of multibreed animal models and hierarchical Bayes analysis for maternally influenced traits" potx
... Institute, New Zealand, and consists of 3749 weaning weight records and the corresponding genealogy (Table 1) Records were collected between 1973 and 1990 on both purebred and crossbred individuals, ... an animal model with maternal effects J Anim Sci 2003, 81:101-108 doi:10.1186/1297-9686-42-20 Cite this article as: Munilla Leguizamón and Cantet: Equivalence of multibreed animal models and ... extended to correlated traits as presented by Cantet and Fernando [2] We will use subscripts “o“ and “m“ to differentiate between direct and maternal effects, respectively Then, using the approach...
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Tài liệu MENTAL DISORDERS - THEORETICAL AND EMPIRICAL PERSPECTIVES docx
... Disorders - Theoretical and Empirical Perspectives an international and multicultural array of experts provide cutting edge empirical and theoretical contributions to the scientific understanding ... orders@intechopen.com Mental Disorders - Theoretical and Empirical Perspectives, Edited by Robert Woolfolk and Lesley Allen p cm ISBN 978-953-51-0919-8 free online editions of InTech Books and Journals can be found ... Kane and al [4], and the development in this period of several explicit criteria defining treatment-resistant schizophrenia (TRS), like those of Kane [4], Dencker and al [5] and Brenner and al...
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Tài liệu MENTAL DISORDERS THEORETICAL AND EMPIRICAL PERSPECTIVES pptx
... orders@intechopen.com Mental Disorders - Theoretical and Empirical Perspectives, Edited by Robert Woolfolk and Lesley Allen p cm ISBN 978-953-51-0919-8 free online editions of InTech Books and Journals can be found ... Theoretical and Empirical Perspectives an international and multicultural array of experts provide cutting edge empirical and theoretical contributions to the scientific understanding of psychopathology ... Kane and al [4], and the development in this period of several explicit criteria defining treatment-resistant schizophrenia (TRS), like those of Kane [4], Dencker and al [5] and Brenner and al...
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Mental Disorders - Theoretical and Empirical Perspectives Edited by Robert Woolfolk and Lesley Allen pptx
... orders@intechopen.com Mental Disorders - Theoretical and Empirical Perspectives, Edited by Robert Woolfolk and Lesley Allen p cm ISBN 978-953-51-0919-8 free online editions of InTech Books and Journals can be found ... Theoretical and Empirical Perspectives an international and multicultural array of experts provide cutting edge empirical and theoretical contributions to the scientific understanding of psychopathology ... Kane and al [4], and the development in this period of several explicit criteria defining treatment-resistant schizophrenia (TRS), like those of Kane [4], Dencker and al [5] and Brenner and al...
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Báo cáo khoa học: Recent insights into cerebral cavernous malformations: animal models of CCM and the human phenotype pptx
... and lesion biology By exploring the function of the CCM genes in animal models this gap is being CCM animal models bridged Animal models have demonstrated the central importance of endothelial ... other animal models are relevant to disease to the degree that they help us further understand the human phenotype Recent investigations have further refined our understanding of this phenotype, and ... are denoted (a) and (b) C elegans, Caenorhabditis elegans CCM animal models genes are found not only in mammals, fish and other vertebrates, but are also found in much more simple and primitive...
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Báo cáo khoa học: "Parsing with Treebank Grammars: Empirical Bounds, Theoretical Models, and the Structure of the Penn Treebank" ppt
... Bottom-Up Models In the remainder of the paper we provide simple models that nevertheless accurately capture the varying magnitudes and exponents seen for different grammar encodings and tree ... magnitudes and exponents 4.4 Traversals Now that we have models for active and passive edges, we can combine them to model traversal counts as well We assume that the chance for a passive edge and an ... issues at hand Figures (a) and (b) show the traversal curves corresponding to the times in figure The interesting cause of the varying exponents comes from the “constant” terms in the theoretical...
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Báo cáo y học: " Epitope spreading in animal models: array of hope in rheumatoid arthritis and multiple sclerosis" pot
... Therapy Vol 10 No Lundberg and Venables reported in one previous study of collagen-induced arthritis [5], though other studies have found equal binding to both citrullinated and arginine-containing ... citrullinated antigens associated with the anti-CCP response and the requirement for specific MHC alleles, the use of transgenic animals could go a long way to analyse the autoimmune response ... JL, Steinman L, Robinson WH: Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination Arthritis Res Ther 2008, 10:R119 Kinloch A, Lundberg K, Venables...
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Báo cáo sinh học: "Estimating variances and covariances for bivariate animal models using scaling and transformation" pot
... with and var(e l ) l and var(e I and e and e are uncorrelated, and the ) e Q ’;1 fixed effects #i and (3 have no elements in common, and the random effects u , i 2 l , l u e and e normally distributed ... extended to fit these and other models, by the introduction of scaling and transformation models The models considered included those for bivariate traits when different fixed effect models are appropriate ... vectors Yl and y are of length n and n and matrices X X Z and Z are of size n t n x m and n x m Our 2 , x, l2 i x n t ,, l2l motivation was a case when a trait Yl was measured on males and y was...
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Báo cáo sinh học: "Inequality of maximum a posteriori estimators with equivalent sire and animal models for threshold traits" pps
... !i)/!! and or the 0’ error standard deviation (sire model) environmental standard deviation (animal model) For the heritability value of 0.20 the estimators from the sire model and the animal ... scale of the progenies and 2, and v and v represent the additive genetic effects of their sires and = Under these conditions v is a priori normally distributed with mean and variance-covariance ... use of equivalent sire and animal models for the underlying variable and the use of the same estimation method lead to different estimators may be counterintuitive Under the animal model the maximum...
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Báo cáo y học: " Characterization of protein tyrosine phosphatase H1 knockout mice in animal models of local and systemic inflammation" docx
... light phase and animals were allowed 1-hour habituation to the test room, if different from the holding room, before testing Testing sequence was randomized between KO and WT animals, and all apparatus ... MCP-1 and IL10 between WT and KO LPS-treated animals Both WT and KO mice displayed a LPS-induced increase in TNFα, MCP-1 and IL10; IL6 level was significantly increased by LPS in both WT and KO ... injection Genotype-related difference in MCP-1 and IL10 between WT and KO LPS-treated animals WT animals displayed a LPS-induced increase in IL10 and IL6; dot line indicates the detection limit...
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Báo cáo khoa học: "Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group" doc
... clinical use Animal models of ARF We fully adopt the general recommendations, outlined by Piper and colleagues [27], in planning, conducting and critically evaluating studies utilizing animal models ... summarizes these principles and other guidelines for the use of animal models in the study of ARF Despite their limitations, animal models remain fundamental to improving our understanding of human ARF ... [28-30] There are three basic types of animal models in use for study of ARF: ischemia; toxins and sepsis models; and several subtypes Each has its own advantages and disadvantages, which are summarized...
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Báo cáo y học: "Anti-inflammatory effects of Radix Gentianae Macrophyllae (Qinjiao), Rhizoma Coptidis (Huanglian) and Citri Unshiu Pericarpium (Wenzhou migan) in animal models" doc
... as it inhibits the production of NO and PGE2 in LPS/IFN-γ-stimulated peritoneal macrophages and reduces edema and the amount of infiltrated cells in animal models Abbreviations CMC: carboxymethyl ... contributions KSK and HIR conducted the experiments and data analysis EKP conducted the in vitro experiments KJ and HJJ prepared herbal extracts JHK and HY assisted the in vivo experiments CKH, YBC and CJR ... manner KHU14 (100 μg/ml) inhibited NO and PGE2 production by 27% and 49% respectively In vivo effects of KHU14 on acute inflammation We employed three animal models of acute inflammation to evaluate...
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Báo cáo y học: "New animal models for evolution and development" pdf
... it arose and how each major parasitic lineage and the various life history and developmental strategies radiated requires a combination of phylogenetics, comparative life-cycle data and the need ... the function of cad in the growth zone and in posterior segmentation is ancestral for bilaterians (animals with bilateral symmetry, including both insects and vertebrates) Averof also reported ... on tapeworms and liver flukes To be a successful parasite, the interaction between host and parasite must be finely balanced Parasites have to circumvent the host’s immune response and to adapt...
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Báo cáo sinh học: "Estimating variances and covariances for multivariate animal models by restricted maximum likelihood" pot
... number of animals), as the only random effects in the model, ie r = and s q(q + 1) Assume effects are ordered i according to traits within animals, and let a be the subvector for the ith animal ... search Such models, which also all information on relationships between animals are usually referred incorporate to as animal models (AM) The derivative-free approach provides a flexible and powerful ... loglal and are constants and not need to be evaluated As above, (9) and (10) also apply, with an appropriate logIDI modification fo T if a second random effect, m, is fitted for each animal ,...
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A study of chinese stock market empirical and theoretical explorations by bayesian and GARCH models
... Conditional Standard Deviations for ΔSHH t and ΔSPt 73 Figure 2.5: Conditional correlation between series ΔSHH t and ΔSPt 74 Figure 2.6: Conditional Standard Deviations for ΔSHH t and 78 ΔHS t ... financial markets Due to economic and geographical considerations, US and Hong Kong are closest stock markets to China, thus understanding the integration between China and these two markets could ... Literature review and motivations 52 2.3 Data and Methodology 57 2.4 Empirical Results 67 2.5 Summary remark for Chapter 82 Chapter 3: A remedy to the flaw of GARCH and Applications to China’s and US Markets...
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Food, Animal production and Human Comsumption in the Asian Region
... Cambodia • Lao PDR • Thailand • Vietnam 33 Land and population Population Density Population Land area Cambodia 15,416,429 181,035 85 Lao PDR 6,834,345 236.800 29 Thailand 63,723,953 513,000 124 ... group and country 1980 and 2005 FAO (2009) 15 Meat consumption and share of net imports in consumption, least-developed countries, 1961–2005 FAO 2009 16 Meat consumption by region, 2000 and 2050 ... its human population with out destroying the enviroment and depleting natural resources???” Land used by region and country group, 1961,1991 and 2007, (FAO, 2009) Food security The World Food Summit...
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Oxo-biodegradable Polymers Present Status and Future Perspectives
... Haines, J.R and Alexander, M (1974) Appl Environ Microbiol., 28, 1084–1085 Heat, D.J., Lewis, C.A., and Rowland, S.J (1997) Org Geochem., 26, 769–785 Albertsson, A.-C., Andersson, S.O., and Karlsson, ... recognized from absorption bands between 3400 and 3200 cm−1 and absorptions in the carbonyl region – specifically between 1780 and 1700 cm−1 – are used to evaluate the rate and extent of the oxidative ... abiotic and biotic, in the degradation mechanism of oxo-biodegradable plastic materials has recently led to the preparation and approval of ASTM D6954-04 “Standard guide for exposing and testing...
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Confirmations, surprises and theoretical reconstructions
... adjudication and con®rmation rarely bears directly on the adequacy of broader theoretical perspectives, the cumulative effect of such research can contribute to the erosion of some perspectives and the ... expertise and autonomy This implies a broad decline of the working class and purely supervisory employees, an increase of the ``relative surplus population,'' and an expansion of experts and proper ... disorganized and atomized at the point of production, and is formed as a collective category primarily within the sphere of consumption, especially in terms of standards of living and the character...
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