and anti inflammatory cytokines in bronchoalveolar lavage t cells of stable lung transplant patients
Báo cáo y học: " Smoking status and anti-inflammatory macrophages in bronchoalveolar lavage and induced sputum in COPD" doc
... show whether anti- inflammatory treatment contributes to the anti- inflammatory macrophage phenotype in vivo, and whether this contributes to treatment effects on inflammation and clinical outcomes ... anti- inflammatory characteristics that may be involved in suppressing inflammation in this area of the lung Our study, as well as recent data from others [19,40], suggest that the anti- inflammatory environment ... are in line with this We hypothesize that a shift in macrophage phenotype contributes to further clinical effects of smoking cessation Therefore, the plasticity of the macrophage phenotype and the...
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Báo cáo y học: " Cofilin activation in peripheral CD4 T cells of HIV-1 infected patients: a pilot study" ppt
... HIV-1-infected patients, confirming the upregulation of cofilin activity in resting CD4 T cells of HIV-1-infected patients Given the great extent of cofilin activation and the fact that a majority ... gp120 Activation of cofilin in resting CD4 T cells cultured in vitro Activation of cofilin in resting CD4 T cells cultured in vitro and stimulated with HIV-1 and gp120 Resting CD4 T cells were ... resting CD4 T cells of HIV-1-infected patients, considering that these resting T cells are chronically exposed to gp120 during the course of infection, and that even in patients on HAART, latently...
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báo cáo hóa học: " Increased levels of HMGB1 and pro-inflammatory cytokines in children with febrile seizures" pot
... also higher in patients without a family history of febrile seizures than in patients with family history These findings may reflect compensatory activation of anti- inflammatory or anti- convulsive ... epileptogenic brain tissue, supporting the suggestion that neuroinflammation may contribute to epileptogenesis in the developing brain In order to determine whether active inflammation, including ... other hand, intranasal administration of IL-6 in adult rats exacerbated the severity of seizures induced by pentylenetetrazole, supporting a pro-convulsant effect [47] In our patients including...
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Báo cáo hóa học: "Clinically important improvement in the WOMAC and predictor factors for response to non-specific non-steroidal anti-inflammatory drugs in osteoarthritic patients: a prospective study" docx
... be interesting to adopt and individualize the treatment of patients who are, at present, less likely to respond and to emphasize the therapeutic patient education especially in patients with ... better ability to discriminate between responders and non-responders than the other two models In fact, to ask the patient about a health transition is simple and intuitive, and patients with ... the effects of a particular intervention In fact, the ability of an instrument to detect such a small difference is essential in order to quantify the minimal difference that patients and their...
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Báo cáo khoa học: " The Antinociceptive and Anti-inflammatory Effect of Ethylacetate Extracts from Bang-Poong (Radix ledebouriellae) on the Freund’s Adjuvant-Induced Arthritis in Rats" pot
... expression by the treatment of BP in this study suggested that the antinociceptive effect of BP on adjuvantinduced arthritis in rats To investigate the anti- inflammatory effect of genus Radix ... expression in SDH and NP (E) In contrast to this, BPH did not inhibit these arthritis-related changes (C and F ) The Antinociceptive and Anti- inflammatory Effect of Ethylacetate Extracts from Bang-Poong ... on the Freund’s Adjuvant-Induced Arthritis in Rats 349 It was reported that several extracts of oriental herbal medicines including radix of Aralia continentalis inhibits interleukin-8 induction...
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Báo cáo y học: "Altered expression of inflammatory cytokines in primary osteoarthritis by human T lymphotropic virus type I retrovirus infection: a cross-sectional study" pps
... Results C-PTHrP in sera and SF To investigate whether a distinct pathological state exists in HTLV-I-infected arthritis, we measured the concentrations of several inflammatory cytokines in SF ... concentrations of several inflammatory cytokines in SF between HTLV-I carrier patients and HTLV-I-negative OA patients By investigating OA patients only and excluding those with RA, we were able to ... area of the tissue; +, patchy staining involving several areas; ++, moderate diffuse staining OST, osteotomy; SYV, synovectomy; TA, total joint arthroplasty Of the cytokines examined in our study,...
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Báo cáo y học: "Biology of recently discovered cytokines: Discerning the pro- and anti-inflammatory properties of interleukin-27" pptx
... Jak1, STAT1, STAT3 and STAT5 in NK cells [6,40]; STAT1 and STAT3 in monocytes [34] and STAT3 in mast cells [34] Together with the limited distribution of WSX-1, the ability to activate Jak/STAT signaling ... that this cytokine is critical in the regulation of both innate and adaptive elements of parasite induced immunity Conclusion Initial studies indicated that IL-27, like IL-12, can promote T and ... directly regulate the kinetics and intensity of protective type II immunity through the suppression of helminth induced Th2 responses 230 While these in vivo studies support the hypothesis that...
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Báo cáo y học: "The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis" pps
... cytokines and/ or MMPs or indirectly due to cytokine-mediated inhibition of the production of growth factors [16] The majority of studies of the regulation of cytokines and destructive enzymes in ... begun to attract interest in OA also Imaging studies have demonstrated synovitis in both early and late OA [34-36], even in joints in The first major finding from this study is that OA cultures of ... neutralising anti- IL-1β antibody, excess Enbrel, or both of these anti- cytokine strategies There was effective neutralisation of TNF-α and IL-1β in cultures treated with Enbrel and the neutralising...
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Báo cáo y học: "Effect of methotrexate and anti-TNF on Epstein-Barr virus T-cell response and viral load in patients with rheumatoid arthritis or spondylarthropathies" ppt
... IFNγ-producing T cells after months (week 12) of MTX or anti- TNF treatment Forty patients (21 SpA and 19 RA) received anti- TNF drugs All RA patients and 10/21 SpA patients had anti- TNF + MTX Twenty-two ... effect of MTX and anti- TNF drug on EBV-specific T- cell effector functions in patients with RA or SpA At 3month follow-up, neither MTX treatment in RA patients nor anti- TNF therapy in RA and/ or ... contributed to interpretation of the data Competing interests The authors declare that they have no competing interests Page of (page number not for citation purposes) Acknowledgements The set of EBV...
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Báo cáo y học: "CD8+ T lymphocytes in bronchoalveolar lavage in idiopathic pulmonary fibrosis" ppt
... involved in the drafting of the manuscript and critical interpretation of all data CS performed part of the statistical analysis JME has made substantial contributions to conception and design of the ... pathogenetic theories in IPF sustain progress despite paucity of interstitial inflammation, the role of inflammatory response in the modulation of tissue injury and fibrosis still remains under investigation ... ratio with breathlessness and physiological indices, in IPF patients Patients and Methods Patients Twenty-seven patients with IPF were included in the study Seventeen (65%) were male, and the mean...
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Báo cáo y học: "Altered expression of T cell Immunoglobulin-Mucin (TIM) molecules in bronchoalveolar lavage CD4+ T cells in sarcoidosis" docx
... in the lungs of patients with Löfgren's syndrome and those without The triggering event is the presentation of an (unknown) antigen by antigen-presenting cells (APC) to T cells In the lungs of ... expression in BALF CD4+ T cells of patients, we also analyzed the levels of galectin-9 in these cells and found that the expression of galectin-9 in BALF CD4+ cells from patients was similar to that in ... suggesting that TIM-1 controls critical regulatory pathways in the immune system Studies on mice have indicated that TIM1 is involved in T helper cell differentiation and suggested that the protein...
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Báo cáo y học: "Dynamics of pro-inflammatory and anti-inflammatory cytokine release during acute inflammation in chronic obstructive pulmonary disease: an ex vivo study" pps
... Due to the nature of COPD exacerbations it is technically difficult to investigate the kinetics of acute inflammatory events within the lung following admission of patients to hospital In this ... explants from patients with characterised COPD and individuals with normal lung function to investigate the kinetics of the acute inflammatory cytokine response within the distal lung towards ... Indeed the activation and infiltration of inflammatory cells including (CD8+) T lymphocytes, macrophages and neutrophils is a prominent feature of COPD[4,5] In addition to the chronic state of...
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Báo cáo khoa học: "Endotoxin neutralization and anti-inflammatory effects of tobramycin and ceftazidime in porcine endotoxin shock" ppt
... immediate cytokine response This indicates that there is no in vivo neutralization of endotoxin-induced cytokine production, and consequently that there is no interaction with binding to LBP or the ... after the start of the experiment At the interim analysis, it was concluded that intersubject variation was not greater than expected and that addition of further animals would not change the ... tobramycin binding that neutralizes the endotoxin effect in vivo cannot be excluded Inhibition of the binding of endotoxin to lipopolysaccharide-binding protein (LBP), which is the most important carrier...
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Báo cáo y học: "Relationship between Anti-CCP Antibodies and Oxidant and Anti-Oxidant Activity in Patients with Rheumatoid Arthrit"
... serum and synovial fluid oxidant and anti- oxidant activity in patients with RA has not been elucidated in the previous studies In this study we aimed to investigate the effect of anti- CCP antibodies ... essential part of the antigenic determinant in these antigens, is post-translationally generated by peptidyl arginine deiminases (PAD) [22] Some reults in the literature also suggest that anti- CCP ... treatment with only NSAID at the study time included in the study Those who had been receiving corticosteroid agents and under treatment with disease modifying anti- rheumatic drugs and anti- TNF...
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Role of Non-Steroidal Anti-Inflammatory Drugs in Gynecology potx
... administration of antenatal indomethacin within 72 hours prior to delivery in premature infants Necrotizing enteroclitis with administration of antenatal indomethacin in premature infants.This ... clotting) as the ratio of prostaglandin E2 to F2 and the ratio of prostacyclin (prostaglandin I2) to thromboxane are elevated [8] These substances are present both in the endometrium and myometrium, ... leukomalacia and administration of antenatal indomethacin in premature infants [29] In addition, the same study showed a statistically significant association between necrotizing enterocolitis and administration...
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báo cáo hóa học: " Inhibition of secreted phospholipase A2 by neuron survival and anti-inflammatory peptide CHEC-9" docx
... results in anti- inflammatory and neuron survival effects that last for at least days, an effect due in part to an interruption of the inflammatory cascade that follows damage to the CNS Given the ... substrate solution to the sPLA2 containing samples Kinetic parameters including the properties of CHEC-9 were determined by measuring the initial velocities (Vo) of enzyme reactions (within minutes ... determined effects of varying the enzyme concentration on CHEC-9 inhibition We wanted to test the proposition that increasing the level of enzyme in the reaction, with a fixed substrate concentration,...
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báo cáo hóa học: " Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway" doc
... 1); TRIF (TIR domain-containing adaptor inducing IFNβ) COMPETING INTERESTS The authors declare that they have no competing interests AUTHOR’S CONTRIBUTIONS LT and HS performed the experiments and ... Activated microglia produce a number of proinflammatory cytokines implicated in neurotoxicity but they also are a major source of anti- inflammatory cytokines, antiviral proteins and growth factors ... alone They show that the PI3K/Akt pathway is involved in LPS- or PIC-mediated induction of anti- inflammatory cytokine genes (IL-10 and IL1ra), but that it had little or no effect on proinflammatory...
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Báo cáo y học: "Decreased effector memory CD45RA+CD62L– CD8+ T cells and increased central memory CD45RA–CD62L+ CD8+ T cells in peripheral blood of rheumatoid arthritis patients" ppt
... effector memory CD8+ T cells in RA may indicate an increase in the migration of these cells into sites of inflammation, and therefore may contribute to ongoing synovial inflammation Competing interests ... differences in the differentiation of T cells in RA patients Decreases in some of the subpopulations in peripheral blood may indicate that there is a selective migration of these cells out of the peripheral ... monoclonal antibody combinations were used to characterize the phenotypes of T cells: anti- CD45RA-FITC /anti- CD3-PE /anti- CD62L-CyChrome/ anti- CD4-APC; and anti- CD45RA-FITC /anti- CD3-PE/antiCD62L-CyChrome /anti- CD8-APC...
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Báo cáo y học: "Association between anti-nucleophosmin and anti-cardiolipin antibodies in (NZW × BXSB)F1 mice and human systemic lupus erythematosus" doc
... 0.002) In contrast, ANA, anti- DNA and anti- β2GPI antibodies rates did not differ significantly between anti- NPM-positive and anti- NPM-negative patients Interestingly, of the 23 anti- NPM-positive ... amplified from the cDNA by PCR with the primers NPM-NdeI (5' -GGAATTCCATATGGAAGATTCGATGGACATGGAC-3', sense) and NPMBamHI (5' -CCGGATCCTTACTTGTCATCGTCGTCCTTGTAGTCCGTACGAAGAGACTTCCTCCACTGCC-3', antisense) ... compared with the Mann-Whitney Utest The percentages of different antibodies in the sera of patients with SLE were compared by using a χ2 test The relationship between the titres of different antibodies...
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Báo cáo y học: "The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus" ppt
... due to a number of factors, including the longevity of the injected protein and the level of free G-actin in the circulation at sites of inflammation inhibiting the DNase I activity Our data obtained ... resistance to the natural inhibitors of DNase I and having increased activity, can provide some protective effect against the development of autoantibodies in mice However, the reduction in the autoantibody ... immunogenicity of these DNA complexes is thought to be central to the pathogenesis of SLE Thus, we felt that it was important initially to demonstrate increased consumption of these complexes in vivo in...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008