... intend to explore these parameters in detail Second, we plan to appreciably enhance the integrated model It appears from both our initial data analysis, as well as our qualitative examination ofthe ... We also extend these models toa new task domain that can elaborate on referential patterns inthe presence of various forms of shared visual information Finally, we make use ofa corpus gathered ... may benefit from a datadriven modelof how collaborative pairs adapt their language inthe presence (or absence) of shared visual information A successful computational modelof referring behavior...
... damaging tissue and releasing pro -in ammatory agents Activated eosinophils, neutrophils, macrophages and lymphocytes increase in number at sites ofin ammation and each are capable of modifying ... cell lysates (data not shown) are capable of binding tothe cytoplasmic domain ofthe siglec-10 protein The binding of SHP-1, however, was missing from the Y667F mutant indicating this to be the ... Hanasaki, K., Varki, A. , Stamenkovic, I & Bevilacqua, M.P (1994) Cytokine-induced beta-galactoside alpha-2,6-sialyltransferase in human endothelial cells mediates alpha-2,6-sialylation of adhesion...
... expectation operator conditional on information available at the beginning of period The life of individuals consists of two parts.1 During initial J1 years they participate inthe labor market ... default (known a priori with certainty at the aggregate level), and all of them insure fully against that risk by paying the appropriate premium tothe bank, the spread will also contain the ... decrease ofthe deposit rate deter individuals from savings The aggregate value of deposits, and hence capital, is falling, which leads to an increase ofthe market rate As regards the lending rate,...
... of data packets each capable of transmitting to 1023 bytes of data Data0 Data1 Data packets have the following format Sync PID Data CRC16 EOP Handshake Packets There are three type of handshake ... containing the control data to be sent, a stall packet indicating the endpoint has had a error or a NAK packet indicating tothe host that the endpoint is working, but temporary has no data to ... packet types Token packets indicate the type of transaction to follow, data packets contain the payload, handshake packets are used for acknowledging data or reporting errors and start of frame...
... C-NodeA> case-mark(C-Nodea) or, ii) C-NodeA - head(Chain) * ease-mark(C-Nodea) In an argument Chain, , theta-mark(C-Node0) In describing the representation ofa Chain, we have drawn ... relevant features (such as L-marking, Case, and 0) If we adhere tothe representational paradigm used above, we can define Chains inthe following manner: Chain Schevaa Node: C-Node: {Cat,Level,Pos,ID,Ftrs} ... chains for lexical antecedents, and attempts to append traces to existing chains This operation must in turn satisfy the chain_view relation, to ensure the added link obeys the relevant grammatical...
... people living in an area stretching from the Arctic Ocean inthe north and the Mediterranean Sea inthe south and from the Atlantic Ocean inthe west tothe Pacific Ocean inthe east The European programme ... the advantages ofa social modelof health The past Protecting children’s health ina changing environment few years have seen an increased commitment to direct tackling ofthe social determinants ... Regional Priority Goal Ensuring public health by improving access to safe water and sanitation i will take advantage ofthe approach and provisions ofthe Protocol on Water and Health3 as a We rationale...
... protein standards, internal controls and blanks were always assayed at the same time and inthe same way All samples were always determined in triplicate and ina blind fashion Immunoblot analysis ... each mouse eats 4–5 mg chow/day, the estimated average vitamin E intake for each animal was ~8–10 I.U./day Assuming that each mouse drinks to mL water/day, the estimated daily intake of GFAP/Actin ... occurs Inflammatory mechanisms are also operative inthe AD brain and significantly contribute tothe pathophysiology ofthe disease Although classical defined inflammation, including such features...
... apoptosis as well as the ability of intra-articular TRAIL gene transfer to induce synovial apoptosis suggest that intra-articular injection of rTRAIL also might be able to induce apoptosis of hyperplastic ... synovium In this report, we have examined the ability of rTRAIL to induce synovial apoptosis in vivo in inflamed rabbit knee joints following intra-articular injection Similar tothe effects of intra-articular ... intra-articular injection of Ad-TRAIL, injection of exogenous rTRAIL was able to induce synovial apoptosis in arthritic joints of rabbits as well as reduce inflammation In addition, there was no adverse...
... decrease in PRG4 in early OA could have a role inthe pathogenesis of cartilage degeneration Inthe present study we have demonstrated in an animal model that early degeneration of cartilage was associated ... indentation testing, which requires repeated saline lavage and swabbing ofthe cartilage surface After ovine lateral meniscectomy, there was a decrease in PRG4 immunostaining with a marked loss of PRG4-positive ... pathways are present in OA, and the inflammatory cytokine IL-1 seems to be one ofthe most influential factors, demonstrating deleterious effects for cartilage in vitro and in vivo, acting to inhibit...
... principal function of IL-10 appears to be anti-inflammatory, limiting and eventually terminating inflammatory responses by inhibiting synthesis of monocyte and macrophage derived pro-inflammatory ... measure of inflammation To test and compare the ability of hIL-10, vIL-10, and mut.hIL-10 to inhibit inflammation inthe inflamed rabbit knees, the number of leukocytes inthe lavage fluids at ... end of this incubation, the media was recovered and stored at -20°C Unincorporated 35SO42- from media was chromatographically separated using PD-10 columns (Phar- macia, Piscataway, NJ, USA), and...
... TGGCTGTTTCTGGCTGTTACTG and AATCAGCAGCGACTCCTTTTCC; IL-4, CCAGCTAGTTGTCATCCTGCTCTTCTTTCTCG and CAGTGATGAGGACTTGGACTCATTCATGGTGC; β-actin, TGTGATGGTGGGAATGGGTCAG and TTTGATGTCACGCACGATTTCC Statistical analysis ... Shizuoka Laboratory Animal Center (Shizuoka, Japan) All mice were maintained ina pathogen-free facility at the Hyogo College of Medicine Animal experiments were done in accordance with the guidelines ... 164:6067-6074 Kuroiwa T, Kakishita E, Hamano T, Kataoka Y, Seto Y, Iwata N, Kaneda Y, Matsumoto K, Nakamura T, Ueki T, et al.: Hepatocyte growth factor ameliorates acute graft-versus-host disease and promotes...
... Los Banos: International Rice Research Institute; 2006:369-389 Adachi Y, Ono E, Miyagawa S: Expansion of Lowland Paddy Field Areas inthe Plain Region of Laos Geographical Review of Japan (Ser.B) ... Watanabe H, Abe K, Hoshikawa T, Prachaiyo B, Sahunalu P, Khemnark C: On trees in paddy fields in Northeast Thailand Southeast Asian Studies 1990, 28:45-54 Kosaka Y, Takeda S, Prixar S, Sithirajvongasa ... Miyagawa et al Journal of Ethnobiology and Ethnomedicine 2011, 7:24 http://www.ethnobiomed.com/content/7/1/24 Page ofInthe plain areas of Laos as well as in Northeast Thailand, which is adjacent...
... interpreted the data and revised the manuscript; CBi interpreted the data and wrote the manuscript All authors read and approved the final manuscript Competing interests The authors declare that they have ... treated with either allanxanthone C or macluraxanthone according tothe same protocol as before No lethality was observed in these two groups of animals, suggesting an absence of toxicity ofthe ... Guttiferaes are capable ofin vivo antileukemic effects ina xenograft murine modelof human CLL These therapeutic activities ofthe natural compounds, of similar extent, occur without apparent toxicity...
... neurovascular examination was normal Plain radiographs showed a displaced fracture at the proximal metaphyseal-diaphyseal junction ofthe left humerus and ipsilateral displaced extension type supracondylar ... the combination of ipsilateral fracture ofthe elbow and forearm Gausepohl et al [7] reported a case with fracture dislocation ofthe elbow combined with unstable distal forearm fracture ofthe ... reduction ofthe supracondylar humerus fracture ina “floating arm” injury like in our case A temporary Kirschner wire allows the surgeon to stabilize the humeral shaft and control the motion in the...
... mice was analyzed for 69 chemokines and cytokines using Luminex-based beadarray L-4F treatment resulted ina trend toward decreased levels of tissue damage and inflammation indicators, including ... Bruin Pharma and Alan M Fogelman is an officer in Bruin Pharma The remaining authors have no competing interests Authors' contributions JW contributed to acquisition of data, performed data analysis ... such as IL-10, a Th2 cytokine involved in B cell activity upregulation and linked to increased IgG anti-dsDNA autoantibodies [55], CCL19, and VCAM-1, indicate increased autoimmune response and increased...
... Page 66 Critical Care 1999, Vol No and anti-inflammatory agents have become the standard of care for reactive airway disease and asthma However, some patients fail to respond to aggressive therapy ... pentobarbital were given to ensure adequate anesthesia (titrated to achieve a heart rate of < 160 beats/min, systolic blood pressure ≤ 140 mmHg, and absence of withdrawal to painful stimuli) Each ... between patients and their response to therapy makes the study ofa single agent during acute, severe bronchospasm difficult to extrapolate tothe clinical setting Studies have shown a variable response...
... extracts ‘Immunoeducation’: a novel strategy or an utopian goal? Bacteria or bacterial products are already being tested against allergic diseases Encouraging preliminary data are coming from animal ... allergic asthma in animal models [29] Adjuvant DNA immunostimulatory sequences can provide part ofthe immunostimulatory effects of Freund’s adjuvant without the severe inflammatory and toxic side ... in those ‘unhygienic’ areas inhale and ingest a different kind, variety and amount of bacteria compared with children of farmers and anthroposophic families, who have access to natural soil and...
... Creatinine clearance (Clearcrea) was assessed as an index ofthe glomerular filtration rate according tothe standard procedure to measure the function ofthe investigated kidney Available online ... withdrawal of blood and continuous infusion of Ringer's lactate at a rate of 15 ml/kg/hour (Baxter, Utrecht, The Netherlands) The body temperature ofthe rat was maintained at 37 ± 0.5°C during the ... Germany) A catheter inthe right carotid artery was connected toa pressure transducer to monitor the arterial blood pressure and the heart rate The right jugular vein was cannulated and the catheter...
... Expression and reactivation of HIV ina chemokine induced modelof HIV latency in primary resting CD4+ T cells Suha Saleh1,2, Fiona Wightman1,2, Saumya Ramanayake1, Marina Alexander3, Nitasha Kumar1,2, ... the cytoplasm The absence of MS RNA inthe cytoplasm could potentially be secondary toa block in nuclear export of viral mRNA or destruction of MS RNA inthe cytoplasm We were unable to distinguish ... safety profiles of drugs such as IL-7 and vorinostat Strategies that activate latent HIV in infected individuals on cART are likely to include combinatorial approaches and our model provides a robust...
... resulting inthe release of various inflammatory mediators which in drive the early phases of allergic reactions In addition, activated mast cells and basophils also produce an array of cytokines and ... ofthe lung parenchyma has significant limitations Characteristic features airway remodelling of human asthma such as intraepithelial recruitment of eosinophils, lamina propria inflammation and ... transferred intratracheally (Hammad et al., 2010) It has been shown that pulmonary immune tolerance rather than airway inflammation can be induced by respiratory administration ofa harmless antigen...