amp 945 2 amp 946 1 integrin leads to rapid internalization of the virus receptor complexes
Báo cáo y học: "Bench-to-bedside review: Biotrauma and modulation of the innate immune response" pps
... applied to injured lungs, causes the release of inflammatory mediators, which may then pass on to the circulation [9 , 21 ,24 ,27 ] The main theory in support for increasing levels of inflammatory mediators ... leading to activation of the 2 receptors on cells of both myeloid and nonmyeloid origin, resulting in the downregulation of proinflammatory cytokines and upregulation of anti-inflammatory mediators ... interests References 10 11 12 13 14 15 16 Conclusion 28 4 The clinical importance of appreciating the role played by innate immunity in VILI goes beyond understanding what we 17 Beutler B: Science...
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Báo cáo y học: " Characterization of the innate immune response to chronic aspiration in a novel rodent model" ppsx
... 20 03, 11 5(Suppl 3A):39S-44S Page 10 of 12 (page number not for citation purposes) Respiratory Research 20 07, 8:87 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 Ducolone A, Vandevenne A, Jouin H, ... Curr Opin Immunol 19 98, 10 (6):607- 613 http://respiratory-research.com/content/8 /1/ 87 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 Wills-Karp M, Luyimbazi J, Xu X, Schofield B, Neben TY, ... dysfunction in patients with gastroesophageal reflux disease Ann Thorac Surg 20 04, 78(4) :11 42- 11 51 discussion 11 42 11 51 Hadjiliadis D, Duane Davis R, Steele MP, Messier RH, Lau CL, Eubanks SS,...
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Báo cáo khoa học: Proteolytic activation and function of the cytokine Spatzle in the innate immune response of a lepidopteran insect, Manduca sexta ppt
... compilation ª 20 09 FEBS C An et al 12 13 14 15 16 17 18 19 20 21 22 23 24 M et al (20 06) A Spatzle-processing enzyme required for toll signaling activation in Drosophila innate immunity Dev Cell 10 , 45–55 ... the clip-domain serine proteinase [ 12 ] Easter cleaves proSpatzle to yield active C106 ¨ [7 ,13 ] C106 then binds to the ectodomain of the transmembrane receptor Toll and thereby initiates a cytoplasmic ... Adaptive evolution of relish, a Drosophila NF-kappaB ⁄ IkappaB protein Genetics 15 4, 12 3 1 12 3 8 FEBS Journal 27 7 (20 10 ) 14 8 1 62 ª 20 09 The Authors Journal compilation ª 20 09 FEBS 16 1 Manduca sexta...
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Báo cáo Y học: Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules pptx
... Method of analysis of PR dimerization Ref 45 >10 0 10 0 Kinetic analysisa Kinetic analysis Kinetic analysis [16 ] [19 ] [20 ] Kinetic Kinetic Kinetic Kinetic Kinetic [20 ] [20 ] [ 21 ] [ 21 ] [ 21 ] 12 0.5 0 .15 ... been likened to that of a Ôright-handÕ [35] The major subdomains of the polymerase domain of p66 are termed fingers (residues 1 85, 11 8 15 5), palm (86 11 7, 15 6 23 7) and thumb (23 8– 318 ) The DNA polymerase ... D64, D 116 and E1 52 The C-terminal domain, residues 22 0 28 8, appears to significantly contribute to DNA binding [64] and is linked to the catalytic core by residues 19 5 22 0, an extension of the final...
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Báo cáo khoa học: The starch-binding capacity of the noncatalytic SBD2 region and the interaction between the N- and C-terminal domains are involved in the modulation of the activity of starch synthase III fromArabidopsis thaliana pdf
... CD+St2 .1 CD+St3.3 CD–D3 0 .28 2. 69 0. 32 0.65 0.59 1. 71 1.76 0.78 1. 05 1. 11 1.87 1. 0 1 .2 0.9 1. 1 0.8 1 .2 0.9 1. 0 1. 3 1. 1 1. 3 ± ± ± ± ± ± ± ± ± ± ± 0.05 0 .16 0. 12 0 .15 0.07 0 . 21 0 .14 0 .13 0.09 0 .10 ... (mgÆmL )1) nH CD+D 12 3 W366A CD+D 12 3 Y394A CD+D 12 3 W366AY394A CD–D 12 3 W366A CD–D 12 3 Y394A CD–D 12 3 W366AY394A 1. 73 0. 32 3.0 1. 55 0 .26 2. 99 1. 0 1 .2 1. 8 0.8 1. 0 1. 1 ± ± ± ± ± ± 0 .10 0 .13 0 .29 0 .11 0.03 0 .23 ... 0. 62 0.59 0. 81 1.74 1. 1 1. 0 1. 1 2. 0 1. 8 1. 1 0.9 1. 8 1. 6 1. 1 1 .2 Vmax (unitsÆmg )1) nH ± ± ± ± ± ± ± ± ± ± ± 0.49 0.05 0 .18 0.54 0 .17 0 .15 0 .13 0 .14 0.03 0.09 0. 12 ± ± ± ± ± ± ± ± ± ± ± 0.3 0.2...
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Báo cáo khoa học: " Cisplatin chemotherapy (without erythropoietin) and risk of life-threatening thromboembolic events in carcinoma of the uterine cervix: the tip of the iceberg? A review of the literature" docx
... Radiation Oncology 20 06, 1: 14 10 11 12 13 14 15 16 17 18 19 20 21 http://www.ro-journal.com/content /1/ 1 /14 Peters WA, et al.: Concurrent chemotherapy and pelvic radiation therapy compared with ... Ann Oncol 20 00, 11 (1) :11 7 -11 8 Otten HM, et al.: Symptomatic venous thromboembolism in cancer patients treated with chemotherapy: an underestimated phenomenon Arch Intern Med 20 04, 16 4 (2) :19 0-4 Dusenbery ... mortality of gynecologic brachytherapy Cancer 19 91, 67 (11 ) :27 86 -27 90 Lanciano R, et al.: Perioperative morbidity of intracavitary gynecologic brachytherapy Int J Radiat Oncol Biol Phys 19 94, 29 (5):969-974...
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Báo cáo y học: "Bench-to-bedside review: Functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis" ppsx
... specific receptor clustering in rafts Eur J Immunol 20 01, 31: 315 3- 316 4 42 Means TK, Golenbock DT, Fenton MJ: The biology of toll-like receptors Cytokine Growth Factor Rev 20 00, 11 : 21 9 -23 2 43 ten Cate ... Med 19 99, 340 :20 7 - 21 4 31 Astiz ME, Rackow EC: Septic shock Lancet 19 98, 3 51: 15 011 505 32 Beutler B, Poltorak A: Sepsis and evolution of the innate immune response Crit Care Med 20 01, 29 (suppl):S2-S6 ... proinflammatory activity [11 0], attenuation of inflammatory cytokine and chemokine generation [23 ], and upregulation of antiapoptotic genes of the Bcl -2 family of homologs [11 1] Endothelial cells...
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Báo cáo y học: "Apoptosis resistance in HIV-1 persistently-infected cells is independent of active viral replication and involves modulation of the apoptotic mitochondrial pathway" pot
... U1 Cells U1 Cells + PMA 14 .07 ± 0. 01 14.08 ± 0. 01 1.06 ± 0.03 1. 05 ± 0.03 14 .14 ± 0.05 12 . 86 ± 0.90 1. 60 ± 0.03 51. 96 ± 9 .20 18 .26 ± 0.80 1 52. 04 ± 1. 50 4 .18 ± 1. 11 1 91. 76 ± 0.48 HIV -1 persistently-infected ... different apoptotic stimuli, including acute human immunodeficiency virus- type (HIV -1) infection British journal of haematology 19 95, 89 (1) :24 -33 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 Mahlknecht ... 20 03 05 -13 787) and University of Buenos Aires (M0 91) to G.A.R References 10 11 12 Benedict CA, Norris PS, Ware CF: To kill or be killed: viral evasion of apoptosis Nature immunology 20 02, 3 (11 ) :10 13 -10 18...
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Báo cáo y học: " Early alterations of the innate and adaptive immune statuses in sepsis according to the type of underlying infection" docx
... of Athens, Medical School, 11 4 Vassilis Sofias Str., 11 527 Athens, Greece Received: December 20 09 Revised: 19 February 20 10 Accepted: 26 May 20 10 Published: 26 May 20 10 13 14 15 16 17 18 19 20 ... SD) 11 .7 ± 6.8 15 .7 ± 8.8 12 . 7 ± 7.7 18 .2 ± 7.5 20 .0 ± 5.4
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Báo cáo sinh học: "∆RR vaccination protects from KA-induced seizures and neuronal loss through ICP10PK-mediated modulation of the neuronal-microglial axis" docx
... from HSV -2( G) were previously described [ 12 1 4 ,16 -18 ,20 , 21 ] Briefly, to construct ∆RR, we took advantage of previous findings that the large subunit of the HSV -2 ribonucleotide reductase (R1, also ... Enemies Within Science 19 98, 28 1( 53 81) :13 12 - 13 16 20 21 22 Carson MJ, Doose JM, Melchior B, Schmid CD, Ploix CC: CNS immune privilege: hiding in plain sight Immunol Rev 20 06, 21 3:48-65 Minghetti L, ... simplex virus Page 13 of 14 (page number not for citation purposes) Genetic Vaccines and Therapy 20 08, 6 :1 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 type large subunit of ribonucleotide...
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Tài liệu Báo cáo khoa học: Modulation of the enzymatic efficiency of ferredoxin-NADP(H) reductase by the amino acid volume around the catalytic site pptx
... 0. 82 25 0 .20 9.97 0. 011 0 .14 0. 018 0.00 2. 86 0.54 4.58 3.07 4 .28 41 22 37 87 29 31 38 31 31 12 0 18 18 ± ± ± ± ± ± 32 42 ± ± ± ± ± ± 22 15 0.5 0.04 0.04 ± ± ± ± ± ± 0.04 0.50 0.003 0. 01 0.0 02 ± ... absence of NADP+ (KdA)b 0.73 3.70 0 .23 4.00 ND ND 5 .16 2. 78 2. 80 2. 74 2. 86 3.53 0.68 1. 02 2.69 2. 20 2. 88 2. 77 ± ± ± ± 0 .19 0.70 0.05 1 .22 ± ± ± ± ± ± 0 .25 0 .20 0.30 0 .24 0 .22 0.39 ± ± ± ± ± ± 0. 02 ... (s )1) kcat ⁄ Km (lM )1 s )1) DDGMUT ⁄ WTb (kcalÆmol )1) Kd(NADP+)c (lM) Kd(NADP+)d (lM) WT C266A L268V C266AL268A C266L C266M ) 21 .5 )25 .0 )96 .2 53 .2 55.5 15 19 3 31 29 9 16 44 374 39 308 3.5 2. 32 0.82...
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Báo cáo khóa học: Collectins Players of the innate immune system docx
... J.P (19 95) Activation of human monocytes by strepto- 11 7 11 8 11 9 12 0 12 1 12 2 12 3 12 4 12 5 12 6 12 7 12 8 12 9 13 0 13 1 1 32 13 3 coccal rhamnose glucose polymers is mediated by CD14 antigen, and mannan ... proteophosphoglycan of 12 4 8 J K van de Wetering et al (Eur J Biochem 27 1) 19 9 20 0 20 1 20 2 20 3 20 4 20 5 20 6 20 7 20 8 20 9 21 0 21 1 21 2 21 3 21 4 Leishmania mexicana amastigotes activates complement by triggering the ... to the allergens of Aspergillus fumigatus and block 18 4 18 5 18 6 18 7 18 8 18 9 19 0 19 1 1 92 19 3 19 4 19 5 19 6 19 7 19 8 allergen-induced histamine release from human basophils Clin Exp Immunol 11 0, 24 1 24 9...
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Báo cáo khoa học: Copper-containing nitrite reductase fromPseudomonas chlororaphis DSM 50135 Evidence for modulation of the rate of intramolecular electron transfer through nitrite binding to the type 2 copper center pot
... DSM 5 013 5 ND, not determined g-values 0.0 01, A-values 0 .1 Cu Az (mT) Cu center gz gy gx T1Cu T2Cu As-puried With NO2 2. 220 2. 0 52 2.036 5.8 2. 350 2. 34 2. 11 0 ND 2. 040 ND 10 .7 12 . 0 ể FEBS 20 04 ... Ni(NO3 )2, 0.03; Na2SeO3, 0.03; CoCl2, 0.6 and Na2B2O7, 0 .1 The optical density, the concentrations of nitrate [17 ] and nitrite [18 ], the pO2 and the pH of the medium were monitored, and the composition ... IAM 10 13: evidence for intramolecular electron transfer from type Cu to type Cu J Am Chem Soc 11 6, 11 14 511 156 Libby, E & Averill, B.A (19 92) Evidence that the type copper centers are the site of...
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Báo cáo khoa học: Signaling events mediating activation of brain ethanolamine plasmalogen hydrolysis by ceramide pot
... Res 22 , 12 2 3– 12 2 9 20 Bligh, E.G & Dyer, W.J (19 59) A rapid method of total lipid extraction and purification Can J Biochem Physiol 39, 911 – 917 21 Surette, M.E., Winkler, J.D., Fonteh, A.N & Chilton, ... 21 3.7 1 32. 9 96.4 20 2.4 14 5.7 22 7.3 ± ± ± ± 26 .3 10 .3* 44.5 10 .3* ± ± ± ± 19 .0 37 .2* 28 .0 21 .9* * P < 0.05 compared with their respective controls Table Effect of endothelin -1 (ET -1) on brain Etn ... 516 7 32 597 383 686 4 72 915 5 13 134 920 9 6354 9884 8364 ± ± ± ± ± ± 10 7 13 9* 85 20 0 14 8 95 ± ± ± ± ± ± 609 29 18 * 16 09 503 11 77 807 * P < 0.05 compared with their respective controls Fig Effect of...
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Báo cáo Y học: Irregular spiking in free calcium concentration in single, human platelets Regulation by modulation of the inositol trisphosphate receptors ppt
... 497, 12 1 P– 12 2 P 22 Tertyshnikova, S & Fein, A (19 97) [Ca2+]i oscillations and [Ca2+]i waves in rat megakaryocytes Cell Calcium 21 , 3 31 344 15 52 R M A van Gorp et al (Eur J Biochem 26 9) 23 O’Rourke, ... Chem 26 7, 25 11 3 25 11 9 41 Bird, G.S.J., Burgess, G.M & Putney, J.W (19 93) Sulfhydryl reagents and cAMP-dependent kinase increase the sensitivity of the inositol 1, 4,5-trisphosphate receptor in ... localization and function of (1, 4,5)IP3 receptor subtypes and the (1, 3,4,5)IP4 receptor GAP1IP4 BP in highly purified human platelet membranes Blood 95, 34 12 3 422 27 Authi, K.S (19 97) Ca2+ homeostasis in...
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Báo cáo khoa học: Modulation of the Arabidopsis KAT1 channel by an activator of protein kinase C in Xenopus laevis oocytes potx
... Journal 27 7 (20 10 ) 23 18 23 28 ª 20 10 The Authors Journal compilation ª 20 10 FEBS 23 25 Phosphorylation of KAT1 channel 26 27 28 29 30 31 32 33 34 35 36 37 38 A Sato et al phosphorylation of the inactivation ... in the regulation of KAT1 channel activity to respond to various FEBS Journal 27 7 (20 10 ) 23 18 23 28 ª 20 10 The Authors Journal compilation ª 20 10 FEBS 23 23 Phosphorylation of KAT1 channel A Sato ... sensitive to PMA-induced PKC activation Even after PMA application, the FEBS Journal 27 7 (20 10 ) 23 18 23 28 ª 20 10 The Authors Journal compilation ª 20 10 FEBS 23 21 Phosphorylation of KAT1 channel A Sato...
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Báo cáo khoa học: Modulation of the endocannabinoid system by focal brain ischemia in the rat is involved in neuroprotection afforded by 17b-estradiol pdf
... [pmolÆmin )1 (mg protein) )1] 820 ± 80 884 ± 90 NAPE-PLD activity [pmolÆmin )1 (mg protein) )1] 22 ± 25 ± CB1 receptor binding [fmolÆ(mg protein) )1] 19 0 ± 20 18 0 ± 20 ER antagonist ICI1 82 780 (0 .25 mgÆkg )1, ... cannabinoid (CB1 and CB2) receptors, non-CB1 ⁄ non-CB2 receptors, and noncannabinoid receptors, including the type vanilloid receptor [transient receptor potential vanilloid -1 (TRPV1)], a ligand-gated ... we assessed the effect of CB1 receptor blockade or activation on ischemic damage We found that administration of the CB1 receptor antagonist SR1 417 16 (3 mgÆkg )1, intraperitoneal), 15 before MCAo,...
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Báo cáo hóa học: " Modulation of the major histocompatibility complex by neural stem cell-derived neurotrophic factors used for regenerative therapy in a rat model of stroke" ppt
... progenitor cells to embryonic stem cells: neural induction and transplantation in a mouse ischemic stroke model J Neurosci Res 20 07, 85 :18 51- 18 62 Page 10 of 10 10 11 12 13 14 15 16 17 18 19 20 21 22 ... (0.36 1. 52 (0.34 1 .22 (0. 51 1. 42 ± 0 .11 (0.58 ± 0 .25 ) 1 .24 ± 0.07 (0.64 ± 0 .15 ) 1. 18 ± 0.04 (0.7 ± 0 .17 ) Sham-operated normal rats (n = 10 ) two were comparable (p > 0.05) From weeks two to four, the ... up-regulation of in vivo NGF synthesis that is augmented by the NSC allograft 1. 83 (0 .22 1. 86 (0 . 21 ± ± ± ± 0.06 0 .11 ) 0 .14 0 .13 ) ± ± ± ± ± ± 0 .25 0.33) 0 .10 0 .16 ) 0.09 0 . 21 ) Histology Animals were sacrificed...
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Báo cáo lâm nghiệp: " A comparison of the photosynthetic radiation response of Scots pine shoots in direct and diffuse radiation" pot
... Smolander H (19 83) Photosynthesis of a Scots pine shoot: the effect of shoot inclination on the photosynthetic response of a shoot subjected to direct radiation !gnc Mefeoro/ 29 , 19 1 -20 6 Smolander ... area (Fig B), the rate of photosynthesis represents the photosyn- photosynthetic units were represented by points within the needles and the irradiance (the photon field strength) at these points ... the needle surface area was simulated In the 2nd case, length of the photon pathway within the needle before reaching the point under consideration the Results a needle In the 2nd approach, the...
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