alterations in myocardial cellular energy and diastolic function a potential role for d ribose
Báo cáo y học: "Identification of possible candidate genes regulating Sjögren''''s syndrome-associated autoimmunity: a potential role for TNFSF4 in autoimmune exocrinopathy" docx
... of age The glands were fixed in 10% formalin, embedded in paraffin, and sectioned and stained with hematoxylin and eosin (H&E) dye Representative H&E-stained histological sections of submandibular ... mice euthanized at 20 or 24 weeks of age The glands were fixed in 10% formalin, embedded in paraffin, and sectioned and stained with hematoxylin and eosin (H&E) dye Representative H&E-stained histological ... read and approved the final manuscript Proposed genetic predisposition for and fatty acid homeostasis/trans6.NOD-Aec1Aec2 in the salivary and lacrimal glands of to lipid depositions mice and...
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Báo cáo khoa học: Mitochondrial affinity for ADP is twofold lower in creatine kinase knock-out muscles Possible role in rescuing cellular energy homeostasis pptx
... mitochondrial membrane to ADP via VDAC porins [21] and the affinities of ANT and F1-ATPase for ADP [22] The latter also introduces a dependence on the mitochondrial membrane potential and thereby ... contamination and no Triton X-100 was added Data analysis and statistics Oxygraph data analysis was performed with high-resolution respirometry software (oroboros datlab 2.1; Innsbruck, Austria) ... that an increase in oxidative capacity and a reduction of the ADP affinity both constitute adaptations of mitochondrial function to alleviate compromised temporal and spatial buffering of the ATP...
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Báo cáo y học: "Carotid intima-media thickness and endothelial function: useful surrogate markers for establishing cardiovascular risk in patients with inflammatory rheumatic disease" pdf
... the development of cardiovascular events in patients with rheumatoid arthritis Semin Arthritis Rheum 2008 [Epub ahead of print] Gonzalez-Juanatey C, Llorca J, Garcia-Porrua C, SanchezAndrade A, ... intima-media thickness and atherosclerosis in rheumatoid arthritis Arthritis Res Ther 2008, 10:102 Gonzalez-Juanatey C, Llorca J, Martin J, Gonzalez-Gay MA: Carotid intima-media thickness predicts ... with inflammatory rheumatic diseases Competing interests The authors declare that they have no competing interests References Veldhuijzen van Zanten JJCS, Kitas GD: Inflammation, carotid intima-media...
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Báo cáo y học: " In vivo imaging of the airway wall in asthma: fibered confocal fluorescence microscopy in relation to histology and lung function" potx
... second; FVC: forced vital capacity; GINA: Global Initiative for Asthma; NHLBI: National Heart, Lung, and Blood Institute; NIAID: National Institute of Allergy and Infectious Diseases; aOCT: anatomical ... Schadewijk A, van der Plas DT, Schot R, van den Aardweg JG, de Jongste JC, Hiemstra PS, Mauad T, Rabe KF, Sterk PJ: Bronchial inflammation and airway responses to deep inspiration in asthma and ... manuscript PJS participated in the design of the study and its coordination, and helped to draft the manuscript PWK conceived the study, participated in its design and coordination, performed all bronchoscopic...
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Tài liệu Mothers’ Investments in Child Health in the U.S. and U.K.: A Comparative Lens on the Immigrant ''Paradox'' docx
... Smoking Around Child Age Age Age Maternal Binge Drinking Age Age Age Frequency of Maternal Smoking Age None < packs/day 5-1 pack/day >1 pack / day Age None < packs/day 5-1 pack/day >1 pack / day ... exams and vocational equivalents; level includes “sub-degree” qualifications and certificates, and level includes university diplomas, teaching and nursing degrees and post-university education ... Table 3: Regression of Maternal Health Behaviors on Generational Status and Race/Ethnicity, FFS and MCS* Prenatal Prenatal Early Prenatal Smoking Drinking Breastfed around Child Binge Drinking...
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Báo cáo " Community based coastal resources management behind changes in surface water environment and land policy: A case study in the Tam Giang Lagoon, Central Vietnam " ppt
... management is a process of governance and political decision-making, geared toward the formation of partnerships and power sharing It is consensus-driven and geared toward achieving a balance of interests ... changes in historical lagoon’s utilization and management We used software tools such as Mapinfo 8.5 and Excel in order to modify maps and reckon the surveyed data And we also used the comparative ... standards applied for coastal ecosystem conservation and aquaculture Moreover, average concentration of total coliform in the lagoon water exceeded the permitted level of Vietnam standard of water...
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WHO Library Cataloguing-in-Publication Data: Gender and tobacco control: a policy brief ppt
... research for almost a century This has resulted in “male” brands and “female” brands, supported by tailored marketing campaigns and imagery that are also often aimed at children and youth Gender-specific ... how gender identity and gendered roles are manipulated by the tobacco industry Specific textual and pictorial health warnings for men and for women reflecting sex and gendered effects and patterns ... Tobacco education and information programmes and materials should be empowering, blame-free and stigma-reducing In particular, improved approaches are needed for programmes that focus on maternal...
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Breast cancer incidence and case fatality among 4.7 million women in relation to social and ethnic background: a population-based cohort study pdf
... LISA is a yearlyupdated nationwide database consisting of data from 1990 and onwards on all individuals 16 years or older registered as living in Sweden [11] We obtained individual information ... social position on breast cancer incidence and case fatality among large and growing immigrant populations and their daughters in Sweden and among native Swedes Materials and methods Database ... TM and OB had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis OB and TM conceived and designed the study...
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Báo cáo hóa học: " Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood" pptx
... that will be required upon hand-off for assay validation SJ, AW, SWA and KA performed the in vitro assays on monkeys treated with Ab-01 and control Ig and analyzed the data, and KA and SA performed ... studies in humans and monkeys that identified the candidate biomarkers, and they participated in the data analyses AAH developed the customized Spotfire tool used for data analyses and reviewed ... included on the custom TLDA for monkey studies were among the "inventoried" assays available from ABI, and are described in Table cDNA synthesis, preparation of samples for TLDA assay and measurements...
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Báo cáo y học: "Fat-Storing Multilocular Cells Expressing CCR5 Increase in the Thymus with Advancing Age: Potential Role for CCR5 Ligands on the Differentiation and Migration of Preadipocytes" pot
... and 21 months of age were mounted in a tissue array as previously described (19) For hematoxylin and eosin staining, sections were deparaffinized in xylene, re-hydrated in graded alcohols and ... alcohol before eosin (Lerner Laboratories, Pittsburgh, PA) staining, dehydrated in graded alcohol and then mounted in organic media For peroxidase immunohistochemistry, a standard two-step Dako ... groups have demonstrated that adipose tissue is able to produce proinflammatory cytokines and fat-derived peptides termed adipokines (including ligands such as adiponectin, leptin, resistin, TNF-α,...
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Báo cáo y học: "Analysis of immunoglobulin light chain rearrangements in the salivary gland and blood of a patient with Sjögren’s syndrome" pptx
... V A1 9 and Jκ2, had a CDR3 of nine amino acids, and shared three replacement mutations (one in CDR1, and two in FR2 each) Finally, two rearrangements from the parotid gland and two from peripheral ... developing parotid gland enlargement, lymphoma of the parotid gland was excluded by partial parotidectomy and histological examination After approval by the local ethics committee and informed consent ... same patient This patient manifested increased titers of autoantibodies (anti-Ro and anti-La), hypergammaglobulinemia and enlargement of the parotid glands, and could therefore be considered...
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Báo cáo y học: "Relationship between physical activity and stiff or painful joints in mid-aged women and older women: a 3-year prospective study" pot
... KCH and YDM participated in the study conception and design, statistical analyses, interpretation of the data, and drafting of the manuscript WJB participated in the study conception, study design, ... Government Department of Health and Aged Care: An Active Way to Better Health: National Physical Activity Guidelines for Adults Canberra: Australian Government Department of Health and Aged Care; 1999 ... of Health and Ageing for funding and to the women who provided the survey data They would also like to thank Melanie Spallek for her statistical guidance and Annette Dobson for her statistical...
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Báo cáo y học: " Media and education play a tremendous role in mounting AIDS awareness among married couples in Bangladesh" potx
... NIPORT (National Institute of population research and Training), Mitra and Associates and ORC Macro In 'Bangladesh Demography and Health Survey 2003–2004' Dhaka and Calverton: NIPORT, Mitra and Associates ... Khan MA, Rahman M, Khanam PA, Khuda BE, Kane TT, Ashraf A: Awareness of sexually transmitted diseases among women and service providers in rural Bangladesh International Journal of STD and AIDS ... monitoring and evaluation regarding AIDS awareness In this regards a few national and international researchers have made attempts to understand the reasons and come up with some explanations...
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báo cáo khoa học: "Gene-expression and network-based analysis reveals a novel role for hsa-mir-9 and drug control over the p38 network in Glioblastoma Multiforme progression" ppsx
... versatility, we can identify targets for sophisticated therapeutics approaches Materials and methods Gene datasets TCGA Data were obtained from The Cancer Genome Atlas (TCGA) database This dataset comprises ... p38-alpha and p38-beta pathway Cis Retinoic Acid RARA Map kinase inactivation of smrt co-repressor Sorafenib RAF1 p38 signaling mediated by MAPKAP kinases Tamoxifen ESR1 Signaling mediated by p38-alpha ... targets Drug name Target Pathway Accutane RARA Map kinase inactivation of smrt co-repressor CCNU STMN4 Signaling mediated by p38-gamma and p38-delta pathway Celebrex COX2 Signaling mediated by p38-alpha...
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Báo cáo y học: "A crucial role for tumor necrosis factor receptor 1 in synovial lining cells and the reticuloendothelial system in mediating experimental arthritis" pps
... study design, statistical and data analysis, interpretation of data, and drafting of the manuscript WBvdB conceived of the study and helped draft the manuscript All authors read and approved the ... (HpNS) (a) Appearance of arthritis in fore and hind paws was monitored at indicated time points and scored for severity (b) Histological analysis of inflammation ('infiltrate' and 'exudate') and proteoglycan ... contributed to the study design, statistical and data analysis, interpretation of data, and drafting of the manuscript SV, BTvdB, and MBB helped to acquire data JG, SA-R, and FAvdL contributed to...
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Báo cáo y học: "Changes in 10-12 year old’s fruit and vegetable intake in Norway from 2001 to 2008 in relation to gender and socioeconomic status - a comparison of two cross-sectional groups" pptx
... times/week among 6th and 7th graders Time Fruit and vegetable intake b Outcome variable: Fruit and vegetable intake Potential moderators: Parental education Gender Figure Model of mediation and moderation ... recontacted in 2008 and invited to once more participate in a similar survey among 6th and 7th graders (cohort II) At that time 27 schools agreed to participate, and all 6th and 7th graders in these ... effect of parental education on the change in FV intake over time SE, standard error All analyses are adjusted for clustering effects and time, gender, parental education and treatment condition...
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Báo cáo sinh học: "Mapping Quantitative Trait Loci (QTL) in sheep. III. QTL for carcass composition traits derived from CT scans and aligned with a meta-assembly for sheep and cattle carcass QTL" pot
... lean meat yield) and weight (hot and cold carcass weight, yearling, weaning and slaughter weight) Single and aggregated bars, heat maps and plots can be selected for sheep and cattle as well as ... overall design, project management, and was involved in analysis of the data and writing the manuscript All authors read and approved the final manuscript 16 Competing interests The authors declare ... as a standard measure and hence is incorporated as a means for comparing this study with other studies Carcass weight and final body weight were adjusted only for cohort effects (Additional file...
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Báo cáo y học: " Vgf is a novel biomarker associated with muscle weakness in amyotrophic lateral sclerosis (ALS), with a potential role in disease pathogenesis"
... Tkalych O, Nanno D, Garcia AL, Devi LA, Salton SR Quantification of Vgf- and pro-SAAS-derived peptides in endocrine tissues and the brain, and their regulation by diet and cold stress Brain Res 2006; ... immunocytochemically revealed that Vgf immunoreactive material in spinal cord motorneurons is already decreased in ~75 day old asymptomatic SOD-1 G9 3A- SOD1 ALS mice and continue to decrease as a function ... immunostaining in spinal cord dorsal neurons was expressed using arbitrary units Mouse Vgf radio immuno assay (RIA) C-terminal specific Vgf antibody (ab5901) was used in RIA analysis as previously described...
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